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Search term: YGL154C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LYS5
SGD link S000003122
Alternative ID YGL154C
Description Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine
Synonyms YGL154C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0945 AC-HYP-

KOGs classification KOGs description
METABOLISMMETABOLISM Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g02770_2 GI:15227031
Arabidopsis thaliana (Ath) At3g11470 GI:15229767
Caenorhabditis elegans (Cel) CE04885
(WBGene00020215)
GI:17569611 Q22171
Caenorhabditis elegans (Cel) CE06529
(WBGene00012142)
GI:17564880 Q22856
Homo sapiens (Hsa) Hs20357568 GI:14770303
Saccharomyces cerevisiae (Sce) YGL154c
(S000003122)
GI:6321284 P50113
Schizosaccharomyces pombe (Spo) SPAC17C9.02c GI:19115515 Q10474
Arabidopsis thaliana (Ath) At2g02770_2 GI:15227031
Arabidopsis thaliana (Ath) At3g11470 GI:15229767
Caenorhabditis elegans (Cel) CE04885
(WBGene00020215)
GI:17569611 Q22171
Caenorhabditis elegans (Cel) CE06529
(WBGene00012142)
GI:17564880 Q22856
Homo sapiens (Hsa) Hs20357568 GI:14770303
Saccharomyces cerevisiae (Sce) YGL154c
(S000003122)
GI:6321284 P50113
Schizosaccharomyces pombe (Spo) SPAC17C9.02c GI:19115515 Q10474


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g02770
GO:0005634 nucleus C
IDA
SpoSPAC17C9.02c
GO:0005737 cytoplasm C
ISS
SpoSPAC17C9.02c
TAS
SceS000003122
GO:0005829 cytosol C
IDA
SpoSPAC17C9.02c
GO:0008897 holo-[acyl-carrier-protein] synthase
activity
F
IDA
SceS000003122
SpoSPAC17C9.02c
GO:0016740 transferase activity F
ISS
AthAt3g11470
GO:0008152 metabolic process P
ISS
AthAt3g11470
GO:0009085 lysine biosynthetic process P
IDA
SpoSPAC17C9.02c
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00020215
GO:0018065 protein-cofactor linkage P
IDA
SceS000003122
GO:0019878 lysine biosynthetic process via aminoadipic
acid
P
TAS
SceS000003122
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00020215
GO:0040011 locomotion P
IMP
CelWBGene00020215

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48713

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) LYS5
(S000003122)
GI:6321284 P50113
Kluyveromyces lactis (Kla) KLLA0E08899g GI:50308697
Eremothecium gossypii (Ego) AGOS_AGR382W GI:45201478


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
TAS
SceS000003122
GO:0008897 holo-[acyl-carrier-protein] synthase
activity
F
IDA
SceS000003122
GO:0018065 protein-cofactor linkage P
IDA
SceS000003122
GO:0019878 lysine biosynthetic process via aminoadipic
acid
P
TAS
SceS000003122

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24597

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4693 AGR382W
Candida glabrata (Cgl) cgl1163 CAGL0E05104g
Debaryomyces hansenii (Dha) dha6765 DEHA0G23947g
Kluyveromyces lactis (Kla) kla3351 KLLA0E08899g
Saccharomyces cerevisiae (Sce) sce2249 YGL154C
(S000003122)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
TAS
SceS000003122
GO:0008897 holo-[acyl-carrier-protein] synthase
activity
F
IDA
SceS000003122
GO:0018065 protein-cofactor linkage P
IDA
SceS000003122
GO:0019878 lysine biosynthetic process via aminoadipic
acid
P
TAS
SceS000003122

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC17C9.02c
(Q10474)
YGL154C
(S000003122)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17C9.02c
GO:0005737 cytoplasm C
ISS
SpoSPAC17C9.02c
TAS
SceS000003122
GO:0005829 cytosol C
IDA
SpoSPAC17C9.02c
GO:0008897 holo-[acyl-carrier-protein] synthase
activity
F
IDA
SceS000003122
SpoSPAC17C9.02c
GO:0009085 lysine biosynthetic process P
IDA
SpoSPAC17C9.02c
GO:0018065 protein-cofactor linkage P
IDA
SceS000003122
GO:0019878 lysine biosynthetic process via aminoadipic
acid
P
TAS
SceS000003122

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