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Search term: YGL172W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NUP49
SGD link S000003140
Alternative ID YGL172W
Description Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes
Synonyms YGL172W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0845 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Nuclear pore complex, Nup98 component (sc Nup145/Nup100/Nup116)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g10390 GI:15218520
Arabidopsis thaliana (Ath) At1g59660 GI:15218866
Arabidopsis thaliana (Ath) At1g80680 GI:15220199
Arabidopsis thaliana (Ath) At3g10650 GI:15228349
Caenorhabditis elegans (Cel) CE10988_1 GI:17507541 O01576
Caenorhabditis elegans (Cel) CE13738
(WBGene00003793)		 GI:17509085 P91457
Caenorhabditis elegans (Cel) CE20315
(WBGene00003790)		 GI:17510275 Q9XWK3
Caenorhabditis elegans (Cel) CE28183 GI:17556885
Caenorhabditis elegans (Cel) CE28184 GI:17556883
Drosophila melanogaster (Dme) 7300534 GI:7300534
Drosophila melanogaster (Dme) 7301053 GI:7301053
Drosophila melanogaster (Dme) 7301054 GI:7301054
Homo sapiens (Hsa) Hs15147335
(NCOA5)		 GI:15147335 Q9HCD5
Homo sapiens (Hsa) Hs21264365
(NUP98)		 GI:21264365 Q9Y6J4
Homo sapiens (Hsa) Hs21264367 GI:21264367
Homo sapiens (Hsa) Hs21264369 GI:1709400
Homo sapiens (Hsa) Hs21264371 GI:21264371
Homo sapiens (Hsa) HsM11120678 GI:11120678
Saccharomyces cerevisiae (Sce) YDR192c
(S000002600)		 GI:6320399 P49686
Saccharomyces cerevisiae (Sce) YGL092w
(S000003060)		 GI:6321346 P49687
Saccharomyces cerevisiae (Sce) YGL172w
(S000003140)		 GI:6321266 Q02199
Saccharomyces cerevisiae (Sce) YKL068w
(S000001551)		 GI:6322782 Q02629
Saccharomyces cerevisiae (Sce) YMR047c
(S000004650)		 GI:6323691 Q02630
Schizosaccharomyces pombe (Spo) SPAC1486.05 GI:19115005 Q9UTK4
Schizosaccharomyces pombe (Spo) SPAC22G7.09c GI:19113970 Q09793
Encephalitozoon cuniculi (Ecu) ECU02g0460 GI:19073967 Q8SWE7
Encephalitozoon cuniculi (Ecu) ECU11g1820 GI:19074982 Q8SQR9
Arabidopsis thaliana (Ath) At1g10390 GI:15218520
Arabidopsis thaliana (Ath) At1g59660 GI:15218866
Arabidopsis thaliana (Ath) At1g80680 GI:15220199
Arabidopsis thaliana (Ath) At3g10650 GI:15228349
Caenorhabditis elegans (Cel) CE10988_1 GI:17507541 O01576
Caenorhabditis elegans (Cel) CE13738
(WBGene00003793)		 GI:17509085 P91457
Caenorhabditis elegans (Cel) CE20315
(WBGene00003790)		 GI:17510275 Q9XWK3
Caenorhabditis elegans (Cel) CE28183 GI:17556885
Caenorhabditis elegans (Cel) CE28184 GI:17556883
Drosophila melanogaster (Dme) 7300534 GI:7300534
Drosophila melanogaster (Dme) 7301053 GI:7301053
Drosophila melanogaster (Dme) 7301054 GI:7301054
Homo sapiens (Hsa) Hs15147335
(NCOA5)		 GI:15147335 Q9HCD5
Homo sapiens (Hsa) Hs21264365
(NUP98)		 GI:21264365 Q9Y6J4
Homo sapiens (Hsa) Hs21264367 GI:21264367
Homo sapiens (Hsa) Hs21264369 GI:1709400
Homo sapiens (Hsa) Hs21264371 GI:21264371
Homo sapiens (Hsa) HsM11120678 GI:11120678
Saccharomyces cerevisiae (Sce) YDR192c
(S000002600)		 GI:6320399 P49686
Saccharomyces cerevisiae (Sce) YGL092w
(S000003060)		 GI:6321346 P49687
Saccharomyces cerevisiae (Sce) YGL172w
(S000003140)		 GI:6321266 Q02199
Saccharomyces cerevisiae (Sce) YKL068w
(S000001551)		 GI:6322782 Q02629
Saccharomyces cerevisiae (Sce) YMR047c
(S000004650)		 GI:6323691 Q02630
Schizosaccharomyces pombe (Spo) SPAC1486.05 GI:19115005 Q9UTK4
Schizosaccharomyces pombe (Spo) SPAC22G7.09c GI:19113970 Q09793
Encephalitozoon cuniculi (Ecu) ECU02g0460 GI:19073967 Q8SWE7
Encephalitozoon cuniculi (Ecu) ECU11g1820 GI:19074982 Q8SQR9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
HsaNUP98
GO:0005575 cellular_component C
ND
AthAt3g10650
GO:0005634 nucleus C
IDA
AthAt1g80680
SpoSPAC22G7.09c
GO:0005635 nuclear envelope C
EXP
HsaNUP98
IDA
CelWBGene00003797
HsaNUP98
SceS000003140
GO:0005643 nuclear pore C
IDA
HsaNUP98
SceS000002600
S000003060
S000003140
S000001551
S000004650
NAS
HsaNUP98
TAS
SpoSPAC1486.05
SPAC22G7.09c
GO:0005654 nucleoplasm C
TAS
HsaNUP98
GO:0005737 cytoplasm C
IDA
SpoSPAC22G7.09c
GO:0031080 Nup107-160 complex C
IDA
HsaNUP98
SceS000003060
SpoSPAC1486.05
NAS
HsaNUP98
GO:0031965 nuclear membrane C
IDA
AthAt1g80680
SpoSPAC1486.05
SPAC22G7.09c
GO:0055125 Nic96 complex C
IDA
SceS000003140
GO:0055126 Nup82 complex C
IDA
SceS000004650
GO:0003674 molecular_function F
ND
AthAt3g10650
SpoSPAC22G7.09c
GO:0003723 RNA binding F
IDA
SceS000003060
GO:0005198 structural molecule activity F
TAS
SceS000002600
S000003060
S000003140
S000001551
S000004650
GO:0005215 transporter activity F
ISS
AthAt1g59660
At1g10390
TAS
HsaNUP98
GO:0005515 protein binding F
IPI
CelWBGene00003790
WBGene00003797
HsaNUP98
SpoSPAC1486.05
GO:0008233 peptidase activity F
ISS
SpoSPAC1486.05
GO:0015288 porin activity F
ISS
AthAt1g80680
GO:0017056 structural constituent of nuclear
pore		 F
NAS
HsaNUP98
GO:0000003 reproduction P
IMP
CelWBGene00003790
WBGene00003797
GO:0000054 ribosomal subunit export from nucleus P
RCA
SceS000003060
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000003140
GO:0000059 protein import into nucleus, docking P
NAS
HsaNUP98
GO:0000132 establishment of mitotic spindle
orientation		 P
IMP
CelWBGene00003790
WBGene00003797
GO:0002119 nematode larval development P
IMP
CelWBGene00003797
WBGene00003793
GO:0006260 DNA replication P
IMP
HsaNUP98
GO:0006388 tRNA splicing, via endonucleolytic cleavage and
ligation		 P
IMP
SceS000004650
S000003060
S000003140
GO:0006406 mRNA export from nucleus P
IGI
AthAt1g80680
IMP
SceS000003060
S000003140
S000004650
TAS
SceS000001551
S000002600
GO:0006407 rRNA export from nucleus P
ISS
SpoSPAC1486.05
TAS
SceS000002600
S000003060
S000003140
S000001551
S000004650
GO:0006408 snRNA export from nucleus P
TAS
SceS000003060
S000002600
S000003140
S000001551
S000004650
GO:0006409 tRNA export from nucleus P
IMP
SceS000004650
TAS
SceS000002600
S000003060
S000003140
S000001551
GO:0006414 translational elongation P
RCA
SceS000002600
GO:0006606 protein import into nucleus P
IMP
SceS000003060
S000003140
S000004650
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
SceS000002600
S000003060
S000004650
S000003140
S000001551
GO:0006608 snRNP protein import into nucleus P
TAS
SceS000002600
S000003060
S000003140
S000001551
S000004650
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
TAS
SceS000002600
S000003060
S000003140
S000001551
S000004650
GO:0006610 ribosomal protein import into nucleus P
TAS
SceS000002600
S000003060
S000003140
S000001551
S000004650
GO:0006611 protein export from nucleus P
TAS
SceS000003140
S000002600
S000003060
S000004650
S000001551
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00003797
WBGene00003790
GO:0006913 nucleocytoplasmic transport P
TAS
HsaNUP98
SpoSPAC22G7.09c
SPAC1486.05
GO:0006997 nucleus organization P
IMP
CelWBGene00003797
WBGene00003790
WBGene00003793
SpoSPAC1486.05
GO:0006999 nuclear pore organization P
IMP
SceS000003060
NAS
HsaNUP98
TAS
SceS000002600
S000004650
S000003140
S000001551
GO:0008150 biological_process P
ND
AthAt3g10650
GO:0009733 response to auxin stimulus P
IGI
AthAt1g80680
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003797
WBGene00003793
WBGene00003790
GO:0009870 defense response signaling pathway, resistance
gene-dependent		 P
IMP
AthAt1g80680
GO:0009910 negative regulation of flower development P
NAS
AthAt1g80680
GO:0040007 growth P
IMP
CelWBGene00003797
WBGene00003793
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003790
WBGene00003797
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003790
WBGene00003797
GO:0045184 establishment of protein localization P
RCA
SceS000003060
S000003140
S000004650
GO:0050000 chromosome localization P
IMP
SceS000003060
GO:0051301 cell division P
IMP
SpoSPAC1486.05
SPAC22G7.09c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39007

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) nup45
(SPAC22G7.09c)		 GI:19113970 Q09793
Saccharomyces cerevisiae (Sce) NUP49
(S000003140)		 GI:6321266 Q02199
Kluyveromyces lactis (Kla) KLLA0F22363g GI:50312095
Magnaporthe grisea (Mgr) MGG_10698 GI:145616595
Neurospora crassa (Ncr) NCU07655.1 GI:32415766


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC22G7.09c
GO:0005635 nuclear envelope C
IDA
SceS000003140
GO:0005643 nuclear pore C
IDA
SceS000003140
TAS
SpoSPAC22G7.09c
GO:0005737 cytoplasm C
IDA
SpoSPAC22G7.09c
GO:0031965 nuclear membrane C
IDA
SpoSPAC22G7.09c
GO:0055125 Nic96 complex C
IDA
SceS000003140
GO:0003674 molecular_function F
ND
SpoSPAC22G7.09c
GO:0005198 structural molecule activity F
TAS
SceS000003140
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000003140
GO:0006388 tRNA splicing, via endonucleolytic cleavage and
ligation		 P
IMP
SceS000003140
GO:0006406 mRNA export from nucleus P
IMP
SceS000003140
GO:0006407 rRNA export from nucleus P
TAS
SceS000003140
GO:0006408 snRNA export from nucleus P
TAS
SceS000003140
GO:0006409 tRNA export from nucleus P
TAS
SceS000003140
GO:0006606 protein import into nucleus P
IMP
SceS000003140
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
SceS000003140
GO:0006608 snRNP protein import into nucleus P
TAS
SceS000003140
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
TAS
SceS000003140
GO:0006610 ribosomal protein import into nucleus P
TAS
SceS000003140
GO:0006611 protein export from nucleus P
TAS
SceS000003140
GO:0006913 nucleocytoplasmic transport P
TAS
SpoSPAC22G7.09c
GO:0006999 nuclear pore organization P
TAS
SceS000003140
GO:0045184 establishment of protein localization P
RCA
SceS000003140
GO:0051301 cell division P
IMP
SpoSPAC22G7.09c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_8582

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1696 ADL045W
Candida glabrata (Cgl) cgl4333 CAGL0L05852g
Cryptococcus neoformans (Cne) cne2145 181.m08157
Dictyostelium discoideum (Ddi) ddi4342 DDB0215318
Debaryomyces hansenii (Dha) dha2107 DEHA0C15312g
Encephalitozoon cuniculi (Ecu) ecu1070 19074982
Gallus gallus (Gga) gga26664 ENSGALP00000022050
Kluyveromyces lactis (Kla) kla5079 KLLA0F22363g
Neurospora crassa (Ncr) ncr7453 NCU07655.2
Saccharomyces cerevisiae (Sce) sce2267 YGL172W
(S000003140)
Schizosaccharomyces pombe (Spo) spo265 SPAC22G7.09c Q09793
Yarrowia lipolytica (Yli) yli2648 YALI0C23166g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC22G7.09c
GO:0005635 nuclear envelope C
IDA
SceS000003140
GO:0005643 nuclear pore C
IDA
SceS000003140
TAS
SpoSPAC22G7.09c
GO:0005737 cytoplasm C
IDA
SpoSPAC22G7.09c
GO:0031965 nuclear membrane C
IDA
SpoSPAC22G7.09c
GO:0055125 Nic96 complex C
IDA
SceS000003140
GO:0003674 molecular_function F
ND
SpoSPAC22G7.09c
GO:0005198 structural molecule activity F
TAS
SceS000003140
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000003140
GO:0006388 tRNA splicing, via endonucleolytic cleavage and
ligation		 P
IMP
SceS000003140
GO:0006406 mRNA export from nucleus P
IMP
SceS000003140
GO:0006407 rRNA export from nucleus P
TAS
SceS000003140
GO:0006408 snRNA export from nucleus P
TAS
SceS000003140
GO:0006409 tRNA export from nucleus P
TAS
SceS000003140
GO:0006606 protein import into nucleus P
IMP
SceS000003140
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
SceS000003140
GO:0006608 snRNP protein import into nucleus P
TAS
SceS000003140
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
TAS
SceS000003140
GO:0006610 ribosomal protein import into nucleus P
TAS
SceS000003140
GO:0006611 protein export from nucleus P
TAS
SceS000003140
GO:0006913 nucleocytoplasmic transport P
TAS
SpoSPAC22G7.09c
GO:0006999 nuclear pore organization P
TAS
SceS000003140
GO:0045184 establishment of protein localization P
RCA
SceS000003140
GO:0051301 cell division P
IMP
SpoSPAC22G7.09c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC22G7.09c
(Q09793)		 YGL172W
(S000003140)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC22G7.09c
GO:0005635 nuclear envelope C
IDA
SceS000003140
GO:0005643 nuclear pore C
IDA
SceS000003140
TAS
SpoSPAC22G7.09c
GO:0005737 cytoplasm C
IDA
SpoSPAC22G7.09c
GO:0031965 nuclear membrane C
IDA
SpoSPAC22G7.09c
GO:0055125 Nic96 complex C
IDA
SceS000003140
GO:0003674 molecular_function F
ND
SpoSPAC22G7.09c
GO:0005198 structural molecule activity F
TAS
SceS000003140
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000003140
GO:0006388 tRNA splicing, via endonucleolytic cleavage and
ligation		 P
IMP
SceS000003140
GO:0006406 mRNA export from nucleus P
IMP
SceS000003140
GO:0006407 rRNA export from nucleus P
TAS
SceS000003140
GO:0006408 snRNA export from nucleus P
TAS
SceS000003140
GO:0006409 tRNA export from nucleus P
TAS
SceS000003140
GO:0006606 protein import into nucleus P
IMP
SceS000003140
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
SceS000003140
GO:0006608 snRNP protein import into nucleus P
TAS
SceS000003140
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
TAS
SceS000003140
GO:0006610 ribosomal protein import into nucleus P
TAS
SceS000003140
GO:0006611 protein export from nucleus P
TAS
SceS000003140
GO:0006913 nucleocytoplasmic transport P
TAS
SpoSPAC22G7.09c
GO:0006999 nuclear pore organization P
TAS
SceS000003140
GO:0045184 establishment of protein localization P
RCA
SceS000003140
GO:0051301 cell division P
IMP
SpoSPAC22G7.09c

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