Bahler Lab

Search term: YGL184C

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name STR3

SGD link S000003152

Alternative ID YGL184C

Description Cystathionine beta-lyase, converts cystathionine into homocysteine

Synonyms YGL184C

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0053 ACDHYP-

KOGs classification KOGs description

METABOLISM Cystathionine beta-lyases/cystathionine gamma-synthases

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0001950 plasma membrane enriched fraction C
IDA
Sce S000004294

GO:0005575 cellular_component C
ND
Sce S000003152
YLL058w
S000001952
Spo SPAC23A1.14c

GO:0005634 nucleus C
IDA
Sce S000003891
YML082w
Spo SPBC15D4.09c
SPBC428.11
ISS
Spo SPBC15D4.09c

GO:0005737 cytoplasm C
IDA
Sce YML082w
S000003891
S000004294
S000000010
YHR112c
ISS
Spo SPBC15D4.09c
SPBC428.11

GO:0005777 peroxisome C
ISS
Spo SPCC11E10.01

GO:0005829 cytosol C
IDA
Ath At1g64660
Spo SPBC15D4.09c
SPBC428.11

GO:0009507 chloroplast C
IDA
Ath At3g57050
At3g01120
ISS
Ath At3g57050

GO:0003824 catalytic activity F
ISS
Ath At1g64660

GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase
activity F
IDA
Sce S000004294
TAS
Sce S000004294
Spo SPBC428.11

GO:0003962 cystathionine gamma-synthase activity F
IDA
Ath At3g01120
IMP
Sce S000003891
ISS
Ath At3g01120
At1g33320
Sce YLL058w
Spo SPBC15D4.09c

GO:0004121 cystathionine beta-lyase activity F
IMP
Ath At3g57050
Sce S000003152
ISS
Sce YHR112c
S000001952
S000003152
Spo SPCC11E10.01

GO:0004123 cystathionine gamma-lyase activity F
IDA
Sce S000000010
IMP
Sce S000000010
NAS
Dme FBgn0000566
TAS
Dme FBgn0000566

GO:0004124 cysteine synthase activity F
IDA
Sce S000004294
ISS
Spo SPBC428.11

GO:0016829 lyase activity F
RCA
Sce S000003891

GO:0016846 carbon-sulfur lyase activity F
ISS
Sce YML082w

GO:0018826 methionine gamma-lyase activity F
IDA
Ath At1g64660

GO:0000096 sulfur amino acid metabolic process P
NAS
Dme FBgn0000566
TAS
Sce S000000010

GO:0006082 organic acid metabolic process P
RCA
Sce S000003891

GO:0006312 mitotic recombination P
IMP
Sce S000001952

GO:0006414 translational elongation P
RCA
Sce S000000010
S000001952

GO:0006519 cellular amino acid and derivative metabolic
process P
RCA
Sce S000003891
S000000010

GO:0006520 cellular amino acid metabolic process P
ISS
Ath At1g64660

GO:0006534 cysteine metabolic process P
ISS
Spo SPBC15D4.09c
TAS
Sce S000000010

GO:0006555 methionine metabolic process P
IMP
Sce S000004294
ISS
Spo SPBC428.11

GO:0006725 cellular aromatic compound metabolic
process P
RCA
Sce S000003891

GO:0006790 sulfur metabolic process P
IMP
Sce S000003891
ISS
Sce YLL058w
YHR112c
S000001952
YML082w
RCA
Sce S000000010
S000003152

GO:0006807 nitrogen compound metabolic process P
RCA
Sce S000003891
S000000010

GO:0006878 cellular copper ion homeostasis P
IEP
Sce S000001952

GO:0009086 methionine biosynthetic process P
IMP
Ath At3g01120
Sce S000003152
ISS
Ath At1g33320

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00022856

GO:0019279 L-methionine biosynthetic process from
L-homoserine via cystathionine P
IC
Spo SPCC11E10.01
TAS
Ath At3g57050

GO:0019281 L-methionine biosynthetic process from homoserine
via O-succinyl-L-homoserine and
cystathionine P
ISS
Spo SPBC15D4.09c

GO:0019343 cysteine biosynthetic process via
cystathionine P
IMP
Sce S000000010

GO:0019344 cysteine biosynthetic process P
IMP
Sce S000000010
ISS
Spo SPBC428.11
TAS
Sce S000004294

GO:0019346 transsulfuration P
IMP
Sce S000000010
S000003891
S000003152

GO:0019458 methionine catabolic process via
2-oxobutanoate P
TAS
Ath At1g64660

GO:0046483 heterocycle metabolic process P
RCA
Sce S000000010
S000003152

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

68693

Species Gene ID NCBI link UniProt link

Schizosaccharomyces pombe (Spo) SPCC11E10.01 GI:63054442 O94350

Saccharomyces cerevisiae (Sce) STR3
(S000003152) GI:6321254 P53101

Kluyveromyces lactis (Kla) KLLA0C17028g GI:50306001

Eremothecium gossypii (Ego) AGOS_ACL059C GI:45185629

Magnaporthe grisea (Mgr) MGG_07074 GI:39971517

Neurospora crassa (Ncr) NCU07987.1 GI:32416430

Arabidopsis thaliana (Ath) CBL GI:15230203

Oryza sativa (Osa) Os06g0175800 GI:115466704

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Ath CBL
Sce S000003152

GO:0005737 cytoplasm C
IDA
Ath CBL

GO:0005773 vacuole C
IDA
Ath CBL

GO:0005777 peroxisome C
ISS
Spo SPCC11E10.01

GO:0005886 plasma membrane C
IDA
Ath CBL

GO:0008287 protein serine/threonine phosphatase
complex C
ISS
Ath CBL

GO:0009507 chloroplast C
IDA
Ath CBL
ISS
Ath CBL

GO:0009705 plant-type vacuole membrane C
IDA
Ath CBL

GO:0016020 membrane C
IDA
Ath CBL

GO:0022626 cytosolic ribosome C
IDA
Ath CBL

GO:0004121 cystathionine beta-lyase activity F
IMP
Ath CBL
Sce S000003152
ISS
Sce S000003152
Spo SPCC11E10.01

GO:0005509 calcium ion binding F
IDA
Ath CBL
ISS
Ath CBL

GO:0005513 detection of calcium ion P
ISS
Ath CBL

GO:0006790 sulfur metabolic process P
RCA
Sce S000003152

GO:0006950 response to stress P
IPI
Ath CBL

GO:0006970 response to osmotic stress P
IMP
Ath CBL
TAS
Ath CBL

GO:0009086 methionine biosynthetic process P
IMP
Sce S000003152

GO:0009409 response to cold P
IEP
Ath CBL

GO:0009414 response to water deprivation P
IMP
Ath CBL

GO:0009651 response to salt stress P
IEP
Ath CBL
IMP
Ath CBL

GO:0009738 abscisic acid mediated signaling
pathway P
TAS
Ath CBL

GO:0010107 potassium ion import P
IGI
Ath CBL

GO:0010118 stomatal movement P
IGI
Ath CBL

GO:0019279 L-methionine biosynthetic process from
L-homoserine via cystathionine P
IC
Spo SPCC11E10.01
TAS
Ath CBL

GO:0019346 transsulfuration P
IMP
Sce S000003152

GO:0019722 calcium-mediated signaling P
ISS
Ath CBL
TAS
Ath CBL

GO:0042538 hyperosmotic salinity response P
IMP
Ath CBL

GO:0046483 heterocycle metabolic process P
RCA
Sce S000003152

GO:2000021 regulation of ion homeostasis P
IMP
Ath CBL

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KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0053	ACDHYP-

KOGs classification	KOGs description
METABOLISM	Cystathionine beta-lyases/cystathionine gamma-synthases

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g33320	GI:15217498
Arabidopsis thaliana (Ath)	At1g64660	GI:15217709
Arabidopsis thaliana (Ath)	At3g01120	GI:15232042
Arabidopsis thaliana (Ath)	At3g57050	GI:15230203
Caenorhabditis elegans (Cel)	CE07648 (WBGene00022856)	GI:17538055	P55216
Caenorhabditis elegans (Cel)	CE15884 (WBGene00009048)	GI:17560056	O45391
Caenorhabditis elegans (Cel)	CE17400	GI:17505573
Drosophila melanogaster (Dme)	7302582 (FBgn0000566)	GI:19922554
Homo sapiens (Hsa)	Hs21361334	GI:12314252	P32929
Homo sapiens (Hsa)	HsM4503125	GI:4503125
Saccharomyces cerevisiae (Sce)	YAL012w (S000000010)	GI:6319307	P31373
Saccharomyces cerevisiae (Sce)	YFR055w (S000001952)	GI:14318580	P43623
Saccharomyces cerevisiae (Sce)	YGL184c (S000003152)	GI:6321254	P53101
Saccharomyces cerevisiae (Sce)	YHR112c	GI:6321904	P38716
Saccharomyces cerevisiae (Sce)	YJR130c (S000003891)	GI:6322590	P47164
Saccharomyces cerevisiae (Sce)	YLL058w	GI:6322970	Q12198
Saccharomyces cerevisiae (Sce)	YLR303w (S000004294)	GI:6323333	P06106
Saccharomyces cerevisiae (Sce)	YML082w	GI:6323557	Q04533
Schizosaccharomyces pombe (Spo)	SPAC23A1.14c	GI:19115355	O42851
Schizosaccharomyces pombe (Spo)	SPBC15D4.09c	GI:19113041	O74314
Schizosaccharomyces pombe (Spo)	SPBC428.11	GI:19111981	O13326
Schizosaccharomyces pombe (Spo)	SPCC11E10.01	GI:19075697	O94350
Arabidopsis thaliana (Ath)	At1g33320	GI:15217498
Arabidopsis thaliana (Ath)	At1g64660	GI:15217709
Arabidopsis thaliana (Ath)	At3g01120	GI:15232042
Arabidopsis thaliana (Ath)	At3g57050	GI:15230203
Caenorhabditis elegans (Cel)	CE07648 (WBGene00022856)	GI:17538055	P55216
Caenorhabditis elegans (Cel)	CE15884 (WBGene00009048)	GI:17560056	O45391
Caenorhabditis elegans (Cel)	CE17400	GI:17505573
Drosophila melanogaster (Dme)	7302582 (FBgn0000566)	GI:19922554
Homo sapiens (Hsa)	Hs21361334	GI:12314252	P32929
Homo sapiens (Hsa)	HsM4503125	GI:4503125
Saccharomyces cerevisiae (Sce)	YAL012w (S000000010)	GI:6319307	P31373
Saccharomyces cerevisiae (Sce)	YFR055w (S000001952)	GI:14318580	P43623
Saccharomyces cerevisiae (Sce)	YGL184c (S000003152)	GI:6321254	P53101
Saccharomyces cerevisiae (Sce)	YHR112c	GI:6321904	P38716
Saccharomyces cerevisiae (Sce)	YJR130c (S000003891)	GI:6322590	P47164
Saccharomyces cerevisiae (Sce)	YLL058w	GI:6322970	Q12198
Saccharomyces cerevisiae (Sce)	YLR303w (S000004294)	GI:6323333	P06106
Saccharomyces cerevisiae (Sce)	YML082w	GI:6323557	Q04533
Schizosaccharomyces pombe (Spo)	SPAC23A1.14c	GI:19115355	O42851
Schizosaccharomyces pombe (Spo)	SPBC15D4.09c	GI:19113041	O74314
Schizosaccharomyces pombe (Spo)	SPBC428.11	GI:19111981	O13326
Schizosaccharomyces pombe (Spo)	SPCC11E10.01	GI:19075697	O94350
Arabidopsis thaliana (Ath)	At1g33320	GI:15217498
Arabidopsis thaliana (Ath)	At1g64660	GI:15217709
Arabidopsis thaliana (Ath)	At3g01120	GI:15232042
Arabidopsis thaliana (Ath)	At3g57050	GI:15230203
Caenorhabditis elegans (Cel)	CE07648 (WBGene00022856)	GI:17538055	P55216
Caenorhabditis elegans (Cel)	CE15884 (WBGene00009048)	GI:17560056	O45391
Caenorhabditis elegans (Cel)	CE17400	GI:17505573
Drosophila melanogaster (Dme)	7302582 (FBgn0000566)	GI:19922554
Homo sapiens (Hsa)	Hs21361334	GI:12314252	P32929
Homo sapiens (Hsa)	HsM4503125	GI:4503125
Saccharomyces cerevisiae (Sce)	YAL012w (S000000010)	GI:6319307	P31373
Saccharomyces cerevisiae (Sce)	YFR055w (S000001952)	GI:14318580	P43623
Saccharomyces cerevisiae (Sce)	YGL184c (S000003152)	GI:6321254	P53101
Saccharomyces cerevisiae (Sce)	YHR112c	GI:6321904	P38716
Saccharomyces cerevisiae (Sce)	YJR130c (S000003891)	GI:6322590	P47164
Saccharomyces cerevisiae (Sce)	YLL058w	GI:6322970	Q12198
Saccharomyces cerevisiae (Sce)	YLR303w (S000004294)	GI:6323333	P06106
Saccharomyces cerevisiae (Sce)	YML082w	GI:6323557	Q04533
Schizosaccharomyces pombe (Spo)	SPAC23A1.14c	GI:19115355	O42851
Schizosaccharomyces pombe (Spo)	SPBC15D4.09c	GI:19113041	O74314
Schizosaccharomyces pombe (Spo)	SPBC428.11	GI:19111981	O13326
Schizosaccharomyces pombe (Spo)	SPCC11E10.01	GI:19075697	O94350

Species	Gene ID	NCBI link	UniProt link
Schizosaccharomyces pombe (Spo)	SPCC11E10.01	GI:63054442	O94350
Saccharomyces cerevisiae (Sce)	STR3 (S000003152)	GI:6321254	P53101
Kluyveromyces lactis (Kla)	KLLA0C17028g	GI:50306001
Eremothecium gossypii (Ego)	AGOS_ACL059C	GI:45185629
Magnaporthe grisea (Mgr)	MGG_07074	GI:39971517
Neurospora crassa (Ncr)	NCU07987.1	GI:32416430
Arabidopsis thaliana (Ath)	CBL	GI:15230203
Oryza sativa (Osa)	Os06g0175800	GI:115466704