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Search term: YGL213C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SKI8
SGD link S000003181
Alternative ID YGL213C
Description Ski complex component and WD-repeat protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; also required for meiotic double-strand break recombination; null mutants have superkiller phenotype
Synonyms YGL213C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4155 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED FOG: WD40 repeat

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g24130 GI:15221675
Arabidopsis thaliana (Ath) At1g24530 GI:18395507
Arabidopsis thaliana (Ath) At1g47610 GI:15220271
Arabidopsis thaliana (Ath) At1g49450 GI:15222143
Arabidopsis thaliana (Ath) At2g26490 GI:15225317
Arabidopsis thaliana (Ath) At3g18950 GI:15230244
Arabidopsis thaliana (Ath) At3g50390 GI:15229740
Arabidopsis thaliana (Ath) At3g51930 GI:15231088
Arabidopsis thaliana (Ath) At4g11270 GI:15237124
Arabidopsis thaliana (Ath) At4g29830 GI:15233721
Arabidopsis thaliana (Ath) At4g34380 GI:15235354
Arabidopsis thaliana (Ath) At5g50120 GI:15240616
Caenorhabditis elegans (Cel) CE18408 GI:17541736
Caenorhabditis elegans (Cel) CE26171 GI:17556178
Caenorhabditis elegans (Cel) CE27119
(WBGene00008533)		 GI:17506519
Drosophila melanogaster (Dme) 7290231 GI:7290231
Drosophila melanogaster (Dme) 7299285 GI:4972734
Drosophila melanogaster (Dme) 7300980 GI:7300980
Drosophila melanogaster (Dme) 7301704 GI:7301704
Drosophila melanogaster (Dme) 7302353 GI:7302353
Drosophila melanogaster (Dme) 7302600 GI:7302600
Homo sapiens (Hsa) Hs13236597 GI:13236597
Homo sapiens (Hsa) Hs13376840
(WDR61)		 GI:13376840 Q9GZS3
Homo sapiens (Hsa) Hs16579890 GI:16579890
Homo sapiens (Hsa) Hs16579892 GI:16579892
Homo sapiens (Hsa) Hs18553366_1 GI:18553366
Homo sapiens (Hsa) Hs21536371_2 GI:13649631
Homo sapiens (Hsa) Hs22054346 GI:22054346
Homo sapiens (Hsa) Hs4502123_2 GI:4502123 Q9UJ65
Homo sapiens (Hsa) Hs7108333_2 GI:7108333 Q9UJ65
Homo sapiens (Hsa) HsM6005894_2 GI:6005894
Saccharomyces cerevisiae (Sce) YDR030c
(S000002437)		 GI:6320233 Q12021
Saccharomyces cerevisiae (Sce) YGL213c
(S000003181)		 GI:6321225 Q02793
Saccharomyces cerevisiae (Sce) YJL112w
(S000003648)		 GI:6322349 P47025
Saccharomyces cerevisiae (Sce) YKR036c
(S000001744)		 GI:6322889
Saccharomyces cerevisiae (Sce) YNL253w
(S000005197)		 GI:6324076 P53851
Schizosaccharomyces pombe (Spo) SPBC32F12.02 GI:19112937 Q09150


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000003181
GO:0000346 transcription export complex C
IPI
SceS000005197
GO:0000347 THO complex C
RCA
SceS000005197
GO:0000445 THO complex part of transcription export
complex		 C
RCA
SceS000005197
GO:0000446 nucleoplasmic THO complex C
RCA
SceS000005197
GO:0005575 cellular_component C
ND
AthAt1g49450
At3g18950
GO:0005634 nucleus C
IC
SceS000002437
IDA
SpoSPBC32F12.02
GO:0005739 mitochondrion C
IDA
SceS000001744
S000003648
GO:0005741 mitochondrial outer membrane C
IDA
SceS000003648
GO:0005829 cytosol C
IDA
AthAt4g11270
SpoSPBC32F12.02
GO:0005834 heterotrimeric G-protein complex C
ISS
AthAt1g24130
At1g47610
At4g34380
At5g50120
At2g26490
At3g50390
At4g29830
At1g24530
GO:0005886 plasma membrane C
IDA
AthAt1g24530
GO:0030014 CCR4-NOT complex C
IDA
SceS000001744
GO:0043234 protein complex C
NAS
SpoSPBC32F12.02
GO:0055087 Ski complex C
IDA
SceS000003181
IPI
SceS000003181
ISS
SpoSPBC32F12.02
GO:0080008 CUL4 RING ubiquitin ligase complex C
IPI
AthAt4g29830
ISS
AthAt3g51930
GO:0000166 nucleotide binding F
ISS
AthAt1g47610
At4g34380
At4g11270
At5g50120
At1g49450
At2g26490
At3g50390
At1g24530
At1g24130
At4g29830
At3g18950
At3g51930
GO:0003674 molecular_function F
ND
SceS000005197
S000002437
S000003181
S000003648
S000001744
SpoSPBC32F12.02
GO:0005515 protein binding F
IPI
AthAt4g29830
HsaWDR61
GO:0000002 mitochondrial genome maintenance P
IGI
SceS000003648
IMP
SceS000003648
GO:0000266 mitochondrial fission P
IGI
SceS000003648
IMP
SceS000003648
S000001744
IPI
SceS000003648
S000001744
GO:0006281 DNA repair P
IGI
SceS000002437
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SceS000001744
IPI
SceS000001744
GO:0006402 mRNA catabolic process P
ISS
SpoSPBC32F12.02
GO:0006406 mRNA export from nucleus P
IC
SceS000005197
GO:0006461 protein complex assembly P
IMP
SceS000003181
GO:0007131 reciprocal meiotic recombination P
IGI
SceS000003181
IMP
SceS000003181
SpoSPBC32F12.02
IPI
SceS000003181
GO:0008150 biological_process P
ND
AthAt3g18950
At4g34380
At1g49450
At2g26490
At1g47610
At5g50120
At3g50390
At4g11270
At1g24530
At1g24130
GO:0009910 negative regulation of flower development P
IGI
AthAt4g29830
IMP
AthAt4g29830
GO:0010452 histone H3-K36 methylation P
IMP
AthAt4g29830
GO:0016559 peroxisome fission P
IGI
SceS000001744
S000003648
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000003181
GO:0051049 regulation of transport P
RCA
SceS000003181
GO:0051568 histone H3-K4 methylation P
IMP
AthAt4g29830
GO:0065004 protein-DNA complex assembly P
IMP
SceS000003181
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003181
IMP
SceS000003181
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000003181

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38992

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SKI8
(S000003181)		 GI:6321225 Q02793
Kluyveromyces lactis (Kla) KLLA0A01650g GI:50302277
Eremothecium gossypii (Ego) AGOS_AER439W GI:45191040


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000003181
GO:0055087 Ski complex C
IDA
SceS000003181
IPI
SceS000003181
GO:0003674 molecular_function F
ND
SceS000003181
GO:0006461 protein complex assembly P
IMP
SceS000003181
GO:0007131 reciprocal meiotic recombination P
IGI
SceS000003181
IMP
SceS000003181
IPI
SceS000003181
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000003181
GO:0051049 regulation of transport P
RCA
SceS000003181
GO:0065004 protein-DNA complex assembly P
IMP
SceS000003181
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003181
IMP
SceS000003181
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000003181

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24683

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2939 AER439W
Candida glabrata (Cgl) cgl2828 CAGL0I07073g
Debaryomyces hansenii (Dha) dha221 DEHA0A04994g
Kluyveromyces lactis (Kla) kla69 KLLA0A01650g
Saccharomyces cerevisiae (Sce) sce2309 YGL213C
(S000003181)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000003181
GO:0055087 Ski complex C
IDA
SceS000003181
IPI
SceS000003181
GO:0003674 molecular_function F
ND
SceS000003181
GO:0006461 protein complex assembly P
IMP
SceS000003181
GO:0007131 reciprocal meiotic recombination P
IGI
SceS000003181
IMP
SceS000003181
IPI
SceS000003181
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000003181
GO:0051049 regulation of transport P
RCA
SceS000003181
GO:0065004 protein-DNA complex assembly P
IMP
SceS000003181
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003181
IMP
SceS000003181
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000003181

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC32F12.02
(Q09150)		 YGL213C
(S000003181)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000003181
GO:0005634 nucleus C
IDA
SpoSPBC32F12.02
GO:0005829 cytosol C
IDA
SpoSPBC32F12.02
GO:0043234 protein complex C
NAS
SpoSPBC32F12.02
GO:0055087 Ski complex C
IDA
SceS000003181
IPI
SceS000003181
ISS
SpoSPBC32F12.02
GO:0003674 molecular_function F
ND
SceS000003181
SpoSPBC32F12.02
GO:0006402 mRNA catabolic process P
ISS
SpoSPBC32F12.02
GO:0006461 protein complex assembly P
IMP
SceS000003181
GO:0007131 reciprocal meiotic recombination P
IGI
SceS000003181
IMP
SceS000003181
SpoSPBC32F12.02
IPI
SceS000003181
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000003181
GO:0051049 regulation of transport P
RCA
SceS000003181
GO:0065004 protein-DNA complex assembly P
IMP
SceS000003181
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003181
IMP
SceS000003181
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000003181

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