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Search term: YGL248W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDE1
SGD link S000003217
Alternative ID YGL248W
Description Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation
Synonyms YGL248W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
21753

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) cgs2
(SPCC285.09c)
GI:19075837 P36599
Saccharomyces cerevisiae (Sce) PDE1
(S000003217)
GI:6321189
Kluyveromyces lactis (Kla) KLLA0D11528g GI:50307193
Eremothecium gossypii (Ego) AGOS_AFR259W GI:45198777
Magnaporthe grisea (Mgr) MGG_07707 GI:39972825
Neurospora crassa (Ncr) NCU00237.1 GI:32403420


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003217
GO:0005634 nucleus C
IDA
SpoSPCC285.09c
GO:0005829 cytosol C
IDA
SpoSPCC285.09c
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity
F
IGI
SpoSPCC285.09c
TAS
SceS000003217
GO:0006198 cAMP catabolic process P
ISS
SpoSPCC285.09c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPCC285.09c
GO:0007194 negative regulation of adenylate cyclase
activity
P
TAS
SpoSPCC285.09c
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IMP
SpoSPCC285.09c
GO:0019933 cAMP-mediated signaling P
IMP
SceS000003217
SpoSPCC285.09c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPCC285.09c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11618

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago3451 AFR259W
Candida glabrata (Cgl) cgl2398 CAGL0H07667g
Dictyostelium discoideum (Ddi) ddi8139 DDB0188281
Dictyostelium discoideum (Ddi) ddi13091 DDB0219974
Debaryomyces hansenii (Dha) dha5075 DEHA0F15521g
Kluyveromyces lactis (Kla) kla2574 KLLA0D11528g
Neurospora crassa (Ncr) ncr228 NCU00237.2
Saccharomyces cerevisiae (Sce) sce2345 YGL248W
(S000003217)
Schizosaccharomyces pombe (Spo) spo1682 SPCC285.09c P36599
Yarrowia lipolytica (Yli) yli5216 YALI0E32527g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003217
GO:0005634 nucleus C
IDA
SpoSPCC285.09c
GO:0005829 cytosol C
IDA
SpoSPCC285.09c
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity
F
IGI
SpoSPCC285.09c
TAS
SceS000003217
GO:0006198 cAMP catabolic process P
ISS
SpoSPCC285.09c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPCC285.09c
GO:0007194 negative regulation of adenylate cyclase
activity
P
TAS
SpoSPCC285.09c
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IMP
SpoSPCC285.09c
GO:0019933 cAMP-mediated signaling P
IMP
SceS000003217
SpoSPCC285.09c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPCC285.09c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC285.09c
(P36599)
YGL248W
(S000003217)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003217
GO:0005634 nucleus C
IDA
SpoSPCC285.09c
GO:0005829 cytosol C
IDA
SpoSPCC285.09c
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity
F
IGI
SpoSPCC285.09c
TAS
SceS000003217
GO:0006198 cAMP catabolic process P
ISS
SpoSPCC285.09c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPCC285.09c
GO:0007194 negative regulation of adenylate cyclase
activity
P
TAS
SpoSPCC285.09c
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IMP
SpoSPCC285.09c
GO:0019933 cAMP-mediated signaling P
IMP
SceS000003217
SpoSPCC285.09c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPCC285.09c

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s.khadayate@ucl.ac.uk