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Search term: YGL251C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HFM1
SGD link S000003220
Alternative ID YGL251C
Description Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
Synonyms YGL251C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0952 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA/RNA helicase MER3/SLH1, DEAD-box superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g27730 GI:15232253
Arabidopsis thaliana (Ath) At5g61140 GI:15240150
Caenorhabditis elegans (Cel) CE20305
(WBGene00013191)
GI:17537519
Drosophila melanogaster (Dme) 7300033 GI:7300033
Homo sapiens (Hsa) Hs14747366 GI:14747366
Homo sapiens (Hsa) Hs18548973 GI:18548973
Saccharomyces cerevisiae (Sce) YGL251c
(S000003220)
GI:9755332 P51979
Saccharomyces cerevisiae (Sce) YGR271w
(S000003503)
GI:6321710 P53327
Schizosaccharomyces pombe (Spo) SPBC13G1.10c GI:19113352 O60072
Encephalitozoon cuniculi (Ecu) ECU07g0830 GI:19074505 Q8SRJ6
Arabidopsis thaliana (Ath) At3g27730 GI:15232253
Arabidopsis thaliana (Ath) At5g61140 GI:15240150
Caenorhabditis elegans (Cel) CE20305
(WBGene00013191)
GI:17537519
Drosophila melanogaster (Dme) 7300033 GI:7300033
Homo sapiens (Hsa) Hs14747366 GI:14747366
Homo sapiens (Hsa) Hs18548973 GI:18548973
Saccharomyces cerevisiae (Sce) YGL251c
(S000003220)
GI:9755332 P51979
Saccharomyces cerevisiae (Sce) YGR271w
(S000003503)
GI:6321710 P53327
Schizosaccharomyces pombe (Spo) SPBC13G1.10c GI:19113352 O60072
Encephalitozoon cuniculi (Ecu) ECU07g0830 GI:19074505 Q8SRJ6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003220
GO:0005737 cytoplasm C
IDA
SceS000003503
ISS
SpoSPBC13G1.10c
GO:0005829 cytosol C
IDA
SpoSPBC13G1.10c
GO:0003678 DNA helicase activity F
IDA
SceS000003220
ISS
AthAt3g27730
GO:0003724 RNA helicase activity F
ISS
SceS000003503
GO:0004004 ATP-dependent RNA helicase activity F
ISS
SpoSPBC13G1.10c
GO:0005524 ATP binding F
ISS
AthAt3g27730
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt3g27730
At5g61140
GO:0016887 ATPase activity F
RCA
SceS000003220
GO:0006268 DNA unwinding involved in replication P
IDA
SceS000003220
GO:0006417 regulation of translation P
IGI
SceS000003503
IMP
SceS000003503
ISS
SpoSPBC13G1.10c
GO:0007126 meiosis P
IDA
SceS000003220
GO:0007129 synapsis P
IGI
SceS000003220
IMP
SceS000003220
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt3g27730
SceS000003220
GO:0051026 chiasma assembly P
IMP
AthAt3g27730

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117795

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HFM1
(S000003220)
GI:9755332 P51979
Kluyveromyces lactis (Kla) KLLA0D11462g GI:50307187
Magnaporthe grisea (Mgr) MGG_05900 GI:145603673
Neurospora crassa (Ncr) NCU09793.1 GI:32419999


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003220
GO:0003678 DNA helicase activity F
IDA
SceS000003220
GO:0016887 ATPase activity F
RCA
SceS000003220
GO:0006268 DNA unwinding involved in replication P
IDA
SceS000003220
GO:0007126 meiosis P
IDA
SceS000003220
GO:0007129 synapsis P
IGI
SceS000003220
IMP
SceS000003220
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000003220

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_19817

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Candida glabrata (Cgl) cgl2395 CAGL0H07601g
Cryptococcus neoformans (Cne) cne135 162.m02678
Debaryomyces hansenii (Dha) dha4776 DEHA0F08877g
Kluyveromyces lactis (Kla) kla2571 KLLA0D11462g
Neurospora crassa (Ncr) ncr9537 NCU09793.2
Saccharomyces cerevisiae (Sce) sce2348 YGL251C
(S000003220)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003220
GO:0003678 DNA helicase activity F
IDA
SceS000003220
GO:0016887 ATPase activity F
RCA
SceS000003220
GO:0006268 DNA unwinding involved in replication P
IDA
SceS000003220
GO:0007126 meiosis P
IDA
SceS000003220
GO:0007129 synapsis P
IGI
SceS000003220
IMP
SceS000003220
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000003220

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s.khadayate@ucl.ac.uk