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Search term: YGL256W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ADH4
SGD link S000003225
Alternative ID YGL256W
Description Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency
Synonyms YGL256W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3857 -CDHYP-

KOGs classification KOGs description
METABOLISM Alcohol dehydrogenase, class IV

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE24222
(WBGene00012608)		 GI:17537053 Q9U2M4
Drosophila melanogaster (Dme) 7291405 GI:7291405
Homo sapiens (Hsa) Hs21389519 GI:16552547 Q8IWW8
Saccharomyces cerevisiae (Sce) YGL256w
(S000003225)		 GI:6321181
Schizosaccharomyces pombe (Spo) SPAC5H10.06c GI:19113731 Q09669


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003225
SpoSPAC5H10.06c
ISS
SpoSPAC5H10.06c
GO:0004022 alcohol dehydrogenase (NAD) activity F
IDA
SceS000003225
IMP
SceS000003225
GO:0004023 alcohol dehydrogenase activity, metal
ion-independent		 F
IMP
SpoSPAC5H10.06c
GO:0004024 alcohol dehydrogenase activity,
zinc-dependent		 F
ISS
SpoSPAC5H10.06c
GO:0000947 amino acid catabolic process to alcohol via
Ehrlich pathway		 P
IGI
SceS000003225
GO:0006113 fermentation P
IMP
SceS000003225
GO:0019655 glucose catabolic process to ethanol P
IMP
SpoSPAC5H10.06c
GO:0034224 cellular response to zinc ion starvation P
IEP
SpoSPAC5H10.06c
GO:0055069 zinc ion homeostasis P
IEP
SpoSPAC5H10.06c
GO:0071276 cellular response to cadmium ion P
IEP
SpoSPAC5H10.06c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74667

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) adh4
(SPAC5H10.06c)		 GI:19113731 Q09669
Saccharomyces cerevisiae (Sce) ADH4
(S000003225)		 GI:6321181
Kluyveromyces lactis (Kla) KLLA0C19382g GI:50306205


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003225
SpoSPAC5H10.06c
ISS
SpoSPAC5H10.06c
GO:0004022 alcohol dehydrogenase (NAD) activity F
IDA
SceS000003225
IMP
SceS000003225
GO:0004023 alcohol dehydrogenase activity, metal
ion-independent		 F
IMP
SpoSPAC5H10.06c
GO:0004024 alcohol dehydrogenase activity,
zinc-dependent		 F
ISS
SpoSPAC5H10.06c
GO:0000947 amino acid catabolic process to alcohol via
Ehrlich pathway		 P
IGI
SceS000003225
GO:0006113 fermentation P
IMP
SceS000003225
GO:0019655 glucose catabolic process to ethanol P
IMP
SpoSPAC5H10.06c
GO:0034224 cellular response to zinc ion starvation P
IEP
SpoSPAC5H10.06c
GO:0055069 zinc ion homeostasis P
IEP
SpoSPAC5H10.06c
GO:0071276 cellular response to cadmium ion P
IEP
SpoSPAC5H10.06c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1129

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga13888 ENSANGP00000001041
Anopheles gambiae (Aga) aga2092 ENSANGP00000011329
Arabidopsis thaliana (Ath) ath13964 At3g17160.1
Caenorhabditis elegans (Cel) cel18369 Y38F1A.6
(CE24222;
WBGene00012608)
Cryptococcus neoformans (Cne) cne1979 181.m07960
Dictyostelium discoideum (Ddi) ddi8959 DDB0219524
Drosophila melanogaster (Dme) dme6522 CG3425-PA
(FBgn0017482)
Escherichia coli (Eco) eco1204 16129202
Escherichia coli (Eco) eco2706 16130706
Escherichia coli (Eco) eco2374 49176224
Escherichia coli (Eco) eco3469 49176377
Gallus gallus (Gga) gga27072 ENSGALP00000022899
(ADHFE1)
Homo sapiens (Hsa) hsa30366 ENSP00000276576
(ADHFE1)		 C9J0C8
Kluyveromyces lactis (Kla) kla2064 KLLA0C19382g
Mus musculus (Mmu) mmu26 ENSMUSP00000027044
(MGI:1923437)		 Q8R0N6-1
Neurospora crassa (Ncr) ncr3954 NCU04078.2
Rattus norvegicus (Rno) rno22647 ENSRNOP00000009462
(RGD:1308863)		 Q4QQW3
Saccharomyces cerevisiae (Sce) sce2353 YGL256W
(S000003225)
Schizosaccharomyces pombe (Spo) spo807 SPAC5H10.06c Q09669
Yarrowia lipolytica (Yli) yli4513 YALI0E15818g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g17160
GO:0005739 mitochondrion C
IDA
MmuMGI:1923437
SceS000003225
SpoSPAC5H10.06c
ISS
SpoSPAC5H10.06c
GO:0003674 molecular_function F
ND
AthAt3g17160
MmuMGI:1923437
GO:0004022 alcohol dehydrogenase (NAD) activity F
IDA
SceS000003225
IMP
SceS000003225
GO:0004023 alcohol dehydrogenase activity, metal
ion-independent		 F
IMP
SpoSPAC5H10.06c
GO:0004024 alcohol dehydrogenase activity,
zinc-dependent		 F
ISS
SpoSPAC5H10.06c
GO:0000947 amino acid catabolic process to alcohol via
Ehrlich pathway		 P
IGI
SceS000003225
GO:0006113 fermentation P
IMP
SceS000003225
GO:0008150 biological_process P
ND
AthAt3g17160
MmuMGI:1923437
GO:0019655 glucose catabolic process to ethanol P
IMP
SpoSPAC5H10.06c
GO:0034224 cellular response to zinc ion starvation P
IEP
SpoSPAC5H10.06c
GO:0055069 zinc ion homeostasis P
IEP
SpoSPAC5H10.06c
GO:0071276 cellular response to cadmium ion P
IEP
SpoSPAC5H10.06c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC5H10.06c
(Q09669)		 YGL256W
(S000003225)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003225
SpoSPAC5H10.06c
ISS
SpoSPAC5H10.06c
GO:0004022 alcohol dehydrogenase (NAD) activity F
IDA
SceS000003225
IMP
SceS000003225
GO:0004023 alcohol dehydrogenase activity, metal
ion-independent		 F
IMP
SpoSPAC5H10.06c
GO:0004024 alcohol dehydrogenase activity,
zinc-dependent		 F
ISS
SpoSPAC5H10.06c
GO:0000947 amino acid catabolic process to alcohol via
Ehrlich pathway		 P
IGI
SceS000003225
GO:0006113 fermentation P
IMP
SceS000003225
GO:0019655 glucose catabolic process to ethanol P
IMP
SpoSPAC5H10.06c
GO:0034224 cellular response to zinc ion starvation P
IEP
SpoSPAC5H10.06c
GO:0055069 zinc ion homeostasis P
IEP
SpoSPAC5H10.06c
GO:0071276 cellular response to cadmium ion P
IEP
SpoSPAC5H10.06c

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