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Search term: YGR003W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CUL3
SGD link S000003235
Alternative ID YGR003W
Description Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21
Synonyms YGR003W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2166 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cullins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g02980 GI:15218668
Arabidopsis thaliana (Ath) At1g26830 GI:15223361
Arabidopsis thaliana (Ath) At1g43140 GI:15218273
Arabidopsis thaliana (Ath) At1g59790 GI:15218911
Arabidopsis thaliana (Ath) At1g59800 GI:15218925
Arabidopsis thaliana (Ath) At1g69670 GI:15222412
Arabidopsis thaliana (Ath) At4g02570 GI:7484879
Caenorhabditis elegans (Cel) CE11928
(WBGene00000841)
GI:17539492 Q21346
Caenorhabditis elegans (Cel) CE27593
(WBGene00000838)
GI:17566422 Q17391
Caenorhabditis elegans (Cel) CE29089
(WBGene00000836)
GI:17552768 Q17389
Drosophila melanogaster (Dme) 7294516 GI:7294516
Drosophila melanogaster (Dme) 7298217
(FBgn0001980)
GI:17737421
Drosophila melanogaster (Dme) 7304137
(FBgn0015509)
GI:17647593
Homo sapiens (Hsa) Hs22049312 GI:22049312
Homo sapiens (Hsa) Hs22055673 GI:22055673
Homo sapiens (Hsa) Hs4503161 GI:4503161
Homo sapiens (Hsa) Hs4503165
(CUL3)
GI:4503165 Q13618
Saccharomyces cerevisiae (Sce) YDL132w
(S000002290)
GI:6320070 Q12018
Saccharomyces cerevisiae (Sce) YGR003w
(S000003235)
GI:6321440 P53202
Saccharomyces cerevisiae (Sce) YJL047c
(S000003583)
GI:6322414 P47050
Schizosaccharomyces pombe (Spo) SPAC17G6.12 GI:19115171 O13790
Schizosaccharomyces pombe (Spo) SPAC24H6.03 GI:19113861 Q09760
Encephalitozoon cuniculi (Ecu) ECU06g0880 GI:19074338 Q8SRQ4
Encephalitozoon cuniculi (Ecu) ECU07g0860 GI:19074508 Q8SRJ4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IPI
AthAt4g02570
RCA
SceS000003583
TAS
AthAt1g26830
At1g69670
GO:0000152 nuclear ubiquitin ligase complex C
ISS
DmeFBgn0015509
GO:0000794 condensed nuclear chromosome C
IDA
AthAt4g02570
GO:0005634 nucleus C
IDA
AthAt4g02570
SceS000003235
S000003583
GO:0005737 cytoplasm C
IDA
AthAt4g02570
SceS000003235
S000003583
GO:0005819 spindle C
IDA
AthAt4g02570
GO:0005827 polar microtubule C
IDA
HsaCUL3
GO:0005829 cytosol C
IDA
SpoSPAC17G6.12
SPAC24H6.03
GO:0009524 phragmoplast C
IDA
AthAt4g02570
GO:0009941 chloroplast envelope C
IDA
AthAt1g02980
GO:0019005 SCF ubiquitin ligase complex C
IDA
SceS000002290
SpoSPAC17G6.12
IPI
SceS000002290
ISS
AthAt1g02980
SpoSPAC24H6.03
NAS
DmeFBgn0015509
GO:0031463 Cul3-RING ubiquitin ligase complex C
IDA
HsaCUL3
SceS000003235
IMP
SceS000003235
GO:0035361 Cul8-RING ubiquitin ligase complex C
IDA
SceS000003583
GO:0003688 DNA replication origin binding F
IPI
SceS000002290
GO:0004842 ubiquitin-protein ligase activity F
IDA
HsaCUL3
SceS000002290
S000003235
S000003583
ISS
AthAt1g69670
At1g26830
GO:0005515 protein binding F
IPI
AthAt4g02570
At1g69670
At1g26830
CelWBGene00000838
HsaCUL3
SceS000003235
S000003583
GO:0030674 protein binding, bridging F
IMP
SceS000002290
IPI
SceS000002290
GO:0000003 reproduction P
IMP
CelWBGene00000836
GO:0000082 G1/S transition of mitotic cell
cycle
P
IMP
SceS000002290
TAS
HsaCUL3
GO:0000086 G2/M transition of mitotic cell
cycle
P
IGI
SceS000002290
GO:0000090 mitotic anaphase P
IMP
HsaCUL3
GO:0000910 cytokinesis P
IMP
HsaCUL3
GO:0002119 nematode larval development P
IMP
CelWBGene00000836
GO:0006508 proteolysis P
RCA
SceS000002290
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IC
SceS000003235
S000003583
ISS
SceS000003235
TAS
AthAt1g26830
At1g69670
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000836
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00000841
WBGene00000836
GO:0007049 cell cycle P
ISS
AthAt1g69670
At1g26830
At1g02980
At4g02570
GO:0007050 cell cycle arrest P
TAS
HsaCUL3
GO:0007067 mitosis P
IMP
CelWBGene00000836
GO:0007088 regulation of mitosis P
IMP
SceS000003583
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC17G6.12
SPAC24H6.03
GO:0008054 cyclin catabolic process P
IDA
HsaCUL3
GO:0008284 positive regulation of cell proliferation P
TAS
HsaCUL3
GO:0008285 negative regulation of cell proliferation P
IMP
CelWBGene00000836
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000841
WBGene00000838
WBGene00000836
GO:0008361 regulation of cell size P
IMP
CelWBGene00000836
GO:0008629 induction of apoptosis by intracellular
signals
P
TAS
HsaCUL3
GO:0009639 response to red or far red light P
IMP
AthAt1g26830
GO:0009733 response to auxin stimulus P
IMP
AthAt4g02570
GO:0009753 response to jasmonic acid stimulus P
IMP
AthAt4g02570
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00000841
WBGene00000836
WBGene00000838
GO:0009793 embryo development ending in seed
dormancy
P
IGI
AthAt1g69670
At1g26830
IMP
AthAt4g02570
GO:0009867 jasmonic acid mediated signaling
pathway
P
TAS
AthAt4g02570
GO:0009911 positive regulation of flower development P
IMP
AthAt1g26830
GO:0009960 endosperm development P
IGI
AthAt1g26830
At1g69670
GO:0010265 SCF complex assembly P
IPI
AthAt4g02570
GO:0010526 negative regulation of transposition,
RNA-mediated
P
IMP
SceS000003583
GO:0016477 cell migration P
IMP
HsaCUL3
GO:0016567 protein ubiquitination P
IDA
HsaCUL3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent
protein catabolic process
P
IDA
SceS000002290
GO:0031297 replication fork processing P
IMP
SceS000003583
GO:0032876 negative regulation of DNA endoreduplication P
IMP
SpoSPAC17G6.12
GO:0035024 negative regulation of Rho protein signal
transduction
P
IMP
HsaCUL3
GO:0035046 pronuclear migration P
IMP
CelWBGene00000838
GO:0040007 growth P
IMP
CelWBGene00000841
WBGene00000836
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000841
GO:0040015 negative regulation of multicellular organism
growth
P
IMP
CelWBGene00000836
GO:0040025 vulval development P
IMP
CelWBGene00000836
GO:0042752 regulation of circadian rhythm P
IMP
AthAt4g02570
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IC
SpoSPAC17G6.12
SPAC24H6.03
IDA
SceS000002290
IMP
SceS000003235
GO:0043066 negative regulation of apoptosis P
IMP
CelWBGene00000836
GO:0043149 stress fiber assembly P
IMP
HsaCUL3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
IDA
HsaCUL3
GO:0044254 multicellular organismal protein catabolic
process
P
IMP
CelWBGene00000838
GO:0045930 negative regulation of mitotic cell
cycle
P
IMP
CelWBGene00000836
GO:0050790 regulation of catalytic activity P
RCA
SceS000002290
GO:0051049 regulation of transport P
RCA
SceS000002290
GO:0051301 cell division P
IMP
CelWBGene00000836
GO:0051322 anaphase P
IMP
HsaCUL3
GO:0070651 nonfunctional rRNA decay P
IMP
SceS000003583

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68708

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CUL3
(S000003235)
GI:6321440 P53202
Kluyveromyces lactis (Kla) KLLA0C18282g GI:50306105
Eremothecium gossypii (Ego) AGOS_AFR498W GI:45199016