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Search term: YGR024C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name THG1
SGD link S000003256
Alternative ID YGR024C
Description tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes
Synonyms YGR024C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2721 A-DHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g31580 GI:15225104
Arabidopsis thaliana (Ath) At2g32320 GI:15225225
Arabidopsis thaliana (Ath) At2g32330 GI:15225228
Drosophila melanogaster (Dme) 7298195
(FBgn0028925)
GI:19921364
Homo sapiens (Hsa) Hs8923514 GI:8923514
Saccharomyces cerevisiae (Sce) YGR024c
(S000003256)
GI:6321461 P53215
Schizosaccharomyces pombe (Spo) SPCC63.07 GI:19075481 Q9Y7T3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g31580
At2g32320
GO:0005634 nucleus C
IDA
SceS000003256
SpoSPCC63.07
ISS
SpoSPCC63.07
GO:0005737 cytoplasm C
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0005829 cytosol C
IDA
SpoSPCC63.07
GO:0003674 molecular_function F
ND
AthAt2g32320
At2g31580
GO:0008193 tRNA guanylyltransferase activity F
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0006400 tRNA modification P
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0008150 biological_process P
ND
AthAt2g32320
At2g31580

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5959

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) THG1L GI:89242148
Pan troglodytes (Ptr) THG1L GI:114603135
Canis familiaris (Cfa) THG1L GI:57085243
Mus musculus (Mmu) Thg1l
(MGI:1913878)
GI:124377988 Q8BT63
Rattus norvegicus (Rno) Thg1l GI:62078661
Gallus gallus (Gga) THG1L GI:71895317
Drosophila melanogaster (Dme) CG4103
(FBgn0028925)
GI:19921364
Anopheles gambiae (Aga) AgaP_AGAP011752 GI:158300966
Schizosaccharomyces pombe (Spo) SPCC63.07 GI:19075481 Q9Y7T3
Saccharomyces cerevisiae (Sce) THG1
(S000003256)
GI:6321461 P53215
Kluyveromyces lactis (Kla) KLLA0B06237g GI:50303737
Eremothecium gossypii (Ego) AGOS_ABR031C GI:45185260
Neurospora crassa (Ncr) NCU02105.1 GI:32417634
Arabidopsis thaliana (Ath) AT2G32320 GI:186504734
Arabidopsis thaliana (Ath) AT2G31580 GI:42569521
Oryza sativa (Osa) Os05g0535500 GI:115465113
Plasmodium falciparum (Pfa) PF07_0095 GI:124511996


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g31580
At2g32320
MmuMGI:1913878
GO:0005634 nucleus C
IDA
SceS000003256
SpoSPCC63.07
ISS
SpoSPCC63.07
GO:0005737 cytoplasm C
IDA
SceS000003256
ISS
HsaTHG1L
SpoSPCC63.07
GO:0005739 mitochondrion C
IDA
HsaTHG1L
GO:0005829 cytosol C
IDA
SpoSPCC63.07
GO:0003674 molecular_function F
ND
AthAt2g32320
At2g31580
MmuMGI:1913878
GO:0008193 tRNA guanylyltransferase activity F
IDA
SceS000003256
ISS
HsaTHG1L
SpoSPCC63.07
GO:0006400 tRNA modification P
IDA
SceS000003256
ISS
HsaTHG1L
SpoSPCC63.07
GO:0008150 biological_process P
ND
AthAt2g32320
At2g31580
MmuMGI:1913878

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3055

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga8894 ENSANGP00000014165
Ashbya gossypii (Ago) ago622 ABR031C
Arabidopsis thaliana (Ath) ath10157 At2g31580.1
Arabidopsis thaliana (Ath) ath10246 At2g32320.1
Arabidopsis thaliana (Ath) ath10247 At2g32330.1
Candida glabrata (Cgl) cgl3002 CAGL0J00209g
Cryptococcus neoformans (Cne) cne5796 179.m00670
Dictyostelium discoideum (Ddi) ddi10970 DDB0184091
Debaryomyces hansenii (Dha) dha5472 DEHA0F24321g
Drosophila melanogaster (Dme) dme2463 CG4103-PA
(FBgn0028925)
Danio rerio (Dre) dre27393 ENSDARP00000037746
Takifugu rubripes (Fru) fru24344 SINFRUP00000127751
Gallus gallus (Gga) gga5845 ENSGALP00000005900
(THG1L)
Q5ZIR4
Homo sapiens (Hsa) hsa26077 ENSP00000231198
(THG1L)
Q9NWX6
Kluyveromyces lactis (Kla) kla812 KLLA0B06237g
Mus musculus (Mmu) mmu3490 ENSMUSP00000011398
(MGI:1913878)
Q9CY52
Neurospora crassa (Ncr) ncr2047 NCU02105.2
Oryza sativa (Osa) osa14981 2981.m00128
Oryza sativa (Osa) osa77907 7477.m00077
Plasmodium falciparum (Pfa) pfa2425 PF07_0095
Rattus norvegicus (Rno) rno4835 ENSRNOP00000007917
(RGD:1359513)
Q5M965
Saccharomyces cerevisiae (Sce) sce2385 YGR024C
(S000003256)
Schizosaccharomyces pombe (Spo) spo2829 SPCC63.07 Q9Y7T3
Yarrowia lipolytica (Yli) yli4265 YALI0E09823g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g31580
At2g32320
MmuMGI:1913878
GO:0005634 nucleus C
IDA
SceS000003256
SpoSPCC63.07
ISS
SpoSPCC63.07
GO:0005737 cytoplasm C
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0005829 cytosol C
IDA
SpoSPCC63.07
GO:0003674 molecular_function F
ND
AthAt2g32320
At2g31580
MmuMGI:1913878
GO:0008193 tRNA guanylyltransferase activity F
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0006400 tRNA modification P
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0008150 biological_process P
ND
AthAt2g32320
At2g31580
MmuMGI:1913878

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC63.07
(Q9Y7T3)
YGR024C
(S000003256)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003256
SpoSPCC63.07
ISS
SpoSPCC63.07
GO:0005737 cytoplasm C
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0005829 cytosol C
IDA
SpoSPCC63.07
GO:0008193 tRNA guanylyltransferase activity F
IDA
SceS000003256
ISS
SpoSPCC63.07
GO:0006400 tRNA modification P
IDA
SceS000003256
ISS
SpoSPCC63.07

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GO info in one table:

s.khadayate@ucl.ac.uk