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Search term: YGR058W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PEF1
SGD link S000003290
Alternative ID YGR058W
Description Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2
Synonyms YGR058W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0037 ACDHY--

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ca2+-binding protein, EF-Hand protein superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g27480 GI:15225885
Arabidopsis thaliana (Ath) At3g10300 GI:15228249
Arabidopsis thaliana (Ath) At5g04170 GI:15237645
Caenorhabditis elegans (Cel) CE12418
(WBGene00019770)		 GI:17508397
Drosophila melanogaster (Dme) 7289349 GI:7289349
Drosophila melanogaster (Dme) 7303734
(FBgn0033529)		 GI:19921976
Homo sapiens (Hsa) Hs4502565 GI:4502565 P04632
Homo sapiens (Hsa) Hs4507207
(SRI)		 GI:4507207 P30626
Homo sapiens (Hsa) Hs6912388
(GCA)		 GI:6912388 P28676
Homo sapiens (Hsa) Hs6912582
(PEF1)		 GI:6912582 Q9UBV8
Homo sapiens (Hsa) Hs7019485
(PDCD6)		 GI:7019485 O75340
Homo sapiens (Hsa) Hs20544511 GI:20544511
Homo sapiens (Hsa) Hs22048978 GI:22048978
Homo sapiens (Hsa) Hs14161692
(CAPNS2)		 GI:14161692 Q96L46
Saccharomyces cerevisiae (Sce) YGR058w
(S000003290)		 GI:6321495 P53238
Arabidopsis thaliana (Ath) At2g27480 GI:15225885
Arabidopsis thaliana (Ath) At3g10300 GI:15228249
Arabidopsis thaliana (Ath) At5g04170 GI:15237645
Caenorhabditis elegans (Cel) CE12418
(WBGene00019770)		 GI:17508397
Drosophila melanogaster (Dme) 7289349 GI:7289349
Drosophila melanogaster (Dme) 7303734
(FBgn0033529)		 GI:19921976
Homo sapiens (Hsa) Hs4502565 GI:4502565 P04632
Homo sapiens (Hsa) Hs4507207
(SRI)		 GI:4507207 P30626
Homo sapiens (Hsa) Hs6912388
(GCA)		 GI:6912388 P28676
Homo sapiens (Hsa) Hs6912582
(PEF1)		 GI:6912582 Q9UBV8
Homo sapiens (Hsa) Hs7019485
(PDCD6)		 GI:7019485 O75340
Homo sapiens (Hsa) Hs20544511 GI:20544511
Homo sapiens (Hsa) Hs22048978 GI:22048978
Homo sapiens (Hsa) Hs14161692
(CAPNS2)		 GI:14161692 Q96L46
Saccharomyces cerevisiae (Sce) YGR058w
(S000003290)		 GI:6321495 P53238
Arabidopsis thaliana (Ath) At2g27480 GI:15225885
Arabidopsis thaliana (Ath) At3g10300 GI:15228249
Arabidopsis thaliana (Ath) At5g04170 GI:15237645
Caenorhabditis elegans (Cel) CE12418
(WBGene00019770)		 GI:17508397
Drosophila melanogaster (Dme) 7289349 GI:7289349
Drosophila melanogaster (Dme) 7303734
(FBgn0033529)		 GI:19921976
Homo sapiens (Hsa) Hs4502565 GI:4502565 P04632
Homo sapiens (Hsa) Hs4507207
(SRI)		 GI:4507207 P30626
Homo sapiens (Hsa) Hs6912388
(GCA)		 GI:6912388 P28676
Homo sapiens (Hsa) Hs6912582
(PEF1)		 GI:6912582 Q9UBV8
Homo sapiens (Hsa) Hs7019485
(PDCD6)		 GI:7019485 O75340
Homo sapiens (Hsa) Hs20544511 GI:20544511
Homo sapiens (Hsa) Hs22048978 GI:22048978
Homo sapiens (Hsa) Hs14161692
(CAPNS2)		 GI:14161692 Q96L46
Saccharomyces cerevisiae (Sce) YGR058w
(S000003290)		 GI:6321495 P53238


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g27480
At5g04170
At3g10300
GO:0005634 nucleus C
IDA
HsaPDCD6
SceS000003290
GO:0005737 cytoplasm C
IDA
HsaPEF1
SceS000003290
TAS
HsaSRI
GO:0005783 endoplasmic reticulum C
IDA
HsaPDCD6
GO:0005886 plasma membrane C
TAS
HsaGCA
GO:0005935 cellular bud neck C
IDA
SceS000003290
GO:0030427 site of polarized growth C
IDA
SceS000003290
GO:0005102 receptor binding F
TAS
HsaSRI
GO:0005246 calcium channel regulator activity F
TAS
HsaSRI
GO:0005509 calcium ion binding F
IDA
HsaGCA
SceS000003290
ISS
AthAt5g04170
At3g10300
At2g27480
DmeFBgn0033529
HsaPDCD6
GO:0005515 protein binding F
IPI
HsaPEF1
PDCD6
GO:0008270 zinc ion binding F
IDA
SceS000003290
GO:0042803 protein homodimerization activity F
IPI
HsaGCA
GO:0046982 protein heterodimerization activity F
IPI
HsaPEF1
GO:0046983 protein dimerization activity F
IPI
HsaPDCD6
PEF1
GO:0048306 calcium-dependent protein binding F
IPI
HsaPDCD6
GO:0060090 molecular adaptor activity F
IMP
HsaPDCD6
GO:0001508 regulation of action potential P
TAS
HsaSRI
GO:0006810 transport P
TAS
HsaSRI
GO:0006880 intracellular sequestering of iron
ion		 P
TAS
HsaSRI
GO:0006942 regulation of striated muscle contraction P
TAS
HsaSRI
GO:0006944 cellular membrane fusion P
TAS
HsaGCA
GO:0007120 axial cellular bud site selection P
IMP
SceS000003290
GO:0007121 bipolar cellular bud site selection P
IMP
SceS000003290
GO:0007165 signal transduction P
TAS
HsaSRI
GO:0007507 heart development P
TAS
HsaSRI
GO:0007517 muscle organ development P
TAS
HsaSRI
GO:0008016 regulation of heart contraction P
TAS
HsaSRI
GO:0008150 biological_process P
ND
AthAt5g04170
At3g10300
At2g27480
GO:0008624 induction of apoptosis by extracellular
signals		 P
TAS
HsaPDCD6
GO:0051592 response to calcium ion P
IPI
HsaPEF1
ISS
HsaPDCD6

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
7880

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PDCD6 GI:7019485 O75340
Pan troglodytes (Ptr) PDCD6 GI:114598818
Canis familiaris (Cfa) PDCD6 GI:74003143
Mus musculus (Mmu) Pdcd6
(MGI:109283)		 GI:6755000 P12815
Rattus norvegicus (Rno) Pdcd6 GI:34853323
Gallus gallus (Gga) PDCD6 GI:50736185
Drosophila melanogaster (Dme) Alg-2 GI:161076215
Caenorhabditis elegans (Cel) M04F3.4
(CE12418;
WBGene00019770)		 GI:193203051
Saccharomyces cerevisiae (Sce) PEF1
(S000003290)		 GI:6321495 P53238
Kluyveromyces lactis (Kla) KLLA0B08151g GI:50303891
Eremothecium gossypii (Ego) AGOS_AFR570W GI:45199088
Magnaporthe grisea (Mgr) MGG_04818 GI:39945670
Neurospora crassa (Ncr) NCU02738.1 GI:32422989


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeAlg-2
GO:0005625 soluble fraction C
IDA
MmuMGI:109283
GO:0005634 nucleus C
IDA
HsaPDCD6
SceS000003290
GO:0005737 cytoplasm C
IDA
MmuMGI:109283
SceS000003290
GO:0005783 endoplasmic reticulum C
IDA
HsaPDCD6
GO:0005792 microsome C
IDA
MmuMGI:109283
GO:0005935 cellular bud neck C
IDA
SceS000003290
GO:0030427 site of polarized growth C
IDA
SceS000003290
GO:0005509 calcium ion binding F
IDA
SceS000003290
IMP
MmuMGI:109283
ISS
DmeAlg-2
HsaPDCD6
GO:0005515 protein binding F
IPI
HsaPDCD6
MmuMGI:109283
GO:0008270 zinc ion binding F
IDA
SceS000003290
GO:0042803 protein homodimerization activity F
IPI
MmuMGI:109283
GO:0046983 protein dimerization activity F
IPI
HsaPDCD6
MmuMGI:109283
GO:0048306 calcium-dependent protein binding F
IPI
HsaPDCD6
MmuMGI:109283
GO:0060090 molecular adaptor activity F
IMP
HsaPDCD6
GO:0006915 apoptosis P
IDA
MmuMGI:109283
NAS
DmeAlg-2
GO:0006919 activation of caspase activity P
IDA
MmuMGI:109283
GO:0007120 axial cellular bud site selection P
IMP
SceS000003290
GO:0007121 bipolar cellular bud site selection P
IMP
SceS000003290
GO:0008624 induction of apoptosis by extracellular
signals		 P
TAS
HsaPDCD6
GO:0046330 positive regulation of JNK cascade P
IDA
DmeAlg-2
NAS
DmeAlg-2
GO:0051592 response to calcium ion P
IDA
MmuMGI:109283
ISS
HsaPDCD6

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_898

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1721 ENSANGP00000021244
Ashbya gossypii (Ago) ago3762 AFR570W
Arabidopsis thaliana (Ath) ath13120 At3g10300.1
Arabidopsis thaliana (Ath) ath13121 At3g10300.2
Arabidopsis thaliana (Ath) ath13122 At3g10300.3
Arabidopsis thaliana (Ath) ath22584 At5g04170.1
Caenorhabditis elegans (Cel) cel12951 M04F3.4
(CE12418;
WBGene00019770)
Candida glabrata (Cgl) cgl3713 CAGL0K04433g
Cryptococcus neoformans (Cne) cne4495 177.m03344
Cryptococcus neoformans (Cne) cne1826 181.m07795
Dictyostelium discoideum (Ddi) ddi13658 DDB0191092
Dictyostelium discoideum (Ddi) ddi13603 DDB0215364
Debaryomyces hansenii (Dha) dha5849 DEHA0G03454g
Drosophila melanogaster (Dme) dme4326 CG17765-PA
(FBgn0033529)
Drosophila melanogaster (Dme) dme15800 CG40410-PA
Danio rerio (Dre) dre12997 ENSDARP00000009990
(pdcd6)		 Q7T3D5
Danio rerio (Dre) dre27918 ENSDARP00000033243
(zgc:100787)		 Q6DC93
Danio rerio (Dre) dre26656 ENSDARP00000043013
Takifugu rubripes (Fru) fru20304 SINFRUP00000131090
Takifugu rubripes (Fru) fru18393 SINFRUP00000132711
Gallus gallus (Gga) gga12970 ENSGALP00000005083
Gallus gallus (Gga) gga12971 ENSGALP00000005084
(PEF1)
Gallus gallus (Gga) gga10805 ENSGALP00000021816
(PDCD6)
Gallus gallus (Gga) gga10806 ENSGALP00000021817
Homo sapiens (Hsa) hsa733 ENSP00000257133
Homo sapiens (Hsa) hsa24966 ENSP00000264933
(PDCD6)		 O75340
Kluyveromyces lactis (Kla) kla891 KLLA0B08151g
Mus musculus (Mmu) mmu7263 ENSMUSP00000022060
(MGI:109283)		 P12815
Mus musculus (Mmu) mmu18983 ENSMUSP00000030563
(MGI:1915148)		 Q8BFY6
Mus musculus (Mmu) mmu18984 ENSMUSP00000079906
Neurospora crassa (Ncr) ncr2651 NCU02738.2
Oryza sativa (Osa) osa70950 6990.m00203
Oryza sativa (Osa) osa76862 7418.m00152
Rattus norvegicus (Rno) rno24024 ENSRNOP00000018742
(RGD:1359536)		 Q641Z8
Rattus norvegicus (Rno) rno338 ENSRNOP00000019735
(RGD:1311239)		 B5DEP1
Rattus norvegicus (Rno) rno24025 ENSRNOP00000043413
(RGD:1359536)
Rattus norvegicus (Rno) rno24026 ENSRNOP00000048509
Saccharomyces cerevisiae (Sce) sce2425 YGR058W
(S000003290)
Yarrowia lipolytica (Yli) yli1562 YALI0B19712g