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Search term: YGR062C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name COX18
SGD link S000003294
Alternative ID YGR062C
Description Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC
Synonyms YGR062C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1239 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Inner membrane protein translocase involved in respiratory chain assembly

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g24490_2 GI:15221768
Arabidopsis thaliana (Ath) At1g65080 GI:15217841
Arabidopsis thaliana (Ath) At2g28800 GI:15226968
Arabidopsis thaliana (Ath) At2g46470 GI:15225991
Arabidopsis thaliana (Ath) At3g44360 GI:15229946
Arabidopsis thaliana (Ath) At3g44370 GI:15229959
Arabidopsis thaliana (Ath) At5g62050 GI:15241690
Caenorhabditis elegans (Cel) CE07785 GI:17505402
Caenorhabditis elegans (Cel) CE25492 GI:17543670
Drosophila melanogaster (Dme) 7294793 GI:7294793
Drosophila melanogaster (Dme) 7294995 GI:7294995
Homo sapiens (Hsa) Hs22043555 GI:22043555
Homo sapiens (Hsa) Hs4826880 GI:4826880
Saccharomyces cerevisiae (Sce) YER154w
(S000000956)		 GI:6321002 P39952
Saccharomyces cerevisiae (Sce) YGR062c
(S000003294)		 GI:6321499 P53239
Schizosaccharomyces pombe (Spo) SPAC9G1.04 GI:19114471 O14300
Schizosaccharomyces pombe (Spo) SPBC1346.02c GI:19112969
Schizosaccharomyces pombe (Spo) SPCC1442.15c GI:19075829 O94587
Arabidopsis thaliana (Ath) At1g24490_2 GI:15221768
Arabidopsis thaliana (Ath) At1g65080 GI:15217841
Arabidopsis thaliana (Ath) At2g28800 GI:15226968
Arabidopsis thaliana (Ath) At2g46470 GI:15225991
Arabidopsis thaliana (Ath) At3g44360 GI:15229946
Arabidopsis thaliana (Ath) At3g44370 GI:15229959
Arabidopsis thaliana (Ath) At5g62050 GI:15241690
Caenorhabditis elegans (Cel) CE07785 GI:17505402
Caenorhabditis elegans (Cel) CE25492 GI:17543670
Drosophila melanogaster (Dme) 7294793 GI:7294793
Drosophila melanogaster (Dme) 7294995 GI:7294995
Homo sapiens (Hsa) Hs22043555 GI:22043555
Homo sapiens (Hsa) Hs4826880 GI:4826880
Saccharomyces cerevisiae (Sce) YER154w
(S000000956)		 GI:6321002 P39952
Saccharomyces cerevisiae (Sce) YGR062c
(S000003294)		 GI:6321499 P53239
Schizosaccharomyces pombe (Spo) SPAC9G1.04 GI:19114471 O14300
Schizosaccharomyces pombe (Spo) SPBC1346.02c GI:19112969
Schizosaccharomyces pombe (Spo) SPCC1442.15c GI:19075829 O94587


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt5g62050
At3g44370
SceS000000956
SpoSPCC1442.15c
SPAC9G1.04
TAS
AthAt2g46470
GO:0005743 mitochondrial inner membrane C
IDA
AthAt5g62050
SceS000000956
TAS
SpoSPAC9G1.04
GO:0009507 chloroplast C
IDA
AthAt2g28800
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt2g28800
At1g24490
GO:0016020 membrane C
IDA
AthAt2g46470
ISS
AthAt1g65080
At1g24490
GO:0031305 integral to mitochondrial inner
membrane		 C
IDA
SceS000003294
IGI
SpoSPCC1442.15c
GO:0044455 mitochondrial membrane part C
RCA
SceS000000956
GO:0003674 molecular_function F
ND
AthAt2g46470
At1g24490
GO:0008565 protein transporter activity F
ISS
SpoSPAC9G1.04
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
AthAt2g28800
IGI
AthAt5g62050
GO:0032977 membrane insertase activity F
IGI
SceS000003294
SpoSPCC1442.15c
IMP
SceS000003294
S000000956
IPI
SceS000003294
ISS
SceS000003294
GO:0043022 ribosome binding F
IDA
SceS000000956
GO:0006414 translational elongation P
RCA
SceS000003294
GO:0006461 protein complex assembly P
IMP
AthAt5g62050
GO:0006605 protein targeting P
RCA
SceS000000956
GO:0006886 intracellular protein transport P
RCA
SceS000000956
GO:0007165 signal transduction P
ISS
AthAt1g24490
GO:0008535 respiratory chain complex IV assembly P
IGI
SpoSPCC1442.15c
IMP
SpoSPAC9G1.04
GO:0009658 chloroplast organization P
IMP
AthAt1g24490
GO:0010027 thylakoid membrane organization P
IMP
AthAt2g28800
GO:0015031 protein transport P
IGI
SpoSPCC1442.15c
RCA
SceS000000956
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IGI
SceS000003294
IMP
SceS000000956
S000003294
IPI
SceS000003294
S000000956
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000000956
GO:0045038 protein import into chloroplast thylakoid
membrane		 P
IDA
AthAt2g28800
GO:0045039 protein import into mitochondrial inner
membrane		 P
ISS
SpoSPAC9G1.04
TAS
AthAt2g46470
At5g62050
GO:0045184 establishment of protein localization P
RCA
SceS000000956
GO:0051204 protein insertion into mitochondrial
membrane		 P
IGI
SpoSPCC1442.15c
GO:0090342 regulation of cell aging P
IMP
AthAt2g28800

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39094

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) COX18
(S000003294)		 GI:6321499 P53239
Kluyveromyces lactis (Kla) COXT_KLULA GI:50303879
Eremothecium gossypii (Ego) AGOS_AFR575C GI:45199093


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0031305 integral to mitochondrial inner
membrane		 C
IDA
SceS000003294
GO:0032977 membrane insertase activity F
IGI
SceS000003294
IMP
SceS000003294
IPI
SceS000003294
ISS
SceS000003294
GO:0006414 translational elongation P
RCA
SceS000003294
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IGI
SceS000003294
IMP
SceS000003294
IPI
SceS000003294

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20701

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3767 AFR575C
Candida glabrata (Cgl) cgl3717 CAGL0K04521g
Cryptococcus neoformans (Cne) cne5489 179.m00342
Debaryomyces hansenii (Dha) dha6654 DEHA0G21329g
Kluyveromyces lactis (Kla) kla885 KLLA0B08019g
Saccharomyces cerevisiae (Sce) sce2429 YGR062C
(S000003294)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0031305 integral to mitochondrial inner
membrane		 C
IDA
SceS000003294
GO:0032977 membrane insertase activity F
IGI
SceS000003294
IMP
SceS000003294
IPI
SceS000003294
ISS
SceS000003294
GO:0006414 translational elongation P
RCA
SceS000003294
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IGI
SceS000003294
IMP
SceS000003294
IPI
SceS000003294

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1442.15c
(O94587)		 YGR062C
(S000003294)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SpoSPCC1442.15c
GO:0031305 integral to mitochondrial inner
membrane		 C
IDA
SceS000003294
IGI
SpoSPCC1442.15c
GO:0032977 membrane insertase activity F
IGI
SceS000003294
SpoSPCC1442.15c
IMP
SceS000003294
IPI
SceS000003294
ISS
SceS000003294
GO:0006414 translational elongation P
RCA
SceS000003294
GO:0008535 respiratory chain complex IV assembly P
IGI
SpoSPCC1442.15c
GO:0015031 protein transport P
IGI
SpoSPCC1442.15c
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IGI
SceS000003294
IMP
SceS000003294
IPI
SceS000003294
GO:0051204 protein insertion into mitochondrial
membrane		 P
IGI
SpoSPCC1442.15c

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