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Search term: YGR063C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPT4
SGD link S000003295
Alternative ID YGR063C
Description Protein involved in the regulating Pol I and Pol II transcription, pre-mRNA processing, kinetochore function, and gene silencing; forms a complex with Spt5p
Synonyms YGR063C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3490 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Transcription elongation factor SPT4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g63670 GI:10177048
Caenorhabditis elegans (Cel) CE19891
(WBGene00005014)
GI:17554810 Q9TZ93
Drosophila melanogaster (Dme) 7303425 GI:7303425
Homo sapiens (Hsa) Hs4507311
(SUPT4H1)
GI:4507311 P63272
Saccharomyces cerevisiae (Sce) YGR063c
(S000003295)
GI:6321501 P32914
Schizosaccharomyces pombe (Spo) SPBC21C3.16c GI:19113388 Q9P7K8
Encephalitozoon cuniculi (Ecu) ECU08g1660 GI:19173491 Q8SR92


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003295
GO:0000784 nuclear chromosome, telomeric region C
IDA
SceS000003295
GO:0000790 nuclear chromatin C
IC
SpoSPBC21C3.16c
GO:0005634 nucleus C
IDA
HsaSUPT4H1
SpoSPBC21C3.16c
IPI
SceS000003295
GO:0005654 nucleoplasm C
EXP
HsaSUPT4H1
GO:0005829 cytosol C
IDA
SpoSPBC21C3.16c
GO:0008023 transcription elongation factor
complex
C
IPI
SceS000003295
GO:0032044 DSIF complex C
IDA
SpoSPBC21C3.16c
IPI
SceS000003295
GO:0033553 rDNA heterochromatin C
IDA
SceS000003295
GO:0003700 transcription factor activity F
TAS
HsaSUPT4H1
GO:0003701 RNA polymerase I transcription factor
activity
F
IPI
SceS000003295
GO:0005515 protein binding F
IPI
HsaSUPT4H1
SpoSPBC21C3.16c
GO:0008148 negative transcription elongation factor
activity
F
IDA
HsaSUPT4H1
GO:0008159 positive transcription elongation factor
activity
F
IDA
HsaSUPT4H1
GO:0008270 zinc ion binding F
ISS
SpoSPBC21C3.16c
GO:0016944 RNA polymerase II transcription elongation factor
activity
F
IGI
SpoSPBC21C3.16c
IMP
SceS000003295
ISS
SceS000003295
GO:0046982 protein heterodimerization activity F
IPI
HsaSUPT4H1
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
IDA
HsaSUPT4H1
GO:0006283 transcription-coupled nucleotide-excision
repair
P
IGI
SceS000003295
GO:0006325 chromatin organization P
TAS
SceS000003295
GO:0006338 chromatin remodeling P
ISS
SpoSPBC21C3.16c
TAS
HsaSUPT4H1
GO:0006342 chromatin silencing P
IMP
SceS000003295
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003295
ISS
SceS000003295
TAS
HsaSUPT4H1
GO:0006356 regulation of transcription from RNA polymerase I
promoter
P
IMP
SceS000003295
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
TAS
HsaSUPT4H1
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
IDA
HsaSUPT4H1
IPI
SceS000003295
GO:0006397 mRNA processing P
IPI
SpoSPBC21C3.16c
GO:0007059 chromosome segregation P
IMP
SceS000003295
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00005014
GO:0034244 negative regulation of RNA elongation from RNA
polymerase II promoter
P
IGI
SpoSPBC21C3.16c
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IDA
HsaSUPT4H1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39095

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SPT4
(S000003295)
GI:6321501 P32914
Kluyveromyces lactis (Kla) SPT4_KLULA GI:50303877
Eremothecium gossypii (Ego) AGOS_AFR576C GI:45199094


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003295
GO:0000784 nuclear chromosome, telomeric region C
IDA
SceS000003295
GO:0005634 nucleus C
IPI
SceS000003295
GO:0008023 transcription elongation factor
complex
C
IPI
SceS000003295
GO:0032044 DSIF complex C
IPI
SceS000003295
GO:0033553 rDNA heterochromatin C
IDA
SceS000003295
GO:0003701 RNA polymerase I transcription factor
activity
F
IPI
SceS000003295
GO:0016944 RNA polymerase II transcription elongation factor
activity
F
IMP
SceS000003295
ISS
SceS000003295
GO:0006283 transcription-coupled nucleotide-excision
repair
P
IGI
SceS000003295
GO:0006325 chromatin organization P
TAS
SceS000003295
GO:0006342 chromatin silencing P
IMP
SceS000003295
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003295
ISS
SceS000003295
GO:0006356 regulation of transcription from RNA polymerase I
promoter
P
IMP
SceS000003295
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
IPI
SceS000003295
GO:0007059 chromosome segregation P
IMP
SceS000003295

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2500

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga841 ENSANGP00000014073
Ashbya gossypii (Ago) ago3768 AFR576C
Arabidopsis thaliana (Ath) ath23081 At5g08565.1
Arabidopsis thaliana (Ath) ath28489 At5g63670.1
Caenorhabditis elegans (Cel) cel10155 F54C4.2
(CE19891;
WBGene00005014)
Candida glabrata (Cgl) cgl3718 CAGL0K04543g
Cryptococcus neoformans (Cne) cne322 162.m02897
Dictyostelium discoideum (Ddi) ddi9945 DDB0186435
Debaryomyces hansenii (Dha) dha6655 DEHA0G21351g
Drosophila melanogaster (Dme) dme4740 CG12372-PA
(FBgn0028683)
Danio rerio (Dre) dre26198 ENSDARP00000048842
(zgc:92824)
Q6DGQ0
Encephalitozoon cuniculi (Ecu) ecu322 19173491
Takifugu rubripes (Fru) fru23817 SINFRUP00000138917
Gallus gallus (Gga) gga8639 ENSGALP00000001391
Gallus gallus (Gga) gga8640 ENSGALP00000001392
(SUPT4H1)
Homo sapiens (Hsa) hsa14063 ENSP00000225504
(SUPT4H1)
P63272
Kluyveromyces lactis (Kla) kla884 KLLA0B07997g
Mus musculus (Mmu) mmu4517 ENSMUSP00000020780
Neurospora crassa (Ncr) ncr3728 NCU03838.2
Oryza sativa (Osa) osa38534 5062.m00141
Plasmodium falciparum (Pfa) pfa511 PF10_0293
Rattus norvegicus (Rno) rno5832 ENSRNOP00000010448
(RGD:1306372)
B5DEM7
Saccharomyces cerevisiae (Sce) sce2430 YGR063C
(S000003295)
Schizosaccharomyces pombe (Spo) spo4668 SPBC21C3.16c Q9P7K8


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003295
GO:0000784 nuclear chromosome, telomeric region C
IDA
SceS000003295
GO:0000790 nuclear chromatin C
IC
SpoSPBC21C3.16c
GO:0005634 nucleus C
IDA
SpoSPBC21C3.16c
IPI
SceS000003295
ISS
DmeFBgn0028683
GO:0005829 cytosol C
IDA
SpoSPBC21C3.16c
GO:0008023 transcription elongation factor
complex
C
IPI
SceS000003295
GO:0032044 DSIF complex C
IDA
SpoSPBC21C3.16c
IPI
SceS000003295
GO:0033553 rDNA heterochromatin C
IDA
SceS000003295
GO:0003682 chromatin binding F
ISS
DmeFBgn0028683
PfaPF10_0293
GO:0003700 transcription factor activity F
ISS
PfaPF10_0293
GO:0003701 RNA polymerase I transcription factor
activity
F
IPI
SceS000003295
GO:0005515 protein binding F
IPI
SpoSPBC21C3.16c
GO:0008270 zinc ion binding F
ISS
SpoSPBC21C3.16c
GO:0016944 RNA polymerase II transcription elongation factor
activity
F
IGI
SpoSPBC21C3.16c
IMP
SceS000003295
ISS
SceS000003295
GO:0006283 transcription-coupled nucleotide-excision
repair
P
IGI
SceS000003295
GO:0006325 chromatin organization P
TAS
SceS000003295
GO:0006338 chromatin remodeling P
ISS
SpoSPBC21C3.16c
GO:0006342 chromatin silencing P
IMP
SceS000003295
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003295
ISS
SceS000003295
GO:0006356 regulation of transcription from RNA polymerase I
promoter
P
IMP
SceS000003295
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
IPI
SceS000003295
GO:0006397 mRNA processing P
IPI
SpoSPBC21C3.16c
GO:0007059 chromosome segregation P
IMP
SceS000003295
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00005014
GO:0016582 non-covalent chromatin modification P
ISS
DmeFBgn0028683
GO:0034244 negative regulation of RNA elongation from RNA
polymerase II promoter
P
IGI
SpoSPBC21C3.16c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC21C3.16c
(Q9P7K8)
YGR063C
(S000003295)