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Search term: YGR065C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VHT1
SGD link S000003297
Alternative ID YGR065C
Description High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin
Synonyms YGR065C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2533 ACDHYP-

KOGs classification KOGs description
METABOLISM Permease of the major facilitator superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g30560 GI:15221441
Arabidopsis thaliana (Ath) At2g13100 GI:15224962
Arabidopsis thaliana (Ath) At3g47420 GI:7487305
Arabidopsis thaliana (Ath) At4g17550 GI:15236559
Arabidopsis thaliana (Ath) At4g25220 GI:15234973
Caenorhabditis elegans (Cel) CE06428 GI:17542314
Caenorhabditis elegans (Cel) CE06429
(WBGene00011718)		 GI:17542316 Q22410
Caenorhabditis elegans (Cel) CE06430 GI:17542318
Caenorhabditis elegans (Cel) CE10650
(WBGene00009811)		 GI:17561094 Q20523
Caenorhabditis elegans (Cel) CE16381
(WBGene00011688)		 GI:17564202 O62376
Caenorhabditis elegans (Cel) CE23965 GI:17564204 O62376
Caenorhabditis elegans (Cel) CE29223
(WBGene00016593)		 GI:17539138 A3QMC7
Drosophila melanogaster (Dme) 7291274 GI:7291274
Homo sapiens (Hsa) Hs14150047 GI:14150047 Q8NCC5
Homo sapiens (Hsa) Hs20558703 GI:20558703
Homo sapiens (Hsa) Hs21361600 GI:11095363 P57057
Homo sapiens (Hsa) Hs4503847
(SLC37A4)		 GI:4503847 O43826
Homo sapiens (Hsa) HsM9507121 GI:9507121
Saccharomyces cerevisiae (Sce) YAL067c
(S000000062)		 GI:6319250 P39709
Saccharomyces cerevisiae (Sce) YCR028c
(S000000623)		 GI:6319876 P25621
Saccharomyces cerevisiae (Sce) YGR065c
(S000003297)		 GI:6321502 P53241
Saccharomyces cerevisiae (Sce) YGR260w
(S000003492)		 GI:6321698 P53322
Saccharomyces cerevisiae (Sce) YIL166c GI:6322025 P40445
Saccharomyces cerevisiae (Sce) YJR152w
(S000003913)		 GI:6322612 P15365
Saccharomyces cerevisiae (Sce) YLL055w
(S000003978)		 GI:6322973 Q12235
Saccharomyces cerevisiae (Sce) YLR004c
(S000003994)		 GI:6323032 Q07904
Saccharomyces cerevisiae (Sce) YOL162w GI:6324411 Q08330
Saccharomyces cerevisiae (Sce) YOL163w GI:6324410 Q08337
Schizosaccharomyces pombe (Spo) SPAC1002.16c GI:19114416 Q9US44
Schizosaccharomyces pombe (Spo) SPAC1039.04 GI:19115907 Q9US37
Schizosaccharomyces pombe (Spo) SPAC11D3.18c GI:19113725 Q10097
Schizosaccharomyces pombe (Spo) SPAC1B3.15c GI:19115712 O13879
Schizosaccharomyces pombe (Spo) SPAC1B3.16c GI:19115713 O13880
Schizosaccharomyces pombe (Spo) SPBC1683.12 GI:19111860 Q9P6J0
Schizosaccharomyces pombe (Spo) SPBC1773.15 GI:19111922 O94572
Schizosaccharomyces pombe (Spo) SPBC2G2.01c GI:19113222 O43000
Schizosaccharomyces pombe (Spo) SPBPB10D8.01 GI:19111837 Q9C0V8
Schizosaccharomyces pombe (Spo) SPCC417.10 GI:19075787 O94491
Schizosaccharomyces pombe (Spo) SPCC757.13 GI:19075188 O74923
Schizosaccharomyces pombe (Spo) SPCPB1C11.03 GI:19075926 Q9C0U9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003492
GO:0005783 endoplasmic reticulum C
IDA
SceS000003978
S000003994
SpoSPAC1039.04
SPAC11D3.18c
SPBC1683.12
SPBPB10D8.01
SPCC417.10
SPCC757.13
SPCPB1C11.03
NAS
HsaSLC37A4
GO:0005789 endoplasmic reticulum membrane C
EXP
HsaSLC37A4
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1002.16c
SPAC1B3.15c
SPAC1B3.16c
SPBC1773.15
SPBC2G2.01c
SPCC417.10
GO:0005886 plasma membrane C
IDA
AthAt4g17550
SceS000003297
IGI
SceS000000623
IMP
SceS000003913
ISS
SceS000000623
S000003913
GO:0005887 integral to plasma membrane C
ISS
SceS000003492
SpoSPAC11D3.18c
SPBC1683.12
SPAC1039.04
SPAC1002.16c
SPAC1B3.15c
TAS
SpoSPAC1B3.16c
SPBC2G2.01c
GO:0016020 membrane C
ISS
SceS000000062
YIL166c
YOL162w
YOL163w
GO:0016021 integral to membrane C
ISS
SceS000003994
NAS
HsaSLC37A4
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IDA
HsaSLC37A4
GO:0032153 cell division site C
IDA
SpoSPAC1002.16c
SPBC1773.15
SPCC417.10
GO:0051286 cell tip C
IDA
SpoSPAC1002.16c
SPBC1773.15
SPCC417.10
GO:0005215 transporter activity F
ISS
AthAt4g25220
At1g30560
SceS000000062
YIL166c
S000003994
YOL163w
YOL162w
NAS
HsaSLC37A4
GO:0005351 sugar:hydrogen symporter activity F
ISS
AthAt4g17550
At2g13100
At3g47420
GO:0015075 ion transmembrane transporter activity F
ISS
SceS000003978
GO:0015124 allantoate transmembrane transporter
activity		 F
IMP
SceS000003913
ISS
SceS000003913
GO:0015152 glucose-6-phosphate transmembrane transporter
activity		 F
EXP
HsaSLC37A4
IDA
HsaSLC37A4
IMP
HsaSLC37A4
GO:0015169 glycerol-3-phosphate transmembrane transporter
activity		 F
ISS
AthAt1g30560
GO:0015225 biotin transporter activity F
IDA
SceS000003297
IGI
SpoSPAC1B3.16c
ISS
SpoSPAC1B3.15c
GO:0015233 pantothenate transporter activity F
IDA
SpoSPBC2G2.01c
IGI
SceS000000623
IMP
SceS000000623
GO:0015663 nicotinamide mononucleotide transmembrane
transporter activity		 F
IEP
SceS000003492
IMP
SceS000003492
ISS
SpoSPAC11D3.18c
SPAC1039.04
SPAC1002.16c
SPBC1683.12
GO:0022857 transmembrane transporter activity F
ISS
SpoSPBC1773.15
SPCC417.10
SPCC757.13
RCA
SceS000003297
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000003297
GO:0033229 cysteine transmembrane transporter
activity		 F
IDA
SceS000003978
IMP
SceS000003978
ISS
SpoSPBPB10D8.01
SPCPB1C11.03
GO:0042936 dipeptide transporter activity F
IGI
SceS000003913
IMP
SceS000003913
GO:0003333 amino acid transmembrane transport P
ISS
SpoSPBPB10D8.01
SPCPB1C11.03
GO:0006006 glucose metabolic process P
NAS
HsaSLC37A4
GO:0006633 fatty acid biosynthetic process P
IMP
SpoSPBC2G2.01c
GO:0006810 transport P
ISS
AthAt1g30560
At4g25220
SceS000000062
YIL166c
YOL162w
S000003994
YOL163w
SpoSPCC417.10
NAS
HsaSLC37A4
GO:0006897 endocytosis P
IMP
SceS000000623
GO:0007088 regulation of mitosis P
IGI
SpoSPBC2G2.01c
GO:0008643 carbohydrate transport P
ISS
AthAt2g13100
At4g17550
At3g47420
GO:0015719 allantoate transport P
IMP
SceS000003913
GO:0015760 glucose-6-phosphate transport P
IDA
HsaSLC37A4
IMP
HsaSLC37A4
GO:0015794 glycerol-3-phosphate transport P
ISS
AthAt1g30560
GO:0015878 biotin transport P
IDA
SceS000003297
IGI
SpoSPAC1B3.16c
ISS
SpoSPAC1B3.15c
GO:0015887 pantothenate transmembrane transport P
IDA
SpoSPBC2G2.01c
IGI
SceS000000623
IMP
SceS000000623
GO:0015890 nicotinamide mononucleotide transport P
IEP
SceS000003492
IMP
SceS000003492
ISS
SpoSPAC11D3.18c
SPAC1039.04
SPAC1002.16c
SPBC1683.12
GO:0035353 nicotinamide mononucleotide transmembrane
transport		 P
ISS
SpoSPAC1002.16c
SPAC1039.04
SPAC11D3.18c
SPBC1683.12
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009811
GO:0042593 glucose homeostasis P
IDA
HsaSLC37A4
GO:0042883 cysteine transport P
IDA
SceS000003978
IMP
SceS000003978
ISS
SpoSPBPB10D8.01
SPCPB1C11.03
GO:0042938 dipeptide transport P
IGI
SceS000003913
IMP
SceS000003913
GO:0051181 cofactor transport P
IGI
SpoSPAC1B3.16c
RCA
SceS000003297
GO:0055085 transmembrane transport P
ISS
SpoSPBC1773.15
SPCC757.13

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48726

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) VHT1
(S000003297)		 GI:6321502 P53241
Kluyveromyces lactis (Kla) KLLA0B07953g GI:50303873


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000003297
GO:0015225 biotin transporter activity F
IDA
SceS000003297
GO:0022857 transmembrane transporter activity F
RCA
SceS000003297
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000003297
GO:0015878 biotin transport P
IDA
SceS000003297
GO:0051181 cofactor transport P
RCA
SceS000003297

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31511

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3770 AFR578C
Candida glabrata (Cgl) cgl3721 CAGL0K04609g
Kluyveromyces lactis (Kla) kla882 KLLA0B07953g
Saccharomyces cerevisiae (Sce) sce2432 YGR065C
(S000003297)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000003297
GO:0015225 biotin transporter activity F
IDA
SceS000003297
GO:0022857 transmembrane transporter activity F
RCA
SceS000003297
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000003297
GO:0015878 biotin transport P
IDA
SceS000003297
GO:0051181 cofactor transport P
RCA
SceS000003297

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1B3.16c
(O13880)		 YGR065C
(S000003297)
SPAC1B3.15c
(O13879)		 YGR065C
(S000003297)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1B3.15c
SPAC1B3.16c
GO:0005886 plasma membrane C
IDA
SceS000003297
GO:0005887 integral to plasma membrane C
ISS
SpoSPAC1B3.15c
TAS
SpoSPAC1B3.16c
GO:0015225 biotin transporter activity F
IDA
SceS000003297
IGI
SpoSPAC1B3.16c
ISS
SpoSPAC1B3.15c
GO:0022857 transmembrane transporter activity F
RCA
SceS000003297
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000003297
GO:0015878 biotin transport P
IDA
SceS000003297
IGI
SpoSPAC1B3.16c
ISS
SpoSPAC1B3.15c
GO:0051181 cofactor transport P
IGI
SpoSPAC1B3.16c
RCA
SceS000003297

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