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Search term: YGR070W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ROM1
SGD link S000003302
Alternative ID YGR070W
Description GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP
Synonyms YGR070W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4305 --DHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING RhoGEF GTPase

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7292538 GI:7292538
Homo sapiens (Hsa) Hs11128045_2 GI:11128045
Homo sapiens (Hsa) Hs19923327 GI:19923327 Q7Z628
Homo sapiens (Hsa) Hs22060844 GI:22060844
Homo sapiens (Hsa) Hs4504797_2 GI:4504797
Homo sapiens (Hsa) Hs9506401 GI:9506401 Q9NR81
Saccharomyces cerevisiae (Sce) YGR070w
(S000003302)
GI:6321507 P53046
Saccharomyces cerevisiae (Sce) YLR371w
(S000004363)
GI:6323403 P51862
Saccharomyces cerevisiae (Sce) YLR425w
(S000004417)
GI:6323457 Q06412
Schizosaccharomyces pombe (Spo) SPAC1006.06 GI:19115765 Q9UTR5
Schizosaccharomyces pombe (Spo) SPCC645.06c GI:19075615 Q9Y7U5
Schizosaccharomyces pombe (Spo) SPCC645.07 GI:19075616 Q9Y7U6
Encephalitozoon cuniculi (Ecu) ECU03g0550 GI:19173015 Q8SW55


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000935 barrier septum C
IDA
SpoSPAC1006.06
SPCC645.07
GO:0005575 cellular_component C
ND
SceS000004417
GO:0005622 intracellular C
TAS
SceS000003302
GO:0005634 nucleus C
IDA
SpoSPCC645.07
GO:0005829 cytosol C
IDA
SpoSPAC1006.06
SPCC645.06c
GO:0005934 cellular bud tip C
TAS
SceS000004363
GO:0005935 cellular bud neck C
RCA
SceS000004363
GO:0030428 cell septum C
IDA
SpoSPCC645.07
GO:0032153 cell division site C
IDA
SpoSPCC645.06c
GO:0051285 cell cortex of cell tip C
IDA
SpoSPAC1006.06
SPCC645.07
GO:0051286 cell tip C
IDA
SpoSPCC645.07
GO:0004871 signal transducer activity F
RCA
SceS000004363
TAS
SceS000003302
GO:0005089 Rho guanyl-nucleotide exchange factor
activity
F
IDA
SceS000004363
S000004417
IGI
SpoSPAC1006.06
SPCC645.07
SPCC645.06c
IPI
SceS000004363
ISA
SceS000003302
GO:0005515 protein binding F
IPI
SpoSPAC1006.06
SPCC645.07
SPCC645.06c
GO:0005546 phosphatidylinositol-4,5-bisphosphate
binding
F
IDA
SceS000004363
GO:0060089 molecular transducer activity F
RCA
SceS000004363
GO:0000003 reproduction P
RCA
SceS000004363
GO:0000918 selection of site for barrier septum
formation
P
IMP
SpoSPAC1006.06
GO:0006950 response to stress P
IMP
SceS000004363
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000004363
GO:0007015 actin filament organization P
TAS
SceS000003302
S000004363
GO:0007047 cellular cell wall organization P
RCA
SceS000004417
S000004363
GO:0007117 budding cell bud growth P
TAS
SceS000003302
S000004363
GO:0007165 signal transduction P
IGI
SceS000004417
IMP
SceS000004417
GO:0007264 small GTPase mediated signal transduction P
TAS
SceS000003302
S000004363
GO:0008360 regulation of cell shape P
IGI
SpoSPCC645.07
GO:0009272 fungal-type cell wall biogenesis P
IGI
SpoSPCC645.07
SPAC1006.06
GO:0009966 regulation of signal transduction P
RCA
SceS000004363
GO:0010590 regulation of cytokinetic cell
separation
P
IMP
SpoSPCC645.06c
GO:0030010 establishment of cell polarity P
TAS
SceS000003302
S000004363
GO:0030994 primary cell septum disassembly P
IMP
SpoSPCC645.06c
GO:0031505 fungal-type cell wall organization P
IGI
SceS000004417
IMP
SceS000004417
TAS
SceS000003302
S000004363
GO:0032319 regulation of Rho GTPase activity P
IC
SpoSPCC645.06c
SPAC1006.06
IGI
SpoSPCC645.07
GO:0032953 regulation of 1,3-beta-glucan biosynthetic
process
P
IGI
SpoSPCC645.07
IMP
SpoSPCC645.06c
GO:0035023 regulation of Rho protein signal
transduction
P
IGI
SpoSPCC645.06c
SPAC1006.06
GO:0035025 positive regulation of Rho protein signal
transduction
P
IGI
SpoSPCC645.07
GO:0045807 positive regulation of endocytosis P
IMP
SceS000004363
GO:0051049 regulation of transport P
RCA
SceS000004363
GO:0051301 cell division P
RCA
SceS000004363
GO:0051666 actin cortical patch localization P
IMP
SpoSPAC1006.06
SPCC645.07
SPCC645.06c
GO:0060624 regulation of ascospore wall 1,3-beta-glucan
biosynthetic process
P
IC
SpoSPCC645.06c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3066

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga7741 ENSANGP00000019609
Caenorhabditis elegans (Cel) cel6191 F13E6.6
(CE39724;
WBGene00006468)
Drosophila melanogaster (Dme) dme5573 CG9635-PA
(FBgn0023172)
Drosophila melanogaster (Dme) dme5574 CG9635-PD
(FBgn0023172)
Drosophila melanogaster (Dme) dme5575 CG9635-PE
(FBgn0023172)
Drosophila melanogaster (Dme) dme5576 CG9635-PF
(FBgn0023172)
Danio rerio (Dre) dre4847 ENSDARP00000026889
(LOC568069)
Danio rerio (Dre) dre22856 ENSDARP00000041654
Danio rerio (Dre) dre17049 ENSDARP00000045588
Danio rerio (Dre) dre9489 ENSDARP00000047621
Takifugu rubripes (Fru) fru2652 SINFRUP00000140762
Takifugu rubripes (Fru) fru2653 SINFRUP00000140763
Takifugu rubripes (Fru) fru22237 SINFRUP00000157218
Gallus gallus (Gga) gga13199 ENSGALP00000010764
Gallus gallus (Gga) gga13198 ENSGALP00000010766
(ARHGEF12)
Gallus gallus (Gga) gga26276 ENSGALP00000021624
(ARHGEF11)
Gallus gallus (Gga) gga26275 ENSGALP00000021625
Homo sapiens (Hsa) hsa2317 ENSP00000313470
(ARHGEF11)
A6NFK4
Homo sapiens (Hsa) hsa6699 ENSP00000349056
(ARHGEF12)
Q9NZN5-2
Homo sapiens (Hsa) hsa6700 ENSP00000349567
Homo sapiens (Hsa) hsa2318 ENSP00000354644
(ARHGEF11)
O15085
Homo sapiens (Hsa) hsa2319 ENSP00000355112
Mus musculus (Mmu) mmu27454 ENSMUSP00000079802
Rattus norvegicus (Rno) rno28422 ENSRNOP00000012043
(RGD:1305111)
Q5BMA6
Rattus norvegicus (Rno) rno16337 ENSRNOP00000020717
(RGD:619705)
Rattus norvegicus (Rno) rno16338 ENSRNOP00000039684
(RGD:619705)
Saccharomyces cerevisiae (Sce) sce2438 YGR070W
(S000003302)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000003302
GO:0005826 actomyosin contractile ring C
IDA
DmeFBgn0023172
GO:0016324 apical plasma membrane C
IDA
DmeFBgn0023172
GO:0016328 lateral plasma membrane C
IDA
DmeFBgn0023172
GO:0030478 actin cap C
IDA
DmeFBgn0023172
GO:0045177 apical part of cell C
IDA
DmeFBgn0023172
GO:0045178 basal part of cell C
IDA
DmeFBgn0023172
GO:0045179 apical cortex C
IDA
DmeFBgn0023172
GO:0004871 signal transducer activity F
TAS
SceS000003302
GO:0005089 Rho guanyl-nucleotide exchange factor
activity
F
ISA
SceS000003302
ISS
DmeFBgn0023172
NAS
DmeFBgn0023172
TAS
DmeFBgn0023172
GO:0019992 diacylglycerol binding F
ISS
DmeFBgn0023172
GO:0007015 actin filament organization P
IMP
DmeFBgn0023172
TAS
SceS000003302
GO:0007117 budding cell bud growth P
TAS
SceS000003302
GO:0007264 small GTPase mediated signal transduction P
TAS
SceS000003302
GO:0007277 pole cell development P
IMP
DmeFBgn0023172
GO:0007349 cellularization P
IMP
DmeFBgn0023172
GO:0007369 gastrulation P
TAS
DmeFBgn0023172
GO:0007370 ventral furrow formation P
IMP
DmeFBgn0023172
GO:0007374 posterior midgut invagination P
IMP
DmeFBgn0023172
GO:0007375 anterior midgut invagination P
IMP
DmeFBgn0023172
GO:0007377 germ-band extension P
IMP
DmeFBgn0023172