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Search term: YGR072W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UPF3
SGD link S000003304
Alternative ID YGR072W
Description Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons; involved in telomere maintenance
Synonyms YGR072W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1295 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Nonsense-mediated decay protein Upf3

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g33980 GI:15218461
Caenorhabditis elegans (Cel) CE26973 GI:17563280
Drosophila melanogaster (Dme) 7291669 GI:7291669
Homo sapiens (Hsa) Hs12711674 GI:12711674 Q9BZI7
Homo sapiens (Hsa) Hs12711676
(UPF3A)		 GI:12711676 Q9H1J1
Homo sapiens (Hsa) Hs18375525 GI:18375525 Q9H1J1
Homo sapiens (Hsa) Hs18375528
(UPF3B)		 GI:18375528 Q9BZI7
Saccharomyces cerevisiae (Sce) YGR072w
(S000003304)		 GI:6321509 P48412
Schizosaccharomyces pombe (Spo) SPAC13G7.03 GI:19114617 Q10267


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g33980
GO:0005634 nucleus C
IDA
SceS000003304
ISS
SpoSPAC13G7.03
NAS
HsaUPF3A
GO:0005730 nucleolus C
IDA
SpoSPAC13G7.03
GO:0005737 cytoplasm C
ISS
SpoSPAC13G7.03
NAS
HsaUPF3A
TAS
SceS000003304
GO:0005844 polysome C
IDA
SceS000003304
GO:0003674 molecular_function F
ND
SceS000003304
SpoSPAC13G7.03
GO:0005487 nucleocytoplasmic transporter activity F
NAS
HsaUPF3A
GO:0005515 protein binding F
IPI
HsaUPF3A
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IMP
AthAt1g33980
ISS
SpoSPAC13G7.03
NAS
HsaUPF3A
TAS
SceS000003304
GO:0016567 protein ubiquitination P
IMP
SceS000003304
IPI
SceS000003304
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003304

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39098

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) UPF3
(S000003304)		 GI:6321509 P48412
Kluyveromyces lactis (Kla) KLLA0D03718g GI:50306513
Eremothecium gossypii (Ego) AGOS_AER204W GI:45190807


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003304
GO:0005737 cytoplasm C
TAS
SceS000003304
GO:0005844 polysome C
IDA
SceS000003304
GO:0003674 molecular_function F
ND
SceS000003304
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
TAS
SceS000003304
GO:0016567 protein ubiquitination P
IMP
SceS000003304
IPI
SceS000003304
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003304

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1639

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2096 ENSANGP00000011347
Ashbya gossypii (Ago) ago2706 AER204W
Arabidopsis thaliana (Ath) ath3542 At1g33980.1
Caenorhabditis elegans (Cel) cel9327 F46B6.3a
Caenorhabditis elegans (Cel) cel9328 F46B6.3b
(CE30440)
Candida glabrata (Cgl) cgl3576 CAGL0K01309g
Debaryomyces hansenii (Dha) dha1199 DEHA0B12034g
Drosophila melanogaster (Dme) dme6857 CG11184-PB
(FBgn0034923)
Drosophila melanogaster (Dme) dme6858 CG11184-PC
(FBgn0034923)
Danio rerio (Dre) dre5727 ENSDARP00000011948
(upf3b)		 Q7SXF0
Takifugu rubripes (Fru) fru13575 SINFRUP00000129031
Takifugu rubripes (Fru) fru13574 SINFRUP00000129034
Takifugu rubripes (Fru) fru31147 SINFRUP00000139367
Gallus gallus (Gga) gga17135 ENSGALP00000014025
Gallus gallus (Gga) gga17136 ENSGALP00000014026
Gallus gallus (Gga) gga17137 ENSGALP00000014027
Gallus gallus (Gga) gga11167 ENSGALP00000024902
Gallus gallus (Gga) gga2656 ENSGALP00000027095
Gallus gallus (Gga) gga2657 ENSGALP00000027096
(UPF3A)
Homo sapiens (Hsa) hsa33313 ENSP00000245418
(UPF3B)		 Q9BZI7-2
Homo sapiens (Hsa) hsa33314 ENSP00000276201
(UPF3B)		 Q9BZI7-1
Homo sapiens (Hsa) hsa9099 ENSP00000306623
Homo sapiens (Hsa) hsa9100 ENSP00000329592
(UPF3A)		 Q9H1J1-2
Kluyveromyces lactis (Kla) kla2229 KLLA0D03718g
Mus musculus (Mmu) mmu28839 ENSMUSP00000035926
Mus musculus (Mmu) mmu25660 ENSMUSP00000037354
(MGI:1914281)		 Q3ULJ3
Mus musculus (Mmu) mmu28840 ENSMUSP00000075614
(MGI:1915384)		 Q3ULL6
Neurospora crassa (Ncr) ncr3330 NCU03435.2
Oryza sativa (Osa) osa42753 5420.m00117
Oryza sativa (Osa) osa42761 5420.m00142
Plasmodium falciparum (Pfa) pfa4345 PF13_0158
Rattus norvegicus (Rno) rno30704 ENSRNOP00000008669
Rattus norvegicus (Rno) rno12751 ENSRNOP00000023552
(RGD:1308778)
Rattus norvegicus (Rno) rno30703 ENSRNOP00000029696
(RGD:1560264)
Rattus norvegicus (Rno) rno30702 ENSRNOP00000045317
Saccharomyces cerevisiae (Sce) sce2440 YGR072W
(S000003304)
Schizosaccharomyces pombe (Spo) spo1717 SPAC13G7.03 Q10267


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g33980
GO:0005634 nucleus C
IDA
SceS000003304
ISO
MmuMGI:1915384
MGI:1914281
ISS
SpoSPAC13G7.03
GO:0005730 nucleolus C
IDA
SpoSPAC13G7.03
GO:0005737 cytoplasm C
ISS
SpoSPAC13G7.03
TAS
SceS000003304
GO:0005844 polysome C
IDA
SceS000003304
GO:0003674 molecular_function F
ND
SceS000003304
SpoSPAC13G7.03
GO:0003729 mRNA binding F
ISO
MmuMGI:1915384
MGI:1914281
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IMP
AthAt1g33980
DmeFBgn0034923
ISS
SpoSPAC13G7.03
TAS
SceS000003304
GO:0006986 response to unfolded protein P
ISO
MmuMGI:1914281
MGI:1915384
GO:0016567 protein ubiquitination P
IMP
SceS000003304
IPI
SceS000003304
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003304

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC13G7.03
(Q10267)		 YGR072W
(S000003304)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003304
ISS
SpoSPAC13G7.03
GO:0005730 nucleolus C
IDA
SpoSPAC13G7.03
GO:0005737 cytoplasm C
ISS
SpoSPAC13G7.03
TAS
SceS000003304
GO:0005844 polysome C
IDA
SceS000003304
GO:0003674 molecular_function F
ND
SceS000003304
SpoSPAC13G7.03
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
ISS
SpoSPAC13G7.03
TAS
SceS000003304
GO:0016567 protein ubiquitination P
IMP
SceS000003304
IPI
SceS000003304
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000003304

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