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Search term: YGR075C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRP38
SGD link S000003307
Alternative ID YGR075C
Description Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly
Synonyms YGR075C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39100

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PRP38
(S000003307)		 GI:6321512
Kluyveromyces lactis (Kla) KLLA0D03795g GI:50306521
Eremothecium gossypii (Ego) AGOS_AER206C GI:45190809


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000003307
IMP
SceS000003307
GO:0003674 molecular_function F
ND
SceS000003307
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000003307
GO:0006414 translational elongation P
RCA
SceS000003307

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31601

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2708 AER206C
Candida glabrata (Cgl) cgl3574 CAGL0K01265g
Kluyveromyces lactis (Kla) kla2233 KLLA0D03795g
Saccharomyces cerevisiae (Sce) sce2443 YGR075C
(S000003307)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000003307
IMP
SceS000003307
GO:0003674 molecular_function F
ND
SceS000003307
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000003307
GO:0006414 translational elongation P
RCA
SceS000003307

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC19C2.08
(Q9UUD2)		 YGR075C
(S000003307)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC19C2.08
GO:0005829 cytosol C
IDA
SpoSPBC19C2.08
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000003307
IMP
SceS000003307
ISS
SpoSPBC19C2.08
GO:0003674 molecular_function F
ND
SceS000003307
SpoSPBC19C2.08
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000003307
GO:0000398 nuclear mRNA splicing, via spliceosome P
ISS
SpoSPBC19C2.08
GO:0006414 translational elongation P
RCA
SceS000003307

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