Bahler Lab

Search term: YGR094W

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name VAS1

SGD link S000003326

Alternative ID YGR094W

Description Mitochondrial and cytoplasmic valyl-tRNA synthetase

Synonyms YGR094W

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0432 ACDHYPE

KOGs classification KOGs description

INFORMATION STORAGE AND PROCESSING Valyl-tRNA synthetase

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005622 intracellular C
NAS
Hsa VARS

GO:0005737 cytoplasm C
IDA
Spo SPBC1709.02c
IMP
Sce S000003326

GO:0005739 mitochondrion C
IDA
Ath At1g14610
Sce S000003326
Spo SPAC4A8.08c
IMP
Sce S000003326

GO:0005829 cytosol C
EXP
Hsa VARS
IDA
Spo SPBC1709.02c

GO:0009507 chloroplast C
IDA
Ath At5g16710
At1g14610

GO:0009570 chloroplast stroma C
IDA
Ath At5g16710

GO:0009941 chloroplast envelope C
IDA
Ath At5g16710

GO:0004812 aminoacyl-tRNA ligase activity F
ISS
Ath At1g14610

GO:0004818 glutamate-tRNA ligase activity F
ISS
Dme FBgn0027079

GO:0004832 valine-tRNA ligase activity F
EXP
Hsa VARS
IDA
Hsa VARS
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c
ISS
Dme FBgn0027079
Sce S000003326

GO:0005515 protein binding F
IPI
Hsa VARS

GO:0005524 ATP binding F
ISS
Ath At1g14610
Spo SPAC4A8.08c
SPBC1709.02c

GO:0045174 glutathione dehydrogenase (ascorbate)
activity F
IDA
Ath At5g16710
ISS
Ath At5g16710

GO:0000003 reproduction P
IMP
Cel WBGene00006936

GO:0002119 nematode larval development P
IMP
Cel WBGene00006936

GO:0006414 translational elongation P
NAS
Hsa VARS

GO:0006417 regulation of translation P
RCA
Sce S000003326

GO:0006418 tRNA aminoacylation for protein
translation P
ISS
Ath At1g14610

GO:0006438 valyl-tRNA aminoacylation P
IDA
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c
ISS
Dme FBgn0027079

GO:0006898 receptor-mediated endocytosis P
IMP
Cel WBGene00006936

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00006936

GO:0009793 embryo development ending in seed
dormancy P
IMP
Ath At1g14610

GO:0010731 protein amino acid glutathionylation P
IDA
Ath At5g16710

GO:0018996 molting cycle, collagen and cuticulin-based
cuticle P
IMP
Cel WBGene00006936

GO:0032543 mitochondrial translation P
IC
Spo SPAC4A8.08c

GO:0040007 growth P
IMP
Cel WBGene00006936

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00006936

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00006936

GO:0040035 hermaphrodite genitalia development P
IMP
Cel WBGene00006936

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

4587

Species Gene ID NCBI link UniProt link

Homo sapiens (Hsa) VARS GI:5454158 P26640

Pan troglodytes (Ptr) VARS GI:114606509

Canis familiaris (Cfa) VARS GI:73972294

Mus musculus (Mmu) Vars
(MGI:90675) GI:34328204 Q3TII4

Drosophila melanogaster (Dme) Aats-val
(FBgn0027079) GI:17864482 Q0E993

Anopheles gambiae (Aga) AgaP_AGAP010420 GI:158289903

Caenorhabditis elegans (Cel) vrs-2
(CE24685;
WBGene00006936) GI:17510661 Q9U1Q4

Schizosaccharomyces pombe (Spo) vas2
(SPAP27G11.06c) GI:19112227 Q9P7N2

Saccharomyces cerevisiae (Sce) VAS1
(S000003326) GI:6321531 P07806

Kluyveromyces lactis (Kla) KLLA0D14971g GI:50307489

Eremothecium gossypii (Ego) AGOS_AAR034W GI:45184857

Magnaporthe grisea (Mgr) MGG_04396 GI:145603153

Neurospora crassa (Ncr) NCU01965.1 GI:32417354

Arabidopsis thaliana (Ath) TWN2 GI:15223829

Oryza sativa (Osa) Os03g0694900 GI:115454745

Oryza sativa (Osa) Os10g0506200 GI:115482838

Plasmodium falciparum (Pfa) PF14_0589 GI:124810112

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Pfa PF14_0589

GO:0005622 intracellular C
NAS
Hsa VARS

GO:0005634 nucleus C
IDA
Spo SPAP27G11.06c

GO:0005737 cytoplasm C
IMP
Sce S000003326

GO:0005739 mitochondrion C
IDA
Ath TWN2
Mmu MGI:90675
Sce S000003326
IMP
Sce S000003326

GO:0005768 endosome C
IDA
Spo SPAP27G11.06c

GO:0005794 Golgi apparatus C
IDA
Spo SPAP27G11.06c

GO:0005829 cytosol C
EXP
Hsa VARS
IDA
Spo SPAP27G11.06c

GO:0009507 chloroplast C
IDA
Ath TWN2

GO:0030121 AP-1 adaptor complex C
IDA
Spo SPAP27G11.06c

GO:0004812 aminoacyl-tRNA ligase activity F
ISS
Ath TWN2

GO:0004818 glutamate-tRNA ligase activity F
ISS
Dme FBgn0027079

GO:0004832 valine-tRNA ligase activity F
EXP
Hsa VARS
IDA
Hsa VARS
Sce S000003326
ISO
Mmu MGI:90675
ISS
Dme FBgn0027079
Sce S000003326

GO:0005515 protein binding F
IPI
Hsa VARS

GO:0005524 ATP binding F
ISS
Ath TWN2

GO:0030276 clathrin binding F
ISS
Spo SPAP27G11.06c

GO:0000003 reproduction P
IMP
Cel WBGene00006936

GO:0002119 nematode larval development P
IMP
Cel WBGene00006936

GO:0006414 translational elongation P
NAS
Hsa VARS

GO:0006417 regulation of translation P
RCA
Sce S000003326

GO:0006418 tRNA aminoacylation for protein
translation P
ISS
Ath TWN2

GO:0006438 valyl-tRNA aminoacylation P
IDA
Sce S000003326
ISS
Dme FBgn0027079

GO:0006886 intracellular protein transport P
IC
Spo SPAP27G11.06c

GO:0006898 receptor-mediated endocytosis P
IMP
Cel WBGene00006936

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00006936

GO:0009793 embryo development ending in seed
dormancy P
IMP
Ath TWN2

GO:0016192 vesicle-mediated transport P
IMP
Spo SPAP27G11.06c

GO:0016197 endosome transport P
IMP
Spo SPAP27G11.06c

GO:0018996 molting cycle, collagen and cuticulin-based
cuticle P
IMP
Cel WBGene00006936

GO:0040007 growth P
IMP
Cel WBGene00006936

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00006936

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00006936

GO:0040035 hermaphrodite genitalia development P
IMP
Cel WBGene00006936

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_199

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Pfa PF14_0589

GO:0005737 cytoplasm C
IDA
Spo SPBC1709.02c
IMP
Sce S000003326

GO:0005739 mitochondrion C
IDA
Ath At1g14610
Mmu MGI:1916165
Sce S000003326
Spo SPAC4A8.08c
IMP
Sce S000003326

GO:0005829 cytosol C
IDA
Spo SPBC1709.02c

GO:0009507 chloroplast C
IDA
Ath At1g14610
At5g16715

GO:0009570 chloroplast stroma C
IDA
Ath At5g16715

GO:0003674 molecular_function F
ND
Mmu MGI:1916165

GO:0004812 aminoacyl-tRNA ligase activity F
ISS
Ath At1g14610
At5g16715

GO:0004818 glutamate-tRNA ligase activity F
ISS
Dme FBgn0027079

GO:0004832 valine-tRNA ligase activity F
IDA
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c
ISS
Dme FBgn0027079
FBgn0035942
Sce S000003326

GO:0005524 ATP binding F
ISS
Ath At1g14610
At5g16715
Spo SPAC4A8.08c
SPBC1709.02c

GO:0000003 reproduction P
IMP
Cel WBGene00006936
WBGene00006935

GO:0002119 nematode larval development P
IMP
Cel WBGene00006936
WBGene00006935

GO:0006417 regulation of translation P
RCA
Sce S000003326

GO:0006418 tRNA aminoacylation for protein
translation P
ISS
Ath At1g14610
At5g16715

GO:0006438 valyl-tRNA aminoacylation P
IDA
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c
ISS
Dme FBgn0027079

GO:0006898 receptor-mediated endocytosis P
IMP
Cel WBGene00006936
WBGene00006935

GO:0008150 biological_process P
ND
Mmu MGI:1916165

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00006936
WBGene00006935

GO:0009793 embryo development ending in seed
dormancy P
IMP
Ath At1g14610
At5g16715
NAS
Ath At5g16715

GO:0018996 molting cycle, collagen and cuticulin-based
cuticle P
IMP
Cel WBGene00006936

GO:0032543 mitochondrial translation P
IC
Spo SPAC4A8.08c

GO:0040007 growth P
IMP
Cel WBGene00006936
WBGene00006935

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00006936
WBGene00006935

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00006936

GO:0040035 hermaphrodite genitalia development P
IMP
Cel WBGene00006936

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPAC4A8.08c
(O14160) YGR094W
(S000003326)

SPBC1709.02c
(O75005) YGR094W
(S000003326)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005737 cytoplasm C
IDA
Spo SPBC1709.02c
IMP
Sce S000003326

GO:0005739 mitochondrion C
IDA
Sce S000003326
Spo SPAC4A8.08c
IMP
Sce S000003326

GO:0005829 cytosol C
IDA
Spo SPBC1709.02c

GO:0004832 valine-tRNA ligase activity F
IDA
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c
ISS
Sce S000003326

GO:0005524 ATP binding F
ISS
Spo SPAC4A8.08c
SPBC1709.02c

GO:0006417 regulation of translation P
RCA
Sce S000003326

GO:0006438 valyl-tRNA aminoacylation P
IDA
Sce S000003326
Spo SPAC4A8.08c
SPBC1709.02c

GO:0032543 mitochondrial translation P
IC
Spo SPAC4A8.08c

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YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0432	ACDHYPE

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSING	Valyl-tRNA synthetase

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g14610	GI:15223829
Arabidopsis thaliana (Ath)	At1g27160	GI:15223442
Arabidopsis thaliana (Ath)	At5g16710_2	GI:11271417
Caenorhabditis elegans (Cel)	CE07611	GI:17566738
Caenorhabditis elegans (Cel)	CE24685 (WBGene00006936)	GI:17510661	Q9U1Q4
Drosophila melanogaster (Dme)	7295018	GI:7295018
Drosophila melanogaster (Dme)	7303353 (FBgn0027079)	GI:17864482	Q0E993
Homo sapiens (Hsa)	Hs22056512	GI:22056512
Homo sapiens (Hsa)	Hs22056721	GI:20555624
Homo sapiens (Hsa)	Hs22059965	GI:22059965
Homo sapiens (Hsa)	Hs5454158_2 (VARS)	GI:5454158	P26640
Saccharomyces cerevisiae (Sce)	YGR094w (S000003326)	GI:6321531	P07806
Schizosaccharomyces pombe (Spo)	SPAC4A8.08c	GI:19114731	O14160
Schizosaccharomyces pombe (Spo)	SPBC1709.02c	GI:19112227	O75005
Encephalitozoon cuniculi (Ecu)	ECU04g1140	GI:19074192	Q8SS27
Arabidopsis thaliana (Ath)	At1g14610	GI:15223829
Arabidopsis thaliana (Ath)	At1g27160	GI:15223442
Arabidopsis thaliana (Ath)	At5g16710_2	GI:11271417
Caenorhabditis elegans (Cel)	CE07611	GI:17566738
Caenorhabditis elegans (Cel)	CE24685 (WBGene00006936)	GI:17510661	Q9U1Q4
Drosophila melanogaster (Dme)	7295018	GI:7295018
Drosophila melanogaster (Dme)	7303353 (FBgn0027079)	GI:17864482	Q0E993
Homo sapiens (Hsa)	Hs22056512	GI:22056512
Homo sapiens (Hsa)	Hs22056721	GI:20555624
Homo sapiens (Hsa)	Hs22059965	GI:22059965
Homo sapiens (Hsa)	Hs5454158_2 (VARS)	GI:5454158	P26640
Saccharomyces cerevisiae (Sce)	YGR094w (S000003326)	GI:6321531	P07806
Schizosaccharomyces pombe (Spo)	SPAC4A8.08c	GI:19114731	O14160
Schizosaccharomyces pombe (Spo)	SPBC1709.02c	GI:19112227	O75005
Encephalitozoon cuniculi (Ecu)	ECU04g1140	GI:19074192	Q8SS27
Arabidopsis thaliana (Ath)	At1g14610	GI:15223829
Arabidopsis thaliana (Ath)	At1g27160	GI:15223442
Arabidopsis thaliana (Ath)	At5g16710_2	GI:11271417
Caenorhabditis elegans (Cel)	CE07611	GI:17566738
Caenorhabditis elegans (Cel)	CE24685 (WBGene00006936)	GI:17510661	Q9U1Q4
Drosophila melanogaster (Dme)	7295018	GI:7295018
Drosophila melanogaster (Dme)	7303353 (FBgn0027079)	GI:17864482	Q0E993
Homo sapiens (Hsa)	Hs22056512	GI:22056512
Homo sapiens (Hsa)	Hs22056721	GI:20555624
Homo sapiens (Hsa)	Hs22059965	GI:22059965
Homo sapiens (Hsa)	Hs5454158_2 (VARS)	GI:5454158	P26640
Saccharomyces cerevisiae (Sce)	YGR094w (S000003326)	GI:6321531	P07806
Schizosaccharomyces pombe (Spo)	SPAC4A8.08c	GI:19114731	O14160
Schizosaccharomyces pombe (Spo)	SPBC1709.02c	GI:19112227	O75005
Encephalitozoon cuniculi (Ecu)	ECU04g1140	GI:19074192	Q8SS27

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	VARS	GI:5454158	P26640
Pan troglodytes (Ptr)	VARS	GI:114606509
Canis familiaris (Cfa)	VARS	GI:73972294
Mus musculus (Mmu)	Vars (MGI:90675)	GI:34328204	Q3TII4
Drosophila melanogaster (Dme)	Aats-val (FBgn0027079)	GI:17864482	Q0E993
Anopheles gambiae (Aga)	AgaP_AGAP010420	GI:158289903
Caenorhabditis elegans (Cel)	vrs-2 (CE24685; WBGene00006936)	GI:17510661	Q9U1Q4
Schizosaccharomyces pombe (Spo)	vas2 (SPAP27G11.06c)	GI:19112227	Q9P7N2
Saccharomyces cerevisiae (Sce)	VAS1 (S000003326)	GI:6321531	P07806
Kluyveromyces lactis (Kla)	KLLA0D14971g	GI:50307489
Eremothecium gossypii (Ego)	AGOS_AAR034W	GI:45184857
Magnaporthe grisea (Mgr)	MGG_04396	GI:145603153
Neurospora crassa (Ncr)	NCU01965.1	GI:32417354
Arabidopsis thaliana (Ath)	TWN2	GI:15223829
Oryza sativa (Osa)	Os03g0694900	GI:115454745
Oryza sativa (Osa)	Os10g0506200	GI:115482838
Plasmodium falciparum (Pfa)	PF14_0589	GI:124810112

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga7338	ENSANGP00000010240
Anopheles gambiae (Aga)	aga2070	ENSANGP00000011461
Anopheles gambiae (Aga)	aga2069	ENSANGP00000029272
Anopheles gambiae (Aga)	aga7339	ENSANGP00000029618
Ashbya gossypii (Ago)	ago220	AAR034W
Arabidopsis thaliana (Ath)	ath1545	At1g14610.1
Arabidopsis thaliana (Ath)	ath23900	At5g16715.1
Caenorhabditis elegans (Cel)	cel21015	Y87G2A.5 (CE24685; WBGene00006936)
Caenorhabditis elegans (Cel)	cel21429	ZC513.4 (CE36065; WBGene00006935)
Candida glabrata (Cgl)	cgl1758	CAGL0G03091g
Cryptococcus neoformans (Cne)	cne4745	186.m03611
Dictyostelium discoideum (Ddi)	ddi12785	DDB0231269
Dictyostelium discoideum (Ddi)	ddi12832	DDB0231274
Debaryomyces hansenii (Dha)	dha1805	DEHA0C08525g
Drosophila melanogaster (Dme)	dme4849	CG4062-PA (FBgn0027079)
Drosophila melanogaster (Dme)	dme4848	CG4062-PB (FBgn0027079)
Drosophila melanogaster (Dme)	dme8662	CG5660-PA (FBgn0035942)
Danio rerio (Dre)	dre10097	ENSDARP00000009115
Danio rerio (Dre)	dre2837	ENSDARP00000019062
Danio rerio (Dre)	dre10103	ENSDARP00000028041
Danio rerio (Dre)	dre10098	ENSDARP00000040217
Danio rerio (Dre)	dre10100	ENSDARP00000043534
Danio rerio (Dre)	dre10099	ENSDARP00000044488 (LOC563785)
Danio rerio (Dre)	dre10101	ENSDARP00000048952
Danio rerio (Dre)	dre10102	ENSDARP00000049866
Escherichia coli (Eco)	eco4100	16132080
Encephalitozoon cuniculi (Ecu)	ecu830	19074192
Takifugu rubripes (Fru)	fru26143	SINFRUP00000141774
Takifugu rubripes (Fru)	fru26146	SINFRUP00000141776
Takifugu rubripes (Fru)	fru1845	SINFRUP00000151814
Takifugu rubripes (Fru)	fru26145	SINFRUP00000169983
Takifugu rubripes (Fru)	fru26144	SINFRUP00000174023
Homo sapiens (Hsa)	hsa26855	ENSP00000211402 (VARS)	P26640
Homo sapiens (Hsa)	hsa26781	ENSP00000316092 (VARS2)
Kluyveromyces lactis (Kla)	kla2723	KLLA0D14971g
Mus musculus (Mmu)	mmu11522	ENSMUSP00000007244
Mus musculus (Mmu)	mmu11574	ENSMUSP00000047917 (MGI:1916165)	Q3U2A8
Neurospora crassa (Ncr)	ncr1910	NCU01965.2
Oryza sativa (Osa)	osa4003	2082.m00080
Oryza sativa (Osa)	osa42669	5200.m00213
Oryza sativa (Osa)	osa56452	6191.m00119
Oryza sativa (Osa)	osa59540	6353.m00043
Oryza sativa (Osa)	osa62662	6679.m00161
Oryza sativa (Osa)	osa62704	6679.m00189
Oryza sativa (Osa)	osa69523	6966.m00111
Oryza sativa (Osa)	osa70876	6989.m00153
Oryza sativa (Osa)	osa85157	8372.m00035
Plasmodium falciparum (Pfa)	pfa1344	PF14_0589
Rattus norvegicus (Rno)	rno17390	ENSRNOP00000001105
Rattus norvegicus (Rno)	rno17447	ENSRNOP00000001160 (RGD:3950)	Q04462
Rattus norvegicus (Rno)	rno17389	ENSRNOP00000046565 (RGD:1303122)	Q6MG21
Saccharomyces cerevisiae (Sce)	sce2462	YGR094W (S000003326)
Schizosaccharomyces pombe (Spo)	spo1457	SPAC4A8.08c	O14160
Schizosaccharomyces pombe (Spo)	spo2741	SPBC1709.02c	O75005
Yarrowia lipolytica (Yli)	yli6191	YALI0F20218g

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC4A8.08c (O14160)	YGR094W (S000003326)
SPBC1709.02c (O75005)	YGR094W (S000003326)