YOGY Home YOGY Help

Search term: YGR095C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RRP46
SGD link S000003327
Alternative ID YGR095C
Description Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp46p (EXOSC5)
Synonyms YGR095C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1069 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Exosomal 3'-5' exoribonuclease complex, subunit Rrp46

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g46210 GI:15231368
Caenorhabditis elegans (Cel) CE02146
(WBGene00000798)		 GI:17531759 Q17952
Drosophila melanogaster (Dme) 7299337 GI:7299337
Homo sapiens (Hsa) Hs9910360 GI:9910360
Saccharomyces cerevisiae (Sce) YGR095c
(S000003327)		 GI:6321532
Schizosaccharomyces pombe (Spo) SPBC115.01c GI:19112052 O42894
Encephalitozoon cuniculi (Ecu) ECU10g0270 GI:19074636 Q8SR73
Arabidopsis thaliana (Ath) At3g46210 GI:15231368
Caenorhabditis elegans (Cel) CE02146
(WBGene00000798)		 GI:17531759 Q17952
Drosophila melanogaster (Dme) 7299337 GI:7299337
Homo sapiens (Hsa) Hs9910360 GI:9910360
Saccharomyces cerevisiae (Sce) YGR095c
(S000003327)		 GI:6321532
Schizosaccharomyces pombe (Spo) SPBC115.01c GI:19112052 O42894
Encephalitozoon cuniculi (Ecu) ECU10g0270 GI:19074636 Q8SR73


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000003327
ISS
SpoSPBC115.01c
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000003327
ISS
SpoSPBC115.01c
GO:0000178 exosome (RNase complex) C
TAS
CelWBGene00000798
GO:0005575 cellular_component C
ND
AthAt3g46210
GO:0005634 nucleus C
IDA
SpoSPBC115.01c
GO:0005730 nucleolus C
RCA
SceS000003327
GO:0005829 cytosol C
IDA
SpoSPBC115.01c
GO:0000175 3'-5'-exoribonuclease activity F
ISS
AthAt3g46210
SpoSPBC115.01c
GO:0003674 molecular_function F
ND
SceS000003327
GO:0003723 RNA binding F
ISS
AthAt3g46210
SpoSPBC115.01c
GO:0008408 3'-5' exonuclease activity F
ISS
CelWBGene00000798
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000003327
GO:0002119 nematode larval development P
IMP
CelWBGene00000798
GO:0006309 DNA fragmentation involved in apoptotic nuclear
change		 P
IGI
CelWBGene00000798
IMP
CelWBGene00000798
GO:0006364 rRNA processing P
ISS
SpoSPBC115.01c
GO:0006396 RNA processing P
ISS
AthAt3g46210
TAS
CelWBGene00000798
GO:0006402 mRNA catabolic process P
ISS
SpoSPBC115.01c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000798
GO:0016180 snRNA processing P
RCA
SceS000003327
GO:0031126 snoRNA 3'-end processing P
RCA
SceS000003327
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000003327
GO:0034472 snRNA 3'-end processing P
RCA
SceS000003327
GO:0034475 U4 snRNA 3'-end processing P
RCA
SceS000003327
GO:0040007 growth P
IMP
CelWBGene00000798
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000798
GO:0043144 snoRNA processing P
RCA
SceS000003327
GO:0043628 ncRNA 3'-end processing P
IC
SceS000003327
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000003327
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000003327
GO:0070651 nonfunctional rRNA decay P
IC
SceS000003327
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000003327
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000003327
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000003327
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000003327

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5981

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EXOSC5 GI:47174864
Pan troglodytes (Ptr) EXOSC5 GI:114677471
Canis familiaris (Cfa) EXOSC5 GI:73947485
Mus musculus (Mmu) Exosc5
(MGI:107889)		 GI:20070392 Q3U2K4
Rattus norvegicus (Rno) Exosc5 GI:62639177
Drosophila melanogaster (Dme) Rrp46
(FBgn0037815)		 GI:24645688
Anopheles gambiae (Aga) AgaP_AGAP002177 GI:158284969
Caenorhabditis elegans (Cel) crn-5
(CE02146;
WBGene00000798)		 GI:17531759 Q17952
Saccharomyces cerevisiae (Sce) RRP46
(S000003327)		 GI:37362654
Kluyveromyces lactis (Kla) KLLA0D14993g GI:50307491
Eremothecium gossypii (Ego) AGOS_AAR035C GI:45184858
Magnaporthe grisea (Mgr) MGG_09936 GI:39965336
Neurospora crassa (Ncr) NCU03268.1 GI:32420521
Arabidopsis thaliana (Ath) AT3G46210 GI:79314404
Oryza sativa (Osa) Os03g0854200 GI:115456671


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000003327
IPI
DmeFBgn0037815
ISS
DmeFBgn0037815
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000003327
ISS
DmeFBgn0037815
GO:0000178 exosome (RNase complex) C
TAS
CelWBGene00000798
GO:0005575 cellular_component C
ND
AthAt3g46210
MmuMGI:107889
GO:0005730 nucleolus C
NAS
HsaEXOSC5
RCA
SceS000003327
GO:0005737 cytoplasm C
IDA
DmeFBgn0037815
NAS
HsaEXOSC5
GO:0000175 3'-5'-exoribonuclease activity F
ISS
AthAt3g46210
DmeFBgn0037815
NAS
HsaEXOSC5
GO:0003674 molecular_function F
ND
MmuMGI:107889
SceS000003327
GO:0003723 RNA binding F
ISS
AthAt3g46210
GO:0005515 protein binding F
IPI
HsaEXOSC5
GO:0008408 3'-5' exonuclease activity F
ISS
CelWBGene00000798
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000003327
GO:0002119 nematode larval development P
IMP
CelWBGene00000798
GO:0006309 DNA fragmentation involved in apoptotic nuclear
change		 P
IGI
CelWBGene00000798
IMP
CelWBGene00000798
GO:0006364 rRNA processing P
NAS
HsaEXOSC5
GO:0006396 RNA processing P
ISS
AthAt3g46210
TAS
CelWBGene00000798
GO:0006397 mRNA processing P
ISS
DmeFBgn0037815
GO:0008150 biological_process P
ND
MmuMGI:107889
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000798
GO:0016180 snRNA processing P
RCA
SceS000003327
GO:0031126 snoRNA 3'-end processing P
RCA
SceS000003327
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000003327
GO:0034472 snRNA 3'-end processing P
RCA
SceS000003327
GO:0034475 U4 snRNA 3'-end processing P
RCA
SceS000003327
GO:0040007 growth P
IMP
CelWBGene00000798
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000798
GO:0043144 snoRNA processing P
RCA
SceS000003327
GO:0043628 ncRNA 3'-end processing P
IC
SceS000003327
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000003327
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000003327
GO:0070651 nonfunctional rRNA decay P
IC
SceS000003327
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000003327
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000003327
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000003327
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000003327

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3406

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4307 ENSANGP00000019439
Ashbya gossypii (Ago) ago221 AAR035C
Arabidopsis thaliana (Ath) ath15901 At3g46210.1
Caenorhabditis elegans (Cel) cel1931 C14A4.5
(CE02146;
WBGene00000798)
Candida glabrata (Cgl) cgl1759 CAGL0G03113g
Cryptococcus neoformans (Cne) cne810 163.m04820
Dictyostelium discoideum (Ddi) ddi7606 DDB0185805
Debaryomyces hansenii (Dha) dha1807 DEHA0C08569g
Drosophila melanogaster (Dme) dme11895 CG4043-PA
(FBgn0037815)
Danio rerio (Dre) dre9447 ENSDARP00000048607
Danio rerio (Dre) dre30050 ENSDARP00000049619
Encephalitozoon cuniculi (Ecu) ecu552 19074636
Takifugu rubripes (Fru) fru8036 SINFRUP00000156655
Homo sapiens (Hsa) hsa16453 ENSP00000221233
(EXOSC5)		 Q9NQT4
Kluyveromyces lactis (Kla) kla2724 KLLA0D14993g
Mus musculus (Mmu) mmu23401 ENSMUSP00000078580
(MGI:107889)		 Q9CRA8
Neurospora crassa (Ncr) ncr3166 NCU03268.2
Oryza sativa (Osa) osa64281 6703.m00194
Rattus norvegicus (Rno) rno1317 ENSRNOP00000028026
(RGD:1307861)		 B2RZ47
Saccharomyces cerevisiae (Sce) sce2463 YGR095C
(S000003327)
Schizosaccharomyces pombe (Spo) spo3726 SPBC115.01c O42894
Yarrowia lipolytica (Yli) yli6192 YALI0F20240g