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Search term: YGR096W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TPC1
SGD link S000003328
Alternative ID YGR096W
Description Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family
Synonyms YGR096W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0752 ACDHYP-

KOGs classification KOGs description
METABOLISM Mitochondrial solute carrier protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14560 GI:15223820
Arabidopsis thaliana (Ath) At1g78180 GI:15218236
Arabidopsis thaliana (Ath) At2g37890 GI:15224395
Arabidopsis thaliana (Ath) At3g20240 GI:15231083
Arabidopsis thaliana (Ath) At3g21390 GI:15232548
Arabidopsis thaliana (Ath) At3g51870 GI:15231063
Arabidopsis thaliana (Ath) At3g53940 GI:15232378
Arabidopsis thaliana (Ath) At3g55640 GI:15228163
Arabidopsis thaliana (Ath) At4g01100 GI:15234063
Arabidopsis thaliana (Ath) At4g26180 GI:15236140
Arabidopsis thaliana (Ath) At4g32400 GI:15236783
Arabidopsis thaliana (Ath) At5g01500 GI:15240999
Arabidopsis thaliana (Ath) At5g48970 GI:15239754
Arabidopsis thaliana (Ath) At5g64970 GI:15238315
Caenorhabditis elegans (Cel) CE10358
(WBGene00009666)		 GI:17507311 Q93717
Caenorhabditis elegans (Cel) CE29222
(WBGene00016588)		 GI:17539126 A3QMB9
Drosophila melanogaster (Dme) 7291871 GI:20130387
Drosophila melanogaster (Dme) 7299384 GI:7299384
Drosophila melanogaster (Dme) 7300625 GI:7300625
Homo sapiens (Hsa) Hs11119432 GI:11119432
Homo sapiens (Hsa) Hs15011910 GI:15011910
Homo sapiens (Hsa) Hs20548100 GI:20548100
Homo sapiens (Hsa) Hs21687151 GI:18044568 Q9BR35
Homo sapiens (Hsa) Hs22053628 GI:20988432 P16260
Saccharomyces cerevisiae (Sce) YGR096w
(S000003328)		 GI:6321533 P53257
Saccharomyces cerevisiae (Sce) YHR002w
(S000001044)		 GI:6321789 P38702
Saccharomyces cerevisiae (Sce) YPR011c GI:6325268 Q12251
Schizosaccharomyces pombe (Spo) SPAC17H9.08 GI:19114490 O13805
Schizosaccharomyces pombe (Spo) SPBC1604.04 GI:19113428 O94370
Arabidopsis thaliana (Ath) At1g14560 GI:15223820
Arabidopsis thaliana (Ath) At1g78180 GI:15218236
Arabidopsis thaliana (Ath) At2g37890 GI:15224395
Arabidopsis thaliana (Ath) At3g20240 GI:15231083
Arabidopsis thaliana (Ath) At3g21390 GI:15232548
Arabidopsis thaliana (Ath) At3g51870 GI:15231063
Arabidopsis thaliana (Ath) At3g53940 GI:15232378
Arabidopsis thaliana (Ath) At3g55640 GI:15228163
Arabidopsis thaliana (Ath) At4g01100 GI:15234063
Arabidopsis thaliana (Ath) At4g26180 GI:15236140
Arabidopsis thaliana (Ath) At4g32400 GI:15236783
Arabidopsis thaliana (Ath) At5g01500 GI:15240999
Arabidopsis thaliana (Ath) At5g48970 GI:15239754
Arabidopsis thaliana (Ath) At5g64970 GI:15238315
Caenorhabditis elegans (Cel) CE10358
(WBGene00009666)		 GI:17507311 Q93717
Caenorhabditis elegans (Cel) CE29222
(WBGene00016588)		 GI:17539126 A3QMB9
Drosophila melanogaster (Dme) 7291871 GI:20130387
Drosophila melanogaster (Dme) 7299384 GI:7299384
Drosophila melanogaster (Dme) 7300625 GI:7300625
Homo sapiens (Hsa) Hs11119432 GI:11119432
Homo sapiens (Hsa) Hs15011910 GI:15011910
Homo sapiens (Hsa) Hs20548100 GI:20548100
Homo sapiens (Hsa) Hs21687151 GI:18044568 Q9BR35
Homo sapiens (Hsa) Hs22053628 GI:20988432 P16260
Saccharomyces cerevisiae (Sce) YGR096w
(S000003328)		 GI:6321533 P53257
Saccharomyces cerevisiae (Sce) YHR002w
(S000001044)		 GI:6321789 P38702
Saccharomyces cerevisiae (Sce) YPR011c GI:6325268 Q12251
Schizosaccharomyces pombe (Spo) SPAC17H9.08 GI:19114490 O13805
Schizosaccharomyces pombe (Spo) SPBC1604.04 GI:19113428 O94370


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt4g01100
At4g32400
At5g64970
At5g01500
SceS000001044
YPR011c
SpoSPBC1604.04
GO:0005740 mitochondrial envelope C
IDA
SceS000003328
GO:0005743 mitochondrial inner membrane C
IDA
SceS000001044
ISS
AthAt2g37890
At4g01100
At5g48970
At5g64970
At4g26180
At3g55640
At3g20240
At1g78180
At3g53940
At3g51870
At3g21390
At1g14560
At4g32400
At5g01500
SceYPR011c
SpoSPBC1604.04
SPAC17H9.08
GO:0005886 plasma membrane C
IDA
AthAt3g55640
At4g01100
GO:0009507 chloroplast C
IDA
AthAt3g51870
At5g01500
At4g32400
GO:0009526 plastid envelope C
IDA
AthAt5g01500
GO:0009536 plastid C
IDA
AthAt5g64970
At4g01100
At4g32400
At5g01500
GO:0009941 chloroplast envelope C
IDA
AthAt3g51870
At5g01500
GO:0016020 membrane C
IDA
AthAt4g01100
GO:0042651 thylakoid membrane C
IDA
AthAt5g01500
GO:0005215 transporter activity F
ISS
AthAt4g26180
At3g55640
At5g64970
At2g37890
At3g51870
At1g14560
At3g20240
At3g53940
At3g21390
At4g32400
At5g01500
SceYPR011c
GO:0005347 ATP transmembrane transporter activity F
IDA
AthAt4g01100
At5g01500
GO:0005488 binding F
ISS
AthAt1g14560
At5g48970
At5g64970
At2g37890
At3g20240
At1g78180
At3g51870
At4g01100
At3g55640
At3g53940
At4g26180
At3g21390
At4g32400
At5g01500
GO:0015215 nucleotide transmembrane transporter
activity		 F
IGI
AthAt4g32400
GO:0015217 ADP transmembrane transporter activity F
IDA
AthAt4g01100
GO:0015228 coenzyme A transmembrane transporter
activity		 F
IMP
SceS000001044
ISS
SpoSPAC17H9.08
GO:0015234 thiamin transmembrane transporter
activity		 F
IDA
SceS000003328
ISS
SpoSPBC1604.04
GO:0022857 transmembrane transporter activity F
RCA
SceYPR011c
GO:0080122 AMP transmembrane transporter activity F
IDA
AthAt4g01100
GO:0006414 translational elongation P
RCA
SceS000003328
GO:0006810 transport P
ISS
AthAt4g01100
At3g55640
At3g53940
At5g48970
At5g64970
At2g37890
At3g51870
At1g78180
At3g20240
At3g21390
At4g26180
At1g14560
At4g32400
At5g01500
SceYPR011c
GO:0006839 mitochondrial transport P
ISS
AthAt3g53940
At1g14560
At3g55640
At5g48970
At5g64970
At3g20240
At2g37890
At1g78180
At4g01100
At4g26180
At3g21390
At4g32400
SpoSPAC17H9.08
NAS
SpoSPBC1604.04
GO:0006862 nucleotide transport P
IGI
AthAt4g32400
GO:0009060 aerobic respiration P
IDA
AthAt4g01100
GO:0009624 response to nematode P
IEP
AthAt3g51870
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016588
WBGene00009666
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt4g32400
GO:0010117 photoprotection P
IMP
AthAt5g01500
GO:0010206 photosystem II repair P
IMP
AthAt5g01500
GO:0015866 ADP transport P
IDA
AthAt4g01100
GO:0015867 ATP transport P
IDA
AthAt4g01100
GO:0015880 coenzyme A transport P
IMP
SceS000001044
ISS
SpoSPAC17H9.08
GO:0015888 thiamin transport P
ISS
SpoSPBC1604.04
GO:0030974 thiamin pyrophosphate transport P
IDA
SceS000003328
IMP
SceS000003328
GO:0035349 coenzyme A transmembrane transport P
ISS
SpoSPAC17H9.08
GO:0035461 vitamin transmembrane transport P
ISS
SpoSPBC1604.04
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009666
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00016588
GO:0080121 AMP transport P
IDA
AthAt4g01100

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5982

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SLC25A19 GI:186928858
Pan troglodytes (Ptr) SLC25A19 GI:114670424
Canis familiaris (Cfa) SLC25A19 GI:57099337
Mus musculus (Mmu) Slc25a19
(MGI:1914533)		 GI:21313024 Q80XJ6
Rattus norvegicus (Rno) Slc25a19
(RGD:1359554)		 GI:56090443
Gallus gallus (Gga) SLC25A19 GI:118099972
Drosophila melanogaster (Dme) CG6608
(FBgn0037852)		 GI:21356397
Anopheles gambiae (Aga) AgaP_AGAP005113 GI:118784876
Anopheles gambiae (Aga) AgaP_AGAP006806 GI:158286811
Caenorhabditis elegans (Cel) C42C1.10
(CE29222;
WBGene00016588)		 GI:17539126 A3QMB9
Schizosaccharomyces pombe (Spo) SPBC1604.04 GI:19113428 O94370
Saccharomyces cerevisiae (Sce) TPC1
(S000003328)		 GI:6321533 P53257
Kluyveromyces lactis (Kla) KLLA0D15015g GI:50307493
Eremothecium gossypii (Ego) AGOS_AAR036W GI:45184859
Magnaporthe grisea (Mgr) MGG_00489 GI:39974729
Neurospora crassa (Ncr) NCU07384.1 GI:32414381
Arabidopsis thaliana (Ath) AT5G48970 GI:15239754
Arabidopsis thaliana (Ath) AT3G21390 GI:18402984
Oryza sativa (Osa) Os01g0934200 GI:115442059


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1914533
SpoSPBC1604.04
GO:0005740 mitochondrial envelope C
IDA
SceS000003328
ISS
DmeFBgn0037852
GO:0005743 mitochondrial inner membrane C
ISS
AthAt5g48970
At3g21390
SpoSPBC1604.04
NAS
HsaSLC25A19
GO:0005215 transporter activity F
ISS
AthAt3g21390
GO:0005488 binding F
ISS
AthAt5g48970
At3g21390
GO:0015234 thiamin transmembrane transporter
activity		 F
IDA
SceS000003328
ISS
SpoSPBC1604.04
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0037852
GO:0030233 deoxynucleotide transmembrane transporter
activity		 F
TAS
HsaSLC25A19
GO:0006414 translational elongation P
RCA
SceS000003328
GO:0006810 transport P
ISS
AthAt5g48970
At3g21390
GO:0006839 mitochondrial transport P
ISS
AthAt5g48970
At3g21390
NAS
SpoSPBC1604.04
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016588
GO:0015888 thiamin transport P
ISS
SpoSPBC1604.04
GO:0030302 deoxynucleotide transport P
NAS
HsaSLC25A19
GO:0030974 thiamin pyrophosphate transport P
IDA
SceS000003328
IMP
SceS000003328
GO:0035461 vitamin transmembrane transport P
ISS
SpoSPBC1604.04
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00016588

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2685

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga490 ENSANGP00000009911
Anopheles gambiae (Aga) aga2260 ENSANGP00000013246
Ashbya gossypii (Ago) ago222 AAR036W
Arabidopsis thaliana (Ath) ath14438 At3g21390.1
Arabidopsis thaliana (Ath) ath26806 At5g48970.1
Caenorhabditis elegans (Cel) cel3874 C42C1.10
(CE29222;
WBGene00016588)
Candida glabrata (Cgl) cgl1760 CAGL0G03135g
Dictyostelium discoideum (Ddi) ddi6689 DDB0206413
Debaryomyces hansenii (Dha) dha3728 DEHA0E11022g
Drosophila melanogaster (Dme) dme7112 CG2857-PA
(FBgn0035078)
Drosophila melanogaster (Dme) dme11971 CG6608-PA
(FBgn0037852)
Drosophila melanogaster (Dme) dme11970 CG6608-PB
(FBgn0037852)
Danio rerio (Dre) dre22319 ENSDARP00000007831
Takifugu rubripes (Fru) fru20647 SINFRUP00000135321
Takifugu rubripes (Fru) fru20648 SINFRUP00000165860
Gallus gallus (Gga) gga16582 ENSGALP00000012987
(SLC25A19)
Gallus gallus (Gga) gga16583 ENSGALP00000012988
Homo sapiens (Hsa) hsa14329 ENSP00000319574
(SLC25A19)		 Q9HC21
Kluyveromyces lactis (Kla) kla2725 KLLA0D15015g
Mus musculus (Mmu) mmu5146 ENSMUSP00000021089
(MGI:1914533)		 Q9DAM5
Neurospora crassa (Ncr) ncr7188 NCU07384.2
Oryza sativa (Osa) osa13346 2864.m00134
Oryza sativa (Osa) osa35287 4773.m00190
Oryza sativa (Osa) osa35316 4773.m00243
Rattus norvegicus (Rno) rno6436 ENSRNOP00000005292
(RGD:1359554)		 Q6AYL0
Rattus norvegicus (Rno) rno2006 ENSRNOP00000021855
(RGD:1561206)
Saccharomyces cerevisiae (Sce) sce2464 YGR096W
(S000003328)
Schizosaccharomyces pombe (Spo) spo918 SPBC1604.04 O94370
Yarrowia lipolytica (Yli) yli6193 YALI0F20262g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1914533
SpoSPBC1604.04
GO:0005740 mitochondrial envelope C
IDA
SceS000003328
ISS
DmeFBgn0037852
FBgn0035078
GO:0005743 mitochondrial inner membrane C
ISS
AthAt5g48970
At3g21390
DmeFBgn0035078
SpoSPBC1604.04
GO:0005215 transporter activity F
ISS
AthAt3g21390
GO:0005488 binding F
ISS
AthAt5g48970
At3g21390
GO:0015234 thiamin transmembrane transporter
activity		 F
IDA
SceS000003328
ISS
SpoSPBC1604.04
GO:0017077 oxidative phosphorylation uncoupler
activity		 F
ISS
DmeFBgn0035078
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0037852
FBgn0035078
GO:0006414 translational elongation P
RCA
SceS000003328
GO:0006810 transport P
ISS
AthAt5g48970
At3g21390
GO:0006839 mitochondrial transport P
ISS
AthAt5g48970
At3g21390
NAS
SpoSPBC1604.04
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016588
GO:0015888 thiamin transport P
ISS
SpoSPBC1604.04
GO:0030974 thiamin pyrophosphate transport P
IDA
SceS000003328
IMP
SceS000003328
GO:0035461 vitamin transmembrane transport P
ISS
SpoSPBC1604.04
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00016588

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1604.04
(O94370)		 YGR096W
(S000003328)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SpoSPBC1604.04
GO:0005740 mitochondrial envelope C
IDA
SceS000003328
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPBC1604.04
GO:0015234 thiamin transmembrane transporter
activity		 F
IDA
SceS000003328
ISS
SpoSPBC1604.04
GO:0006414 translational elongation P
RCA
SceS000003328
GO:0006839 mitochondrial transport P
NAS
SpoSPBC1604.04
GO:0015888 thiamin transport P
ISS
SpoSPBC1604.04
GO:0030974 thiamin pyrophosphate transport P
IDA
SceS000003328
IMP
SceS000003328
GO:0035461 vitamin transmembrane transport P
ISS
SpoSPBC1604.04

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