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Search term: YGR116W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPT6
SGD link S000003348
Alternative ID YGR116W
Description Transcription elongation factor required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region
Synonyms YGR116W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1856 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Transcription elongation factor SPT6

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63210 GI:15221717
Arabidopsis thaliana (Ath) At1g65440 GI:15218682
Caenorhabditis elegans (Cel) CE13120
(WBGene00001259)		 GI:17552892 P34703
Drosophila melanogaster (Dme) 7290693 GI:7290693
Homo sapiens (Hsa) Hs11321573 GI:11321573
Saccharomyces cerevisiae (Sce) YGR116w
(S000003348)		 GI:6321552 P23615
Schizosaccharomyces pombe (Spo) SPAC1F7.01c GI:19115399 Q09915
Encephalitozoon cuniculi (Ecu) ECU07g1690 GI:19074590 Q8SRG7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
ISS
SpoSPAC1F7.01c
GO:0005575 cellular_component C
ND
AthAt1g65440
GO:0005634 nucleus C
IDA
SpoSPAC1F7.01c
IPI
SceS000003348
GO:0005739 mitochondrion C
IDA
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0008023 transcription elongation factor
complex		 C
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000003348
GO:0002119 nematode larval development P
IMP
CelWBGene00001259
GO:0006333 chromatin assembly or disassembly P
ISS
AthAt1g65440
GO:0006334 nucleosome assembly P
IDA
SceS000003348
GO:0006336 DNA replication-independent nucleosome
assembly		 P
ISS
SpoSPAC1F7.01c
GO:0006352 transcription initiation P
ISS
AthAt1g65440
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003348
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001259
GO:0032784 regulation of RNA elongation P
ISS
SpoSPAC1F7.01c
GO:0034401 regulation of transcription by chromatin
organization		 P
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0040007 growth P
IMP
CelWBGene00001259
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001259
GO:0043486 histone exchange P
NAS
SpoSPAC1F7.01c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003348

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40661

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SUPT6H GI:27597090
Pan troglodytes (Ptr) SUPT6H GI:114668449
Canis familiaris (Cfa) SUPT6H GI:73966996
Mus musculus (Mmu) Supt6h
(MGI:107726)		 GI:6678183 Q3TY72
Rattus norvegicus (Rno) Supt6h
(RGD:1309290)		 GI:62656585
Gallus gallus (Gga) SUPT6H GI:118100214
Drosophila melanogaster (Dme) Spt6
(FBgn0028982)		 GI:24640080
Anopheles gambiae (Aga) AgaP_AGAP003619 GI:158291858
Caenorhabditis elegans (Cel) emb-5
(CE13120;
WBGene00001259)		 GI:17552892 P34703
Schizosaccharomyces pombe (Spo) spt6
(SPAC1F7.01c)		 GI:63054631 Q09915
Saccharomyces cerevisiae (Sce) SPT6
(S000003348)		 GI:6321552 P23615
Kluyveromyces lactis (Kla) KLLA0B11385g GI:50304173
Eremothecium gossypii (Ego) AGOS_AAR031W GI:45184854
Magnaporthe grisea (Mgr) MGG_11491 GI:145610927
Neurospora crassa (Ncr) NCU04611.1 GI:32406708
Arabidopsis thaliana (Ath) GTB1 GI:42562972
Arabidopsis thaliana (Ath) AT1G63210 GI:15221717
Oryza sativa (Osa) Os05g0494900 GI:115464655


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IPI
DmeFBgn0028982
GO:0000790 nuclear chromatin C
ISS
SpoSPAC1F7.01c
GO:0005575 cellular_component C
ND
AthGTB1
GO:0005634 nucleus C
IDA
SpoSPAC1F7.01c
IPI
SceS000003348
NAS
HsaSUPT6H
GO:0005700 polytene chromosome C
IDA
DmeFBgn0028982
GO:0005703 polytene chromosome puff C
IDA
DmeFBgn0028982
GO:0005705 polytene chromosome interband C
IDA
DmeFBgn0028982
GO:0005739 mitochondrion C
IDA
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0008023 transcription elongation factor
complex		 C
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0003682 chromatin binding F
ISS
DmeFBgn0028982
GO:0003700 transcription factor activity F
TAS
HsaSUPT6H
GO:0003711 transcription elongation regulator
activity		 F
NAS
DmeFBgn0028982
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000003348
GO:0002119 nematode larval development P
IMP
CelWBGene00001259
GO:0006333 chromatin assembly or disassembly P
ISS
AthGTB1
GO:0006334 nucleosome assembly P
IDA
SceS000003348
GO:0006336 DNA replication-independent nucleosome
assembly		 P
ISS
SpoSPAC1F7.01c
GO:0006338 chromatin remodeling P
NAS
HsaSUPT6H
GO:0006352 transcription initiation P
ISS
AthGTB1
GO:0006354 RNA elongation P
NAS
DmeFBgn0028982
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003348
NAS
HsaSUPT6H
GO:0006366 transcription from RNA polymerase II
promoter		 P
IEP
DmeFBgn0028982
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001259
GO:0032784 regulation of RNA elongation P
ISS
SpoSPAC1F7.01c
GO:0034401 regulation of transcription by chromatin
organization		 P
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0040007 growth P
IMP
CelWBGene00001259
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001259
GO:0043486 histone exchange P
NAS
SpoSPAC1F7.01c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003348

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1620

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6076 ENSANGP00000011330
Anopheles gambiae (Aga) aga6077 ENSANGP00000028054
Ashbya gossypii (Ago) ago217 AAR031W
Arabidopsis thaliana (Ath) ath5521 At1g63210.1
Arabidopsis thaliana (Ath) ath5767 At1g65440.1
Caenorhabditis elegans (Cel) cel14446 T04A8.14
(CE13120;
WBGene00001259)
Candida glabrata (Cgl) cgl4287 CAGL0L04774g
Cryptococcus neoformans (Cne) cne4962 186.m03874
Dictyostelium discoideum (Ddi) ddi11792 DDB0231554
Debaryomyces hansenii (Dha) dha1602 DEHA0C03872g
Drosophila melanogaster (Dme) dme16696 CG12225-PA
(FBgn0028982)
Danio rerio (Dre) dre13764 ENSDARP00000013353
(supt6h)		 Q8UVK2
Encephalitozoon cuniculi (Ecu) ecu1976 19074590
Takifugu rubripes (Fru) fru28868 SINFRUP00000130246
Takifugu rubripes (Fru) fru28869 SINFRUP00000177337
Gallus gallus (Gga) gga24457 ENSGALP00000000199
(SUPT6H)
Gallus gallus (Gga) gga24458 ENSGALP00000000200
Homo sapiens (Hsa) hsa13343 ENSP00000319104
(SUPT6H)		 Q7KZ85-1
Homo sapiens (Hsa) hsa13344 ENSP00000338143
(SUPT6H)		 Q7KZ85-3
Homo sapiens (Hsa) hsa13342 ENSP00000352210
(PDLIM5)		 Q56VN4
Kluyveromyces lactis (Kla) kla1034 KLLA0B11385g
Mus musculus (Mmu) mmu4321 ENSMUSP00000002121
(MGI:107726)		 Q62383
Neurospora crassa (Ncr) ncr4479 NCU04611.2
Oryza sativa (Osa) osa24928 3834.m00134
Plasmodium falciparum (Pfa) pfa1315 PF14_0059
Rattus norvegicus (Rno) rno5614 ENSRNOP00000016759
(RGD:1309290)		 B5DFK4
Saccharomyces cerevisiae (Sce) sce2486 YGR116W
(S000003348)
Schizosaccharomyces pombe (Spo) spo3434 SPAC1F7.01c Q09915
Yarrowia lipolytica (Yli) yli796 YALI0B01232g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IPI
DmeFBgn0028982
GO:0000790 nuclear chromatin C
ISS
SpoSPAC1F7.01c
GO:0005575 cellular_component C
ND
AthAt1g65440
GO:0005634 nucleus C
IDA
SpoSPAC1F7.01c
IPI
SceS000003348
GO:0005700 polytene chromosome C
IDA
DmeFBgn0028982
GO:0005703 polytene chromosome puff C
IDA
DmeFBgn0028982
GO:0005705 polytene chromosome interband C
IDA
DmeFBgn0028982
GO:0005739 mitochondrion C
IDA
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0008023 transcription elongation factor
complex		 C
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0003682 chromatin binding F
ISS
DmeFBgn0028982
GO:0003711 transcription elongation regulator
activity		 F
NAS
DmeFBgn0028982
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000003348
GO:0002119 nematode larval development P
IMP
CelWBGene00001259
GO:0006333 chromatin assembly or disassembly P
ISS
AthAt1g65440
GO:0006334 nucleosome assembly P
IDA
SceS000003348
GO:0006336 DNA replication-independent nucleosome
assembly		 P
ISS
SpoSPAC1F7.01c
GO:0006352 transcription initiation P
ISS
AthAt1g65440
GO:0006354 RNA elongation P
NAS
DmeFBgn0028982
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003348
GO:0006366 transcription from RNA polymerase II
promoter		 P
IEP
DmeFBgn0028982
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001259
GO:0032784 regulation of RNA elongation P
ISS
SpoSPAC1F7.01c
GO:0034401 regulation of transcription by chromatin
organization		 P
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0040007 growth P
IMP
CelWBGene00001259
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001259
GO:0043486 histone exchange P
NAS
SpoSPAC1F7.01c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003348

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1F7.01c
(Q09915)		 YGR116W
(S000003348)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
ISS
SpoSPAC1F7.01c
GO:0005634 nucleus C
IDA
SpoSPAC1F7.01c
IPI
SceS000003348
GO:0005739 mitochondrion C
IDA
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0008023 transcription elongation factor
complex		 C
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000003348
GO:0006334 nucleosome assembly P
IDA
SceS000003348
GO:0006336 DNA replication-independent nucleosome
assembly		 P
ISS
SpoSPAC1F7.01c
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000003348
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IPI
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0032784 regulation of RNA elongation P
ISS
SpoSPAC1F7.01c
GO:0034401 regulation of transcription by chromatin
organization		 P
IMP
SceS000003348
ISS
SpoSPAC1F7.01c
GO:0043486 histone exchange P
NAS
SpoSPAC1F7.01c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003348

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GO info in one table:

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