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Search term: YGR158C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MTR3
SGD link S000003390
Alternative ID YGR158C
Description Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hMtr3p (EXOSC6)
Synonyms YGR158C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1068 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g61620 GI:15233167
Caenorhabditis elegans (Cel) CE20469
(WBGene00007201)		 GI:17538326
Caenorhabditis elegans (Cel) CE26236_1 GI:17555548
Drosophila melanogaster (Dme) 7293727 GI:7293727
Drosophila melanogaster (Dme) 7298022 GI:7298022
Homo sapiens (Hsa) Hs9506689
(EXOSC4)		 GI:9506689 Q9NPD3
Homo sapiens (Hsa) Hs20542749 GI:20542749
Homo sapiens (Hsa) Hs17402904
(EXOSC6)		 GI:17402904 Q5RKV6
Saccharomyces cerevisiae (Sce) YGR158c
(S000003390)		 GI:6321597 P48240
Saccharomyces cerevisiae (Sce) YGR195w
(S000003427)		 GI:6321634 P46948
Schizosaccharomyces pombe (Spo) SPAC3G9.10c GI:19114994 O42872
Schizosaccharomyces pombe (Spo) SPBC211.08c GI:19113410 Q9P7R3
Encephalitozoon cuniculi (Ecu) ECU09g0830 GI:19173205
Arabidopsis thaliana (Ath) At3g61620 GI:15233167
Caenorhabditis elegans (Cel) CE20469
(WBGene00007201)		 GI:17538326
Caenorhabditis elegans (Cel) CE26236_1 GI:17555548
Drosophila melanogaster (Dme) 7293727 GI:7293727
Drosophila melanogaster (Dme) 7298022 GI:7298022
Homo sapiens (Hsa) Hs9506689
(EXOSC4)		 GI:9506689 Q9NPD3
Homo sapiens (Hsa) Hs20542749 GI:20542749
Homo sapiens (Hsa) Hs17402904
(EXOSC6)		 GI:17402904 Q5RKV6
Saccharomyces cerevisiae (Sce) YGR158c
(S000003390)		 GI:6321597 P48240
Saccharomyces cerevisiae (Sce) YGR195w
(S000003427)		 GI:6321634 P46948
Schizosaccharomyces pombe (Spo) SPAC3G9.10c GI:19114994 O42872
Schizosaccharomyces pombe (Spo) SPBC211.08c GI:19113410 Q9P7R3
Encephalitozoon cuniculi (Ecu) ECU09g0830 GI:19173205


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000003427
S000003390
ISS
SpoSPAC3G9.10c
SPBC211.08c
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000003427
S000003390
ISS
SpoSPAC3G9.10c
SPBC211.08c
GO:0005575 cellular_component C
ND
AthAt3g61620
GO:0005634 nucleus C
IDA
SpoSPAC3G9.10c
SPBC211.08c
GO:0005730 nucleolus C
IDA
SceS000003390
NAS
HsaEXOSC4
GO:0005737 cytoplasm C
NAS
HsaEXOSC4
GO:0005816 spindle pole body C
IDA
SpoSPAC3G9.10c
GO:0005829 cytosol C
IDA
SpoSPAC3G9.10c
SPBC211.08c
GO:0000175 3'-5'-exoribonuclease activity F
ISS
AthAt3g61620
SpoSPAC3G9.10c
NAS
HsaEXOSC4
SpoSPBC211.08c
GO:0003674 molecular_function F
ND
SceS000003390
S000003427
GO:0003723 RNA binding F
ISS
AthAt3g61620
GO:0005515 protein binding F
IPI
HsaEXOSC4
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000003390
S000003427
GO:0002119 nematode larval development P
IMP
CelWBGene00007201
GO:0006364 rRNA processing P
ISS
SpoSPAC3G9.10c
SPBC211.08c
NAS
HsaEXOSC4
GO:0006396 RNA processing P
ISS
AthAt3g61620
GO:0006402 mRNA catabolic process P
ISS
SpoSPAC3G9.10c
SPBC211.08c
GO:0008406 gonad development P
IMP
CelWBGene00007201
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007201
GO:0010171 body morphogenesis P
IMP
CelWBGene00007201
GO:0016075 rRNA catabolic process P
IMP
SceS000003427
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000003390
IMP
SceS000003427
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000003427
IMP
SceS000003427
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000003427
IMP
SceS000003427
S000003390
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000003427
IMP
SceS000003427
GO:0040007 growth P
IMP
CelWBGene00007201
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007201
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007201
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000003390
IGI
SceS000003427
IMP
SceS000003427
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000003390
S000003427
GO:0070651 nonfunctional rRNA decay P
IC
SceS000003427
S000003390
GO:0071028 nuclear mRNA surveillance P
IGI
SceS000003427
IMP
SceS000003427
S000003390
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000003390
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000003390
S000003427
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IMP
SceS000003390
S000003427
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000003390
S000003427
GO:0071044 histone mRNA catabolic process P
IMP
HsaEXOSC4
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000003390
S000003427

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39139

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MTR3
(S000003390)		 GI:6321597 P48240
Kluyveromyces lactis (Kla) KLLA0F18304g GI:50311745
Eremothecium gossypii (Ego) AGOS_AFR109W GI:45198627


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000003390
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000003390
GO:0005730 nucleolus C
IDA
SceS000003390
GO:0003674 molecular_function F
ND
SceS000003390
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000003390
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000003390
GO:0034475 U4 snRNA 3'-end processing P
IMP
SceS000003390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000003390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000003390
GO:0070651 nonfunctional rRNA decay P
IC
SceS000003390
GO:0071028 nuclear mRNA surveillance P
IMP
SceS000003390
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000003390
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000003390
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IMP
SceS000003390
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000003390
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000003390

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_17617

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3301 AFR109W
Candida glabrata (Cgl) cgl1082 CAGL0E03223g
Debaryomyces hansenii (Dha) dha596 DEHA0A13343g
Kluyveromyces lactis (Kla) kla4901 KLLA0F18304g
Neurospora crassa (Ncr) ncr7818 NCU08026.2
Saccharomyces cerevisiae (Sce) sce2531 YGR158C
(S000003390)
Yarrowia lipolytica (Yli) yli4116 YALI0E06039g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000003390
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000003390
GO:0005730 nucleolus C
IDA
SceS000003390
GO:0003674 molecular_function F
ND
SceS000003390
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000003390
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000003390
GO:0034475 U4 snRNA 3'-end processing P
IMP
SceS000003390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000003390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000003390
GO:0070651 nonfunctional rRNA decay P
IC
SceS000003390
GO:0071028 nuclear mRNA surveillance P
IMP
SceS000003390
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000003390
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000003390
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IMP
SceS000003390
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000003390
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000003390

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC211.08c
(Q9P7R3)		 YGR158C
(S000003390)