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Search term: YGR180C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RNR4
SGD link S000003412
Alternative ID YGR180C
Description Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
Synonyms YGR180C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1567 ACDHYPE

KOGs classification KOGs description
METABOLISM Ribonucleotide reductase, beta subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g23580 GI:15229476
Arabidopsis thaliana (Ath) At3g27060 GI:15232077
Caenorhabditis elegans (Cel) CE00874
(WBGene00004392)
GI:17551968 P42170
Caenorhabditis elegans (Cel) CE07085_2 GI:17567153 Q19599
Drosophila melanogaster (Dme) 7303545 GI:7303545
Homo sapiens (Hsa) Hs4557845
(RRM2)
GI:4557845 P31350
Homo sapiens (Hsa) Hs14743689 GI:14743689
Homo sapiens (Hsa) Hs17435183 GI:17435183
Saccharomyces cerevisiae (Sce) YGR180c
(S000003412)
GI:6321619 P49723
Saccharomyces cerevisiae (Sce) YJL026w
(S000003563)
GI:6322434 P09938
Schizosaccharomyces pombe (Spo) SPBC25D12.04 GI:19113338 P36603
Encephalitozoon cuniculi (Ecu) ECU06g0730 GI:19074323 Q8SRR2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g27060
GO:0005634 nucleus C
IDA
SceS000003563
S000003412
SpoSPBC25D12.04
GO:0005737 cytoplasm C
IDA
SceS000003563
S000003412
SpoSPBC25D12.04
NAS
HsaRRM2
GO:0005829 cytosol C
IDA
SpoSPBC25D12.04
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003412
S000003563
IPI
SceS000003412
ISS
AthAt3g23580
TAS
SpoSPBC25D12.04
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IDA
AthAt3g23580
SceS000003412
S000003563
S000003563
IGI
SceS000003412
IMP
SceS000003412
S000003412
ISS
AthAt3g27060
At3g23580
HsaRRM2
NAS
HsaRRM2
TAS
SpoSPBC25D12.04
GO:0005515 protein binding F
IPI
SpoSPBC25D12.04
GO:0000003 reproduction P
IMP
CelWBGene00004392
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00004392
GO:0006066 alcohol metabolic process P
RCA
SceS000003563
GO:0006213 pyrimidine nucleoside metabolic
process
P
IC
SpoSPBC25D12.04
GO:0006260 DNA replication P
IMP
AthAt3g27060
NAS
HsaRRM2
GO:0006281 DNA repair P
TAS
AthAt3g27060
At3g23580
GO:0006414 translational elongation P
RCA
SceS000003412
S000003563
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00004392
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00017610
GO:0007090 regulation of S phase of mitotic cell
cycle
P
IC
SpoSPBC25D12.04
GO:0007275 multicellular organismal development P
IMP
AthAt3g27060
At3g23580
GO:0007276 gamete generation P
IMP
CelWBGene00004392
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004392
GO:0009186 deoxyribonucleoside diphosphate metabolic
process
P
ISS
AthAt3g27060
At3g23580
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthetic process
P
IC
SpoSPBC25D12.04
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthetic process
P
IC
SpoSPBC25D12.04
GO:0009259 ribonucleotide metabolic process P
TAS
AthAt3g23580
GO:0009263 deoxyribonucleotide biosynthetic
process
P
IDA
SceS000003412
S000003563
ISS
HsaRRM2
GO:0009790 embryo development P
IMP
CelWBGene00004392
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004392
GO:0012501 programmed cell death P
IMP
AthAt3g27060
GO:0019915 lipid storage P
IMP
CelWBGene00017610
GO:0030728 ovulation P
IMP
CelWBGene00004392
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004392
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004392
GO:0042278 purine nucleoside metabolic process P
IC
SpoSPBC25D12.04
GO:0051188 cofactor biosynthetic process P
IMP
SceS000003412
IPI
SceS000003412
GO:0051726 regulation of cell cycle P
IMP
AthAt3g27060
At3g23580
GO:0090329 regulation of DNA-dependent DNA
replication
P
TAS
SpoSPBC25D12.04

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_60035

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Candida glabrata (Cgl) cgl1807 CAGL0G04213g
Saccharomyces cerevisiae (Sce) sce2560 YGR180C
(S000003412)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003412
GO:0005737 cytoplasm C
IDA
SceS000003412
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003412
IPI
SceS000003412
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IDA
SceS000003412
IGI
SceS000003412
IMP
SceS000003412
S000003412
GO:0006414 translational elongation P
RCA
SceS000003412
GO:0009263 deoxyribonucleotide biosynthetic
process
P
IDA
SceS000003412
GO:0051188 cofactor biosynthetic process P
IMP
SceS000003412
IPI
SceS000003412

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC25D12.04
(P36603)
YGR180C
(S000003412)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003412
SpoSPBC25D12.04
GO:0005737 cytoplasm C
IDA
SceS000003412
SpoSPBC25D12.04
GO:0005829 cytosol C
IDA
SpoSPBC25D12.04
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003412
IPI
SceS000003412
TAS
SpoSPBC25D12.04
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IDA
SceS000003412
IGI
SceS000003412
IMP
SceS000003412
S000003412
TAS
SpoSPBC25D12.04
GO:0005515 protein binding F
IPI
SpoSPBC25D12.04
GO:0006213 pyrimidine nucleoside metabolic
process
P
IC
SpoSPBC25D12.04
GO:0006414 translational elongation P
RCA
SceS000003412
GO:0007090 regulation of S phase of mitotic cell
cycle
P
IC
SpoSPBC25D12.04
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthetic process
P
IC
SpoSPBC25D12.04
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthetic process
P
IC
SpoSPBC25D12.04
GO:0009263 deoxyribonucleotide biosynthetic
process
P
IDA
SceS000003412
GO:0042278 purine nucleoside metabolic process P
IC
SpoSPBC25D12.04
GO:0051188 cofactor biosynthetic process P
IMP
SceS000003412
IPI
SceS000003412
GO:0090329 regulation of DNA-dependent DNA
replication
P
TAS
SpoSPBC25D12.04

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GO info in one table:

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