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Search term: YGR193C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDX1
SGD link S000003425
Alternative ID YGR193C
Description Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core
Synonyms YGR193C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0557 ACDHYP-

KOGs classification KOGs description
METABOLISM Dihydrolipoamide acetyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g34430 GI:15218630
Arabidopsis thaliana (Ath) At1g54220 GI:15221756
Arabidopsis thaliana (Ath) At3g13930 GI:15231415
Arabidopsis thaliana (Ath) At3g25860 GI:15230922
Arabidopsis thaliana (Ath) At3g52200 GI:15231159
Caenorhabditis elegans (Cel) CE09597
(WBGene00009082)		 GI:17560088 Q19749
Caenorhabditis elegans (Cel) CE15651
(WBGene00007824)		 GI:17538894 O45279
Drosophila melanogaster (Dme) 7297250
(FBgn0031912)		 GI:20129315 Q7KTK9
Homo sapiens (Hsa) Hs17458911 GI:17458911
Homo sapiens (Hsa) Hs21630255 GI:320108
Homo sapiens (Hsa) Hs4505699 GI:4505699
Saccharomyces cerevisiae (Sce) YGR193c
(S000003425)		 GI:6321632 P16451
Saccharomyces cerevisiae (Sce) YNL071w
(S000005015)		 GI:6324258 P12695
Schizosaccharomyces pombe (Spo) SPCC1259.09c GI:19075565 O94709
Schizosaccharomyces pombe (Spo) SPCC794.07 GI:19075255 O59816
Arabidopsis thaliana (Ath) At1g34430 GI:15218630
Arabidopsis thaliana (Ath) At1g54220 GI:15221756
Arabidopsis thaliana (Ath) At3g13930 GI:15231415
Arabidopsis thaliana (Ath) At3g25860 GI:15230922
Arabidopsis thaliana (Ath) At3g52200 GI:15231159
Caenorhabditis elegans (Cel) CE09597
(WBGene00009082)		 GI:17560088 Q19749
Caenorhabditis elegans (Cel) CE15651
(WBGene00007824)		 GI:17538894 O45279
Drosophila melanogaster (Dme) 7297250
(FBgn0031912)		 GI:20129315 Q7KTK9
Homo sapiens (Hsa) Hs17458911 GI:17458911
Homo sapiens (Hsa) Hs21630255 GI:320108
Homo sapiens (Hsa) Hs4505699 GI:4505699
Saccharomyces cerevisiae (Sce) YGR193c
(S000003425)		 GI:6321632 P16451
Saccharomyces cerevisiae (Sce) YNL071w
(S000005015)		 GI:6324258 P12695
Schizosaccharomyces pombe (Spo) SPCC1259.09c GI:19075565 O94709
Schizosaccharomyces pombe (Spo) SPCC794.07 GI:19075255 O59816


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt3g52200
At1g54220
At3g13930
SceS000005015
S000003425
SpoSPCC1259.09c
SPCC794.07
GO:0005811 lipid particle C
IDA
DmeFBgn0031912
GO:0005886 plasma membrane C
IDA
AthAt1g34430
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000003425
S000005015
IPI
SceS000003425
S000005015
ISS
DmeFBgn0031912
SpoSPCC1259.09c
SPCC794.07
GO:0009507 chloroplast C
IDA
AthAt1g34430
At3g13930
At3g25860
GO:0009570 chloroplast stroma C
IDA
AthAt3g25860
GO:0009941 chloroplast envelope C
IDA
AthAt3g13930
At3g25860
At1g34430
GO:0016020 membrane C
IDA
AthAt3g25860
GO:0022626 cytosolic ribosome C
IDA
AthAt1g34430
At3g25860
GO:0004742 dihydrolipoyllysine-residue acetyltransferase
activity		 F
IDA
AthAt3g25860
SceS000005015
ISS
AthAt3g52200
At3g13930
At1g54220
At1g34430
At3g25860
DmeFBgn0031912
SpoSPCC794.07
GO:0005198 structural molecule activity F
IDA
SceS000003425
IMP
SceS000003425
GO:0005507 copper ion binding F
IDA
AthAt3g13930
GO:0005524 ATP binding F
IDA
AthAt3g52200
GO:0000003 reproduction P
IMP
CelWBGene00009082
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000003425
S000005015
IMP
SceS000003425
ISS
DmeFBgn0031912
SpoSPCC1259.09c
SPCC794.07
TAS
AthAt3g25860
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00009082
GO:0008152 metabolic process P
ISS
AthAt3g25860
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009082
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g34430
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009082
GO:0055114 oxidation reduction P
RCA
SceS000005015

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
28787

Species Gene ID NCBI link UniProt link
Gallus gallus (Gga) LOC769870 GI:118091472
Saccharomyces cerevisiae (Sce) PDX1
(S000003425)		 GI:6321632 P16451
Kluyveromyces lactis (Kla) KLLA0E09768g GI:50308773
Eremothecium gossypii (Ego) AGOS_AGR323C GI:45201419
Magnaporthe grisea (Mgr) MGG_08842 GI:39953580
Neurospora crassa (Ncr) NCU00050.1 GI:32403046


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003425
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000003425
IPI
SceS000003425
GO:0005198 structural molecule activity F
IDA
SceS000003425
IMP
SceS000003425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000003425
IMP
SceS000003425

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_10377

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4634 AGR323C
Candida glabrata (Cgl) cgl2030 CAGL0G09361g
Cryptococcus neoformans (Cne) cne4175 177.m02934
Cryptococcus neoformans (Cne) cne4176 177.m03315
Debaryomyces hansenii (Dha) dha2604 DEHA0D06952g
Kluyveromyces lactis (Kla) kla3390 KLLA0E09768g
Neurospora crassa (Ncr) ncr49 NCU00050.2
Saccharomyces cerevisiae (Sce) sce2573 YGR193C
(S000003425)
Schizosaccharomyces pombe (Spo) spo4384 SPCC1259.09c O94709
Yarrowia lipolytica (Yli) yli1141 YALI0B09845g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003425
SpoSPCC1259.09c
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000003425
IPI
SceS000003425
ISS
SpoSPCC1259.09c
GO:0005198 structural molecule activity F
IDA
SceS000003425
IMP
SceS000003425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000003425
IMP
SceS000003425
ISS
SpoSPCC1259.09c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1259.09c
(O94709)		 YGR193C
(S000003425)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003425
SpoSPCC1259.09c
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000003425
IPI
SceS000003425
ISS
SpoSPCC1259.09c
GO:0005198 structural molecule activity F
IDA
SceS000003425
IMP
SceS000003425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000003425
IMP
SceS000003425
ISS
SpoSPCC1259.09c

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