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Search term: YGR200C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ELP2
SGD link S000003432
Alternative ID YGR200C
Description Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
Synonyms YGR200C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1063 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g49540 GI:15222770
Caenorhabditis elegans (Cel) CE24138 GI:17556697
Drosophila melanogaster (Dme) 7303715 GI:7303715
Homo sapiens (Hsa) Hs8922735
(ELP2)		 GI:8922735 Q6IA86
Saccharomyces cerevisiae (Sce) YGR200c
(S000003432)		 GI:6321639 P42935
Schizosaccharomyces pombe (Spo) SPCC895.06 GI:19075547 O94533
Encephalitozoon cuniculi (Ecu) ECU01g0610 GI:19075071
Arabidopsis thaliana (Ath) At1g49540 GI:15222770
Caenorhabditis elegans (Cel) CE24138 GI:17556697
Drosophila melanogaster (Dme) 7303715 GI:7303715
Homo sapiens (Hsa) Hs8922735
(ELP2)		 GI:8922735 Q6IA86
Saccharomyces cerevisiae (Sce) YGR200c
(S000003432)		 GI:6321639 P42935
Schizosaccharomyces pombe (Spo) SPCC895.06 GI:19075547 O94533
Encephalitozoon cuniculi (Ecu) ECU01g0610 GI:19075071


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g49540
GO:0005634 nucleus C
IDA
SceS000003432
SpoSPCC895.06
GO:0005730 nucleolus C
IC
HsaELP2
GO:0005737 cytoplasm C
IC
HsaELP2
IDA
SceS000003432
GO:0005829 cytosol C
IDA
SpoSPCC895.06
GO:0008023 transcription elongation factor
complex		 C
IDA
HsaELP2
GO:0016591 DNA-directed RNA polymerase II,
holoenzyme		 C
IC
HsaELP2
GO:0033588 Elongator holoenzyme complex C
IDA
SceS000003432
ISS
SpoSPCC895.06
GO:0000166 nucleotide binding F
ISS
AthAt1g49540
GO:0003674 molecular_function F
ND
SceS000003432
SpoSPCC895.06
GO:0003677 DNA binding F
IDA
HsaELP2
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IC
HsaELP2
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000003432
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SceS000003432
TAS
HsaELP2
GO:0006399 tRNA metabolic process P
RCA
SceS000003432
GO:0006400 tRNA modification P
ISS
SpoSPCC895.06
GO:0008150 biological_process P
ND
AthAt1g49540
GO:0009451 RNA modification P
RCA
SceS000003432
GO:0032447 protein urmylation P
IMP
SceS000003432

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6019

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ELP2 GI:8922735 Q6IA86
Pan troglodytes (Ptr) ELP2 GI:114672863
Canis familiaris (Cfa) ELP2 GI:73961733
Mus musculus (Mmu) Elp2
(MGI:1889642)		 GI:134032030 Q91WG4
Rattus norvegicus (Rno) Elp2 GI:77628045
Gallus gallus (Gga) ELP2 GI:118086686
Drosophila melanogaster (Dme) StIP GI:19921984
Anopheles gambiae (Aga) AgaP_AGAP006889 GI:158286689
Schizosaccharomyces pombe (Spo) SPCC895.06 GI:19075547 O94533
Saccharomyces cerevisiae (Sce) ELP2
(S000003432)		 GI:6321639 P42935
Kluyveromyces lactis (Kla) KLLA0F22000g GI:50312061
Eremothecium gossypii (Ego) AGOS_ACL116W GI:45185572
Magnaporthe grisea (Mgr) MGG_03979 GI:145607107
Neurospora crassa (Ncr) NCU04176.1 GI:32405806
Arabidopsis thaliana (Ath) AT1G49540 GI:145336554
Oryza sativa (Osa) Os08g0493900 GI:115477058


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g49540
GO:0005634 nucleus C
IDA
SceS000003432
SpoSPCC895.06
GO:0005730 nucleolus C
IC
HsaELP2
GO:0005737 cytoplasm C
IC
HsaELP2
IDA
SceS000003432
GO:0005829 cytosol C
IDA
SpoSPCC895.06
GO:0008023 transcription elongation factor
complex		 C
IDA
HsaELP2
ISO
MmuMGI:1889642
GO:0016591 DNA-directed RNA polymerase II,
holoenzyme		 C
IC
HsaELP2
GO:0033588 Elongator holoenzyme complex C
IDA
SceS000003432
ISS
SpoSPCC895.06
GO:0000166 nucleotide binding F
ISS
AthAt1g49540
GO:0003674 molecular_function F
ND
SceS000003432
SpoSPCC895.06
GO:0003677 DNA binding F
IDA
HsaELP2
GO:0005515 protein binding F
IPI
MmuMGI:1889642
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
IC
HsaELP2
GO:0019901 protein kinase binding F
IDA
MmuMGI:1889642
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000003432
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SceS000003432
TAS
HsaELP2
GO:0006399 tRNA metabolic process P
RCA
SceS000003432
GO:0006400 tRNA modification P
ISS
SpoSPCC895.06
GO:0008150 biological_process P
ND
AthAt1g49540
GO:0009451 RNA modification P
RCA
SceS000003432
GO:0032447 protein urmylation P
IMP
SceS000003432
GO:0046425 regulation of JAK-STAT cascade P
IDA
MmuMGI:1889642

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1736

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2343 ENSANGP00000021636
Ashbya gossypii (Ago) ago933 ACL116W
Arabidopsis thaliana (Ath) ath4225 At1g49540.1
Caenorhabditis elegans (Cel) cel17648 Y111B2A.17
(CE34502;
WBGene00013738)
Candida glabrata (Cgl) cgl3561 CAGL0K00957g
Cryptococcus neoformans (Cne) cne4954 186.m03864
Dictyostelium discoideum (Ddi) ddi11836 DDB0231759
Debaryomyces hansenii (Dha) dha827 DEHA0B03256g
Drosophila melanogaster (Dme) dme4363 CG11887-PA
(FBgn0033540)
Danio rerio (Dre) dre10491 ENSDARP00000005147
Danio rerio (Dre) dre10495 ENSDARP00000039748
(zgc:153559)		 Q05AM5
Danio rerio (Dre) dre10494 ENSDARP00000042737
Danio rerio (Dre) dre10492 ENSDARP00000044057
Danio rerio (Dre) dre10493 ENSDARP00000050149
Encephalitozoon cuniculi (Ecu) ecu1708 19075071
Takifugu rubripes (Fru) fru26774 SINFRUP00000128924
Gallus gallus (Gga) gga10779 ENSGALP00000021532
Gallus gallus (Gga) gga10780 ENSGALP00000021533
Gallus gallus (Gga) gga10781 ENSGALP00000021534
Gallus gallus (Gga) gga10778 ENSGALP00000021535
(ELP2)
Homo sapiens (Hsa) hsa14905 ENSP00000257191
(ELP2)		 Q6IA86-3
Homo sapiens (Hsa) hsa14903 ENSP00000300265
Homo sapiens (Hsa) hsa14904 ENSP00000316051
(ELP2)		 B4DTG0
Homo sapiens (Hsa) hsa14906 ENSP00000350967
(ELP2)		 Q6IA86-1
Kluyveromyces lactis (Kla) kla5062 KLLA0F22000g
Mus musculus (Mmu) mmu12416 ENSMUSP00000025120
(MGI:1889642)		 Q91WG4-1
Neurospora crassa (Ncr) ncr4052 NCU04176.2
Oryza sativa (Osa) osa24230 3793.m00274
Oryza sativa (Osa) osa34373 4689.m00148
Rattus norvegicus (Rno) rno13865 ENSRNOP00000020601
(RGD:1306419)		 Q496Z0
Rattus norvegicus (Rno) rno13866 ENSRNOP00000020668
Rattus norvegicus (Rno) rno13867 ENSRNOP00000033049
Rattus norvegicus (Rno) rno13868 ENSRNOP00000033258
Saccharomyces cerevisiae (Sce) sce2580 YGR200C
(S000003432)
Schizosaccharomyces pombe (Spo) spo424 SPCC895.06 O94533
Yarrowia lipolytica (Yli) yli2659 YALI0C23386g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
ISS
DmeFBgn0033540
GO:0005575 cellular_component C
ND
AthAt1g49540
GO:0005634 nucleus C
IDA
SceS000003432
SpoSPCC895.06
GO:0005737 cytoplasm C
IDA
SceS000003432
GO:0005829 cytosol C
IDA
SpoSPCC895.06
GO:0008023 transcription elongation factor
complex		 C
ISO
MmuMGI:1889642
GO:0033588 Elongator holoenzyme complex C
IDA
SceS000003432
ISS
SpoSPCC895.06
GO:0000166 nucleotide binding F
ISS
AthAt1g49540
GO:0003674 molecular_function F
ND
SceS000003432
SpoSPCC895.06
GO:0005515 protein binding F
IPI
MmuMGI:1889642
GO:0019901 protein kinase binding F
IDA
MmuMGI:1889642
GO:0061133 endopeptidase activator activity F
ISS
DmeFBgn0033540
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000003432
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SceS000003432
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
ISS
DmeFBgn0033540
GO:0006399 tRNA metabolic process P
RCA
SceS000003432
GO:0006400 tRNA modification P
ISS
SpoSPCC895.06
GO:0008150 biological_process P
ND
AthAt1g49540
GO:0009451 RNA modification P
RCA
SceS000003432
GO:0032447 protein urmylation P
IMP
SceS000003432
GO:0043248 proteasome assembly P
ISS
DmeFBgn0033540
GO:0046425 regulation of JAK-STAT cascade P
IDA
MmuMGI:1889642

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC895.06
(O94533)		 YGR200C
(S000003432)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003432
SpoSPCC895.06
GO:0005737 cytoplasm C
IDA
SceS000003432
GO:0005829 cytosol C
IDA
SpoSPCC895.06
GO:0033588 Elongator holoenzyme complex C
IDA
SceS000003432
ISS
SpoSPCC895.06
GO:0003674 molecular_function F
ND
SceS000003432
SpoSPCC895.06
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000003432
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SceS000003432
GO:0006399 tRNA metabolic process P
RCA
SceS000003432
GO:0006400 tRNA modification P
ISS
SpoSPCC895.06
GO:0009451 RNA modification P
RCA
SceS000003432
GO:0032447 protein urmylation P
IMP
SceS000003432

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Query species:

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GO info in one table:

s.khadayate@ucl.ac.uk