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Search term: YGR231C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PHB2
SGD link S000003463
Alternative ID YGR231C
Description Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
Synonyms YGR231C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3090 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Prohibitin-like protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03860 GI:15219569
Arabidopsis thaliana (Ath) At2g20530 GI:15225374
Arabidopsis thaliana (Ath) At4g28510 GI:15235317
Arabidopsis thaliana (Ath) At5g44140 GI:15241424
Caenorhabditis elegans (Cel) CE02883 GI:17536479
Drosophila melanogaster (Dme) 7302549 GI:18485188
Homo sapiens (Hsa) Hs6005854 GI:6005854 Q9BXV3
Saccharomyces cerevisiae (Sce) YGR231c
(S000003463)
GI:6321670
Schizosaccharomyces pombe (Spo) SPCC1322.16 GI:19075644 O94550


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt1g03860
GO:0005739 mitochondrion C
IDA
AthAt2g20530
At1g03860
At4g28510
At5g44140
SceS000003463
GO:0005743 mitochondrial inner membrane C
IDA
SceS000003463
ISS
SpoSPCC1322.16
GO:0005747 mitochondrial respiratory chain complex
I
C
IDA
AthAt2g20530
At1g03860
GO:0005773 vacuole C
IDA
AthAt1g03860
GO:0005886 plasma membrane C
IDA
AthAt1g03860
At2g20530
At4g28510
GO:0009507 chloroplast C
IDA
AthAt1g03860
GO:0009536 plastid C
IDA
AthAt1g03860
GO:0016020 membrane C
IDA
AthAt5g44140
At2g20530
GO:0045271 respiratory chain complex I C
IDA
AthAt2g20530
At1g03860
At4g28510
At5g44140
GO:0003674 molecular_function F
ND
SceS000003463
SpoSPCC1322.16
GO:0000001 mitochondrion inheritance P
IMP
SceS000003463
GO:0001302 replicative cell aging P
IMP
SceS000003463
GO:0006457 protein folding P
IDA
SceS000003463
IPI
SceS000003463
ISS
SceS000003463
SpoSPCC1322.16
GO:0006950 response to stress P
IMP
AthAt4g28510
GO:0008150 biological_process P
ND
AthAt5g44140
At1g03860
At2g20530
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000003463
GO:0045861 negative regulation of proteolysis P
IMP
SceS000003463
IPI
SceS000003463
GO:0055114 oxidation reduction P
RCA
SceS000003463

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5263

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PHB2 GI:221307584
Pan troglodytes (Ptr) PHB2 GI:114643120
Canis familiaris (Cfa) PHB2 GI:73997722
Mus musculus (Mmu) Phb2
(MGI:102520)
GI:126723336 O35129
Rattus norvegicus (Rno) Phb2
(RGD:620203)
GI:61556754
Gallus gallus (Gga) PHB2 GI:118083342
Drosophila melanogaster (Dme) l(2)03709
(FBgn0010551)
GI:161077242
Anopheles gambiae (Aga) AgaP_AGAP009642 GI:158298506
Caenorhabditis elegans (Cel) phb-2
(CE40718;
WBGene00004015)
GI:193205005
Schizosaccharomyces pombe (Spo) SPCC1322.16 GI:19075644 O94550
Saccharomyces cerevisiae (Sce) PHB2
(S000003463)
GI:50593217
Kluyveromyces lactis (Kla) KLLA0E15818g GI:50309305
Eremothecium gossypii (Ego) AGOS_ADL141W GI:45187732
Magnaporthe grisea (Mgr) MGG_09886 GI:39964829
Neurospora crassa (Ncr) NCU03310.1 GI:32420605
Arabidopsis thaliana (Ath) ATPHB6 GI:145329190
Arabidopsis thaliana (Ath) ATPHB1 GI:15235317
Arabidopsis thaliana (Ath) ATPHB2 GI:42571331
Arabidopsis thaliana (Ath) ATPHB7 GI:15241424
Oryza sativa (Osa) Os03g0841700 GI:115456505
Oryza sativa (Osa) Os07g0262200 GI:115471453
Plasmodium falciparum (Pfa) PF10_0144 GI:124802284


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthATPHB2
GO:0005634 nucleus C
IDA
MmuMGI:102520
ISS
HsaPHB2
GO:0005739 mitochondrion C
IDA
AthATPHB2
ATPHB7
ATPHB1
ATPHB6
MmuMGI:102520
SceS000003463
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:102520
SceS000003463
ISS
HsaPHB2
SpoSPCC1322.16
GO:0005747 mitochondrial respiratory chain complex
I
C
IDA
AthATPHB2
ATPHB6
GO:0005773 vacuole C
IDA
AthATPHB2
GO:0005811 lipid particle C
IDA
DmeFBgn0010551
GO:0005886 plasma membrane C
IDA
AthATPHB1
ATPHB2
ATPHB6
GO:0009507 chloroplast C
IDA
AthATPHB2
GO:0009536 plastid C
IDA
AthATPHB2
GO:0016020 membrane C
IDA
AthATPHB7
ATPHB6
GO:0045271 respiratory chain complex I C
IDA
AthATPHB2
ATPHB1
ATPHB6
ATPHB7
GO:0003674 molecular_function F
ND
PfaPF10_0144
SceS000003463
SpoSPCC1322.16
GO:0005515 protein binding F
IPI
HsaPHB2
MmuMGI:102520
GO:0016566 specific transcriptional repressor
activity
F
IDA
HsaPHB2
MmuMGI:102520
GO:0030331 estrogen receptor binding F
NAS
HsaPHB2
GO:0000001 mitochondrion inheritance P
IMP
SceS000003463
GO:0000003 reproduction P
IMP
CelWBGene00004015
GO:0001302 replicative cell aging P
IMP
SceS000003463
GO:0006457 protein folding P
IDA
SceS000003463
IPI
SceS000003463
ISS
SceS000003463
SpoSPCC1322.16
GO:0006950 response to stress P
IMP
AthATPHB1
GO:0008150 biological_process P
ND
AthATPHB2
ATPHB6
ATPHB7
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004015
GO:0009987 cellular process P
ISS
PfaPF10_0144
GO:0010171 body morphogenesis P
IMP
CelWBGene00004015
GO:0016481 negative regulation of transcription P
IDA
MmuMGI:102520
NAS
HsaPHB2
GO:0033147 negative regulation of estrogen receptor signaling
pathway
P
IGI
MmuMGI:102520
IMP
MmuMGI:102520
GO:0033600 negative regulation of mammary gland epithelial
cell proliferation
P
IMP
MmuMGI:102520
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004015
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000003463
GO:0045861 negative regulation of proteolysis P
IMP
SceS000003463
IPI
SceS000003463
GO:0055114 oxidation reduction P
RCA
SceS000003463
GO:0060744 mammary gland branching involved in
thelarche
P
IMP
MmuMGI:102520
GO:0060749 mammary gland alveolus development P
IMP
MmuMGI:102520
GO:0060762 regulation of branching involved in mammary gland
duct morphogenesis
P
IMP
MmuMGI:102520

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1235

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga11835 ENSANGP00000022240
Anopheles gambiae (Aga) aga11837 ENSANGP00000027683
Anopheles gambiae (Aga) aga11836 ENSANGP00000029540
Ashbya gossypii (Ago) ago1600 ADL141W
Arabidopsis thaliana (Ath) ath325 At1g03860.1
Arabidopsis thaliana (Ath) ath327 At1g03860.3
Arabidopsis thaliana (Ath) ath8916 At2g20530.1
Arabidopsis thaliana (Ath) ath20881 At4g28510.1
Arabidopsis thaliana (Ath) ath26239 At5g44140.1
Caenorhabditis elegans (Cel) cel16290 T24H7.1
(CE40718;
WBGene00004015)
Candida glabrata (Cgl) cgl4361 CAGL0L06490g
Cryptococcus neoformans (Cne) cne1829 181.m08665
Dictyostelium discoideum (Ddi) ddi7633 DDB0185861
Debaryomyces hansenii (Dha) dha1314 DEHA0B14553g
Drosophila melanogaster (Dme) dme5942 CG15081-PA
(FBgn0010551)
Drosophila melanogaster (Dme) dme5941 CG15081-PB
(FBgn0010551)
Drosophila melanogaster (Dme) dme5940 CG15081-PC
(FBgn0010551)
Danio rerio (Dre) dre20401 ENSDARP00000025197
Danio rerio (Dre) dre20400 ENSDARP00000042055
(zgc:86841)
Q6DI14
Gallus gallus (Gga) gga1582 ENSGALP00000023446
(PHB2)
Q5ZMN3
Kluyveromyces lactis (Kla) kla3658 KLLA0E15818g
Mus musculus (Mmu) mmu22713 ENSMUSP00000004375
(MGI:102520)
O35129
Neurospora crassa (Ncr) ncr3207 NCU03310.2
Oryza sativa (Osa) osa3134 2001.m00082
Oryza sativa (Osa) osa26577 4127.m00167
Oryza sativa (Osa) osa47441 5779.m00051
Oryza sativa (Osa) osa66399 6893.m00129
Oryza sativa (Osa) osa87324 9229.m00152
Oryza sativa (Osa) osa87173 9545.m00133
Plasmodium falciparum (Pfa) pfa365 PF10_0144
Rattus norvegicus (Rno) rno22196 ENSRNOP00000017472
(RGD:620203)
Q5XIH7
Saccharomyces cerevisiae (Sce) sce2612 YGR231C
(S000003463)
Schizosaccharomyces pombe (Spo) spo4146 SPCC1322.16 O94550
Yarrowia lipolytica (Yli) yli1593 YALI0B20482g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt1g03860
GO:0005634 nucleus C
IDA
MmuMGI:102520
GO:0005739 mitochondrion C
IDA
AthAt2g20530
At1g03860
At4g28510
At5g44140
MmuMGI:102520
SceS000003463
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:102520
SceS000003463
ISS
SpoSPCC1322.16
GO:0005747 mitochondrial respiratory chain complex
I
C
IDA
AthAt2g20530
At1g03860
GO:0005773 vacuole C
IDA
AthAt1g03860
GO:0005811</