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Search term: YGR263C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SAY1
SGD link S000003495
Alternative ID YGR263C
Description Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum
Synonyms YGR263C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1515 AC-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Arylacetamide deacetylase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g19190 GI:15221975
Arabidopsis thaliana (Ath) At1g47480 GI:18401743
Arabidopsis thaliana (Ath) At1g49640 GI:15222791
Arabidopsis thaliana (Ath) At1g49650 GI:18402731
Arabidopsis thaliana (Ath) At1g49660 GI:15222795
Arabidopsis thaliana (Ath) At1g68620 GI:18409077
Arabidopsis thaliana (Ath) At2g03550 GI:15227669
Arabidopsis thaliana (Ath) At2g45600 GI:18406834
Arabidopsis thaliana (Ath) At2g45610 GI:15225521
Arabidopsis thaliana (Ath) At3g05120 GI:15229905
Arabidopsis thaliana (Ath) At3g27320 GI:15232134
Arabidopsis thaliana (Ath) At3g48690 GI:15228425
Arabidopsis thaliana (Ath) At3g48700 GI:15228426
Arabidopsis thaliana (Ath) At3g63010 GI:15229371
Arabidopsis thaliana (Ath) At5g06570 GI:15240090
Arabidopsis thaliana (Ath) At5g14310 GI:11290080
Arabidopsis thaliana (Ath) At5g16080 GI:15237267
Arabidopsis thaliana (Ath) At5g23530 GI:15237783
Arabidopsis thaliana (Ath) At5g27320 GI:15240483
Arabidopsis thaliana (Ath) At5g62180 GI:15241725
Caenorhabditis elegans (Cel) CE03271
(WBGene00009186)		 GI:17540028 Q19839
Caenorhabditis elegans (Cel) CE09443
(WBGene00017515)		 GI:17567059 Q94187
Caenorhabditis elegans (Cel) CE21882 GI:17565640
Homo sapiens (Hsa) Hs17438979 GI:17438979
Homo sapiens (Hsa) Hs17462343 GI:17462343
Homo sapiens (Hsa) Hs18545307 GI:18545307
Homo sapiens (Hsa) Hs20477603 GI:20477603
Homo sapiens (Hsa) Hs22045305 GI:22045305
Homo sapiens (Hsa) Hs4557227 GI:4557227
Saccharomyces cerevisiae (Sce) YGR263c
(S000003495)		 GI:6321702 P53324
Schizosaccharomyces pombe (Spo) SPAC1039.03 GI:19115906 Q9US38
Schizosaccharomyces pombe (Spo) SPAC4A8.06c GI:19114729 O14158
Schizosaccharomyces pombe (Spo) SPAPB1A11.02 GI:19114910 Q9HDX3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g06570
At1g47480
At5g27320
At2g45600
At5g62180
At2g45610
At3g48700
At1g19190
At5g16080
At1g49640
At3g63010
At2g03550
At1g49660
At1g68620
SpoSPAPB1A11.02
GO:0005634 nucleus C
IDA
AthAt3g05120
SpoSPAC1039.03
GO:0005737 cytoplasm C
IDA
AthAt3g05120
NAS
AthAt3g48690
GO:0005739 mitochondrion C
IDA
SpoSPAC4A8.06c
GO:0005783 endoplasmic reticulum C
IDA
SceS000003495
GO:0005788 endoplasmic reticulum lumen C
IDA
SceS000003495
GO:0005829 cytosol C
IDA
SpoSPAC1039.03
GO:0016021 integral to membrane C
IDA
SceS000003495
GO:0003674 molecular_function F
ND
SpoSPAC1039.03
SPAC4A8.06c
SPAPB1A11.02
GO:0004091 carboxylesterase activity F
IDA
AthAt5g23530
At1g49660
At3g48690
GO:0034084 steryl deacetylase activity F
IDA
SceS000003495
IMP
SceS000003495
GO:0008150 biological_process P
ND
SpoSPAC1039.03
SPAC4A8.06c
SPAPB1A11.02
GO:0009636 response to toxin P
IMP
SceS000003495
GO:0009739 response to gibberellin stimulus P
IEP
AthAt3g05120
At3g63010
IGI
AthAt3g63010
At5g27320
At3g05120
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009186
GO:0009860 pollen tube growth P
IEP
AthAt5g23530
GO:0009939 positive regulation of gibberellic acid mediated
signaling pathway		 P
IGI
AthAt3g05120
At5g27320
At3g63010
GO:0010325 raffinose family oligosaccharide biosynthetic
process		 P
IGI
AthAt3g63010
At3g05120
At5g27320
GO:0010476 gibberellin mediated signaling
pathway		 P
IGI
AthAt5g27320
At3g05120
At3g63010
GO:0016125 sterol metabolic process P
IMP
SceS000003495
GO:0018991 oviposition P
IMP
CelWBGene00009186
GO:0034210 sterol deacetylation P
IMP
SceS000003495
GO:0048444 floral organ morphogenesis P
IGI
AthAt5g27320
At3g05120
At3g63010

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13277

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1788 ADR047W
Candida glabrata (Cgl) cgl1593 CAGL0F08437g
Cryptococcus neoformans (Cne) cne411 162.m04531
Debaryomyces hansenii (Dha) dha4962 DEHA0F12991g
Debaryomyces hansenii (Dha) dha4963 DEHA0F13013g
Debaryomyces hansenii (Dha) dha4965 DEHA0F13057g
Kluyveromyces lactis (Kla) kla3989 KLLA0E23100g
Saccharomyces cerevisiae (Sce) sce2645 YGR263C
(S000003495)
Schizosaccharomyces pombe (Spo) spo2557 SPBPB2B2.02 Q9HDV1


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBPB2B2.02
GO:0005783 endoplasmic reticulum C
IDA
SceS000003495
SpoSPBPB2B2.02
GO:0005788 endoplasmic reticulum lumen C
IDA
SceS000003495
GO:0016021 integral to membrane C
IDA
SceS000003495
GO:0003674 molecular_function F
ND
SpoSPBPB2B2.02
GO:0034084 steryl deacetylase activity F
IDA
SceS000003495
IMP
SceS000003495
GO:0009636 response to toxin P
IMP
SceS000003495
GO:0016125 sterol metabolic process P
IMP
SceS000003495
GO:0033554 cellular response to stress P
IEP
SpoSPBPB2B2.02
GO:0034210 sterol deacetylation P
IMP
SceS000003495

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBPB2B2.02
(Q9HDV1)		 YGR263C
(S000003495)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBPB2B2.02
GO:0005783 endoplasmic reticulum C
IDA
SceS000003495
SpoSPBPB2B2.02
GO:0005788 endoplasmic reticulum lumen C
IDA
SceS000003495
GO:0016021 integral to membrane C
IDA
SceS000003495
GO:0003674 molecular_function F
ND
SpoSPBPB2B2.02
GO:0034084 steryl deacetylase activity F
IDA
SceS000003495
IMP
SceS000003495
GO:0009636 response to toxin P
IMP
SceS000003495
GO:0016125 sterol metabolic process P
IMP
SceS000003495
GO:0033554 cellular response to stress P
IEP
SpoSPBPB2B2.02
GO:0034210 sterol deacetylation P
IMP
SceS000003495

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s.khadayate@ucl.ac.uk