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Search term: YGR264C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MES1
SGD link S000003496
Alternative ID YGR264C
Description Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
Synonyms YGR264C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1247 AC-HYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Methionyl-tRNA synthetase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g13780_1 GI:15236350
Arabidopsis thaliana (Ath) At5g02680 GI:15241914
Caenorhabditis elegans (Cel) CE06007_1 GI:17540794 Q20970
Homo sapiens (Hsa) Hs14043022_2
(MARS)		 GI:14043022 P56192
Homo sapiens (Hsa) Hs22059730 GI:22059730
Saccharomyces cerevisiae (Sce) YGR264c
(S000003496)		 GI:6321704 P00958
Schizosaccharomyces pombe (Spo) SPBC17A3.04c GI:19112378 Q9UUF2
Encephalitozoon cuniculi (Ecu) ECU11g0890 GI:19074889 Q8SQW5
Arabidopsis thaliana (Ath) At4g13780_1 GI:15236350
Arabidopsis thaliana (Ath) At5g02680 GI:15241914
Caenorhabditis elegans (Cel) CE06007_1 GI:17540794 Q20970
Homo sapiens (Hsa) Hs14043022_2
(MARS)		 GI:14043022 P56192
Homo sapiens (Hsa) Hs22059730 GI:22059730
Saccharomyces cerevisiae (Sce) YGR264c
(S000003496)		 GI:6321704 P00958
Schizosaccharomyces pombe (Spo) SPBC17A3.04c GI:19112378 Q9UUF2
Encephalitozoon cuniculi (Ecu) ECU11g0890 GI:19074889 Q8SQW5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
HsaMARS
SceS000003496
ISS
SpoSPBC17A3.04c
GO:0005829 cytosol C
EXP
HsaMARS
IDA
SpoSPBC17A3.04c
TAS
AthAt4g13780
GO:0017102 methionyl glutamyl tRNA synthetase
complex		 C
IDA
SceS000003496
GO:0004825 methionine-tRNA ligase activity F
EXP
HsaMARS
IDA
SceS000003496
ISS
AthAt4g13780
SpoSPBC17A3.04c
GO:0005515 protein binding F
IPI
HsaMARS
GO:0000003 reproduction P
IMP
CelWBGene00003415
GO:0002119 nematode larval development P
IMP
CelWBGene00003415
GO:0006417 regulation of translation P
RCA
SceS000003496
GO:0006431 methionyl-tRNA aminoacylation P
IC
SpoSPBC17A3.04c
IDA
SceS000003496
ISS
AthAt4g13780
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003415
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003415
GO:0040007 growth P
IMP
CelWBGene00003415
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003415
GO:0046686 response to cadmium ion P
IEP
AthAt4g13780

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
90878

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MARS GI:14043022 P56192
Pan troglodytes (Ptr) MARS GI:114644161
Canis familiaris (Cfa) MARS GI:73968523
Mus musculus (Mmu) Mars
(MGI:1345633)		 GI:51491852 Q68FL6
Gallus gallus (Gga) MARS GI:118110948
Drosophila melanogaster (Dme) CG15100
(FBgn0034401)		 GI:24655311
Anopheles gambiae (Aga) AgaP_AGAP007891 GI:158297351
Caenorhabditis elegans (Cel) mrs-1
(CE06007;
WBGene00003415)		 GI:17540794 Q20970
Schizosaccharomyces pombe (Spo) SPBC17A3.04c GI:19112378 Q9UUF2
Saccharomyces cerevisiae (Sce) MES1
(S000003496)		 GI:6321704 P00958
Kluyveromyces lactis (Kla) KLLA0A09647g GI:50302967
Eremothecium gossypii (Ego) AGOS_AGR332C GI:45201428
Magnaporthe grisea (Mgr) MGG_01046 GI:39973615
Neurospora crassa (Ncr) NCU07451.1 GI:32414515
Arabidopsis thaliana (Ath) AT4G13780 GI:15236350
Oryza sativa (Osa) Os06g0508700 GI:115468260


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
ISO
MmuMGI:1345633
GO:0005737 cytoplasm C
IDA
HsaMARS
SceS000003496
ISO
MmuMGI:1345633
ISS
SpoSPBC17A3.04c
GO:0005739 mitochondrion C
IDA
MmuMGI:1345633
GO:0005829 cytosol C
EXP
HsaMARS
IDA
SpoSPBC17A3.04c
TAS
AthAt4g13780
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0034401
GO:0017102 methionyl glutamyl tRNA synthetase
complex		 C
IDA
SceS000003496
GO:0004825 methionine-tRNA ligase activity F
EXP
HsaMARS
IDA
SceS000003496
ISO
MmuMGI:1345633
ISS
AthAt4g13780
DmeFBgn0034401
SpoSPBC17A3.04c
GO:0005515 protein binding F
IPI
HsaMARS
GO:0000003 reproduction P
IMP
CelWBGene00003415
GO:0002119 nematode larval development P
IMP
CelWBGene00003415
GO:0006417 regulation of translation P
RCA
SceS000003496
GO:0006431 methionyl-tRNA aminoacylation P
IC
SpoSPBC17A3.04c
IDA
SceS000003496
ISO
MmuMGI:1345633
ISS
AthAt4g13780
DmeFBgn0034401
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003415
GO:0009303 rRNA transcription P
ISO
MmuMGI:1345633
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003415
GO:0040007 growth P
IMP
CelWBGene00003415
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003415
GO:0046686 response to cadmium ion P
IEP
AthAt4g13780

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2000

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9824 ENSANGP00000010004
Ashbya gossypii (Ago) ago4643 AGR332C
Arabidopsis thaliana (Ath) ath19143 At4g13780.1
Caenorhabditis elegans (Cel) cel10853 F58B3.5
(CE06007;
WBGene00003415)
Candida glabrata (Cgl) cgl1594 CAGL0F08459g
Cryptococcus neoformans (Cne) cne997 163.m06483
Dictyostelium discoideum (Ddi) ddi12337 DDB0231297
Debaryomyces hansenii (Dha) dha6662 DEHA0G21549g
Drosophila melanogaster (Dme) dme5949 CG15100-PA
(FBgn0034401)
Escherichia coli (Eco) eco2049 16130052
Encephalitozoon cuniculi (Ecu) ecu977 19074889
Takifugu rubripes (Fru) fru13133 SINFRUP00000141534
Homo sapiens (Hsa) hsa7742 ENSP00000262027
(MARS)		 P56192
Kluyveromyces lactis (Kla) kla418 KLLA0A09647g
Mus musculus (Mmu) mmu2964 ENSMUSP00000037446
(MGI:1345633)		 Q68FL6
Neurospora crassa (Ncr) ncr7253 NCU07451.2
Oryza sativa (Osa) osa2321 1943.m00184
Oryza sativa (Osa) osa16494 3136.m00154
Oryza sativa (Osa) osa16511 3136.m00194
Rattus norvegicus (Rno) rno26891 ENSRNOP00000034945
(RGD:1305321)
Saccharomyces cerevisiae (Sce) sce2646 YGR264C
(S000003496)
Schizosaccharomyces pombe (Spo) spo914 SPBC17A3.04c Q9UUF2
Yarrowia lipolytica (Yli) yli6566 YALI0F29843g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
ISO
MmuMGI:1345633
GO:0005737 cytoplasm C
IDA
SceS000003496
ISO
MmuMGI:1345633
ISS
SpoSPBC17A3.04c
GO:0005739 mitochondrion C
IDA
MmuMGI:1345633
GO:0005829 cytosol C
IDA
SpoSPBC17A3.04c
TAS
AthAt4g13780
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0034401
GO:0017102 methionyl glutamyl tRNA synthetase
complex		 C
IDA
SceS000003496
GO:0004825 methionine-tRNA ligase activity F
IDA
SceS000003496
ISO
MmuMGI:1345633
ISS
AthAt4g13780
DmeFBgn0034401
SpoSPBC17A3.04c
GO:0000003 reproduction P
IMP
CelWBGene00003415
GO:0002119 nematode larval development P
IMP
CelWBGene00003415
GO:0006417 regulation of translation P
RCA
SceS000003496
GO:0006431 methionyl-tRNA aminoacylation P
IC
SpoSPBC17A3.04c
IDA
SceS000003496
ISO
MmuMGI:1345633
ISS
AthAt4g13780
DmeFBgn0034401
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003415
GO:0009303 rRNA transcription P
ISO
MmuMGI:1345633
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003415
GO:0040007 growth P
IMP
CelWBGene00003415
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003415
GO:0046686 response to cadmium ion P
IEP
AthAt4g13780

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC17A3.04c
(Q9UUF2)		 YGR264C
(S000003496)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000003496
ISS
SpoSPBC17A3.04c
GO:0005829 cytosol C
IDA
SpoSPBC17A3.04c
GO:0017102 methionyl glutamyl tRNA synthetase
complex		 C
IDA
SceS000003496
GO:0004825 methionine-tRNA ligase activity F
IDA
SceS000003496
ISS
SpoSPBC17A3.04c
GO:0006417 regulation of translation P
RCA
SceS000003496
GO:0006431 methionyl-tRNA aminoacylation P
IC
SpoSPBC17A3.04c
IDA
SceS000003496

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GO info in one table:

s.khadayate@ucl.ac.uk