YOGY Home YOGY Help

Search term: YGR280C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PXR1
SGD link S000003512
Alternative ID YGR280C
Description Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
Synonyms YGR280C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2809 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Telomerase elongation inhibitor/RNA maturation protein PINX1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63980 GI:18407934
Caenorhabditis elegans (Cel) CE03704
(WBGene00011966)
GI:17536425 Q22705
Drosophila melanogaster (Dme) 7302027 GI:7302027
Drosophila melanogaster (Dme) 7302356 GI:7302356 A1ZBW6
Homo sapiens (Hsa) Hs18549312 GI:18549312
Homo sapiens (Hsa) Hs20551919 GI:20551919
Homo sapiens (Hsa) Hs16975486 GI:16975486
Saccharomyces cerevisiae (Sce) YGR280c
(S000003512)
GI:6321719 P53335
Schizosaccharomyces pombe (Spo) SPAC1952.02 GI:19115717 Q9UUK4
Schizosaccharomyces pombe (Spo) SPAC890.05 GI:19115735 Q9URX9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
ISS
AthAt1g63980
GO:0005634 nucleus C
IDA
SpoSPAC890.05
GO:0005654 nucleoplasm C
IDA
SceS000003512
GO:0005730 nucleolus C
IDA
SceS000003512
SpoSPAC1952.02
ISS
SpoSPAC890.05
SPAC1952.02
GO:0003676 nucleic acid binding F
ISS
AthAt1g63980
GO:0003723 RNA binding F
ISS
SpoSPAC890.05
SPAC1952.02
GO:0010521 telomerase inhibitor activity F
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0000494 box C/D snoRNA 3'-end processing P
IMP
SceS000003512
GO:0006364 rRNA processing P
RCA
SceS000003512
GO:0008150 biological_process P
ND
AthAt1g63980
GO:0016072 rRNA metabolic process P
RCA
SceS000003512
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC890.05
SPAC1952.02

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31531

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PINX1 GI:148747556
Pan troglodytes (Ptr) LOC463987 GI:114623561
Canis familiaris (Cfa) LOC607910 GI:73993784
Mus musculus (Mmu) 2610028A01Rik
(MGI:1919650)
GI:18129616 Q9CZX5
Rattus norvegicus (Rno) Pinx1 GI:62661626
Gallus gallus (Gga) PINX1 GI:118089118
Drosophila melanogaster (Dme) CG11180
(FBgn0034528)
GI:24656362
Anopheles gambiae (Aga) AgaP_AGAP008951 GI:158299616
Caenorhabditis elegans (Cel) T23G7.3
(CE03704;
WBGene00011966)
GI:17536425 Q22705
Saccharomyces cerevisiae (Sce) PXR1
(S000003512)
GI:6321719 P53335
Kluyveromyces lactis (Kla) KLLA0C14135g GI:50305743
Eremothecium gossypii (Ego) AGOS_AGL350C GI:45200747
Magnaporthe grisea (Mgr) MGG_09279 GI:39958695
Neurospora crassa (Ncr) NCU02528.1 GI:32422567


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
HsaPINX1
GO:0000776 kinetochore C
IDA
HsaPINX1
GO:0000781 chromosome, telomeric region C
IDA
MmuMGI:1919650
GO:0005654 nucleoplasm C
IDA
SceS000003512
GO:0005730 nucleolus C
IDA
HsaPINX1
MmuMGI:1919650
SceS000003512
GO:0005819 spindle C
IDA
HsaPINX1
GO:0005515 protein binding F
IPI
HsaPINX1
MmuMGI:1919650
GO:0010521 telomerase inhibitor activity F
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
TAS
HsaPINX1
GO:0070034 telomeric RNA binding F
IDA
HsaPINX1
GO:0000494 box C/D snoRNA 3'-end processing P
IMP
SceS000003512
GO:0006364 rRNA processing P
RCA
SceS000003512
GO:0007004 telomere maintenance via telomerase P
IDA
MmuMGI:1919650
GO:0007080 mitotic metaphase plate congression P
IMP
HsaPINX1
GO:0008285 negative regulation of cell proliferation P
NAS
HsaPINX1
GO:0016072 rRNA metabolic process P
RCA
SceS000003512
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0051972 regulation of telomerase activity P
TAS
HsaPINX1

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2181

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga11038 ENSANGP00000006479
Ashbya gossypii (Ago) ago3962 AGL350C
Arabidopsis thaliana (Ath) ath5607 At1g63980.1
Caenorhabditis elegans (Cel) cel16179 T23G7.3
(CE03704;
WBGene00011966)
Candida glabrata (Cgl) cgl1637 CAGL0G00264g
Cryptococcus neoformans (Cne) cne1748 164.m02130
Dictyostelium discoideum (Ddi) ddi3058 DDB0167914
Dictyostelium discoideum (Ddi) ddi11103 DDB0191976
Dictyostelium discoideum (Ddi) ddi4315 DDB0215282
Debaryomyces hansenii (Dha) dha1979 DEHA0C12419g
Drosophila melanogaster (Dme) dme6195 CG11180-PA
(FBgn0034528)
Danio rerio (Dre) dre12254 ENSDARP00000031264
(pinx1)
Q5QGN4
Takifugu rubripes (Fru) fru27084 SINFRUP00000133862
Gallus gallus (Gga) gga16205 ENSGALP00000026820
(PINX1)
Homo sapiens (Hsa) hsa29898 ENSP00000318966
(SOX7)
Q96BK5-1
Homo sapiens (Hsa) hsa29899 ENSP00000346908
(SOX7)
B4DKV0
Kluyveromyces lactis (Kla) kla1831 KLLA0C14135g
Mus musculus (Mmu) mmu8365 ENSMUSP00000022528
(MGI:1919650)
Q9CZX5
Neurospora crassa (Ncr) ncr2449 NCU02528.2
Plasmodium falciparum (Pfa) pfa1054 PF11_0109
Rattus norvegicus (Rno) rno11548 ENSRNOP00000016027
(RGD:1566025)
A4L691
Saccharomyces cerevisiae (Sce) sce2664 YGR280C
(S000003512)
Schizosaccharomyces pombe (Spo) spo2260 SPAC890.05 Q9URX9
Yarrowia lipolytica (Yli) yli985 YALI0B05962g
Yarrowia lipolytica (Yli) yli5987 YALI0F15235g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
MmuMGI:1919650
GO:0005622 intracellular C
ISS
AthAt1g63980
GO:0005634 nucleus C
IDA
SpoSPAC890.05
GO:0005654 nucleoplasm C
IDA
SceS000003512
GO:0005730 nucleolus C
IDA
MmuMGI:1919650
SceS000003512
ISS
SpoSPAC890.05
GO:0003676 nucleic acid binding F
ISS
AthAt1g63980
GO:0003723 RNA binding F
ISS
SpoSPAC890.05
GO:0005515 protein binding F
IPI
MmuMGI:1919650
GO:0010521 telomerase inhibitor activity F
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0000494 box C/D snoRNA 3'-end processing P
IMP
SceS000003512
GO:0006364 rRNA processing P
RCA
SceS000003512
GO:0007004 telomere maintenance via telomerase P
IDA
MmuMGI:1919650
GO:0008150 biological_process P
ND
AthAt1g63980
GO:0016072 rRNA metabolic process P
RCA
SceS000003512
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC890.05

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC890.05
(Q9URX9)
YGR280C
(S000003512)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC890.05
GO:0005654 nucleoplasm C
IDA
SceS000003512
GO:0005730 nucleolus C
IDA
SceS000003512
ISS
SpoSPAC890.05
GO:0003723 RNA binding F
ISS
SpoSPAC890.05
GO:0010521 telomerase inhibitor activity F
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0000494 box C/D snoRNA 3'-end processing P
IMP
SceS000003512
GO:0006364 rRNA processing P
RCA
SceS000003512
GO:0016072 rRNA metabolic process P
RCA
SceS000003512
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IGI
SceS000003512
IMP
SceS000003512
IPI
SceS000003512
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC890.05

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk