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Search term: YHL003C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LAG1
SGD link S000000995
Alternative ID YHL003C
Description Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p
Synonyms YHL003C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1607 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Protein transporter of the TRAM (translocating chain-associating membrane) superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g13580 GI:15222889
Arabidopsis thaliana (Ath) At3g19260 GI:15230323
Arabidopsis thaliana (Ath) At3g25540 GI:18404559
Caenorhabditis elegans (Cel) CE04706 GI:17568639
Caenorhabditis elegans (Cel) CE20184
(WBGene00006505)		 GI:17509707 Q9XWE9
Caenorhabditis elegans (Cel) CE27675
(WBGene00002043)		 GI:17541106 Q9GYR9
Drosophila melanogaster (Dme) 7290690 GI:7290690
Homo sapiens (Hsa) Hs11641421
(LASS1)		 GI:11641421 P27544
Homo sapiens (Hsa) Hs17461921 GI:17461921
Homo sapiens (Hsa) Hs22044511 GI:22044511
Homo sapiens (Hsa) Hs20481895 GI:20481895
Homo sapiens (Hsa) Hs20532972 GI:20532972
Homo sapiens (Hsa) Hs20550645 GI:20550645
Homo sapiens (Hsa) Hs13375717 GI:13375717
Homo sapiens (Hsa) Hs9937998 GI:9937998
Saccharomyces cerevisiae (Sce) YHL003c
(S000000995)		 GI:6321784 P38703
Saccharomyces cerevisiae (Sce) YKL008c
(S000001491)		 GI:6322844 P28496
Schizosaccharomyces pombe (Spo) SPAC1A6.09c GI:19114113 P78970
Schizosaccharomyces pombe (Spo) SPBC3E7.15c GI:19112894 O59735
Encephalitozoon cuniculi (Ecu) ECU08g1350 GI:19173461 Q8SRA0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g13580
At3g25540
At3g19260
SceS000000995
SpoSPAC1A6.09c
ISS
SpoSPAC1A6.09c
SPBC3E7.15c
TAS
SceS000001491
GO:0005789 endoplasmic reticulum membrane C
ISS
CelWBGene00002043
GO:0005792 microsome C
ISS
HsaLASS1
GO:0005794 Golgi apparatus C
IDA
AthAt3g25540
At3g19260
GO:0005886 plasma membrane C
IDA
AthAt3g19260
At3g25540
GO:0030176 integral to endoplasmic reticulum
membrane		 C
NAS
SpoSPBC3E7.15c
SPAC1A6.09c
GO:0003674 molecular_function F
ND
AthAt3g19260
At3g25540
At1g13580
HsaLASS1
GO:0050291 sphingosine N-acyltransferase activity F
IDA
SceS000001491
S000000995
IMP
SceS000001491
S000000995
ISS
HsaLASS1
SpoSPAC1A6.09c
SPBC3E7.15c
GO:0001302 replicative cell aging P
IEP
SceS000000995
IGI
SceS000001491
IMP
SceS000000995
GO:0002238 response to molecule of fungal
origin		 P
IMP
AthAt3g19260
GO:0007009 plasma membrane organization P
IMP
SpoSPBC3E7.15c
GO:0007035 vacuolar acidification P
IGI
SpoSPAC1A6.09c
IMP
SpoSPBC3E7.15c
GO:0007568 aging P
ISS
CelWBGene00002043
GO:0009636 response to toxin P
IGI
SpoSPBC3E7.15c
IMP
SpoSPAC1A6.09c
GO:0010043 response to zinc ion P
IMP
SpoSPBC3E7.15c
GO:0010467 gene expression P
IMP
CelWBGene00006505
WBGene00002043
GO:0010849 regulation of proton-transporting ATPase activity,
rotational mechanism		 P
IMP
SpoSPBC3E7.15c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000995
GO:0019915 lipid storage P
IMP
CelWBGene00006505
GO:0034605 cellular response to heat P
IMP
SpoSPBC3E7.15c
GO:0042493 response to drug P
IGI
SpoSPAC1A6.09c
SPBC3E7.15c
IMP
SpoSPAC1A6.09c
SPBC3E7.15c
GO:0046513 ceramide biosynthetic process P
IDA
SceS000000995
S000001491
IMP
SceS000001491
S000000995
ISS
CelWBGene00002043
HsaLASS1
SpoSPAC1A6.09c
SPBC3E7.15c
GO:0051592 response to calcium ion P
IMP
SpoSPBC3E7.15c
GO:0070072 vacuolar proton-transporting V-type ATPase complex
assembly		 P
ISS
SpoSPBC3E7.15c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101614

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) lac1
(SPBC3E7.15c)		 GI:19112894 O59735
Saccharomyces cerevisiae (Sce) LAG1
(S000000995)		 GI:6321784 P38703
Saccharomyces cerevisiae (Sce) LAC1
(S000001491)		 GI:6322844 P28496
Kluyveromyces lactis (Kla) KLLA0B13497g GI:50304365
Eremothecium gossypii (Ego) AGOS_ABR009W GI:45185238
Magnaporthe grisea (Mgr) MGG_05189 GI:39940102
Neurospora crassa (Ncr) NCU00008.1 GI:32402962


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000000995
ISS
SpoSPBC3E7.15c
TAS
SceS000001491
GO:0030176 integral to endoplasmic reticulum
membrane		 C
NAS
SpoSPBC3E7.15c
GO:0050291 sphingosine N-acyltransferase activity F
IDA
SceS000001491
S000000995
IMP
SceS000001491
S000000995
ISS
SpoSPBC3E7.15c
GO:0001302 replicative cell aging P
IEP
SceS000000995
IGI
SceS000001491
IMP
SceS000000995
GO:0007009 plasma membrane organization P
IMP
SpoSPBC3E7.15c
GO:0007035 vacuolar acidification P
IMP
SpoSPBC3E7.15c
GO:0009636 response to toxin P
IGI
SpoSPBC3E7.15c
GO:0010043 response to zinc ion P
IMP
SpoSPBC3E7.15c
GO:0010849 regulation of proton-transporting ATPase activity,
rotational mechanism		 P
IMP
SpoSPBC3E7.15c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000995
GO:0034605 cellular response to heat P
IMP
SpoSPBC3E7.15c
GO:0042493 response to drug P
IGI
SpoSPBC3E7.15c
IMP
SpoSPBC3E7.15c
GO:0046513 ceramide biosynthetic process P
IDA
SceS000000995
S000001491
IMP
SceS000001491
S000000995
ISS
SpoSPBC3E7.15c
GO:0051592 response to calcium ion P
IMP
SpoSPBC3E7.15c
GO:0070072 vacuolar proton-transporting V-type ATPase complex
assembly		 P
ISS
SpoSPBC3E7.15c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_130

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3879 ENSANGP00000012836
Ashbya gossypii (Ago) ago600 ABR009W
Ashbya gossypii (Ago) ago1535 ADL206W
Arabidopsis thaliana (Ath) ath1430 At1g13580.1
Arabidopsis thaliana (Ath) ath14203 At3g19260.1
Arabidopsis thaliana (Ath) ath14870 At3g25540.1
Caenorhabditis elegans (Cel) cel1664 C09G4.1
(CE27675;
WBGene00002043)
Caenorhabditis elegans (Cel) cel11728 K02G10.6a
Caenorhabditis elegans (Cel) cel11729 K02G10.6b
Candida glabrata (Cgl) cgl3639 CAGL0K02739g
Candida glabrata (Cgl) cgl5103 CAGL0M10219g
Cryptococcus neoformans (Cne) cne3354 167.m05834
Cryptococcus neoformans (Cne) cne3241 167.m05835
Cryptococcus neoformans (Cne) cne4654 186.m03498
Dictyostelium discoideum (Ddi) ddi12578 DDB0230136
Debaryomyces hansenii (Dha) dha450 DEHA0A10109g
Debaryomyces hansenii (Dha) dha4175 DEHA0E21087g
Drosophila melanogaster (Dme) dme16693 CG3576-PA
(FBgn0040918)
Drosophila melanogaster (Dme) dme16694 CG3576-PB
(FBgn0040918)
Danio rerio (Dre) dre14113 ENSDARP00000002973
(zgc:63908)		 Q7T3F1
Danio rerio (Dre) dre30179 ENSDARP00000024504
(LOC566164)
Danio rerio (Dre) dre9895 ENSDARP00000038937
Danio rerio (Dre) dre14114 ENSDARP00000040718
Danio rerio (Dre) dre30451 ENSDARP00000042193
(trh1)		 Q1L8N1
Encephalitozoon cuniculi (Ecu) ecu292 19173461
Takifugu rubripes (Fru) fru27672 SINFRUP00000127317
Takifugu rubripes (Fru) fru18131 SINFRUP00000131467
Takifugu rubripes (Fru) fru12276 SINFRUP00000133730
Takifugu rubripes (Fru) fru19452 SINFRUP00000134993
Takifugu rubripes (Fru) fru22993 SINFRUP00000138493
Takifugu rubripes (Fru) fru130 SINFRUP00000148342
Takifugu rubripes (Fru) fru26845 SINFRUP00000150005
Takifugu rubripes (Fru) fru131 SINFRUP00000168497
Takifugu rubripes (Fru) fru27673 SINFRUP00000177351
Gallus gallus (Gga) gga13944 ENSGALP00000000406
(LASS4)
Gallus gallus (Gga) gga13945 ENSGALP00000000407
Gallus gallus (Gga) gga13961 ENSGALP00000000552
(LASS4)
Gallus gallus (Gga) gga13962 ENSGALP00000000553
Gallus gallus (Gga) gga24187 ENSGALP00000009966
(LASS5)
Gallus gallus (Gga) gga21598 ENSGALP00000017712
(LASS6)
Homo sapiens (Hsa) hsa15520 ENSP00000251363
(LASS4)		 Q9HA82
Homo sapiens (Hsa) hsa1974 ENSP00000271688
(LASS2)		 Q96G23
Homo sapiens (Hsa) hsa18812 ENSP00000306579
(LASS6)		 Q6ZMG9
Homo sapiens (Hsa) hsa7473 ENSP00000325485
(LASS5)		 Q8N5B7
Homo sapiens (Hsa) hsa1972 ENSP00000337842
(LASS2)		 Q5SZE6
Homo sapiens (Hsa) hsa1973 ENSP00000355020
(LASS2)		 Q5SZE4
Kluyveromyces lactis (Kla) kla1130 KLLA0B13497g
Kluyveromyces lactis (Kla) kla3317 KLLA0E08129g
Mus musculus (Mmu) mmu25573 ENSMUSP00000008350
(MGI:1914510)		 Q9D6J1
Mus musculus (Mmu) mmu17142 ENSMUSP00000015858
(MGI:1924143)		 Q924Z4
Mus musculus (Mmu) mmu9657 ENSMUSP00000023762
(MGI:1919199)		 Q9D6K9-1
Mus musculus (Mmu) mmu14711 ENSMUSP00000028426
(MGI:2442564)		 Q8C172
Mus musculus (Mmu) mmu24145 ENSMUSP00000032721
Mus musculus (Mmu) mmu9658 ENSMUSP00000066672
Neurospora crassa (Ncr) ncr8 NCU00008.2
Neurospora crassa (Ncr) ncr2392 NCU02468.2
Oryza sativa (Osa) osa5714 2426.m00104
Oryza sativa (Osa) osa25156 3838.m00156
Oryza sativa (Osa) osa39086 4916.m00073
Oryza sativa (Osa) osa47874 5795.m00184
Oryza sativa (Osa) osa57240 6405.m00164
Oryza sativa (Osa) osa62015 6666.m00096
Oryza sativa (Osa) osa77891 7331.m00103
Oryza sativa (Osa) osa78712 7387.m00080
Plasmodium falciparum (Pfa) pfa1254 PF14_0034
Plasmodium falciparum (Pfa) pfa3532 PFE0405c
Rattus norvegicus (Rno) rno7892 ENSRNOP00000001418
(RGD:1309303)
Rattus norvegicus (Rno) rno27751 ENSRNOP00000026223
(RGD:1311597)		 B2RYI9
Rattus norvegicus (Rno) rno16605 ENSRNOP00000028699
(RGD:1310059)
Rattus norvegicus (Rno) rno18719 ENSRNOP00000035208
(RGD:727864)
Rattus norvegicus (Rno) rno27752 ENSRNOP00000040285
(RGD:1311597)
Rattus norvegicus (Rno) rno7896 ENSRNOP00000043683
Rattus norvegicus (Rno) rno7897 ENSRNOP00000045092
Saccharomyces cerevisiae (Sce) sce2686 YHL003C
(S000000995)
Saccharomyces cerevisiae (Sce) sce3670 YKL008C
(S000001491)
Schizosaccharomyces pombe (Spo) spo1359 SPAC1A6.09c P78970
Schizosaccharomyces pombe (Spo) spo4407 SPBC3E7.15c O59735
Yarrowia lipolytica (Yli) yli2870 YALI0D04026g
Yarrowia lipolytica (Yli) yli5615 YALI0F06424g