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Search term: YHL010C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ETP1
SGD link S000001002
Alternative ID YHL010C
Description Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences
Synonyms YHL010C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0804 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Cytoplasmic Zn-finger protein BRAP2 (BRCA1 associated protein)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g26000 GI:15225236
Arabidopsis thaliana (Ath) At2g27160 GI:15225853
Arabidopsis thaliana (Ath) At2g42160 GI:15227893
Caenorhabditis elegans (Cel) CE28903
(WBGene00017144)
GI:17532837 Q95QN6
Drosophila melanogaster (Dme) 7300491 GI:7300491
Homo sapiens (Hsa) Hs10800417 GI:10800417
Saccharomyces cerevisiae (Sce) YHL010c
(S000001002)
GI:6321777 P38748
Schizosaccharomyces pombe (Spo) SPAC16E8.13 GI:19115138 O13747
Arabidopsis thaliana (Ath) At2g26000 GI:15225236
Arabidopsis thaliana (Ath) At2g27160 GI:15225853
Arabidopsis thaliana (Ath) At2g42160 GI:15227893
Caenorhabditis elegans (Cel) CE28903
(WBGene00017144)
GI:17532837 Q95QN6
Drosophila melanogaster (Dme) 7300491 GI:7300491
Homo sapiens (Hsa) Hs10800417 GI:10800417
Saccharomyces cerevisiae (Sce) YHL010c
(S000001002)
GI:6321777 P38748
Schizosaccharomyces pombe (Spo) SPAC16E8.13 GI:19115138 O13747


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000001002
GO:0005829 cytosol C
IDA
SpoSPAC16E8.13
GO:0003674 molecular_function F
ND
AthAt2g27160
GO:0003824 catalytic activity F
ISS
AthAt2g42160
At2g26000
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC16E8.13
GO:0008139 nuclear localization sequence binding F
IDA
SceS000001002
GO:0008270 zinc ion binding F
ISS
SpoSPAC16E8.13
GO:0043130 ubiquitin binding F
IDA
SceS000001002
GO:0008150 biological_process P
ND
AthAt2g27160
GO:0016567 protein ubiquitination P
ISS
SpoSPAC16E8.13
GO:0045471 response to ethanol P
IMP
SceS000001002

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4926

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) BRAP GI:188497705
Pan troglodytes (Ptr) BRAP GI:114647004
Canis familiaris (Cfa) BRAP GI:73995208
Mus musculus (Mmu) Brap
(MGI:1919649)
GI:70608139 Q99MP8
Gallus gallus (Gga) BRAP GI:118098528
Drosophila melanogaster (Dme) CG5555
(FBgn0038686)
GI:21356581
Anopheles gambiae (Aga) AgaP_AGAP002128 GI:158301172
Caenorhabditis elegans (Cel) EEED8.16
(CE28903;
WBGene00017144)
GI:17532837 Q95QN6
Schizosaccharomyces pombe (Spo) SPAC16E8.13 GI:19115138 O13747
Saccharomyces cerevisiae (Sce) YHL010C
(S000001002)
GI:6321777 P38748
Kluyveromyces lactis (Kla) KLLA0F25740g GI:50312385
Eremothecium gossypii (Ego) AGOS_AGL079C GI:45201017
Arabidopsis thaliana (Ath) AT2G26000 GI:42569332
Oryza sativa (Osa) Os02g0182900 GI:115444645


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IDA
HsaBRAP
ISO
MmuMGI:1919649
GO:0005575 cellular_component C
ND
SceS000001002
GO:0005737 cytoplasm C
IDA
HsaBRAP
ISO
MmuMGI:1919649
GO:0005829 cytosol C
IDA
SpoSPAC16E8.13
GO:0003824 catalytic activity F
ISS
AthAt2g26000
GO:0004842 ubiquitin-protein ligase activity F
IDA
HsaBRAP
ISO
MmuMGI:1919649
ISS
SpoSPAC16E8.13
GO:0005515 protein binding F
IPI
HsaBRAP
GO:0008139 nuclear localization sequence binding F
IDA
HsaBRAP
SceS000001002
ISO
MmuMGI:1919649
GO:0008270 zinc ion binding F
ISS
SpoSPAC16E8.13
GO:0042802 identical protein binding F
IPI
HsaBRAP
GO:0043130 ubiquitin binding F
IDA
SceS000001002
GO:0000165 MAPKKK cascade P
IDA
HsaBRAP
ISO
MmuMGI:1919649
GO:0007265 Ras protein signal transduction P
IDA
HsaBRAP
ISO
MmuMGI:1919649
GO:0009968 negative regulation of signal transduction P
IDA
HsaBRAP
GO:0016567 protein ubiquitination P
ISO
MmuMGI:1919649
ISS
SpoSPAC16E8.13
GO:0045471 response to ethanol P
IMP
SceS000001002

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2670

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4251 ENSANGP00000017603
Ashbya gossypii (Ago) ago4232 AGL079C
Arabidopsis thaliana (Ath) ath9524 At2g26000.1
Arabidopsis thaliana (Ath) ath11387 At2g42160.1
Caenorhabditis elegans (Cel) cel5329 EEED8.16
(CE28903;
WBGene00017144)
Candida glabrata (Cgl) cgl3632 CAGL0K02563g
Cryptococcus neoformans (Cne) cne4497 177.m03258
Dictyostelium discoideum (Ddi) ddi2582 DDB0190874
Debaryomyces hansenii (Dha) dha5873 DEHA0G04004g
Drosophila melanogaster (Dme) dme13350 CG5555-PA
(FBgn0038686)
Danio rerio (Dre) dre24710 ENSDARP00000006402
(brap)
Q6DGJ4
Takifugu rubripes (Fru) fru25241 SINFRUP00000145409
Takifugu rubripes (Fru) fru25242 SINFRUP00000167412
Gallus gallus (Gga) gga7265 ENSGALP00000007395
(BRAP)
Q5ZL09
Gallus gallus (Gga) gga7266 ENSGALP00000007396
Homo sapiens (Hsa) hsa8206 ENSP00000330813
(BRAP)
Q7Z569
Kluyveromyces lactis (Kla) kla5226 KLLA0F25740g
Mus musculus (Mmu) mmu20859 ENSMUSP00000031414
(MGI:1919649)
Q99MP8-1
Mus musculus (Mmu) mmu20860 ENSMUSP00000077804
Oryza sativa (Osa) osa82859 8283.m00162
Oryza sativa (Osa) osa82881 8283.m00196
Plasmodium falciparum (Pfa) pfa3663 PFE1070c
Saccharomyces cerevisiae (Sce) sce2696 YHL010C
(S000001002)
Schizosaccharomyces pombe (Spo) spo662 SPAC16E8.13 O13747
Yarrowia lipolytica (Yli) yli2030 YALI0C07700g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
ISO
MmuMGI:1919649
GO:0005575 cellular_component C
ND
SceS000001002
GO:0005737 cytoplasm C
ISO
MmuMGI:1919649
GO:0005829 cytosol C
IDA
SpoSPAC16E8.13
GO:0003824 catalytic activity F
ISS
AthAt2g42160
At2g26000
GO:0004842 ubiquitin-protein ligase activity F
ISO
MmuMGI:1919649
ISS
SpoSPAC16E8.13
GO:0008139 nuclear localization sequence binding F
IDA
SceS000001002
ISO
MmuMGI:1919649
GO:0008270 zinc ion binding F
ISS
SpoSPAC16E8.13
GO:0043130 ubiquitin binding F
IDA
SceS000001002
GO:0000165 MAPKKK cascade P
ISO
MmuMGI:1919649
GO:0007265 Ras protein signal transduction P
ISO
MmuMGI:1919649
GO:0016567 protein ubiquitination P
ISO
MmuMGI:1919649
ISS
SpoSPAC16E8.13
GO:0045471 response to ethanol P
IMP
SceS000001002

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC16E8.13
(O13747)
YHL010C
(S000001002)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000001002
GO:0005829 cytosol C
IDA
SpoSPAC16E8.13
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC16E8.13
GO:0008139 nuclear localization sequence binding F
IDA
SceS000001002
GO:0008270 zinc ion binding F
ISS
SpoSPAC16E8.13
GO:0043130 ubiquitin binding F
IDA
SceS000001002
GO:0016567 protein ubiquitination P
ISS
SpoSPAC16E8.13
GO:0045471 response to ethanol P
IMP
SceS000001002

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GO info in one table:

s.khadayate@ucl.ac.uk