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Search term: YHL022C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPO11
SGD link S000001014
Alternative ID YHL022C
Description Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation
Synonyms YHL022C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2795 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Catalytic subunit of the meiotic double strand break transesterase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63990 GI:15222586
Arabidopsis thaliana (Ath) At3g13170 GI:15231162
Arabidopsis thaliana (Ath) At5g02820 GI:15241959
Caenorhabditis elegans (Cel) CE06363
(WBGene00004985)
GI:17542064 Q22236
Drosophila melanogaster (Dme) 7302468 GI:17136330
Homo sapiens (Hsa) Hs6912680
(SPO11)
GI:6912680 Q9Y5K1
Saccharomyces cerevisiae (Sce) YHL022c
(S000001014)
GI:6321765 P23179
Schizosaccharomyces pombe (Spo) SPAC17A5.11 GI:19114391 P40384
Encephalitozoon cuniculi (Ecu) ECU04g1110 GI:19074189 Q8SVS9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000001014
ISS
SpoSPAC17A5.11
GO:0005634 nucleus C
IDA
AthAt3g13170
At5g02820
SpoSPAC17A5.11
GO:0005829 cytosol C
IDA
SpoSPAC17A5.11
GO:0003677 DNA binding F
IDA
AthAt3g13170
ISS
AthAt3g13170
At1g63990
At5g02820
SpoSPAC17A5.11
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity
F
ISS
AthAt5g02820
At1g63990
At3g13170
TAS
AthAt5g02820
GO:0005515 protein binding F
IPI
AthAt5g02820
GO:0005524 ATP binding F
ISS
AthAt5g02820
At3g13170
At1g63990
SpoSPAC17A5.11
GO:0016889 endodeoxyribonuclease activity, producing
3'-phosphomonoesters
F
IMP
SceS000001014
ISS
SpoSPAC17A5.11
GO:0042802 identical protein binding F
IPI
AthAt5g02820
GO:0000003 reproduction P
IMP
CelWBGene00004985
GO:0000706 meiotic DNA double-strand break
processing
P
IGI
AthAt3g13170
GO:0002119 nematode larval development P
IMP
CelWBGene00004985
GO:0006259 DNA metabolic process P
ISS
AthAt3g13170
At5g02820
At1g63990
GO:0006265 DNA topological change P
ISS
AthAt3g13170
At1g63990
At5g02820
GO:0006308 DNA catabolic process P
RCA
SceS000001014
GO:0007126 meiosis P
IMP
AthAt1g63990
CelWBGene00004985
GO:0007129 synapsis P
IMP
AthAt3g13170
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt3g13170
SpoSPAC17A5.11
GO:0007283 spermatogenesis P
TAS
HsaSPO11
GO:0007292 female gamete generation P
TAS
HsaSPO11
GO:0009553 embryo sac development P
IMP
AthAt1g63990
GO:0009555 pollen development P
IMP
AthAt1g63990
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004985
GO:0009957 epidermal cell fate specification P
IMP
AthAt5g02820
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000001014
GO:0034090 maintenance of meiotic sister chromatid
cohesion
P
IGI
AthAt3g13170
GO:0040007 growth P
IMP
CelWBGene00004985
GO:0042138 meiotic DNA double-strand break
formation
P
IGI
AthAt3g13170
At1g63990
SceS000001014
IMP
SceS000001014
SpoSPAC17A5.11
GO:0045143 homologous chromosome segregation P
IMP
SpoSPAC17A5.11
GO:0045144 meiotic sister chromatid segregation P
IMP
SpoSPAC17A5.11
GO:0048316 seed development P
IMP
AthAt1g63990
GO:0051026 chiasma assembly P
IMP
AthAt3g13170
At1g63990
GO:0051321 meiotic cell cycle P
RCA
SceS000001014

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48755

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SPO11
(S000001014)
GI:6321765 P23179
Kluyveromyces lactis (Kla) KLLA0D14575g GI:50307459
Eremothecium gossypii (Ego) AGOS_ADR025W GI:45187898


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000001014
GO:0016889 endodeoxyribonuclease activity, producing
3'-phosphomonoesters
F
IMP
SceS000001014
GO:0006308 DNA catabolic process P
RCA
SceS000001014
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000001014
GO:0042138 meiotic DNA double-strand break
formation
P
IGI
SceS000001014
IMP
SceS000001014
GO:0051321 meiotic cell cycle P
RCA
SceS000001014

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1270

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga7913 ENSANGP00000012461
Ashbya gossypii (Ago) ago1766 ADR025W
Arabidopsis thaliana (Ath) ath13472 At3g13170.1
Arabidopsis thaliana (Ath) ath22433 At5g02820.1
Caenorhabditis elegans (Cel) cel14640 T05E11.4
(CE06363;
WBGene00004985)
Candida glabrata (Cgl) cgl538 CAGL0C02783g
Debaryomyces hansenii (Dha) dha1250 DEHA0B13156g
Drosophila melanogaster (Dme) dme6066 CG7753-PA
(FBgn0002716)
Danio rerio (Dre) dre14928 ENSDARP00000002837
(zgc:77876)
Q6P0S6
Danio rerio (Dre) dre23845 ENSDARP00000038973
Danio rerio (Dre) dre14924 ENSDARP00000041506
Encephalitozoon cuniculi (Ecu) ecu827 19074189
Takifugu rubripes (Fru) fru5857 SINFRUP00000135024
Gallus gallus (Gga) gga12203 ENSGALP00000012397
(SPO11)
Homo sapiens (Hsa) hsa20475 ENSP00000216910
Homo sapiens (Hsa) hsa20476 ENSP00000316034
(SPO11)
Q9Y5K1-2
Kluyveromyces lactis (Kla) kla2707 KLLA0D14575g
Mus musculus (Mmu) mmu16119 ENSMUSP00000059056
(MGI:1349669)
Q9WTK8-1
Neurospora crassa (Ncr) ncr1084 NCU01120.2
Oryza sativa (Osa) osa63029 6685.m00141
Oryza sativa (Osa) osa70002 6976.m00155
Oryza sativa (Osa) osa85867 8751.m00180
Plasmodium falciparum (Pfa) pfa4950 PFL0825c
Rattus norvegicus (Rno) rno20375 ENSRNOP00000008959
(RGD:1306454)
Saccharomyces cerevisiae (Sce) sce2710 YHL022C
(S000001014)
Schizosaccharomyces pombe (Spo) spo595 SPAC17A5.11 P40384
Yarrowia lipolytica (Yli) yli6030 YALI0F16335g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000001014
ISS
SpoSPAC17A5.11
GO:0005634 nucleus C
IDA
AthAt3g13170
At5g02820
SpoSPAC17A5.11
GO:0005829 cytosol C
IDA
SpoSPAC17A5.11
GO:0003677 DNA binding F
IDA
AthAt3g13170
ISS
AthAt3g13170
At5g02820
SpoSPAC17A5.11
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity
F
ISS
AthAt5g02820
At3g13170
DmeFBgn0002716
NAS
DmeFBgn0002716
TAS
AthAt5g02820
GO:0005515 protein binding F
IPI
AthAt5g02820
GO:0005524 ATP binding F
ISS
AthAt5g02820
At3g13170
SpoSPAC17A5.11
GO:0016889 endodeoxyribonuclease activity, producing
3'-phosphomonoesters
F
IMP
SceS000001014
ISS
SpoSPAC17A5.11
GO:0042802 identical protein binding F
IPI
AthAt5g02820
GO:0000003 reproduction P
IMP
CelWBGene00004985
GO:0000238 zygotene P
IMP
MmuMGI:1349669
GO:0000706 meiotic DNA double-strand break
processing
P
IGI
AthAt3g13170
GO:0001541 ovarian follicle development P
IMP
MmuMGI:1349669
GO:0002119 nematode larval development P
IMP
CelWBGene00004985
GO:0006259 DNA metabolic process P
ISS
AthAt3g13170
At5g02820
GO:0006265 DNA topological change P
ISS
AthAt3g13170
At5g02820
GO:0006308 DNA catabolic process P
RCA
SceS000001014
GO:0007126 meiosis P
IMP
CelWBGene00004985
GO:0007129 synapsis P
IMP
AthAt3g13170
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt3g13170
DmeFBgn0002716
MmuMGI:1349669
SpoSPAC17A5.11
TAS
DmeFBgn0002716
GO:0007141 male meiosis I P
IMP
MmuMGI:1349669
GO:0007286 spermatid development P
IMP
MmuMGI:1349669
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004985
GO:0009957 epidermal cell fate specification P
IMP
AthAt5g02820
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000001014
GO:0034090 maintenance of meiotic sister chromatid
cohesion
P
IGI
AthAt3g13170
GO:0040007 growth P
IMP
CelWBGene00004985
GO:0042138 meiotic DNA double-strand break
formation
P
IGI
AthAt3g13170
SceS000001014
IMP
SceS000001014
SpoSPAC17A5.11
NAS
DmeFBgn0002716
GO:0042139 early meiotic recombination nodule
assembly
P
IMP
DmeFBgn0002716
GO:0042140 late meiotic recombination nodule
assembly
P
IMP
DmeFBgn0002716
GO:0045143 homologous chromosome segregation P
IMP
SpoSPAC17A5.11
GO:0045144 meiotic sister chromatid segregation P
IMP
SpoSPAC17A5.11
GO:0051026 chiasma assembly P
IMP
AthAt3g13170
GO:0051321 meiotic cell cycle P
RCA
SceS000001014

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC17A5.11
(P40384)
YHL022C
(S000001014)