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Search term: YHR004C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NEM1
SGD link S000001046
Alternative ID YHR004C
Description Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard
Synonyms YHR004C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1605 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING TFIIF-interacting CTD phosphatase, including NLI-interacting factor (involved in RNA polymerase II regulation)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g29770 GI:15220551
Arabidopsis thaliana (Ath) At1g29780 GI:15220552
Arabidopsis thaliana (Ath) At3g55960 GI:15228783
Arabidopsis thaliana (Ath) At4g18140 GI:15236765
Arabidopsis thaliana (Ath) At5g11860 GI:15239800
Arabidopsis thaliana (Ath) At5g45700 GI:15242476
Arabidopsis thaliana (Ath) At5g46410 GI:15237434
Caenorhabditis elegans (Cel) CE02737
(WBGene00018474)		 GI:17534111 Q20432
Caenorhabditis elegans (Cel) CE07727 GI:17505340
Caenorhabditis elegans (Cel) CE22072
(WBGene00021629)		 GI:17509983 Q9N4V4
Drosophila melanogaster (Dme) 7292341 GI:7292341
Drosophila melanogaster (Dme) 7294201 GI:7294201
Drosophila melanogaster (Dme) 7295520
(FBgn0029067)		 GI:20129109
Drosophila melanogaster (Dme) 7300952_2 GI:4972728
Drosophila melanogaster (Dme) 7304015 GI:7304015
Homo sapiens (Hsa) Hs10864009
(CTDSP1)		 GI:10864009 Q9HBT0
Homo sapiens (Hsa) Hs17461521 GI:17461521
Homo sapiens (Hsa) Hs19923330 GI:19923330
Homo sapiens (Hsa) Hs20560426_2 GI:20560426
Homo sapiens (Hsa) Hs21450802_2 GI:16553992 Q8WVY7
Homo sapiens (Hsa) Hs22055643 GI:22055643
Homo sapiens (Hsa) Hs22060597_2 GI:22060597
Homo sapiens (Hsa) Hs22064567 GI:14424544 O95476
Homo sapiens (Hsa) Hs5031775 GI:5031775
Homo sapiens (Hsa) Hs7661722 GI:7661722
Homo sapiens (Hsa) Hs7705461 GI:7705461
Saccharomyces cerevisiae (Sce) YHR004c
(S000001046)		 GI:6321791 P38757
Saccharomyces cerevisiae (Sce) YLL010c
(S000003933)		 GI:6323019 Q07800
Saccharomyces cerevisiae (Sce) YLR019w
(S000004009)		 GI:6323047 Q07949
Schizosaccharomyces pombe (Spo) SPAC2F7.02c GI:19113885 Q09695
Schizosaccharomyces pombe (Spo) SPBC1271.03c GI:19111939 O94336
Schizosaccharomyces pombe (Spo) SPBC3B8.10c GI:19113196 O59718
Encephalitozoon cuniculi (Ecu) ECU10g1270 GI:19074736 Q8SUC7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
IDA
AthAt5g11860
GO:0005634 nucleus C
IDA
AthAt5g11860
At5g46410
At4g18140
HsaCTDSP1
SpoSPBC1271.03c
TAS
HsaCTDSP1
GO:0005694 chromosome C
IDA
AthAt5g11860
GO:0005730 nucleolus C
IDA
SpoSPBC1271.03c
GO:0005737 cytoplasm C
IDA
AthAt5g11860
GO:0005739 mitochondrion C
IDA
SceS000001046
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC3B8.10c
GO:0005829 cytosol C
IDA
SpoSPBC1271.03c
GO:0005886 plasma membrane C
IDA
SceS000003933
ISS
SceS000004009
SpoSPAC2F7.02c
SPBC1271.03c
GO:0008287 protein serine/threonine phosphatase
complex		 C
NAS
SpoSPBC3B8.10c
GO:0016021 integral to membrane C
IDA
SceS000001046
ISM
SceS000001046
NAS
SpoSPBC3B8.10c
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0004721 phosphoprotein phosphatase activity F
IDA
SceS000001046
S000003933
ISS
SceS000003933
S000004009
SpoSPAC2F7.02c
SPBC3B8.10c
SPBC1271.03c
GO:0005515 protein binding F
IPI
HsaCTDSP1
GO:0008420 CTD phosphatase activity F
IDA
AthAt5g46410
At5g11860
At4g18140
HsaCTDSP1
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IDA
HsaCTDSP1
GO:0006414 translational elongation P
RCA
SceS000003933
GO:0006470 protein amino acid dephosphorylation P
IC
SpoSPAC2F7.02c
IDA
AthAt4g18140
At5g11860
At5g46410
HsaCTDSP1
ISS
SpoSPBC3B8.10c
SPBC1271.03c
GO:0006950 response to stress P
IGI
SceS000003933
S000004009
GO:0006998 nuclear envelope organization P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0007165 signal transduction P
NAS
SpoSPAC2F7.02c
SPBC1271.03c
GO:0008150 biological_process P
ND
AthAt3g55960
At1g29770
GO:0030437 ascospore formation P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0033554 cellular response to stress P
IEP
SpoSPBC3B8.10c
ISS
SpoSPAC2F7.02c
SPBC1271.03c
GO:0046890 regulation of lipid biosynthetic
process		 P
IGI
SceS000001046
ISS
SpoSPBC3B8.10c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117820

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) NEM1
(S000001046)		 GI:6321791 P38757
Kluyveromyces lactis (Kla) KLLA0E18700g GI:50309561
Eremothecium gossypii (Ego) AGOS_AGL070W GI:45201026


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001046
GO:0016021 integral to membrane C
IDA
SceS000001046
ISM
SceS000001046
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000001046
GO:0004721 phosphoprotein phosphatase activity F
IDA
SceS000001046
GO:0006998 nuclear envelope organization P
IMP
SceS000001046
GO:0030437 ascospore formation P
IMP
SceS000001046
GO:0046890 regulation of lipid biosynthetic
process		 P
IGI
SceS000001046

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4206

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1703 ENSANGP00000020581
Ashbya gossypii (Ago) ago4241 AGL070W
Caenorhabditis elegans (Cel) cel9232 F45E12.1
(CE02737;
WBGene00018474)
Candida glabrata (Cgl) cgl3648 CAGL0K02959g
Cryptococcus neoformans (Cne) cne877 163.m06247
Dictyostelium discoideum (Ddi) ddi9296 DDB0186834
Dictyostelium discoideum (Ddi) ddi9297 DDB0186835
Debaryomyces hansenii (Dha) dha814 DEHA0B03003g
Drosophila melanogaster (Dme) dme7753 CG12078-PA
(FBgn0035426)
Drosophila melanogaster (Dme) dme18882 CG1696-PA
(FBgn0029067)
Drosophila melanogaster (Dme) dme3917 CG8584-PA
(FBgn0033322)
Danio rerio (Dre) dre18884 ENSDARP00000021202
(dullardl)		 Q5U3T3
Takifugu rubripes (Fru) fru8540 SINFRUP00000158896
Homo sapiens (Hsa) hsa12947 ENSP00000321732
(DULLARD)		 O95476
Kluyveromyces lactis (Kla) kla3791 KLLA0E18700g
Mus musculus (Mmu) mmu4058 ENSMUSP00000018703
(MGI:1914431)		 Q3TP92
Neurospora crassa (Ncr) ncr8721 NCU08948.2
Rattus norvegicus (Rno) rno5382 ENSRNOP00000023379
(RGD:1310172)		 Q3B7T6
Saccharomyces cerevisiae (Sce) sce2748 YHR004C
(S000001046)
Schizosaccharomyces pombe (Spo) spo2003 SPBC3B8.10c O59718
Yarrowia lipolytica (Yli) yli1834 YALI0C02849g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914431
GO:0005739 mitochondrion C
IDA
SceS000001046
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC3B8.10c
GO:0008287 protein serine/threonine phosphatase
complex		 C
NAS
SpoSPBC3B8.10c
GO:0016021 integral to membrane C
IDA
SceS000001046
ISM
SceS000001046
NAS
SpoSPBC3B8.10c
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0003674 molecular_function F
ND
MmuMGI:1914431
GO:0004721 phosphoprotein phosphatase activity F
IDA
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0006470 protein amino acid dephosphorylation P
ISS
SpoSPBC3B8.10c
GO:0006998 nuclear envelope organization P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0008150 biological_process P
ND
MmuMGI:1914431
GO:0030437 ascospore formation P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0033554 cellular response to stress P
IEP
SpoSPBC3B8.10c
GO:0046890 regulation of lipid biosynthetic
process		 P
IGI
SceS000001046
ISS
SpoSPBC3B8.10c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3B8.10c
(O59718)		 YHR004C
(S000001046)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001046
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC3B8.10c
GO:0008287 protein serine/threonine phosphatase
complex		 C
NAS
SpoSPBC3B8.10c
GO:0016021 integral to membrane C
IDA
SceS000001046
ISM
SceS000001046
NAS
SpoSPBC3B8.10c
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0004721 phosphoprotein phosphatase activity F
IDA
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0006470 protein amino acid dephosphorylation P
ISS
SpoSPBC3B8.10c
GO:0006998 nuclear envelope organization P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0030437 ascospore formation P
IMP
SceS000001046
ISS
SpoSPBC3B8.10c
GO:0033554 cellular response to stress P
IEP
SpoSPBC3B8.10c
GO:0046890 regulation of lipid biosynthetic
process		 P
IGI
SceS000001046
ISS
SpoSPBC3B8.10c

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GO info in one table:

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