YOGY Home YOGY Help

Search term: YHR037W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PUT2
SGD link S000001079
Alternative ID YHR037W
Description Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism
Synonyms YHR037W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2455 -CDHYP-

KOGs classification KOGs description
METABOLISM Delta-1-pyrroline-5-carboxylate dehydrogenase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE29047
(WBGene00000112)
GI:17534447 O16648
Drosophila melanogaster (Dme) 7294423 GI:7294423
Drosophila melanogaster (Dme) 7296504 GI:7296504
Drosophila melanogaster (Dme) 7300788 GI:7300788
Homo sapiens (Hsa) Hs4502037 GI:4502037
Saccharomyces cerevisiae (Sce) YHR037w
(S000001079)
GI:6321826 P07275
Schizosaccharomyces pombe (Spo) SPBC24C6.04 GI:19112750 O74766


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0005759 mitochondrial matrix C
IDA
SceS000001079
GO:0005829 cytosol C
IDA
SpoSPBC24C6.04
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase
activity
F
IDA
SceS000001079
IMP
SceS000001079
ISS
SpoSPBC24C6.04
GO:0016903 oxidoreductase activity, acting on the aldehyde or
oxo group of donors
F
RCA
SceS000001079
GO:0000003 reproduction P
IMP
CelWBGene00000112
GO:0006537 glutamate biosynthetic process P
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0006561 proline biosynthetic process P
ISS
SpoSPBC24C6.04
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000112
GO:0010133 proline catabolic process to glutamate P
IMP
SceS000001079
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000112
GO:0040011 locomotion P
IMP
CelWBGene00000112
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00000112
GO:0055114 oxidation reduction P
RCA
SceS000001079

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6081

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ALDH4A1 GI:25777736
Canis familiaris (Cfa) ALDH4A1 GI:73950694
Mus musculus (Mmu) Aldh4a1
(MGI:2443883)
GI:34328415 Q6P9Q7
Rattus norvegicus (Rno) Tas1r2
(RGD:61894)
GI:109475727
Gallus gallus (Gga) ALDH4A1 GI:118101121
Drosophila melanogaster (Dme) CG7145
(FBgn0037138)
GI:24668417
Anopheles gambiae (Aga) AgaP_AGAP004366 GI:158292087
Caenorhabditis elegans (Cel) alh-6
(CE29047;
WBGene00000112)
GI:17534447 O16648
Schizosaccharomyces pombe (Spo) SPBC24C6.04 GI:19112750 O74766
Saccharomyces cerevisiae (Sce) PUT2
(S000001079)
GI:6321826 P07275
Kluyveromyces lactis (Kla) KLLA0C10549g GI:50305421
Eremothecium gossypii (Ego) AGOS_AAL071C GI:45184753
Magnaporthe grisea (Mgr) MGG_00189 GI:39975329
Neurospora crassa (Ncr) NCU03076.1 GI:32420137


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:2443883
SceS000001079
ISS
SpoSPBC24C6.04
GO:0005759 mitochondrial matrix C
IDA
SceS000001079
ISS
DmeFBgn0037138
GO:0005829 cytosol C
IDA
SpoSPBC24C6.04
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase
activity
F
IDA
SceS000001079
IMP
SceS000001079
ISS
DmeFBgn0037138
SpoSPBC24C6.04
GO:0004029 aldehyde dehydrogenase (NAD) activity F
TAS
HsaALDH4A1
GO:0009055 electron carrier activity F
TAS
HsaALDH4A1
GO:0016903 oxidoreductase activity, acting on the aldehyde or
oxo group of donors
F
RCA
SceS000001079
GO:0000003 reproduction P
IMP
CelWBGene00000112
GO:0006537 glutamate biosynthetic process P
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0006560 proline metabolic process P
ISS
DmeFBgn0037138
TAS
HsaALDH4A1
GO:0006561 proline biosynthetic process P
ISS
SpoSPBC24C6.04
GO:0006562 proline catabolic process P
TAS
HsaALDH4A1
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000112
GO:0010133 proline catabolic process to glutamate P
IMP
SceS000001079
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000112
GO:0040011 locomotion P
IMP
CelWBGene00000112
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00000112
GO:0055114 oxidation reduction P
RCA
SceS000001079

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2757

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6910 ENSANGP00000013138
Ashbya gossypii (Ago) ago116 AAL071C
Caenorhabditis elegans (Cel) cel10586 F56D12.1a
(CE29047;
WBGene00000112)
Candida glabrata (Cgl) cgl834 CAGL0D03982g
Dictyostelium discoideum (Ddi) ddi12322 DDB0229934
Debaryomyces hansenii (Dha) dha6672 DEHA0G21769g
Drosophila melanogaster (Dme) dme10674 CG7145-PA
(FBgn0037138)
Drosophila melanogaster (Dme) dme10676 CG7145-PB
(FBgn0037138)
Drosophila melanogaster (Dme) dme10675 CG7145-PD
(FBgn0037138)
Escherichia coli (Eco) eco983 16128980
Gallus gallus (Gga) gga12551 ENSGALP00000006026
Homo sapiens (Hsa) hsa432 ENSP00000290597
(ALDH4A1)
P30038
Homo sapiens (Hsa) hsa431 ENSP00000336944
Kluyveromyces lactis (Kla) kla1669 KLLA0C10549g
Mus musculus (Mmu) mmu19219 ENSMUSP00000043821
(MGI:2443883)
B1AXW8
Mus musculus (Mmu) mmu19220 ENSMUSP00000077439
Neurospora crassa (Ncr) ncr2980 NCU03076.2
Rattus norvegicus (Rno) rno24245 ENSRNOP00000025090
(RGD:1624206)
P0C2X9
Saccharomyces cerevisiae (Sce) sce2788 YHR037W
(S000001079)
Schizosaccharomyces pombe (Spo) spo4547 SPBC24C6.04 O74766
Yarrowia lipolytica (Yli) yli1134 YALI0B09647g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:2443883
SceS000001079
ISS
SpoSPBC24C6.04
GO:0005759 mitochondrial matrix C
IDA
SceS000001079
ISS
DmeFBgn0037138
GO:0005829 cytosol C
IDA
SpoSPBC24C6.04
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase
activity
F
IDA
SceS000001079
IMP
SceS000001079
ISS
DmeFBgn0037138
SpoSPBC24C6.04
GO:0016903 oxidoreductase activity, acting on the aldehyde or
oxo group of donors
F
RCA
SceS000001079
GO:0000003 reproduction P
IMP
CelWBGene00000112
GO:0006537 glutamate biosynthetic process P
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0006560 proline metabolic process P
ISS
DmeFBgn0037138
GO:0006561 proline biosynthetic process P
ISS
SpoSPBC24C6.04
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000112
GO:0010133 proline catabolic process to glutamate P
IMP
SceS000001079
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000112
GO:0040011 locomotion P
IMP
CelWBGene00000112
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00000112
GO:0055114 oxidation reduction P
RCA
SceS000001079

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC24C6.04
(O74766)
YHR037W
(S000001079)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0005759 mitochondrial matrix C
IDA
SceS000001079
GO:0005829 cytosol C
IDA
SpoSPBC24C6.04
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase
activity
F
IDA
SceS000001079
IMP
SceS000001079
ISS
SpoSPBC24C6.04
GO:0016903 oxidoreductase activity, acting on the aldehyde or
oxo group of donors
F
RCA
SceS000001079
GO:0006537 glutamate biosynthetic process P
IDA
SceS000001079
ISS
SpoSPBC24C6.04
GO:0006561 proline biosynthetic process P
ISS
SpoSPBC24C6.04
GO:0010133 proline catabolic process to glutamate P
IMP
SceS000001079
GO:0055114 oxidation reduction P
RCA
SceS000001079

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk