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Search term: YHR041C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SRB2
SGD link S000001083
Alternative ID YHR041C
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance
Synonyms YHR041C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39218

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SRB2
(S000001083)
GI:6321831
Kluyveromyces lactis (Kla) KLLA0C10780g GI:50305441
Eremothecium gossypii (Ego) AGOS_AAL082W GI:45184742


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016592 mediator complex C
IDA
SceS000001083
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000001083
GO:0000398 nuclear mRNA splicing, via spliceosome P
RCA
SceS000001083
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000001083
RCA
SceS000001083
GO:0006397 mRNA processing P
RCA
SceS000001083
GO:0008380 RNA splicing P
RCA
SceS000001083
GO:0010689 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to chemical stimulus
P
IMP
SceS000001083
GO:0010691 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to nutrient levels
P
IMP
SceS000001083
GO:0016071 mRNA metabolic process P
RCA
SceS000001083

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20806

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago105 AAL082W
Candida glabrata (Cgl) cgl841 CAGL0D04136g
Debaryomyces hansenii (Dha) dha828 DEHA0B03278g
Kluyveromyces lactis (Kla) kla1679 KLLA0C10780g
Saccharomyces cerevisiae (Sce) sce2793 YHR041C
(S000001083)
Yarrowia lipolytica (Yli) yli2656 YALI0C23320g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016592 mediator complex C
IDA
SceS000001083
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000001083
GO:0000398 nuclear mRNA splicing, via spliceosome P
RCA
SceS000001083
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000001083
RCA
SceS000001083
GO:0006397 mRNA processing P
RCA
SceS000001083
GO:0008380 RNA splicing P
RCA
SceS000001083
GO:0010689 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to chemical stimulus
P
IMP
SceS000001083
GO:0010691 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to nutrient levels
P
IMP
SceS000001083
GO:0016071 mRNA metabolic process P
RCA
SceS000001083

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC17G8.05
(Q10317)
YHR041C
(S000001083)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17G8.05
ISS
SpoSPAC17G8.05
GO:0016592 mediator complex C
IDA
SceS000001083
SpoSPAC17G8.05
GO:0005515 protein binding F
IPI
SpoSPAC17G8.05
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000001083
ISS
SpoSPAC17G8.05
GO:0000398 nuclear mRNA splicing, via spliceosome P
RCA
SceS000001083
GO:0006366 transcription from RNA polymerase II
promoter
P
IC
SpoSPAC17G8.05
IDA
SceS000001083
RCA
SceS000001083
GO:0006397 mRNA processing P
RCA
SceS000001083
GO:0008380 RNA splicing P
RCA
SceS000001083
GO:0010689 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to chemical stimulus
P
IMP
SceS000001083
GO:0010691 negative regulation of ribosomal protein gene
transcription from RNA polymerase II promoter in
response to nutrient levels
P
IMP
SceS000001083
GO:0016071 mRNA metabolic process P
RCA
SceS000001083
GO:0034613 cellular protein localization P
IGI
SpoSPAC17G8.05

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