Search term: YHR050W

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1291	ACDHYP-

KOGs classification	KOGs description
METABOLISM	Mn2+ and Fe2+ transporters of the NRAMP family

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g15960	GI:15218378
Arabidopsis thaliana (Ath)	At1g47240	GI:15220149
Arabidopsis thaliana (Ath)	At1g80830	GI:15220858
Arabidopsis thaliana (Ath)	At2g23150	GI:15227785
Arabidopsis thaliana (Ath)	At4g18790	GI:15234018
Arabidopsis thaliana (Ath)	At5g03280	GI:15242709
Arabidopsis thaliana (Ath)	At5g67330	GI:15240711
Caenorhabditis elegans (Cel)	CE02825 (WBGene00004877)	GI:17569473	Q21433
Caenorhabditis elegans (Cel)	CE02826	GI:17569471
Caenorhabditis elegans (Cel)	CE26561	GI:17543998
Drosophila melanogaster (Dme)	7300692	GI:17738083
Homo sapiens (Hsa)	Hs14733520	GI:14733520
Homo sapiens (Hsa)	Hs10835151	GI:10835151
Homo sapiens (Hsa)	Hs10835169 (SLC11A2)	GI:10835169	P49281
Saccharomyces cerevisiae (Sce)	YHR050w (S000001092)	GI:6321841	P38778
Saccharomyces cerevisiae (Sce)	YLR034c (S000004024)	GI:6323062	Q12078
Saccharomyces cerevisiae (Sce)	YOL122c (S000005482)	GI:6324450	P38925
Schizosaccharomyces pombe (Spo)	SPAC27F1.08	GI:19115449	Q10177

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000329	fungal-type vacuole membrane	C	IDA Sce S000004024
GO:0005634	nucleus	C	IDA Hsa SLC11A2
GO:0005737	cytoplasm	C	IDA Hsa SLC11A2
GO:0005739	mitochondrion	C	IDA Sce S000001092
GO:0005764	lysosome	C	IDA Hsa SLC11A2
GO:0005765	lysosomal membrane	C	IDA Hsa SLC11A2
GO:0005769	early endosome	C	IDA Hsa SLC11A2
GO:0005770	late endosome	C	IDA Hsa SLC11A2
GO:0005773	vacuole	C	IDA Ath At5g67330 At2g23150 IMP Hsa SLC11A2
GO:0005774	vacuolar membrane	C	IDA Ath At5g67330 At2g23150
GO:0005783	endoplasmic reticulum	C	IDA Spo SPAC27F1.08
GO:0005802	trans-Golgi network	C	IDA Hsa SLC11A2
GO:0005886	plasma membrane	C	EXP Hsa SLC11A2 IDA Ath At1g80830 At2g23150 Hsa SLC11A2 Sce S000005482 IMP Hsa SLC11A2
GO:0009986	cell surface	C	IDA Hsa SLC11A2
GO:0016023	cytoplasmic membrane-bounded vesicle	C	IDA Sce S000001092
GO:0016324	apical plasma membrane	C	IDA Hsa SLC11A2
GO:0030176	integral to endoplasmic reticulum membrane	C	IC Spo SPAC27F1.08
GO:0031410	cytoplasmic vesicle	C	IDA Hsa SLC11A2
GO:0031902	late endosome membrane	C	IDA Hsa SLC11A2
GO:0045177	apical part of cell	C	IDA Hsa SLC11A2
GO:0045178	basal part of cell	C	IDA Hsa SLC11A2
GO:0048471	perinuclear region of cytoplasm	C	IDA Hsa SLC11A2
GO:0055037	recycling endosome	C	IDA Hsa SLC11A2
GO:0070826	paraferritin complex	C	IDA Hsa SLC11A2
GO:0005375	copper ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0005381	iron ion transmembrane transporter activity	F	EXP Hsa SLC11A2 IGI Ath At1g80830
GO:0005384	manganese ion transmembrane transporter activity	F	IDA Hsa SLC11A2 IMP Ath At1g80830 TAS Ath At1g80830 At5g67330 At2g23150 Spo SPAC27F1.08
GO:0005515	protein binding	F	IPI Hsa SLC11A2
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	F	IDA Sce S000005482 S000001092 IGI Hsa SLC11A2
GO:0015086	cadmium ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015087	cobalt ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015093	ferrous iron transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015094	lead ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015099	nickel ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015100	vanadium ion transmembrane transporter activity	F	IDA Hsa SLC11A2
GO:0015103	inorganic anion transmembrane transporter activity	F	ISS Ath At1g80830 At5g67330 At1g47240 At1g15960 At4g18790 At2g23150
GO:0015295	solute:hydrogen symporter activity	F	IDA Hsa SLC11A2 Sce S000005482
GO:0046873	metal ion transmembrane transporter activity	F	ISS Ath At4g18790 At1g47240 At1g15960 Sce S000004024 NAS Ath At1g15960 At1g47240 At4g18790 TAS Ath At5g67330 At1g80830 At2g23150
GO:0001666	response to hypoxia	P	IEP Hsa SLC11A2
GO:0001736	establishment of planar polarity	P	IGI Ath At5g03280
GO:0002237	response to molecule of bacterial origin	P	IMP Ath At5g03280
GO:0006824	cobalt ion transport	P	IDA Hsa SLC11A2 IGI Sce S000001092
GO:0006825	copper ion transport	P	IDA Hsa SLC11A2 IGI Sce S000005482
GO:0006826	iron ion transport	P	IGI Sce S000005482 IMP Sce S000004024
GO:0006828	manganese ion transport	P	IDA Hsa SLC11A2 IMP Ath At5g67330 At2g23150 Sce S000001092 S000005482 TAS Ath At1g80830 At2g23150 At5g67330
GO:0006875	cellular metal ion homeostasis	P	NAS Ath At1g80830 At1g47240 At4g18790 At5g67330 At2g23150 At1g15960
GO:0006876	cellular cadmium ion homeostasis	P	IGI Sce S000005482
GO:0006877	cellular cobalt ion homeostasis	P	IGI Sce S000001092
GO:0006878	cellular copper ion homeostasis	P	IGI Sce S000005482
GO:0006879	cellular iron ion homeostasis	P	IGI Ath At5g67330 IMP Sce S000004024
GO:0006919	activation of caspase activity	P	IDA Hsa SLC11A2
GO:0006970	response to osmotic stress	P	IMP Ath At5g03280
GO:0006979	response to oxidative stress	P	TAS Ath At5g03280
GO:0008219	cell death	P	NAS Ath At5g03280
GO:0009408	response to heat	P	IMP Ath At5g03280
GO:0009617	response to bacterium	P	IEP Ath At2g23150
GO:0009624	response to nematode	P	IEP Ath At5g67330
GO:0009651	response to salt stress	P	IMP Ath At5g03280
GO:0009723	response to ethylene stimulus	P	IMP Ath At5g03280
GO:0009725	response to hormone stimulus	P	IMP Ath At5g03280
GO:0009753	response to jasmonic acid stimulus	P	IMP Ath At5g03280
GO:0009789	positive regulation of abscisic acid mediated signaling pathway	P	IMP Ath At5g03280
GO:0009871	jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway	P	TAS Ath At5g03280
GO:0009873	ethylene mediated signaling pathway	P	TAS Ath At5g03280
GO:0009926	auxin polar transport	P	IMP Ath At5g03280
GO:0010039	response to iron ion	P	IEP Ath At5g67330 Hsa SLC11A2
GO:0010043	response to zinc ion	P	IEP Ath At2g23150
GO:0010119	regulation of stomatal movement	P	IMP Ath At5g03280
GO:0010150	leaf senescence	P	IMP Ath At5g03280
GO:0010182	sugar mediated signaling pathway	P	TAS Ath At5g03280
GO:0010670	positive regulation of oxygen and reactive oxygen species metabolic process	P	IGI Ath At2g23150 At5g67330
GO:0015674	di-, tri-valent inorganic cation transport	P	TAS Spo SPAC27F1.08
GO:0015675	nickel ion transport	P	IDA Hsa SLC11A2
GO:0015676	vanadium ion transport	P	IDA Hsa SLC11A2
GO:0015684	ferrous iron transport	P	IDA Hsa SLC11A2
GO:0015691	cadmium ion transport	P	IGI Sce S000005482 TAS Ath At1g80830 At5g67330 At2g23150
GO:0015692	lead ion transport	P	IDA Hsa SLC11A2 TAS Ath At1g80830 At5g67330 At2g23150
GO:0019725	cellular homeostasis	P	IMP Cel WBGene00004877
GO:0030001	metal ion transport	P	ISS Ath At1g15960 At1g47240 At4g18790 NAS Ath At1g47240 At4g18790 At1g15960 TAS Ath At1g80830 At5g67330 At2g23150
GO:0030026	cellular manganese ion homeostasis	P	IGI Spo SPAC27F1.08 IMP Sce S000005482 S000001092
GO:0031348	negative regulation of defense response	P	IMP Ath At5g03280
GO:0034599	cellular response to oxidative stress	P	IDA Hsa SLC11A2
GO:0034755	iron ion transmembrane transport	P	IGI Ath At1g80830
GO:0042742	defense response to bacterium	P	IMP Ath At2g23150 At5g67330 At5g03280
GO:0048765	root hair cell differentiation	P	IGI Ath At5g03280
GO:0050832	defense response to fungus	P	IMP Ath At5g03280
GO:0052544	defense response by callose deposition in cell wall	P	IMP Ath At5g03280
GO:0055071	manganese ion homeostasis	P	IMP Ath At1g80830
GO:0055072	iron ion homeostasis	P	IMP Ath At5g67330 At2g23150
GO:0060586	multicellular organismal iron ion homeostasis	P	IMP Hsa SLC11A2
GO:0070574	cadmium ion transmembrane transport	P	IDA Hsa SLC11A2
GO:0070627	ferrous iron import	P	IDA Hsa SLC11A2
GO:0071421	manganese ion transmembrane transport	P	IMP Spo SPAC27F1.08

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
74696

Species	Gene ID	NCBI link	UniProt link
Saccharomyces cerevisiae (Sce)	SMF2 (S000001092)	GI:6321841	P38778
Kluyveromyces lactis (Kla)	KLLA0D09581g	GI:50307023
Eremothecium gossypii (Ego)	AGOS_ACR037C	GI:45185724

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005739	mitochondrion	C	IDA Sce S000001092
GO:0016023	cytoplasmic membrane-bounded vesicle	C	IDA Sce S000001092
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	F	IDA Sce S000001092
GO:0006824	cobalt ion transport	P	IGI Sce S000001092
GO:0006828	manganese ion transport	P	IMP Sce S000001092
GO:0006877	cellular cobalt ion homeostasis	P	IGI Sce S000001092
GO:0030026	cellular manganese ion homeostasis	P	IMP Sce S000001092

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_301

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga13765	ENSANGP00000000870
Ashbya gossypii (Ago)	ago1085	ACR037C
Ashbya gossypii (Ago)	ago1582	ADL159C
Ashbya gossypii (Ago)	ago3416	AFR224C
Arabidopsis thaliana (Ath)	ath3981	At1g47240.1
Arabidopsis thaliana (Ath)	ath7472	At1g80830.1
Arabidopsis thaliana (Ath)	ath9224	At2g23150.1
Arabidopsis thaliana (Ath)	ath19758	At4g18790.1
Arabidopsis thaliana (Ath)	ath28917	At5g67330.1
Caenorhabditis elegans (Cel)	cel12633	K11G12.3 (CE02825; WBGene00004877)
Caenorhabditis elegans (Cel)	cel12634	K11G12.4a (CE41828; WBGene00004876)
Caenorhabditis elegans (Cel)	cel12635	K11G12.4b (CE37261)
Caenorhabditis elegans (Cel)	cel20437	Y69A2AR.4 (CE36370; WBGene00004878)
Candida glabrata (Cgl)	cgl146	CAGL0A03476g
Candida glabrata (Cgl)	cgl1028	CAGL0E01969g
Candida glabrata (Cgl)	cgl3010	CAGL0J00407g
Dictyostelium discoideum (Ddi)	ddi1727	DDB0202615
Dictyostelium discoideum (Ddi)	ddi3221	DDB0217668
Debaryomyces hansenii (Dha)	dha2606	DEHA0D06996g
Debaryomyces hansenii (Dha)	dha5513	DEHA0F25234g
Debaryomyces hansenii (Dha)	dha6110	DEHA0G09251g
Drosophila melanogaster (Dme)	dme13617	CG3671-PA (FBgn0011672)
Drosophila melanogaster (Dme)	dme13616	CG3671-PB (FBgn0011672)
Drosophila melanogaster (Dme)	dme13618	CG3671-PC (FBgn0011672)
Danio rerio (Dre)	dre14078	ENSDARP00000033139 (slc11a2)	Q8AX90
Escherichia coli (Eco)	eco2319	16130324
Takifugu rubripes (Fru)	fru8954	SINFRUP00000136565
Takifugu rubripes (Fru)	fru29891	SINFRUP00000144221
Gallus gallus (Gga)	gga21761	ENSGALP00000018625 (SLC11A1)	P51027
Homo sapiens (Hsa)	hsa19277	ENSP00000233202 (SLC11A1)	P49279
Homo sapiens (Hsa)	hsa7486	ENSP00000262051 (SLC11A2)	P49281-1
Homo sapiens (Hsa)	hsa7487	ENSP00000262052 (SLC11A2)	P49281-2
Kluyveromyces lactis (Kla)	kla162	KLLA0A03740g
Kluyveromyces lactis (Kla)	kla2488	KLLA0D09581g
Kluyveromyces lactis (Kla)	kla4861	KLLA0F17391g
Mus musculus (Mmu)	mmu9677	ENSMUSP00000023774 (MGI:1345279)	P49282-1
Mus musculus (Mmu)	mmu546	ENSMUSP00000027368 (MGI:1345275)	Q3TB84
Mus musculus (Mmu)	mmu9678	ENSMUSP00000062144
Neurospora crassa (Ncr)	ncr7331	NCU07530.2
Neurospora crassa (Ncr)	ncr8271	NCU08489.2
Oryza sativa (Osa)	osa6826	2485.m00126
Oryza sativa (Osa)	osa30411	4318.m00192
Oryza sativa (Osa)	osa53859	6048.m00080
Oryza sativa (Osa)	osa58412	6260.m00131
Oryza sativa (Osa)	osa66933	6940.m00157
Oryza sativa (Osa)	osa73284	7113.m00131
Oryza sativa (Osa)	osa75342	7195.m00117
Oryza sativa (Osa)	osa79381	7441.m00128
Plasmodium falciparum (Pfa)	pfa3687	PFE1185w
Rattus norvegicus (Rno)	rno30237	ENSRNOP00000020491 (RGD:1601463)
Rattus norvegicus (Rno)	rno27771	ENSRNOP00000026494 (RGD:3684)	O54902-1
Rattus norvegicus (Rno)	rno27772	ENSRNOP00000026531 (RGD:3684)	O54902-2
Saccharomyces cerevisiae (Sce)	sce2803	YHR050W (S000001092)
Saccharomyces cerevisiae (Sce)	sce4114	YLR034C (S000004024)
Saccharomyces cerevisiae (Sce)	sce5680	YOL122C (S000005482)
Schizosaccharomyces pombe (Spo)	spo328	SPAC27F1.08	Q10177
Yarrowia lipolytica (Yli)	yli1899	YALI0C04411g
Yarrowia lipolytica (Yli)	yli3836	YALI0D26818g

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000329	fungal-type vacuole membrane	C	IDA Sce S000004024
GO:0005739	mitochondrion	C	IDA Sce S000001092
GO:0005764	lysosome	C	IDA Mmu MGI:1345275
GO:0005765	lysosomal membrane	C	ISO Mmu MGI:1345279
GO:0005768	endosome	C	IDA Mmu MGI:1345279
GO:0005769	early endosome	C	IDA Mmu MGI:1345279
GO:0005770	late endosome	C	IDA Mmu MGI:1345275 IMP Mmu MGI:1345275
GO:0005773	vacuole	C	IDA Ath At5g67330 At2g23150
GO:0005774	vacuolar membrane	C	IDA Ath At5g67330 At2g23150
GO:0005783	endoplasmic reticulum	C	IDA Spo SPAC27F1.08
GO:0005886	plasma membrane	C	IDA Ath At1g80830 At2g23150 Dme FBgn0011672 Mmu MGI:1345279 Sce S000005482 NAS Dme FBgn0011672
GO:0005887	integral to plasma membrane	C	IDA Mmu MGI:1345279 ISM Dme FBgn0011672 NAS Dme FBgn0011672
GO:0005903	brush border	C	IDA Mmu MGI:1345279
GO:0009279	cell outer membrane	C	IDA Mmu MGI:1345275
GO:0009986	cell surface	C	IDA Mmu MGI:1345279
GO:0010008	endosome membrane	C	IDA Mmu MGI:1345275
GO:0012505	endomembrane system	C	IDA Mmu MGI:1345279
GO:0016020	membrane	C	IDA Dme FBgn0011672
GO:0016021	integral to membrane	C	ISO Mmu MGI:1345279
GO:0016023	cytoplasmic membrane-bounded vesicle	C	IDA Sce S000001092
GO:0030176	integral to endoplasmic reticulum membrane	C	IC Spo SPAC27F1.08
GO:0030670	phagocytic vesicle membrane	C	IDA Mmu MGI:1345275 IMP Mmu MGI:1345275
GO:0031902	late endosome membrane	C	ISO Mmu MGI:1345279
GO:0044444	cytoplasmic part	C	IDA Dme FBgn0011672
GO:0045177	apical part of cell	C	ISO Mmu MGI:1345279
GO:0055037	recycling endosome	C	IDA Mmu MGI:1345279
GO:0005375	copper ion transmembrane transporter activity	F	IMP Dme FBgn0011672 ISO Mmu MGI:1345279
GO:0005381	iron ion transmembrane transporter activity	F	IDA Mmu MGI:1345279 IGI Ath At1g80830 IMP Dme FBgn0011672 ISO Mmu MGI:1345279
GO:0005384	manganese ion transmembrane transporter activity	F	IMP Ath At1g80830 Dme FBgn0011672 Mmu MGI:1345275 ISO Mmu MGI:1345279 TAS Ath At1g80830 At5g67330 At2g23150 Spo SPAC27F1.08
GO:0005506	iron ion binding	F	ISO Mmu MGI:1345279
GO:0005507	copper ion binding	F	ISO Mmu MGI:1345279
GO:0008270	zinc ion binding	F	ISO Mmu MGI:1345279
GO:0015078	hydrogen ion transmembrane transporter activity	F	IDA Mmu MGI:1345279
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	F	IDA Sce S000005482 S000001092
GO:0015086	cadmium ion transmembrane transporter activity	F	ISO Mmu MGI:1345279
GO:0015087	cobalt ion transmembrane transporter activity	F	IDA Mmu MGI:1345279 ISO Mmu MGI:1345279
GO:0015093	ferrous iron transmembrane transporter activity	F	IDA Mmu MGI:1345279 ISO Mmu MGI:1345279
GO:0015094	lead ion transmembrane transporter activity	F	ISO Mmu MGI:1345279
GO:0015099	nickel ion transmembrane transporter activity	F	ISO Mmu MGI:1345279
GO:0015103	inorganic anion transmembrane transporter activity	F	ISS Ath At1g80830 At5g67330 At1g47240 At4g18790 At2g23150
GO:0015293	symporter activity	F	IGI Dme FBgn0011672
GO:0015295	solute:hydrogen symporter activity	F	IDA Sce S000005482
GO:0016151	nickel ion binding	F	ISO Mmu MGI:1345279
GO:0030145	manganese ion binding	F	ISO Mmu MGI:1345279
GO:0046870	cadmium ion binding	F	ISO Mmu MGI:1345279
GO:0046873	metal ion transmembrane transporter activity	F	ISS Ath At4g18790 At1g47240 Sce S000004024 NAS Ath At1g47240 At4g18790 TAS Ath At5g67330 At1g80830 At2g23150
GO:0050897	cobalt ion binding	F	ISO Mmu MGI:1345279
GO:0000041	transition metal ion transport	P	IMP Dme FBgn0011672 ISO Mmu MGI:1345279
GO:0000060	protein import into nucleus, translocation	P	IMP Mmu MGI:1345275
GO:0000165	MAPKKK cascade	P	ISO Mmu MGI:1345275
GO:0001818	negative regulation of cytokine production	P	IMP Mmu MGI:1345275
GO:0001819	positive regulation of cytokine production	P	IMP Mmu MGI:1345275
GO:0002309	T cell proliferation involved in immune response	P	IMP Mmu MGI:1345275
GO:0002369	T cell cytokine production	P	IMP Mmu MGI:1345275
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	P	IMP Mmu MGI:1345275
GO:0002827	positive regulation of T-helper 1 type immune response	P	IMP Mmu MGI:1345275
GO:0006778	porphyrin metabolic process	P	IMP Mmu MGI:1345279
GO:0006779	porphyrin biosynthetic process	P	IMP Mmu MGI:1345279
GO:0006783	heme biosynthetic process	P	IMP Mmu MGI:1345279
GO:0006824	cobalt ion transport	P	IDA Mmu MGI:1345279 IGI Sce S000001092
GO:0006825	copper ion transport	P	IGI Sce S000005482 IMP Dme FBgn0011672
GO:0006826	iron ion transport	P	IDA Mmu MGI:1345279 IGI Sce S000005482 IMP Mmu MGI:1345279 MGI:1345275 Sce S000004024
GO:0006828	manganese ion transport	P	IMP Ath At5g67330 At2g23150 Mmu MGI:1345275 Sce S000001092 S000005482 TAS Ath At1g80830 At2g23150 At5g67330
GO:0006875	cellular metal ion homeostasis	P	NAS Ath At1g80830 At1g47240 At4g18790 At5g67330 At2g23150
GO:0006876	cellular cadmium ion homeostasis	P	IGI Sce S000005482
GO:0006877	cellular cobalt ion homeostasis	P	IGI Sce S000001092
GO:0006878	cellular copper ion homeostasis	P	IGI Sce S000005482
GO:0006879	cellular iron ion homeostasis	P	IGI Ath At5g67330 IMP Mmu MGI:1345275 Sce S000004024
GO:0006909	phagocytosis	P	IMP Mmu MGI:1345275
GO:0006950	response to stress	P	IMP Cel WBGene00004878
GO:0006954	inflammatory response	P	IMP Mmu MGI:1345275
GO:0007035	vacuolar acidification	P	IMP Mmu MGI:1345275
GO:0007611	learning or memory	P	IMP Mmu MGI:1345279
GO:0009617	response to bacterium	P	IEP Ath At2g23150 IMP Mmu MGI:1345275
GO:0009624	response to nematode	P	IEP Ath At5g67330
GO:0010039	response to iron ion	P	IEP Ath At5g67330
GO:0010042	response to manganese ion	P	ISO Mmu MGI:1345279
GO:0010043	response to zinc ion	P	IEP Ath At2g23150
GO:0010467	gene expression	P	IMP Cel WBGene00004878 WBGene00004876
GO:0010628	positive regulation of gene expression	P	IMP Mmu MGI:1345275
GO:0010670	positive regulation of oxygen and reactive oxygen species metabolic process	P	IGI Ath At2g23150 At5g67330
GO:0015674	di-, tri-valent inorganic cation transport	P	TAS Spo SPAC27F1.08
GO:0015677	copper ion import	P	IMP Dme FBgn0011672
GO:0015684	ferrous iron transport	P	IDA Mmu MGI:1345279 ISO Mmu MGI:1345279
GO:0015691	cadmium ion transport	P	IGI Sce S000005482 TAS Ath At1g80830 At5g67330 At2g23150
GO:0015692	lead ion transport	P	TAS Ath At1g80830 At5g67330 At2g23150
GO:0015707	nitrite transport	P	IDA Mmu MGI:1345275
GO:0015992	proton transport	P	IDA Mmu MGI:1345279
GO:0019725	cellular homeostasis	P	IMP Cel WBGene00004877 WBGene00004878 WBGene00004876
GO:0030001	metal ion transport	P	ISS Ath At1g47240 At4g18790 NAS Ath At1g47240 At4g18790 TAS Ath At1g80830 At5g67330 At2g23150
GO:0030026	cellular manganese ion homeostasis	P	IGI Spo SPAC27F1.08 IMP Sce S000005482 S000001092
GO:0032147	activation of protein kinase activity	P	IMP Mmu MGI:1345275
GO:0032496	response to lipopolysaccharide	P	IDA Mmu MGI:1345275 IMP Mmu MGI:1345275 ISO Mmu MGI:1345275
GO:0032623	interleukin-2 production	P	IMP Mmu MGI:1345275
GO:0032632	interleukin-3 production	P	IMP Mmu MGI:1345275
GO:0032729	positive regulation of interferon-gamma production	P	IMP Mmu MGI:1345275
GO:0034341	response to interferon-gamma	P	IDA Mmu MGI:1345275
GO:0034755	iron ion transmembrane transport	P	IGI Ath At1g80830
GO:0042060	wound healing	P	IMP Mmu MGI:1345275
GO:0042116	macrophage activation	P	IDA Mmu MGI:1345275 IMP Mmu MGI:1345275
GO:0042742	defense response to bacterium	P	IMP Ath At2g23150 At5g67330 Mmu MGI:1345275
GO:0042832	defense response to protozoan	P	IMP Mmu MGI:1345275
GO:0043091	L-arginine import	P	IDA Mmu MGI:1345275
GO:0045342	MHC class II biosynthetic process	P	IMP Mmu MGI:1345275
GO:0045730	respiratory burst	P	IDA Mmu MGI:1345275
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IMP Mmu MGI:1345275
GO:0048002	antigen processing and presentation of peptide antigen	P	IMP Mmu MGI:1345275
GO:0048255	mRNA stabilization	P	IMP Mmu MGI:1345275
GO:0048813	dendrite morphogenesis	P	IMP Mmu MGI:1345279
GO:0048821	erythrocyte development	P	IMP Mmu MGI:1345279
GO:0050766	positive regulation of phagocytosis	P	IMP Mmu MGI:1345275
GO:0050829	defense response to Gram-negative bacterium	P	IMP Mmu MGI:1345275
GO:0050916	sensory perception of sweet taste	P	IMP Dme FBgn0011672
GO:0055070	copper ion homeostasis	P	IMP Dme FBgn0011672
GO:0055071	manganese ion homeostasis	P	IMP Ath At1g80830
GO:0055072	iron ion homeostasis	P	IMP Ath At5g67330 At2g23150 Mmu MGI:1345275
GO:0055076	transition metal ion homeostasis	P	IMP Dme FBgn0011672
GO:0060586	multicellular organismal iron ion homeostasis	P	IMP Mmu MGI:1345275 MGI:1345279
GO:0070627	ferrous iron import	P	IDA Mmu MGI:1345279 IMP Mmu MGI:1345279
GO:0070838	divalent metal ion transport	P	IGI Dme FBgn0011672
GO:0070839	divalent metal ion export	P	IDA Mmu MGI:1345275
GO:0071421	manganese ion transmembrane transport	P	IMP Mmu MGI:1345275 Spo SPAC27F1.08

Curated yeast ortholog results:

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC27F1.08 (Q10177)	YHR050W (S000001092)

GO terms for curated homolog results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005739	mitochondrion	C	IDA Sce S000001092
GO:0005783	endoplasmic reticulum	C	IDA Spo SPAC27F1.08
GO:0016023	cytoplasmic membrane-bounded vesicle	C	IDA Sce S000001092
GO:0030176	integral to endoplasmic reticulum membrane	C	IC Spo SPAC27F1.08
GO:0005384	manganese ion transmembrane transporter activity	F	TAS Spo SPAC27F1.08
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	F	IDA Sce S000001092
GO:0006824	cobalt ion transport	P	IGI Sce S000001092
GO:0006828	manganese ion transport	P	IMP Sce S000001092
GO:0006877	cellular cobalt ion homeostasis	P	IGI Sce S000001092
GO:0015674	di-, tri-valent inorganic cation transport	P	TAS Spo SPAC27F1.08
GO:0030026	cellular manganese ion homeostasis	P	IGI Spo SPAC27F1.08 IMP Sce S000001092
GO:0071421	manganese ion transmembrane transport	P	IMP Spo SPAC27F1.08