Bahler Lab

Search term: YHR057C

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name CPR2

SGD link S000001099

Alternative ID YHR057C

Description Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway

Synonyms YHR057C

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0880 ACDHYP-

KOGs classification KOGs description

CELLULAR PROCESSES AND SIGNALING Peptidyl-prolyl cis-trans isomerase

Species KOG link NCBI link UniProt link

Arabidopsis thaliana (Ath) At3g62030 GI:15228674

Arabidopsis thaliana (Ath) At5g13120 GI:15240008

Caenorhabditis elegans (Cel) CE01301
(WBGene00000882) GI:17552780 P52014

Caenorhabditis elegans (Cel) CE17730
(WBGene00000881) GI:17506307 P52013

Drosophila melanogaster (Dme) 7291447
(FBgn0034753) GI:20130249

Drosophila melanogaster (Dme) 7296144
(FBgn0002936) GI:17136360 P15425

Homo sapiens (Hsa) Hs4505991
(PPIC) GI:4505991 P45877

Homo sapiens (Hsa) Hs4758950
(PPIB) GI:4758950 P23284

Saccharomyces cerevisiae (Sce) YCR069w
(S000000665) GI:6319914 P25334

Saccharomyces cerevisiae (Sce) YDR304c
(S000002712) GI:6320510 P35176

Saccharomyces cerevisiae (Sce) YHR057c
(S000001099) GI:6321848 P23285

Saccharomyces cerevisiae (Sce) YNR028w
(S000005311) GI:6324355 P53728

Schizosaccharomyces pombe (Spo) SPBP8B7.25 GI:19113324 O94273

Arabidopsis thaliana (Ath) At3g62030 GI:15228674

Arabidopsis thaliana (Ath) At5g13120 GI:15240008

Caenorhabditis elegans (Cel) CE01301
(WBGene00000882) GI:17552780 P52014

Caenorhabditis elegans (Cel) CE17730
(WBGene00000881) GI:17506307 P52013

Drosophila melanogaster (Dme) 7291447
(FBgn0034753) GI:20130249

Drosophila melanogaster (Dme) 7296144
(FBgn0002936) GI:17136360 P15425

Homo sapiens (Hsa) Hs4505991
(PPIC) GI:4505991 P45877

Homo sapiens (Hsa) Hs4758950
(PPIB) GI:4758950 P23284

Saccharomyces cerevisiae (Sce) YCR069w
(S000000665) GI:6319914 P25334

Saccharomyces cerevisiae (Sce) YDR304c
(S000002712) GI:6320510 P35176

Saccharomyces cerevisiae (Sce) YHR057c
(S000001099) GI:6321848 P23285

Saccharomyces cerevisiae (Sce) YNR028w
(S000005311) GI:6324355 P53728

Schizosaccharomyces pombe (Spo) SPBP8B7.25 GI:19113324 O94273

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0000324 fungal-type vacuole C
IDA
Sce S000005311

GO:0005575 cellular_component C
ND
Sce S000001099

GO:0005624 membrane fraction C
IDA
Dme FBgn0002936

GO:0005737 cytoplasm C
IDA
Sce S000002712

GO:0005783 endoplasmic reticulum C
IDA
Sce S000002712
Spo SPBP8B7.25

GO:0005788 endoplasmic reticulum lumen C
IDA
Dme FBgn0002936
ISS
Spo SPBP8B7.25
NAS
Hsa PPIB

GO:0005794 Golgi apparatus C
IDA
Spo SPBP8B7.25

GO:0005811 lipid particle C
IDA
Dme FBgn0034753

GO:0005875 microtubule associated complex C
IDA
Dme FBgn0034753

GO:0005887 integral to plasma membrane C
NAS
Dme FBgn0002936

GO:0009507 chloroplast C
IDA
Ath At3g62030
At5g13120

GO:0009533 chloroplast stromal thylakoid C
IDA
Ath At5g13120

GO:0009535 chloroplast thylakoid membrane C
IDA
Ath At3g62030
At5g13120

GO:0009543 chloroplast thylakoid lumen C
IDA
Ath At5g13120

GO:0009570 chloroplast stroma C
IDA
Ath At3g62030

GO:0009579 thylakoid C
IDA
Ath At3g62030
At5g13120

GO:0009941 chloroplast envelope C
IDA
Ath At3g62030

GO:0016020 membrane C
ISS
Sce S000000665

GO:0016021 integral to membrane C
IDA
Dme FBgn0002936

GO:0016023 cytoplasmic membrane-bounded vesicle C
IDA
Dme FBgn0002936

GO:0022626 cytosolic ribosome C
IDA
Ath At3g62030

GO:0031977 thylakoid lumen C
IDA
Ath At5g13120
At3g62030

GO:0048046 apoplast C
IDA
Ath At3g62030

GO:0003755 peptidyl-prolyl cis-trans isomerase
activity F
IDA
Ath At3g62030
Sce S000001099
IMP
Ath At5g13120
ISS
Ath At5g13120
At3g62030
Dme FBgn0002936
FBgn0034753
Sce S000005311
S000002712
S000000665
NAS
Dme FBgn0002936
Hsa PPIB
TAS
Dme FBgn0002936

GO:0005515 protein binding F
IPI
Hsa PPIB

GO:0016018 cyclosporin A binding F
IMP
Dme FBgn0002936
TAS
Hsa PPIC

GO:0051082 unfolded protein binding F
TAS
Hsa PPIB
PPIC

GO:0006457 protein folding P
ISS
Ath At3g62030
At5g13120

GO:0006458 'de novo' protein folding P
NAS
Dme FBgn0002936
TAS
Dme FBgn0002936

GO:0006810 transport P
TAS
Dme FBgn0002936

GO:0006979 response to oxidative stress P
IMP
Ath At3g62030

GO:0007039 vacuolar protein catabolic process P
RCA
Sce S000000665

GO:0007165 signal transduction P
ISS
Ath At3g62030
TAS
Hsa PPIC

GO:0007602 phototransduction P
IPI
Dme FBgn0002936
NAS
Dme FBgn0002936
TAS
Dme FBgn0002936

GO:0007603 phototransduction, visible light P
IMP
Dme FBgn0002936

GO:0008150 biological_process P
ND
Sce S000001099
S000002712
S000005311
S000000665

GO:0009642 response to light intensity P
IMP
Ath At3g62030

GO:0009651 response to salt stress P
IMP
Ath At3g62030

GO:0009737 response to abscisic acid stimulus P
IEP
Ath At3g62030

GO:0010275 NAD(P)H dehydrogenase complex assembly P
IMP
Ath At5g13120

GO:0010555 response to mannitol stimulus P
IMP
Ath At3g62030

GO:0016063 rhodopsin biosynthetic process P
IMP
Dme FBgn0002936
NAS
Dme FBgn0002936
TAS
Dme FBgn0002936

GO:0019344 cysteine biosynthetic process P
IMP
Ath At3g62030

GO:0042742 defense response to bacterium P
IEP
Ath At3g62030

GO:0070059 apoptosis in response to endoplasmic reticulum
stress P
IMP
Dme FBgn0002936

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

727

Species Gene ID NCBI link UniProt link

Homo sapiens (Hsa) PPIC GI:4505991 P45877

Canis familiaris (Cfa) PPIC GI:73970864

Mus musculus (Mmu) Ppic
(MGI:97751) GI:6679441 P30412

Rattus norvegicus (Rno) Ppic
(RGD:1303221) GI:51948402

Gallus gallus (Gga) PPIC GI:118104631

Saccharomyces cerevisiae (Sce) CPR2
(S000001099) GI:6321848 P23285

Arabidopsis thaliana (Ath) ROC4 GI:15228674

Oryza sativa (Osa) Os01g0284700 GI:115436026

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Sce S000001099

GO:0009507 chloroplast C
IDA
Ath ROC4

GO:0009535 chloroplast thylakoid membrane C
IDA
Ath ROC4

GO:0009570 chloroplast stroma C
IDA
Ath ROC4

GO:0009579 thylakoid C
IDA
Ath ROC4

GO:0009941 chloroplast envelope C
IDA
Ath ROC4

GO:0022626 cytosolic ribosome C
IDA
Ath ROC4

GO:0031977 thylakoid lumen C
IDA
Ath ROC4

GO:0048046 apoplast C
IDA
Ath ROC4

GO:0003755 peptidyl-prolyl cis-trans isomerase
activity F
IDA
Ath ROC4
Sce S000001099
ISS
Ath ROC4

GO:0016018 cyclosporin A binding F
TAS
Hsa PPIC

GO:0051082 unfolded protein binding F
TAS
Hsa PPIC

GO:0006457 protein folding P
ISS
Ath ROC4

GO:0006979 response to oxidative stress P
IMP
Ath ROC4

GO:0007165 signal transduction P
ISS
Ath ROC4
TAS
Hsa PPIC

GO:0008150 biological_process P
ND
Sce S000001099

GO:0009642 response to light intensity P
IMP
Ath ROC4

GO:0009651 response to salt stress P
IMP
Ath ROC4

GO:0009737 response to abscisic acid stimulus P
IEP
Ath ROC4

GO:0010555 response to mannitol stimulus P
IMP
Ath ROC4

GO:0019344 cysteine biosynthetic process P
IMP
Ath ROC4

GO:0042742 defense response to bacterium P
IEP
Ath ROC4

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KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0880	ACDHYP-

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALING	Peptidyl-prolyl cis-trans isomerase

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At3g62030	GI:15228674
Arabidopsis thaliana (Ath)	At5g13120	GI:15240008
Caenorhabditis elegans (Cel)	CE01301 (WBGene00000882)	GI:17552780	P52014
Caenorhabditis elegans (Cel)	CE17730 (WBGene00000881)	GI:17506307	P52013
Drosophila melanogaster (Dme)	7291447 (FBgn0034753)	GI:20130249
Drosophila melanogaster (Dme)	7296144 (FBgn0002936)	GI:17136360	P15425
Homo sapiens (Hsa)	Hs4505991 (PPIC)	GI:4505991	P45877
Homo sapiens (Hsa)	Hs4758950 (PPIB)	GI:4758950	P23284
Saccharomyces cerevisiae (Sce)	YCR069w (S000000665)	GI:6319914	P25334
Saccharomyces cerevisiae (Sce)	YDR304c (S000002712)	GI:6320510	P35176
Saccharomyces cerevisiae (Sce)	YHR057c (S000001099)	GI:6321848	P23285
Saccharomyces cerevisiae (Sce)	YNR028w (S000005311)	GI:6324355	P53728
Schizosaccharomyces pombe (Spo)	SPBP8B7.25	GI:19113324	O94273
Arabidopsis thaliana (Ath)	At3g62030	GI:15228674
Arabidopsis thaliana (Ath)	At5g13120	GI:15240008
Caenorhabditis elegans (Cel)	CE01301 (WBGene00000882)	GI:17552780	P52014
Caenorhabditis elegans (Cel)	CE17730 (WBGene00000881)	GI:17506307	P52013
Drosophila melanogaster (Dme)	7291447 (FBgn0034753)	GI:20130249
Drosophila melanogaster (Dme)	7296144 (FBgn0002936)	GI:17136360	P15425
Homo sapiens (Hsa)	Hs4505991 (PPIC)	GI:4505991	P45877
Homo sapiens (Hsa)	Hs4758950 (PPIB)	GI:4758950	P23284
Saccharomyces cerevisiae (Sce)	YCR069w (S000000665)	GI:6319914	P25334
Saccharomyces cerevisiae (Sce)	YDR304c (S000002712)	GI:6320510	P35176
Saccharomyces cerevisiae (Sce)	YHR057c (S000001099)	GI:6321848	P23285
Saccharomyces cerevisiae (Sce)	YNR028w (S000005311)	GI:6324355	P53728
Schizosaccharomyces pombe (Spo)	SPBP8B7.25	GI:19113324	O94273

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	PPIC	GI:4505991	P45877
Canis familiaris (Cfa)	PPIC	GI:73970864
Mus musculus (Mmu)	Ppic (MGI:97751)	GI:6679441	P30412
Rattus norvegicus (Rno)	Ppic (RGD:1303221)	GI:51948402
Gallus gallus (Gga)	PPIC	GI:118104631
Saccharomyces cerevisiae (Sce)	CPR2 (S000001099)	GI:6321848	P23285
Arabidopsis thaliana (Ath)	ROC4	GI:15228674
Oryza sativa (Osa)	Os01g0284700	GI:115436026