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Search term: YHR073W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name OSH3
SGD link S000001115
Alternative ID YHR073W
Description Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
Synonyms YHR073W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1737 ACDHYP-

KOGs classification KOGs description
METABOLISM Oxysterol-binding protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g13170 GI:15222204
Arabidopsis thaliana (Ath) At1g77730 GI:15217449
Arabidopsis thaliana (Ath) At2g31020 GI:15224597
Arabidopsis thaliana (Ath) At2g31030 GI:15224598
Arabidopsis thaliana (Ath) At3g09300 GI:15232633
Arabidopsis thaliana (Ath) At4g08180 GI:15236424
Arabidopsis thaliana (Ath) At4g12460 GI:15235381
Arabidopsis thaliana (Ath) At4g22540 GI:7486604
Arabidopsis thaliana (Ath) At5g02100 GI:15241681
Arabidopsis thaliana (Ath) At5g59420 GI:15238398
Caenorhabditis elegans (Cel) CE26105
(WBGene00012930)
GI:17555950 Q9U2C7
Caenorhabditis elegans (Cel) CE28126 GI:17555948 Q9U2C7
Drosophila melanogaster (Dme) 7301240
(FBgn0020626)
GI:17137400
Homo sapiens (Hsa) Hs13540513
(OSBP2)
GI:13540513 Q8NA37
Homo sapiens (Hsa) Hs14149704
(OSBPL3)
GI:14149704 Q8NFH1
Homo sapiens (Hsa) Hs14210532
(OSBPL6)
GI:14210532 Q9BZF3
Homo sapiens (Hsa) Hs21735580 GI:20531135 Q8NFH1
Homo sapiens (Hsa) Hs21735582 GI:20531137 Q8NFH1
Homo sapiens (Hsa) Hs21735584 GI:20531139 Q8NFH1
Homo sapiens (Hsa) Hs21735586 GI:20531141 Q8NFH1
Homo sapiens (Hsa) Hs21735588 GI:20531143 Q8NFH1
Homo sapiens (Hsa) Hs22035612 GI:22035612 Q9BZF3
Homo sapiens (Hsa) Hs22035614 GI:20139132 Q8WXP9
Homo sapiens (Hsa) Hs4505531
(OSBP)
GI:4505531 P22059
Homo sapiens (Hsa) HsM19923507 GI:19923507
Saccharomyces cerevisiae (Sce) YAR044w GI:6319339
Saccharomyces cerevisiae (Sce) YDL019c
(S000002177)
GI:6320185 Q12451
Saccharomyces cerevisiae (Sce) YHR073w
(S000001115)
GI:6321864 P38713
Schizosaccharomyces pombe (Spo) SPAC23H4.01c GI:19114317 O13944
Schizosaccharomyces pombe (Spo) SPBC2F12.05c_2 GI:19112502 O14340


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g08180
At4g22540
At2g31030
At5g59420
At4g12460
GO:0005737 cytoplasm C
IDA
SceS000001115
SpoSPBC2F12.05c
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g02100
SceS000002177
ISS
SpoSPBC2F12.05c
SPAC23H4.01c
GO:0005829 cytosol C
IDA
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0005886 plasma membrane C
IDA
SceS000002177
GO:0005935 cellular bud neck C
IDA
SceS000002177
GO:0043234 protein complex C
NAS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0005515 protein binding F
IPI
HsaOSBPL3
GO:0005545 phosphatidylinositol binding F
ISS
SceS000002177
S000001115
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0008142 oxysterol binding F
ISS
AthAt2g31030
At3g09300
At4g08180
At2g31020
At1g13170
At5g02100
At4g22540
At5g59420
At4g12460
DmeFBgn0020626
SceS000001115
S000002177
SpoSPAC23H4.01c
SPBC2F12.05c
NAS
DmeFBgn0020626
TAS
HsaOSBP
GO:0032934 sterol binding F
IDA
AthAt5g02100
GO:0035091 phosphoinositide binding F
ISS
AthAt4g08180
At4g22540
At1g77730
GO:0000742 karyogamy involved in conjugation with cellular
fusion
P
IGI
SceS000001115
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000001115
GO:0006887 exocytosis P
IGI
SceS000001115
S000002177
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0006897 endocytosis P
IGI
SceS000001115
S000002177
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0007124 pseudohyphal growth P
IMP
SceS000001115
GO:0007165 signal transduction P
ISS
AthAt4g08180
At1g77730
At4g22540
GO:0008202 steroid metabolic process P
ISS
AthAt1g13170
At4g22540
At3g09300
At4g08180
At2g31020
At5g59420
At5g02100
At4g12460
At2g31030
GO:0009567 double fertilization forming a zygote and
endosperm
P
IMP
AthAt5g02100
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00012930
GO:0015918 sterol transport P
IGI
SceS000002177
S000001115
IMP
SceS000001115
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0030011 maintenance of cell polarity P
IGI
SceS000001115
S000002177
GO:0033554 cellular response to stress P
IEP
SpoSPBC2F12.05c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
115616

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAP27G11.01 GI:63054541
Saccharomyces cerevisiae (Sce) OSH3
(S000001115)
GI:6321864 P38713
Kluyveromyces lactis (Kla) KLLA0C16797g GI:50305981
Eremothecium gossypii (Ego) AGOS_AGR356W GI:45201452
Magnaporthe grisea (Mgr) MGG_11490 GI:145610925
Neurospora crassa (Ncr) NCU04610.1 GI:32406706


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001115
GO:0005545 phosphatidylinositol binding F
ISS
SceS000001115
GO:0008142 oxysterol binding F
ISS
SceS000001115
GO:0000742 karyogamy involved in conjugation with cellular
fusion
P
IGI
SceS000001115
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000001115
GO:0006887 exocytosis P
IGI
SceS000001115
GO:0006897 endocytosis P
IGI
SceS000001115
GO:0007124 pseudohyphal growth P
IMP
SceS000001115
GO:0015918 sterol transport P
IGI
SceS000001115
IMP
SceS000001115
GO:0030011 maintenance of cell polarity P
IGI
SceS000001115

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1496

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4667 AGR356W
Arabidopsis thaliana (Ath) ath1383 At1g13170.1
Candida glabrata (Cgl) cgl3465 CAGL0J10780g
Debaryomyces hansenii (Dha) dha6533 DEHA0G18623g
Danio rerio (Dre) dre7037 ENSDARP00000012286
Danio rerio (Dre) dre7038 ENSDARP00000038943
Danio rerio (Dre) dre7034 ENSDARP00000042922
Danio rerio (Dre) dre7036 ENSDARP00000043760
Danio rerio (Dre) dre9867 ENSDARP00000043772
Danio rerio (Dre) dre9866 ENSDARP00000045242
Danio rerio (Dre) dre9869 ENSDARP00000047128
Danio rerio (Dre) dre7035 ENSDARP00000047225
Danio rerio (Dre) dre9868 ENSDARP00000048651
Takifugu rubripes (Fru) fru7985 SINFRUP00000145266
Takifugu rubripes (Fru) fru7986 SINFRUP00000145267
Takifugu rubripes (Fru) fru22222 SINFRUP00000159147
Takifugu rubripes (Fru) fru22220 SINFRUP00000159148
Takifugu rubripes (Fru) fru22219 SINFRUP00000159149
Takifugu rubripes (Fru) fru22221 SINFRUP00000159150
Takifugu rubripes (Fru) fru7984 SINFRUP00000165759
Takifugu rubripes (Fru) fru7983 SINFRUP00000167450
Takifugu rubripes (Fru) fru7987 SINFRUP00000171284
Gallus gallus (Gga) gga9865 ENSGALP00000017901
Gallus gallus (Gga) gga9862 ENSGALP00000017902
(OSBPL3)
Gallus gallus (Gga) gga9863 ENSGALP00000017903
(OSBPL6)
Gallus gallus (Gga) gga9864 ENSGALP00000017904
(OSBPL3)
Homo sapiens (Hsa) hsa28342 ENSP00000315277
(OSBPL3)
Q9H4L5-3
Homo sapiens (Hsa) hsa28343 ENSP00000315331
(OSBPL3)
Q9H4L5-2
Homo sapiens (Hsa) hsa28341 ENSP00000315410
(OSBPL3)
Q9H4L5-1
Kluyveromyces lactis (Kla) kla1950 KLLA0C16797g
Mus musculus (Mmu) mmu21854 ENSMUSP00000002807
Mus musculus (Mmu) mmu21853 ENSMUSP00000071643
(MGI:1918970)
Q80UX3
Neurospora crassa (Ncr) ncr4478 NCU04610.2
Oryza sativa (Osa) osa69608 7083.m00106
Rattus norvegicus (Rno) rno21250 ENSRNOP00000013828
(RGD:1564287)
Rattus norvegicus (Rno) rno21251 ENSRNOP00000035241
(RGD:1564287)
Rattus norvegicus (Rno) rno21252 ENSRNOP00000048628
(RGD:1564287)
Saccharomyces cerevisiae (Sce) sce2836 YHR073W
(S000001115)
Schizosaccharomyces pombe (Spo) spo2707 SPAC23H4.01c O13944
Yarrowia lipolytica (Yli) yli4800 YALI0E22781g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1918970
GO:0005737 cytoplasm C
IDA
SceS000001115
GO:0005783 endoplasmic reticulum C
ISS
SpoSPAC23H4.01c
GO:0005829 cytosol C
IDA
SpoSPAC23H4.01c
GO:0043234 protein complex C
NAS
SpoSPAC23H4.01c
GO:0003674 molecular_function F
ND
MmuMGI:1918970
GO:0005545 phosphatidylinositol binding F
ISS
SceS000001115
SpoSPAC23H4.01c
GO:0008142 oxysterol binding F
ISS
AthAt1g13170
SceS000001115
SpoSPAC23H4.01c
GO:0000742 karyogamy involved in conjugation with cellular
fusion
P
IGI
SceS000001115
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000001115
GO:0006887 exocytosis P
IGI
SceS000001115
ISS
SpoSPAC23H4.01c
GO:0006897 endocytosis P
IGI
SceS000001115
ISS
SpoSPAC23H4.01c
GO:0007124 pseudohyphal growth P
IMP
SceS000001115
GO:0008150 biological_process P
ND
MmuMGI:1918970
GO:0008202 steroid metabolic process P
ISS
AthAt1g13170
GO:0015918 sterol transport P
IGI
SceS000001115
IMP
SceS000001115
ISS
SpoSPAC23H4.01c
GO:0030011 maintenance of cell polarity P
IGI
SceS000001115

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC2F12.05c
(O14340)
YHR073W
(S000001115)
SPAC23H4.01c
(O13944)
YHR073W
(S000001115)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001115
SpoSPBC2F12.05c
GO:0005783 endoplasmic reticulum C
ISS
SpoSPBC2F12.05c
SPAC23H4.01c
GO:0005829 cytosol C
IDA
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0043234 protein complex C
NAS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0005545 phosphatidylinositol binding F
ISS
SceS000001115
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0008142 oxysterol binding F
ISS
SceS000001115
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0000742 karyogamy involved in conjugation with cellular
fusion
P
IGI
SceS000001115
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000001115
GO:0006887 exocytosis P
IGI
SceS000001115
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0006897 endocytosis P
IGI
SceS000001115
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0007124 pseudohyphal growth P
IMP
SceS000001115
GO:0015918 sterol transport P
IGI
SceS000001115
IMP
SceS000001115
ISS
SpoSPAC23H4.01c
SPBC2F12.05c
GO:0030011 maintenance of cell polarity P
IGI
SceS000001115
GO:0033554 cellular response to stress P
IEP
SpoSPBC2F12.05c

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GO info in one table:

s.khadayate@ucl.ac.uk