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Search term: YHR108W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GGA2
SGD link S000001150
Alternative ID YHR108W
Description Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi
Synonyms YHR108W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1087 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cytosolic sorting protein GGA2/TOM1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g06210 GI:18390626
Arabidopsis thaliana (Ath) At1g21380 GI:18394983
Arabidopsis thaliana (Ath) At1g76970 GI:15223805
Arabidopsis thaliana (Ath) At2g38410 GI:15224501
Arabidopsis thaliana (Ath) At3g08790 GI:15231966
Arabidopsis thaliana (Ath) At4g32760 GI:15233916
Arabidopsis thaliana (Ath) At5g01760 GI:15241058
Arabidopsis thaliana (Ath) At5g16880 GI:15237869
Arabidopsis thaliana (Ath) At5g63640 GI:15242856
Caenorhabditis elegans (Cel) CE25764
(WBGene00015561)		 GI:17550228 Q95QX5
Caenorhabditis elegans (Cel) CE27055 GI:17550226 Q95QX5
Drosophila melanogaster (Dme) 7294938 GI:7294938
Homo sapiens (Hsa) Hs4885637 GI:4885637 O43601
Homo sapiens (Hsa) Hs4885639 GI:4885639
Homo sapiens (Hsa) Hs21389575 GI:18586693
Homo sapiens (Hsa) Hs20336264 GI:20336264
Homo sapiens (Hsa) Hs20336267
(GGA3)		 GI:20336267 Q9NZ52
Saccharomyces cerevisiae (Sce) YDR358w
(S000002766)		 GI:6320565 Q06336
Saccharomyces cerevisiae (Sce) YHR108w
(S000001150)		 GI:6321900 P38817
Schizosaccharomyces pombe (Spo) SPAC1F3.05 GI:19113920 Q10410
Schizosaccharomyces pombe (Spo) SPBC25H2.16c GI:19113143 P87157
Schizosaccharomyces pombe (Spo) SPBC31F10.07 GI:19113361 P87308
Arabidopsis thaliana (Ath) At1g06210 GI:18390626
Arabidopsis thaliana (Ath) At1g21380 GI:18394983
Arabidopsis thaliana (Ath) At1g76970 GI:15223805
Arabidopsis thaliana (Ath) At2g38410 GI:15224501
Arabidopsis thaliana (Ath) At3g08790 GI:15231966
Arabidopsis thaliana (Ath) At4g32760 GI:15233916
Arabidopsis thaliana (Ath) At5g01760 GI:15241058
Arabidopsis thaliana (Ath) At5g16880 GI:15237869
Arabidopsis thaliana (Ath) At5g63640 GI:15242856
Caenorhabditis elegans (Cel) CE25764
(WBGene00015561)		 GI:17550228 Q95QX5
Caenorhabditis elegans (Cel) CE27055 GI:17550226 Q95QX5
Drosophila melanogaster (Dme) 7294938 GI:7294938
Homo sapiens (Hsa) Hs4885637 GI:4885637 O43601
Homo sapiens (Hsa) Hs4885639 GI:4885639
Homo sapiens (Hsa) Hs21389575 GI:18586693
Homo sapiens (Hsa) Hs20336264 GI:20336264
Homo sapiens (Hsa) Hs20336267
(GGA3)		 GI:20336267 Q9NZ52
Saccharomyces cerevisiae (Sce) YDR358w
(S000002766)		 GI:6320565 Q06336
Saccharomyces cerevisiae (Sce) YHR108w
(S000001150)		 GI:6321900 P38817
Schizosaccharomyces pombe (Spo) SPAC1F3.05 GI:19113920 Q10410
Schizosaccharomyces pombe (Spo) SPBC25H2.16c GI:19113143 P87157
Schizosaccharomyces pombe (Spo) SPBC31F10.07 GI:19113361 P87308


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1F3.05
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1F3.05
SPBC25H2.16c
GO:0005795 Golgi stack C
ISS
AthAt1g21380
At1g76970
At3g08790
At5g63640
At2g38410
At1g06210
At5g01760
At5g16880
At4g32760
GO:0005802 trans-Golgi network C
IDA
HsaGGA3
SceS000001150
S000002766
ISS
SpoSPAC1F3.05
SPBC25H2.16c
GO:0005816 spindle pole body C
IDA
SpoSPBC31F10.07
GO:0005829 cytosol C
IDA
SpoSPAC1F3.05
GO:0005886 plasma membrane C
IDA
AthAt5g63640
At2g38410
At5g16880
At4g32760
GO:0005938 cell cortex C
IDA
SpoSPBC31F10.07
ISS
SpoSPBC31F10.07
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000001150
S000002766
GO:0030135 coated vesicle C
RCA
SceS000001150
GO:0030136 clathrin-coated vesicle C
RCA
SceS000001150
GO:0030479 actin cortical patch C
ISS
SpoSPBC31F10.07
GO:0031410 cytoplasmic vesicle C
RCA
SceS000002766
S000001150
GO:0031982 vesicle C
RCA
SceS000002766
S000001150
GO:0031988 membrane-bounded vesicle C
RCA
SceS000002766
S000001150
GO:0003674 molecular_function F
ND
SpoSPBC31F10.07
SPAC1F3.05
SPBC25H2.16c
GO:0005515 protein binding F
IPI
HsaGGA3
GO:0008565 protein transporter activity F
ISS
AthAt2g38410
At1g76970
At3g08790
At1g21380
At5g63640
At5g01760
At4g32760
At1g06210
At5g16880
GO:0030306 ADP-ribosylation factor binding F
IDA
HsaGGA3
GO:0043130 ubiquitin binding F
IDA
SceS000002766
S000001150
IMP
SceS000001150
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000001150
IMP
SceS000001150
GO:0006886 intracellular protein transport P
IC
SpoSPBC25H2.16c
SPAC1F3.05
ISS
AthAt1g06210
At1g76970
At1g21380
At5g01760
At3g08790
At5g16880
At2g38410
At5g63640
At4g32760
NAS
HsaGGA3
GO:0006891 intra-Golgi vesicle-mediated transport P
ISS
AthAt5g63640
At2g38410
At4g32760
At1g76970
At3g08790
At5g16880
At5g01760
At1g21380
At1g06210
GO:0006895 Golgi to endosome transport P
IMP
SceS000002766
S000001150
GO:0006896 Golgi to vacuole transport P
IMP
SceS000002766
S000001150
IPI
SceS000001150
S000002766
ISS
SpoSPAC1F3.05
SPBC25H2.16c
GO:0006897 endocytosis P
ISS
SpoSPBC31F10.07
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002766
GO:0010687 site selection involved in cell cycle
cytokinesis		 P
ISS
SpoSPBC31F10.07
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002766
S000001150

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39250

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GGA1 GI:9558729 Q9UJY5
Pan troglodytes (Ptr) GGA1 GI:114686305
Canis familiaris (Cfa) GGA1 GI:73969169
Mus musculus (Mmu) Gga1
(MGI:2146207)		 GI:22122347 Q3TB03
Rattus norvegicus (Rno) Gga1
(RGD:1307770)		 GI:58865564
Gallus gallus (Gga) GGA1 GI:118082817
Drosophila melanogaster (Dme) Gga
(FBgn0030141)		 GI:18858097
Anopheles gambiae (Aga) AgaP_AGAP011568 GI:118780093
Schizosaccharomyces pombe (Spo) SPBC25H2.16c GI:19113143 P87157
Saccharomyces cerevisiae (Sce) GGA2
(S000001150)		 GI:6321900 P38817
Kluyveromyces lactis (Kla) KLLA0E21560g GI:50309817
Eremothecium gossypii (Ego) AGOS_AER243W GI:45190846
Magnaporthe grisea (Mgr) MGG_00852 GI:145610871
Neurospora crassa (Ncr) NCU06105.1 GI:32410959


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2146207
GO:0005737 cytoplasm C
IC
DmeFBgn0030141
GO:0005794 Golgi apparatus C
IDA
SpoSPBC25H2.16c
TAS
HsaGGA1
GO:0005802 trans-Golgi network C
IDA
SceS000001150
ISS
SpoSPBC25H2.16c
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000001150
GO:0030135 coated vesicle C
RCA
SceS000001150
GO:0030136 clathrin-coated vesicle C
RCA
SceS000001150
GO:0031410 cytoplasmic vesicle C
RCA
SceS000001150
GO:0031982 vesicle C
RCA
SceS000001150
GO:0031988 membrane-bounded vesicle C
RCA
SceS000001150
GO:0003674 molecular_function F
ND
HsaGGA1
SpoSPBC25H2.16c
GO:0005515 protein binding F
IPI
DmeFBgn0030141
HsaGGA1
MmuMGI:2146207
GO:0043130 ubiquitin binding F
IDA
SceS000001150
IMP
SceS000001150
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000001150
IMP
SceS000001150
GO:0006886 intracellular protein transport P
IC
SpoSPBC25H2.16c
TAS
HsaGGA1
GO:0006892 post-Golgi vesicle-mediated transport P
ISS
DmeFBgn0030141
GO:0006895 Golgi to endosome transport P
IMP
SceS000001150
GO:0006896 Golgi to vacuole transport P
IMP
SceS000001150
IPI
SceS000001150
ISS
SpoSPBC25H2.16c
GO:0008150 biological_process P
ND
MmuMGI:2146207
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000001150

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2888

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2745 AER243W
Candida glabrata (Cgl) cgl106 CAGL0A02629g
Cryptococcus neoformans (Cne) cne783 163.m03931
Debaryomyces hansenii (Dha) dha6451 DEHA0G16786g
Danio rerio (Dre) dre26288 ENSDARP00000035348
Danio rerio (Dre) dre26287 ENSDARP00000039926
Takifugu rubripes (Fru) fru7328 SINFRUP00000130398
Takifugu rubripes (Fru) fru7331 SINFRUP00000130400
Takifugu rubripes (Fru) fru6821 SINFRUP00000153243
Takifugu rubripes (Fru) fru6820 SINFRUP00000153244
Takifugu rubripes (Fru) fru6822 SINFRUP00000153247
Takifugu rubripes (Fru) fru7330 SINFRUP00000165892
Takifugu rubripes (Fru) fru6819 SINFRUP00000167439
Takifugu rubripes (Fru) fru7329 SINFRUP00000175069
Gallus gallus (Gga) gga16575 ENSGALP00000012957
Gallus gallus (Gga) gga16576 ENSGALP00000012958
Gallus gallus (Gga) gga16577 ENSGALP00000012959
Gallus gallus (Gga) gga16578 ENSGALP00000012960
Gallus gallus (Gga) gga16574 ENSGALP00000012961
(GGA3)		 Q5F496
Homo sapiens (Hsa) hsa14324 ENSP00000245541
(GGA3)		 Q9NZ52-1
Homo sapiens (Hsa) hsa14325 ENSP00000326575
(GGA3)		 Q9NZ52-2
Kluyveromyces lactis (Kla) kla3921 KLLA0E21560g
Mus musculus (Mmu) mmu5142 ENSMUSP00000019135
(MGI:2384159)		 A2A9W6
Rattus norvegicus (Rno) rno6433 ENSRNOP00000030297
(RGD:1309553)
Saccharomyces cerevisiae (Sce) sce1417 YDR358W
(S000002766)
Saccharomyces cerevisiae (Sce) sce2874 YHR108W
(S000001150)
Schizosaccharomyces pombe (Spo) spo3146 SPBC25H2.16c P87157
Yarrowia lipolytica (Yli) yli3853 YALI0D27192g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005794 Golgi apparatus C
IDA
SpoSPBC25H2.16c
GO:0005802 trans-Golgi network C
IDA
SceS000001150
S000002766
ISO
MmuMGI:2384159
ISS
SpoSPBC25H2.16c
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000001150
S000002766
GO:0030135 coated vesicle C
RCA
SceS000001150
GO:0030136 clathrin-coated vesicle C
RCA
SceS000001150
GO:0031410 cytoplasmic vesicle C
RCA
SceS000002766
S000001150
GO:0031982 vesicle C
RCA
SceS000002766
S000001150
GO:0031988 membrane-bounded vesicle C
RCA
SceS000002766
S000001150
GO:0003674 molecular_function F
ND
SpoSPBC25H2.16c
GO:0030306 ADP-ribosylation factor binding F
ISO
MmuMGI:2384159
GO:0043130 ubiquitin binding F
IDA
SceS000002766
S000001150
IMP
SceS000001150
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000001150
IMP
SceS000001150
GO:0006886 intracellular protein transport P
IC
SpoSPBC25H2.16c
GO:0006895 Golgi to endosome transport P
IMP
SceS000002766
S000001150
GO:0006896 Golgi to vacuole transport P
IMP
SceS000002766
S000001150
IPI
SceS000001150
S000002766
ISS
SpoSPBC25H2.16c
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002766
GO:0008150 biological_process P
ND
MmuMGI:2384159
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002766
S000001150

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC25H2.16c
(P87157)		 YHR108W
(S000001150)
SPAC1F3.05
(Q10410)		 YHR108W
(S000001150)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1F3.05
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1F3.05
SPBC25H2.16c
GO:0005802 trans-Golgi network C
IDA
SceS000001150
ISS
SpoSPAC1F3.05
SPBC25H2.16c
GO:0005829 cytosol C
IDA
SpoSPAC1F3.05
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000001150
GO:0030135 coated vesicle C
RCA
SceS000001150
GO:0030136 clathrin-coated vesicle C
RCA
SceS000001150
GO:0031410 cytoplasmic vesicle C
RCA
SceS000001150
GO:0031982 vesicle C
RCA
SceS000001150
GO:0031988 membrane-bounded vesicle C
RCA
SceS000001150
GO:0003674 molecular_function F
ND
SpoSPAC1F3.05
SPBC25H2.16c
GO:0043130 ubiquitin binding F
IDA
SceS000001150
IMP
SceS000001150
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000001150
IMP
SceS000001150
GO:0006886 intracellular protein transport P
IC
SpoSPBC25H2.16c
SPAC1F3.05
GO:0006895 Golgi to endosome transport P
IMP
SceS000001150
GO:0006896 Golgi to vacuole transport P
IMP
SceS000001150
IPI
SceS000001150
ISS
SpoSPAC1F3.05
SPBC25H2.16c
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000001150

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