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Search term: YHR119W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SET1
SGD link S000001161
Alternative ID YHR119W
Description Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain
Synonyms YHR119W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1080 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Histone H3 (Lys4) methyltransferase complex, subunit SET1 and related methyltransferases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g05830_2 GI:15221279
Arabidopsis thaliana (Ath) At2g31630 GI:15225109
Arabidopsis thaliana (Ath) At2g31640 GI:15225110
Arabidopsis thaliana (Ath) At3g61740 GI:15233199
Arabidopsis thaliana (Ath) At3g62500 GI:15228773
Arabidopsis thaliana (Ath) At4g15180 GI:15233719
Arabidopsis thaliana (Ath) At4g27910 GI:15234312
Arabidopsis thaliana (Ath) At5g28390_2 GI:15241785
Arabidopsis thaliana (Ath) At5g42400 GI:15238953
Arabidopsis thaliana (Ath) At5g53430 GI:15238735
Caenorhabditis elegans (Cel) CE01158 GI:17552316 Q18221
Caenorhabditis elegans (Cel) CE27735
(WBGene00004782)		 GI:17552318 Q18221
Caenorhabditis elegans (Cel) CE27736 GI:17552320 Q18221
Drosophila melanogaster (Dme) 7289568 GI:7289568
Homo sapiens (Hsa) Hs22059579 GI:22059579
Saccharomyces cerevisiae (Sce) YHR119w
(S000001161)		 GI:6321911 P38827
Schizosaccharomyces pombe (Spo) SPCC306.04c GI:19075312 Q9Y7R4
Arabidopsis thaliana (Ath) At1g05830_2 GI:15221279
Arabidopsis thaliana (Ath) At2g31630 GI:15225109
Arabidopsis thaliana (Ath) At2g31640 GI:15225110
Arabidopsis thaliana (Ath) At3g61740 GI:15233199
Arabidopsis thaliana (Ath) At3g62500 GI:15228773
Arabidopsis thaliana (Ath) At4g15180 GI:15233719
Arabidopsis thaliana (Ath) At4g27910 GI:15234312
Arabidopsis thaliana (Ath) At5g28390_2 GI:15241785
Arabidopsis thaliana (Ath) At5g42400 GI:15238953
Arabidopsis thaliana (Ath) At5g53430 GI:15238735
Caenorhabditis elegans (Cel) CE01158 GI:17552316 Q18221
Caenorhabditis elegans (Cel) CE27735
(WBGene00004782)		 GI:17552318 Q18221
Caenorhabditis elegans (Cel) CE27736 GI:17552320 Q18221
Drosophila melanogaster (Dme) 7289568 GI:7289568
Homo sapiens (Hsa) Hs22059579 GI:22059579
Saccharomyces cerevisiae (Sce) YHR119w
(S000001161)		 GI:6321911 P38827
Schizosaccharomyces pombe (Spo) SPCC306.04c GI:19075312 Q9Y7R4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC306.04c
GO:0005575 cellular_component C
ND
AthAt5g28390
At3g62500
GO:0005634 nucleus C
IDA
AthAt5g42400
GO:0005737 cytoplasm C
IDA
AthAt5g42400
SpoSPCC306.04c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC306.04c
IPI
SceS000001161
GO:0003674 molecular_function F
ND
AthAt3g62500
GO:0003677 DNA binding F
ISS
AthAt3g61740
At1g05830
At5g53430
GO:0003723 RNA binding F
IDA
SceS000001161
IMP
SceS000001161
ISS
AthAt5g28390
SpoSPCC306.04c
GO:0016279 protein-lysine N-methyltransferase
activity		 F
IGI
SceS000001161
IMP
SceS000001161
GO:0018024 histone-lysine N-methyltransferase
activity		 F
IDA
SpoSPCC306.04c
GO:0042054 histone methyltransferase activity F
ISS
SceS000001161
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001161
IMP
AthAt1g05830
SceS000001161
TAS
SpoSPCC306.04c
GO:0000077 DNA damage checkpoint P
IGI
SpoSPCC306.04c
GO:0000183 chromatin silencing at rDNA P
TAS
SceS000001161
GO:0000723 telomere maintenance P
IMP
SceS000001161
SpoSPCC306.04c
GO:0006338 chromatin remodeling P
ISS
SpoSPCC306.04c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000001161
GO:0006355 regulation of transcription, DNA-dependent P
ISS
AthAt1g05830
At5g53430
At3g61740
GO:0008150 biological_process P
ND
AthAt3g62500
At5g28390
GO:0009294 DNA mediated transformation P
IMP
AthAt5g53430
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000001161
GO:0009909 regulation of flower development P
IMP
AthAt5g42400
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IMP
AthAt5g42400
GO:0010452 histone H3-K36 methylation P
IDA
AthAt5g42400
GO:0016571 histone methylation P
IC
SpoSPCC306.04c
GO:0018022 peptidyl-lysine methylation P
TAS
SpoSPCC306.04c
GO:0018027 peptidyl-lysine dimethylation P
IMP
SceS000001161
IPI
SceS000001161
GO:0030437 ascospore formation P
IMP
SceS000001161
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000001161
GO:0035066 positive regulation of histone
acetylation		 P
IGI
SceS000001161
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IGI
SceS000001161
IMP
SceS000001161
GO:0045449 regulation of transcription P
IMP
AthAt1g05830
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001161
IGI
AthAt5g42400
IMP
AthAt1g05830
SceS000001161
ISS
AthAt5g42400
TAS
SpoSPCC306.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39255

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SET1
(S000001161)		 GI:6321911 P38827
Kluyveromyces lactis (Kla) KLLA0F24134g GI:50312247
Eremothecium gossypii (Ego) AGOS_ABR136W GI:45185366


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0048188 Set1C/COMPASS complex C
IPI
SceS000001161
GO:0003723 RNA binding F
IDA
SceS000001161
IMP
SceS000001161
GO:0016279 protein-lysine N-methyltransferase
activity		 F
IGI
SceS000001161
IMP
SceS000001161
GO:0042054 histone methyltransferase activity F
ISS
SceS000001161
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001161
IMP
SceS000001161
GO:0000183 chromatin silencing at rDNA P
TAS
SceS000001161
GO:0000723 telomere maintenance P
IMP
SceS000001161
GO:0006348 chromatin silencing at telomere P
IMP
SceS000001161
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000001161
GO:0018027 peptidyl-lysine dimethylation P
IMP
SceS000001161
IPI
SceS000001161
GO:0030437 ascospore formation P
IMP
SceS000001161
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000001161
GO:0035066 positive regulation of histone
acetylation		 P
IGI
SceS000001161
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IGI
SceS000001161
IMP
SceS000001161
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001161
IMP
SceS000001161

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_891

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4390 ENSANGP00000021776
Anopheles gambiae (Aga) aga4391 ENSANGP00000021856
Ashbya gossypii (Ago) ago728 ABR136W
Arabidopsis thaliana (Ath) ath26035 At5g42400.1
Caenorhabditis elegans (Cel) cel2779 C26E6.9a
(CE27735;
WBGene00004782)
Caenorhabditis elegans (Cel) cel2780 C26E6.9b
(CE01158)
Caenorhabditis elegans (Cel) cel2781 C26E6.9c
(CE27736)
Candida glabrata (Cgl) cgl4641 CAGL0L12980g
Cryptococcus neoformans (Cne) cne955 163.m06417
Dictyostelium discoideum (Ddi) ddi8893 DDB0188336
Debaryomyces hansenii (Dha) dha5372 DEHA0F22176g
Drosophila melanogaster (Dme) dme19160 CG40351-PA
Drosophila melanogaster (Dme) dme19159 CG40351-PB
Danio rerio (Dre) dre2209 ENSDARP00000010445
Danio rerio (Dre) dre25604 ENSDARP00000012122
Danio rerio (Dre) dre9342 ENSDARP00000017504
Danio rerio (Dre) dre17524 ENSDARP00000023176
Danio rerio (Dre) dre17526 ENSDARP00000029420
Danio rerio (Dre) dre17525 ENSDARP00000038653
Danio rerio (Dre) dre2210 ENSDARP00000045172
Takifugu rubripes (Fru) fru12024 SINFRUP00000160253
Takifugu rubripes (Fru) fru24157 SINFRUP00000161633
Takifugu rubripes (Fru) fru32447 SINFRUP00000165579
Takifugu rubripes (Fru) fru32448 SINFRUP00000165580
Gallus gallus (Gga) gga7223 ENSGALP00000006850
Gallus gallus (Gga) gga7224 ENSGALP00000006883
(RCJMB04_10j6)
Homo sapiens (Hsa) hsa12044 ENSP00000262519
(SETD1A)		 O15047
Homo sapiens (Hsa) hsa8354 ENSP00000267197
(SETD1B)		 Q9UPS6
Homo sapiens (Hsa) hsa8353 ENSP00000347642
Kluyveromyces lactis (Kla) kla5155 KLLA0F24134g
Mus musculus (Mmu) mmu25168 ENSMUSP00000037600
(MGI:2446244)		 Q80V17
Mus musculus (Mmu) mmu25169 ENSMUSP00000047672
(MGI:2446244)		 Q80V17
Mus musculus (Mmu) mmu20903 ENSMUSP00000049571
Neurospora crassa (Ncr) ncr1169 NCU01206.2
Oryza sativa (Osa) osa8641 2643.m00168
Oryza sativa (Osa) osa47771 5650.m00139
Rattus norvegicus (Rno) rno8570 ENSRNOP00000001807
Rattus norvegicus (Rno) rno3048 ENSRNOP00000025773
(GI:309001)		 Q4G026
Rattus norvegicus (Rno) rno8572 ENSRNOP00000030647
Rattus norvegicus (Rno) rno3047 ENSRNOP00000039398
Rattus norvegicus (Rno) rno8571 ENSRNOP00000041176
(RGD:1561386)
Rattus norvegicus (Rno) rno8569 ENSRNOP00000042424
Rattus norvegicus (Rno) rno8573 ENSRNOP00000048737
Saccharomyces cerevisiae (Sce) sce2885 YHR119W
(S000001161)
Schizosaccharomyces pombe (Spo) spo2733 SPCC306.04c Q9Y7R4
Yarrowia lipolytica (Yli) yli1357 YALI0B14883g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC306.04c
GO:0005634 nucleus C
IDA
AthAt5g42400
CelWBGene00004782
ISO
MmuMGI:2446244
GO:0005737 cytoplasm C
IDA
AthAt5g42400
SpoSPCC306.04c
GO:0035097 histone methyltransferase complex C
ISO
MmuMGI:2446244
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC306.04c
IPI
SceS000001161
GO:0003674 molecular_function F
ND
MmuMGI:2446244
GO:0003723 RNA binding F
IDA
SceS000001161
IMP
SceS000001161
ISS
SpoSPCC306.04c
GO:0016279 protein-lysine N-methyltransferase
activity		 F
IGI
SceS000001161
IMP
SceS000001161
GO:0018024 histone-lysine N-methyltransferase
activity		 F
IDA
SpoSPCC306.04c
GO:0042054 histone methyltransferase activity F
ISS
SceS000001161
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
CelWBGene00004782
SceS000001161
IMP
SceS000001161
TAS
SpoSPCC306.04c
GO:0000003 reproduction P
IMP
CelWBGene00004782
GO:0000077 DNA damage checkpoint P
IGI
SpoSPCC306.04c
GO:0000183 chromatin silencing at rDNA P
TAS
SceS000001161
GO:0000723 telomere maintenance P
IMP
SceS000001161
SpoSPCC306.04c
GO:0006338 chromatin remodeling P
ISS
SpoSPCC306.04c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000001161
GO:0006479 protein amino acid methylation P
IMP
CelWBGene00004782
GO:0007126 meiosis P
IMP
CelWBGene00004782
GO:0008150 biological_process P
ND
MmuMGI:2446244
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000001161
GO:0009909 regulation of flower development P
IMP
AthAt5g42400
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IMP
AthAt5g42400
GO:0010452 histone H3-K36 methylation P
IDA
AthAt5g42400
GO:0016246 RNA interference P
IMP
CelWBGene00004782
GO:0016571 histone methylation P
IC
SpoSPCC306.04c
GO:0018022 peptidyl-lysine methylation P
TAS
SpoSPCC306.04c
GO:0018027 peptidyl-lysine dimethylation P
IMP
SceS000001161
IPI
SceS000001161
GO:0030437 ascospore formation P
IMP
SceS000001161
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000001161
GO:0035066 positive regulation of histone
acetylation		 P
IGI
SceS000001161
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004782
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IGI
SceS000001161
IMP
SceS000001161
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00004782
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001161
IGI
AthAt5g42400
IMP
SceS000001161
ISS
AthAt5g42400
TAS
SpoSPCC306.04c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC306.04c
(Q9Y7R4)		 YHR119W
(S000001161)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC306.04c
GO:0005737 cytoplasm C
IDA
SpoSPCC306.04c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC306.04c
IPI
SceS000001161
GO:0003723 RNA binding F
IDA
SceS000001161
IMP
SceS000001161
ISS
SpoSPCC306.04c
GO:0016279 protein-lysine N-methyltransferase
activity		 F
IGI
SceS000001161
IMP
SceS000001161
GO:0018024 histone-lysine N-methyltransferase
activity		 F
IDA
SpoSPCC306.04c
GO:0042054 histone methyltransferase activity F
ISS
SceS000001161
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001161
IMP
SceS000001161
TAS
SpoSPCC306.04c
GO:0000077 DNA damage checkpoint P
IGI
SpoSPCC306.04c
GO:0000183 chromatin silencing at rDNA P
TAS
SceS000001161
GO:0000723 telomere maintenance P
IMP
SceS000001161
SpoSPCC306.04c
GO:0006338 chromatin remodeling P
ISS
SpoSPCC306.04c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000001161
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000001161
GO:0016571 histone methylation P
IC
SpoSPCC306.04c
GO:0018022 peptidyl-lysine methylation P
TAS
SpoSPCC306.04c
GO:0018027 peptidyl-lysine dimethylation P
IMP
SceS000001161
IPI
SceS000001161
GO:0030437 ascospore formation P
IMP
SceS000001161
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000001161
GO:0035066 positive regulation of histone
acetylation		 P
IGI
SceS000001161
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IGI
SceS000001161
IMP
SceS000001161
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001161
IMP
SceS000001161
TAS
SpoSPCC306.04c

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