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Search term: YHR120W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSH1
SGD link S000001162
Alternative ID YHR120W
Description DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis
Synonyms YHR120W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6113

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) msh1
(SPAC13F5.01c)		 GI:19114561 O13921
Saccharomyces cerevisiae (Sce) MSH1
(S000001162)		 GI:6321912
Kluyveromyces lactis (Kla) KLLA0F24156g GI:50312249
Eremothecium gossypii (Ego) AGOS_ABR137W GI:45185367
Magnaporthe grisea (Mgr) MGG_04466 GI:39944968
Neurospora crassa (Ncr) NCU07407.1 GI:32414427


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001162
SpoSPAC13F5.01c
ISS
SpoSPAC13F5.01c
GO:0032300 mismatch repair complex C
ISS
SpoSPAC13F5.01c
GO:0000404 loop DNA binding F
ISS
SpoSPAC13F5.01c
GO:0003684 damaged DNA binding F
ISS
SpoSPAC13F5.01c
GO:0005524 ATP binding F
ISS
SpoSPAC13F5.01c
GO:0008094 DNA-dependent ATPase activity F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0030983 mismatched DNA binding F
ISS
SpoSPAC13F5.01c
GO:0032137 guanine/thymine mispair binding F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0032139 dinucleotide insertion or deletion
binding		 F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000001162
GO:0000710 meiotic mismatch repair P
ISS
SpoSPAC13F5.01c
GO:0006200 ATP catabolic process P
ISS
SpoSPAC13F5.01c
GO:0006281 DNA repair P
IMP
SceS000001162
GO:0006298 mismatch repair P
IMP
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0007005 mitochondrion organization P
IMP
SceS000001162
GO:0043504 mitochondrial DNA repair P
IMP
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0043570 maintenance of DNA repeat elements P
ISS
SpoSPAC13F5.01c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_206

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5483 ENSANGP00000014707
Ashbya gossypii (Ago) ago729 ABR137W
Ashbya gossypii (Ago) ago1910 ADR168C
Ashbya gossypii (Ago) ago4427 AGR116W
Arabidopsis thaliana (Ath) ath14774 At3g24495.1
Arabidopsis thaliana (Ath) ath18083 At4g02070.1
Arabidopsis thaliana (Ath) ath20538 At4g25540.1
Caenorhabditis elegans (Cel) cel19117 Y47G6A.11
(CE28985;
WBGene00003422)
Candida glabrata (Cgl) cgl961 CAGL0E00473g
Candida glabrata (Cgl) cgl1977 CAGL0G08129g
Candida glabrata (Cgl) cgl4642 CAGL0L13002g
Cryptococcus neoformans (Cne) cne3574 176.m02308
Cryptococcus neoformans (Cne) cne3658 176.m02393
Cryptococcus neoformans (Cne) cne5293 179.m00142
Dictyostelium discoideum (Ddi) ddi6179 DDB0204604
Dictyostelium discoideum (Ddi) ddi1617 DDB0217743
Dictyostelium discoideum (Ddi) ddi11575 DDB0229918
Debaryomyces hansenii (Dha) dha1274 DEHA0B13673g
Debaryomyces hansenii (Dha) dha3974 DEHA0E16566g
Debaryomyces hansenii (Dha) dha5373 DEHA0F22198g
Drosophila melanogaster (Dme) dme9581 CG7003-PA
(FBgn0036486)
Danio rerio (Dre) dre28535 ENSDARP00000017721
(msh6)		 Q803S7
Danio rerio (Dre) dre16038 ENSDARP00000042277
Danio rerio (Dre) dre16039 ENSDARP00000042980
Escherichia coli (Eco) eco2641 16130640
Encephalitozoon cuniculi (Ecu) ecu596 19074680
Takifugu rubripes (Fru) fru22790 SINFRUP00000145736
Takifugu rubripes (Fru) fru31929 SINFRUP00000164085
Takifugu rubripes (Fru) fru31930 SINFRUP00000164089
Takifugu rubripes (Fru) fru22789 SINFRUP00000166199
Takifugu rubripes (Fru) fru31931 SINFRUP00000171309
Gallus gallus (Gga) gga14474 ENSGALP00000014551
(MSH6)
Gallus gallus (Gga) gga14475 ENSGALP00000014552
Gallus gallus (Gga) gga27997 ENSGALP00000025089
Gallus gallus (Gga) gga27998 ENSGALP00000025090
Homo sapiens (Hsa) hsa17789 ENSP00000234420
(MSH6)		 P52701-1
Homo sapiens (Hsa) hsa25455 ENSP00000265081
(MSH3)		 P20585
Kluyveromyces lactis (Kla) kla1991 KLLA0C17732g
Kluyveromyces lactis (Kla) kla2027 KLLA0C18590g
Kluyveromyces lactis (Kla) kla5156 KLLA0F24156g
Mus musculus (Mmu) mmu12216 ENSMUSP00000005503
(MGI:1343961)		 Q61061
Mus musculus (Mmu) mmu7353 ENSMUSP00000022220
(MGI:109519)		 B2RWY6
Neurospora crassa (Ncr) ncr7209 NCU07407.2
Neurospora crassa (Ncr) ncr7907 NCU08115.2
Neurospora crassa (Ncr) ncr7927 NCU08135.2
Oryza sativa (Osa) osa10799 2756.m00107
Oryza sativa (Osa) osa10885 2758.m00119
Oryza sativa (Osa) osa47200 5773.m00098
Oryza sativa (Osa) osa52886 5946.m00119
Oryza sativa (Osa) osa53230 5956.m00244
Oryza sativa (Osa) osa81378 8123.m00150
Plasmodium falciparum (Pfa) pfa3505 PFE0270c
Rattus norvegicus (Rno) rno15338 ENSRNOP00000018449
(RGD:1563954)
Rattus norvegicus (Rno) rno24696 ENSRNOP00000021923
Saccharomyces cerevisiae (Sce) sce749 YCR092C
(S000000688)
Saccharomyces cerevisiae (Sce) sce1132 YDR097C
(S000002504)
Saccharomyces cerevisiae (Sce) sce2886 YHR120W
(S000001162)
Schizosaccharomyces pombe (Spo) spo551 SPAC13F5.01c O13921
Schizosaccharomyces pombe (Spo) spo544 SPAC8F11.03 P26359
Schizosaccharomyces pombe (Spo) spo3713 SPCC285.16c O74502
Yarrowia lipolytica (Yli) yli321 YALI0A09724g
Yarrowia lipolytica (Yli) yli1156 YALI0B10197g
Yarrowia lipolytica (Yli) yli6451 YALI0F26499g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
ISS
SpoSPAC8F11.03
SPCC285.16c
GO:0000790 nuclear chromatin C
IDA
MmuMGI:1343961
GO:0005634 nucleus C
IDA
SceS000000688
S000002504
SpoSPCC285.16c
SPAC8F11.03
GO:0005737 cytoplasm C
IDA
SceS000000688
GO:0005739 mitochondrion C
IDA
SceS000001162
SpoSPAC13F5.01c
ISS
SpoSPAC13F5.01c
GO:0005829 cytosol C
IDA
SpoSPCC285.16c
GO:0032300 mismatch repair complex C
ISS
SpoSPAC13F5.01c
GO:0032301 MutSalpha complex C
IDA
MmuMGI:1343961
IPI
SceS000002504
ISS
CelWBGene00003422
SpoSPCC285.16c
GO:0032302 MutSbeta complex C
IPI
SceS000000688
ISS
SpoSPAC8F11.03
GO:0000400 four-way junction DNA binding F
IDA
SceS000002504
ISS
SpoSPCC285.16c
RCA
SceS000000688
GO:0000403 Y-form DNA binding F
IDA
SceS000000688
ISS
SpoSPAC8F11.03
RCA
SceS000002504
GO:0000404 loop DNA binding F
IDA
SceS000000688
ISS
SpoSPAC13F5.01c
SPAC8F11.03
RCA
SceS000002504
GO:0000406 double-strand/single-strand DNA junction
binding		 F
IDA
SceS000000688
ISS
SpoSPAC8F11.03
GO:0001882 nucleoside binding F
RCA
SceS000000688
GO:0001883 purine nucleoside binding F
RCA
SceS000000688
GO:0003677 DNA binding F
IGI
MmuMGI:1343961
MGI:109519
IMP
MmuMGI:1343961
ISS
CelWBGene00003422
GO:0003682 chromatin binding F
IDA
MmuMGI:1343961
GO:0003684 damaged DNA binding F
IDA
AthAt4g02070
At4g25540
IGI
MmuMGI:1343961
MGI:109519
IMP
MmuMGI:1343961
ISS
AthAt3g24495
SpoSPAC13F5.01c
SPAC8F11.03
SPCC285.16c
GO:0005515 protein binding F
IPI
AthAt4g25540
GO:0005524 ATP binding F
IDA
SceS000002504
ISS
AthAt3g24495
SpoSPAC13F5.01c
SPAC8F11.03
SPCC285.16c
RCA
SceS000000688
GO:0008094 DNA-dependent ATPase activity F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
SPAC8F11.03
SPCC285.16c
GO:0016887 ATPase activity F
IDA
SceS000002504
RCA
SceS000000688
GO:0019237 centromeric DNA binding F
IDA
MmuMGI:109519
GO:0030554 adenyl nucleotide binding F
RCA
SceS000000688
GO:0030983 mismatched DNA binding F
IDA
AthAt4g25540
SceS000000688
ISS
SpoSPAC13F5.01c
GO:0032135 DNA insertion or deletion binding F
IDA
SceS000000688
ISS
SpoSPAC8F11.03
GO:0032137 guanine/thymine mispair binding F
IDA
MmuMGI:1343961
MGI:1343961
SceS000001162
S000002504
ISS
SpoSPAC13F5.01c
SPCC285.16c
RCA
SceS000000688
GO:0032138 single base insertion or deletion
binding		 F
IDA
SceS000002504
IMP
SceS000002504
ISS
SpoSPCC285.16c
GO:0032139 dinucleotide insertion or deletion
binding		 F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0032559 adenyl ribonucleotide binding F
RCA
SceS000000688
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000001162
GO:0000710 meiotic mismatch repair P
IMP
DmeFBgn0036486
SceS000002504
S000000688
ISS
SpoSPAC13F5.01c
SPAC8F11.03
SPCC285.16c
GO:0000735 removal of nonhomologous ends P
IGI
SceS000000688
IMP
SceS000000688
ISS
SpoSPAC8F11.03
TAS
SceS000000688
GO:0000737 DNA catabolic process, endonucleolytic P
RCA
SceS000002504
GO:0003006 reproductive developmental process P
RCA
SceS000002504
GO:0006200 ATP catabolic process P
ISS
SpoSPAC13F5.01c
GO:0006260 DNA replication P
RCA
SceS000002504
GO:0006281 DNA repair P
IMP
SceS000001162
ISS
DmeFBgn0036486
RCA
SceS000002504
GO:0006298 mismatch repair P
IDA
SceS000002504
IGI
MmuMGI:109519
MGI:1343961
IMP
CelWBGene00003422
MmuMGI:109519
MGI:1343961
SceS000001162
S000000688
S000002504
SpoSPCC285.16c
ISS
AthAt3g24495
At4g25540
At4g02070
SpoSPAC13F5.01c
GO:0006301 postreplication repair P
NAS
DmeFBgn0036486
GO:0006308 DNA catabolic process P
RCA
SceS000002504
GO:0006310 DNA recombination P
IMP
SceS000000688
RCA
SceS000002504
GO:0006312 mitotic recombination P
IMP
SceS000000688
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00003422
RCA
SceS000002504
GO:0007005 mitochondrion organization P
IMP
SceS000001162
GO:0007131 reciprocal meiotic recombination P
IMP
SpoSPAC8F11.03
ISS
SpoSPCC285.16c
GO:0007530 sex determination P
RCA
SceS000002504
GO:0007531 mating type determination P
RCA
SceS000002504
GO:0007533 mating type switching P
RCA
SceS000002504
GO:0007534 gene conversion at mating-type
locus		 P
IMP
SpoSPAC8F11.03
GO:0008340 determination of adult lifespan P
IMP
MmuMGI:1343961
GO:0008629 induction of apoptosis by intracellular
signals		 P
IMP
MmuMGI:1343961
GO:0008630 DNA damage response, signal transduction resulting
in induction of apoptosis		 P
IMP
MmuMGI:1343961
ISS
SpoSPCC285.16c
GO:0009411 response to UV P
IMP
MmuMGI:1343961
ISS
SpoSPCC285.16c
GO:0016446 somatic hypermutation of immunoglobulin
genes		 P
IMP
MmuMGI:1343961
GO:0016447 somatic recombination of immunoglobulin gene
segments		 P
IMP
MmuMGI:1343961
MGI:109519
GO:0043504 mitochondrial DNA repair P
IMP
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0043570 maintenance of DNA repeat elements P
IMP
CelWBGene00003422
SpoSPCC285.16c
SPAC8F11.03
ISS
SpoSPAC13F5.01c
GO:0045190 isotype switching P
IMP
MmuMGI:1343961
GO:0045910 negative regulation of DNA recombination P
IMP
MmuMGI:1343961
ISS
SpoSPCC285.16c
GO:0051321 meiotic cell cycle P
RCA
SceS000002504

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC13F5.01c
(O13921)		 YHR120W
(S000001162)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001162
SpoSPAC13F5.01c
ISS
SpoSPAC13F5.01c
GO:0032300 mismatch repair complex C
ISS
SpoSPAC13F5.01c
GO:0000404 loop DNA binding F
ISS
SpoSPAC13F5.01c
GO:0003684 damaged DNA binding F
ISS
SpoSPAC13F5.01c
GO:0005524 ATP binding F
ISS
SpoSPAC13F5.01c
GO:0008094 DNA-dependent ATPase activity F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0030983 mismatched DNA binding F
ISS
SpoSPAC13F5.01c
GO:0032137 guanine/thymine mispair binding F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0032139 dinucleotide insertion or deletion
binding		 F
IDA
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000001162
GO:0000710 meiotic mismatch repair P
ISS
SpoSPAC13F5.01c
GO:0006200 ATP catabolic process P
ISS
SpoSPAC13F5.01c
GO:0006281 DNA repair P
IMP
SceS000001162
GO:0006298 mismatch repair P
IMP
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0007005 mitochondrion organization P
IMP
SceS000001162
GO:0043504 mitochondrial DNA repair P
IMP
SceS000001162
ISS
SpoSPAC13F5.01c
GO:0043570 maintenance of DNA repeat elements P
ISS
SpoSPAC13F5.01c

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