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Search term: YHR171W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ATG7
SGD link S000001214
Alternative ID YHR171W
Description Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation
Synonyms YHR171W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2337 ACDHYP-

KOGs classification KOGs description
METABOLISM Ubiquitin activating E1 enzyme-like protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g45900 GI:9758937
Caenorhabditis elegans (Cel) CE18887
(WBGene00010882)		 GI:17541546 Q21591
Drosophila melanogaster (Dme) 7302584
(FBgn0034366)		 GI:19922550 A1ZBA9
Drosophila melanogaster (Dme) 7302585 GI:7302585 A1ZBA9
Homo sapiens (Hsa) Hs5453668
(ATG7)		 GI:5453668 O95352
Saccharomyces cerevisiae (Sce) YHR171w
(S000001214)		 GI:6321965 P38862
Schizosaccharomyces pombe (Spo) SPBC6B1.05c GI:19112876 O43069


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000407 pre-autophagosomal structure C
IDA
SceS000001214
GO:0005575 cellular_component C
ND
AthAt5g45900
GO:0005634 nucleus C
IDA
SpoSPBC6B1.05c
GO:0005737 cytoplasm C
IDA
HsaATG7
GO:0005739 mitochondrion C
IDA
SceS000001214
GO:0005829 cytosol C
IDA
SceS000001214
SpoSPBC6B1.05c
GO:0016020 membrane C
IDA
SceS000001214
GO:0004839 ubiquitin activating enzyme activity F
TAS
HsaATG7
GO:0005515 protein binding F
IPI
HsaATG7
GO:0019778 APG12 activating enzyme activity F
IMP
SceS000001214
IPI
SceS000001214
ISS
HsaATG7
GO:0019779 APG8 activating enzyme activity F
IMP
SceS000001214
IPI
SceS000001214
ISS
AthAt5g45900
GO:0019787 small conjugating protein ligase
activity		 F
ISS
SpoSPBC6B1.05c
GO:0042803 protein homodimerization activity F
IDA
HsaATG7
GO:0000003 reproduction P
IMP
CelWBGene00010882
GO:0000422 mitochondrion degradation P
IMP
SceS000001214
GO:0006464 protein modification process P
TAS
HsaATG7
GO:0006497 protein amino acid lipidation P
IDA
HsaATG7
ISS
AthAt5g45900
GO:0006501 C-terminal protein lipidation P
IDA
SceS000001214
IMP
SceS000001214
GO:0006914 autophagy P
IGI
CelWBGene00010882
IMP
DmeFBgn0034366
SpoSPBC6B1.05c
ISS
AthAt5g45900
RCA
SceS000001214
GO:0006944 cellular membrane fusion P
TAS
HsaATG7
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC6B1.05c
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00010882
IMP
CelWBGene00010882
DmeFBgn0034366
GO:0010150 leaf senescence P
IMP
AthAt5g45900
TAS
AthAt5g45900
GO:0016236 macroautophagy P
IC
SpoSPBC6B1.05c
IMP
DmeFBgn0034366
SceS000001214
GO:0030163 protein catabolic process P
IMP
CelWBGene00010882
GO:0031401 positive regulation of protein modification
process		 P
IDA
HsaATG7
GO:0032258 CVT pathway P
IMP
SceS000001214
ISS
SpoSPBC6B1.05c
GO:0032446 protein modification by small protein
conjugation		 P
IMP
SceS000001214
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000001214
GO:0035096 larval midgut cell programmed cell
death		 P
IMP
DmeFBgn0034366
GO:0040024 dauer larval development P
IGI
CelWBGene00010882
GO:0050688 regulation of defense response to
virus		 P
IMP
DmeFBgn0034366

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4662

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATG7 GI:5453668 O95352
Canis familiaris (Cfa) ATG7 GI:73984600
Mus musculus (Mmu) Atg7
(MGI:1921494)		 GI:22550098 Q3TAB9
Rattus norvegicus (Rno) Atg7
(RGD:1304817)		 GI:58865764
Gallus gallus (Gga) ATG7 GI:71895443
Drosophila melanogaster (Dme) Atg7
(FBgn0034366)		 GI:19922550 A1ZBA9
Anopheles gambiae (Aga) AgaP_AGAP010303 GI:158298090
Caenorhabditis elegans (Cel) atg-7
(CE18887;
WBGene00010882)		 GI:17541546 Q21591
Schizosaccharomyces pombe (Spo) SPBC6B1.05c GI:19112876 O43069
Saccharomyces cerevisiae (Sce) ATG7
(S000001214)		 GI:6321965 P38862
Kluyveromyces lactis (Kla) KLLA0A05137g GI:50302581
Eremothecium gossypii (Ego) AGOS_AER298C GI:45190901
Magnaporthe grisea (Mgr) MGG_07297 GI:145612667
Neurospora crassa (Ncr) NCU06672.1 GI:32412956
Arabidopsis thaliana (Ath) APG7 GI:18422607
Oryza sativa (Osa) Os01g0614900 GI:115438558


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000407 pre-autophagosomal structure C
IDA
SceS000001214
GO:0005575 cellular_component C
ND
AthAPG7
GO:0005634 nucleus C
IDA
SpoSPBC6B1.05c
GO:0005737 cytoplasm C
IDA
HsaATG7
GO:0005739 mitochondrion C
IDA
SceS000001214
GO:0005829 cytosol C
IDA
SceS000001214
SpoSPBC6B1.05c
GO:0016020 membrane C
IDA
SceS000001214
GO:0004839 ubiquitin activating enzyme activity F
IDA
MmuMGI:1921494
TAS
HsaATG7
GO:0005515 protein binding F
IPI
HsaATG7
MmuMGI:1921494
GO:0019778 APG12 activating enzyme activity F
IMP
SceS000001214
IPI
SceS000001214
ISS
HsaATG7
GO:0019779 APG8 activating enzyme activity F
IMP
SceS000001214
IPI
SceS000001214
ISS
AthAPG7
GO:0019787 small conjugating protein ligase
activity		 F
ISS
SpoSPBC6B1.05c
GO:0042803 protein homodimerization activity F
IDA
HsaATG7
GO:0000003 reproduction P
IMP
CelWBGene00010882
GO:0000422 mitochondrion degradation P
IMP
SceS000001214
GO:0001889 liver development P
IMP
MmuMGI:1921494
GO:0006464 protein modification process P
TAS
HsaATG7
GO:0006497 protein amino acid lipidation P
IDA
HsaATG7
ISO
MmuMGI:1921494
ISS
AthAPG7
GO:0006501 C-terminal protein lipidation P
IDA
SceS000001214
IMP
SceS000001214
GO:0006520 cellular amino acid metabolic process P
IMP
MmuMGI:1921494
GO:0006914 autophagy P
IGI
CelWBGene00010882
IMP
DmeFBgn0034366
MmuMGI:1921494
SpoSPBC6B1.05c
ISS
AthAPG7
RCA
SceS000001214
GO:0006944 cellular membrane fusion P
TAS
HsaATG7
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC6B1.05c
GO:0006996 organelle organization P
IMP
MmuMGI:1921494
GO:0007628 adult walking behavior P
IMP
MmuMGI:1921494
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00010882
IMP
CelWBGene00010882
DmeFBgn0034366
GO:0009791 post-embryonic development P
IMP
MmuMGI:1921494
GO:0010150 leaf senescence P
IMP
AthAPG7
TAS
AthAPG7
GO:0016044 cellular membrane organization P
IMP
MmuMGI:1921494
GO:0016236 macroautophagy P
IC
SpoSPBC6B1.05c
IMP
DmeFBgn0034366
SceS000001214
GO:0021680 cerebellar Purkinje cell layer
development		 P
IMP
MmuMGI:1921494
GO:0021860 pyramidal neuron development P
IMP
MmuMGI:1921494
GO:0021987 cerebral cortex development P
IMP
MmuMGI:1921494
GO:0030163 protein catabolic process P
IMP
CelWBGene00010882
MmuMGI:1921494
GO:0031175 neuron projection development P
IMP
MmuMGI:1921494
GO:0031396 regulation of protein ubiquitination P
IMP
MmuMGI:1921494
GO:0031401 positive regulation of protein modification
process		 P
IDA
HsaATG7
MmuMGI:1921494
ISO
MmuMGI:1921494
GO:0032258 CVT pathway P
IMP
SceS000001214
ISS
SpoSPBC6B1.05c
GO:0032446 protein modification by small protein
conjugation		 P
IMP
MmuMGI:1921494
SceS000001214
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000001214
GO:0035096 larval midgut cell programmed cell
death		 P
IMP
DmeFBgn0034366
GO:0040024 dauer larval development P
IGI
CelWBGene00010882
GO:0042594 response to starvation P
IMP
MmuMGI:1921494
GO:0043066 negative regulation of apoptosis P
IMP
MmuMGI:1921494
GO:0050688 regulation of defense response to
virus		 P
IMP
DmeFBgn0034366
GO:0050877 neurological system process P
IMP
MmuMGI:1921494
GO:0055013 cardiac muscle cell development P
IMP
MmuMGI:1921494

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1944

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga13925 ENSANGP00000001364
Anopheles gambiae (Aga) aga13926 ENSANGP00000023120
Ashbya gossypii (Ago) ago2800 AER298C
Arabidopsis thaliana (Ath) ath26446 At5g45900.1
Caenorhabditis elegans (Cel) cel13097 M7.5
(CE18887;
WBGene00010882)
Candida glabrata (Cgl) cgl2628 CAGL0I02420g
Cryptococcus neoformans (Cne) cne174 162.m02616
Dictyostelium discoideum (Ddi) ddi11885 DDB0214819
Debaryomyces hansenii (Dha) dha6802 DEHA0G24838g
Drosophila melanogaster (Dme) dme5897 CG5489-PA
(FBgn0034366)
Drosophila melanogaster (Dme) dme5898 CG5489-PB
(FBgn0034366)
Danio rerio (Dre) dre22299 ENSDARP00000018189
Takifugu rubripes (Fru) fru27133 SINFRUP00000164082
Takifugu rubripes (Fru) fru27134 SINFRUP00000169106
Takifugu rubripes (Fru) fru27132 SINFRUP00000177221
Gallus gallus (Gga) gga5094 ENSGALP00000007877
(ATG7)
Homo sapiens (Hsa) hsa22088 ENSP00000346437
(ATG7)		 O95352-1
Homo sapiens (Hsa) hsa22089 ENSP00000347042
(ATG7)		 O95352-2
Kluyveromyces lactis (Kla) kla223 KLLA0A05137g
Mus musculus (Mmu) mmu22520 ENSMUSP00000032457
(MGI:1921494)		 Q9D906
Neurospora crassa (Ncr) ncr6488 NCU06672.2
Oryza sativa (Osa) osa9301 2701.m00084
Plasmodium falciparum (Pfa) pfa722 PF11_0271
Rattus norvegicus (Rno) rno22012 ENSRNOP00000010265
(RGD:1304817)
Saccharomyces cerevisiae (Sce) sce2943 YHR171W
(S000001214)
Schizosaccharomyces pombe (Spo) spo3314 SPBC6B1.05c O43069
Yarrowia lipolytica (Yli) yli2519 YALI0C20119g