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Search term: YHR174W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ENO2
SGD link S000001217
Alternative ID YHR174W
Description Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose
Synonyms YHR174W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2670 ACDHYPE

KOGs classification KOGs description
METABOLISM Enolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g74030 GI:15221107
Arabidopsis thaliana (Ath) At2g29560 GI:15227561
Arabidopsis thaliana (Ath) At2g36530 GI:15227987
Caenorhabditis elegans (Cel) CE03684
(WBGene00011884)		 GI:17536383 Q27527
Drosophila melanogaster (Dme) 7296048 GI:17137654
Homo sapiens (Hsa) Hs18575411 GI:18575411
Homo sapiens (Hsa) Hs20478436 GI:20478436
Homo sapiens (Hsa) Hs22064391 GI:22064391
Homo sapiens (Hsa) Hs4503571
(ENO1)		 GI:4503571 P06733
Homo sapiens (Hsa) Hs4503573 GI:4503573
Homo sapiens (Hsa) Hs5803011
(ENO2)		 GI:5803011 P09104
Homo sapiens (Hsa) Hs7657062 GI:7657062
Saccharomyces cerevisiae (Sce) YGR254w
(S000003486)		 GI:6321693 P00924
Saccharomyces cerevisiae (Sce) YHR174w
(S000001217)		 GI:6321968 P00925
Saccharomyces cerevisiae (Sce) YMR323w
(S000004942)		 GI:6323985 P42222
Saccharomyces cerevisiae (Sce) YOR393w
(S000005920)		 GI:6324969 Q12007
Saccharomyces cerevisiae (Sce) YPL281c
(S000006202)		 GI:6324974 Q12007
Schizosaccharomyces pombe (Spo) SPBC1815.01 GI:19112695 P40370
Encephalitozoon cuniculi (Ecu) ECU10g1690 GI:19074779 Q8SUA4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000015 phosphopyruvate hydratase complex C
IDA
SceS000001217
S000003486
GO:0000324 fungal-type vacuole C
IDA
SceS000003486
S000001217
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000003486
S000001217
GO:0005575 cellular_component C
ND
SceS000006202
S000005920
GO:0005625 soluble fraction C
IDA
SceS000001217
GO:0005634 nucleus C
IC
HsaENO1
IDA
AthAt2g29560
At2g36530
SpoSPBC1815.01
GO:0005737 cytoplasm C
IDA
AthAt2g29560
At2g36530
HsaENO1
SceS000003486
S000004942
GO:0005739 mitochondrion C
IDA
AthAt2g36530
SceS000001217
S000003486
GO:0005740 mitochondrial envelope C
IDA
AthAt2g36530
GO:0005829 cytosol C
IDA
SpoSPBC1815.01
GO:0005886 plasma membrane C
IDA
AthAt2g36530
GO:0009507 chloroplast C
IDA
AthAt1g74030
At2g36530
GO:0009898 internal side of plasma membrane C
IDA
SceS000001217
GO:0016020 membrane C
IDA
AthAt2g36530
GO:0048046 apoplast C
IDA
AthAt2g36530
GO:0003700 transcription factor activity F
TAS
HsaENO1
GO:0003714 transcription corepressor activity F
TAS
HsaENO1
GO:0004634 phosphopyruvate hydratase activity F
IDA
AthAt1g74030
At2g36530
IMP
SceS000001217
S000003486
ISA
SceS000004942
S000006202
S000005920
ISS
AthAt2g29560
At2g36530
At1g74030
SceS000004942
SpoSPBC1815.01
GO:0005507 copper ion binding F
IDA
AthAt2g36530
GO:0005515 protein binding F
IPI
HsaENO1
GO:0016564 transcription repressor activity F
IDA
HsaENO1
GO:0000003 reproduction P
IMP
CelWBGene00011884
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
TAS
HsaENO1
GO:0002119 nematode larval development P
IMP
CelWBGene00011884
GO:0006066 alcohol metabolic process P
RCA
SceS000001217
S000003486
GO:0006082 organic acid metabolic process P
RCA
SceS000001217
S000003486
GO:0006094 gluconeogenesis P
IEP
SceS000001217
S000003486
GO:0006096 glycolysis P
IMP
SceS000001217
S000003486
ISS
SpoSPBC1815.01
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00011884
GO:0008150 biological_process P
ND
SceS000006202
S000004942
S000005920
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00011884
GO:0009409 response to cold P
IMP
AthAt2g36530
GO:0009416 response to light stimulus P
IMP
AthAt2g36530
GO:0009615 response to virus P
IEP
HsaENO1
GO:0009651 response to salt stress P
IEP
AthAt2g36530
GO:0009737 response to abscisic acid stimulus P
IEP
AthAt2g36530
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011884
GO:0010090 trichome morphogenesis P
IMP
AthAt1g74030
GO:0030308 negative regulation of cell growth P
IDA
HsaENO1
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000001217
S000003486
IMP
SceS000003486
S000001217
GO:0040007 growth P
IMP
CelWBGene00011884
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011884
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00011884
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00011884
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003486
S000001217
GO:0045892 negative regulation of transcription,
DNA-dependent		 P
IDA
HsaENO1
GO:0046686 response to cadmium ion P
IEP
AthAt2g36530

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68183

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ENO1 GI:4503571 P06733
Pan troglodytes (Ptr) ENO1 GI:114552694
Canis familiaris (Cfa) ENO1 GI:73956730
Mus musculus (Mmu) Eno1
(MGI:95393)		 GI:12963491 Q6PHC1
Mus musculus (Mmu) Gm5506 GI:70794816
Rattus norvegicus (Rno) LOC688509 GI:109468300
Rattus norvegicus (Rno) Eno1
(RGD:2553)		 GI:6978809 33907
Gallus gallus (Gga) RCJMB04_24e12 GI:46048768
Drosophila melanogaster (Dme) Eno
(FBgn0000579)		 GI:24580914
Anopheles gambiae (Aga) AgaP_AGAP007827 GI:58390364
Caenorhabditis elegans (Cel) enol-1
(CE03684;
WBGene00011884)		 GI:71995829
Schizosaccharomyces pombe (Spo) eno102
(SPBPB21E7.01c)		 GI:68006354 Q8NKC2
Schizosaccharomyces pombe (Spo) eno1
(SPBC1815.01)		 GI:19112695 P40370
Saccharomyces cerevisiae (Sce) ENO1
(S000003486)		 GI:6321693 P00924
Saccharomyces cerevisiae (Sce) ENO2
(S000001217)		 GI:6321968 P00925
Kluyveromyces lactis (Kla) KLLA0A09185g GI:50302929
Eremothecium gossypii (Ego) AGOS_AER294C GI:45190897
Magnaporthe grisea (Mgr) MGG_10607 GI:145616440
Neurospora crassa (Ncr) NCU10042.1 GI:32405096
Arabidopsis thaliana (Ath) AT1G74030 GI:15221107
Oryza sativa (Osa) Os09g0375000 GI:115478881


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000015 phosphopyruvate hydratase complex C
IDA
SceS000001217
S000003486
GO:0000324 fungal-type vacuole C
IDA
SceS000003486
S000001217
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000003486
S000001217
GO:0005625 soluble fraction C
IDA
SceS000001217
ISO
MmuMGI:95393
GO:0005626 insoluble fraction C
ISO
MmuMGI:95393
GO:0005634 nucleus C
IC
HsaENO1
IDA
SpoSPBC1815.01
GO:0005737 cytoplasm C
IDA
HsaENO1
SceS000003486
GO:0005739 mitochondrion C
IDA
SceS000001217
S000003486
GO:0005811 lipid particle C
IDA
DmeFBgn0000579
GO:0005829 cytosol C
IDA
SpoSPBC1815.01
GO:0009507 chloroplast C
IDA
AthAt1g74030
GO:0009898 internal side of plasma membrane C
IDA
SceS000001217
GO:0019717 synaptosome C
ISO
MmuMGI:95393
GO:0003700 transcription factor activity F
TAS
HsaENO1
GO:0003714 transcription corepressor activity F
TAS
HsaENO1
GO:0004634 phosphopyruvate hydratase activity F
IDA
AthAt1g74030
MmuMGI:95393
IMP
SceS000001217
S000003486
ISO
MmuMGI:95393
ISS
AthAt1g74030
DmeFBgn0000579
SpoSPBC1815.01
SPBPB21E7.01c
GO:0005515 protein binding F
IPI
HsaENO1
MmuMGI:95393
GO:0016564 transcription repressor activity F
IDA
HsaENO1
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:95393
GO:0046982 protein heterodimerization activity F
ISO
MmuMGI:95393
GO:0000003 reproduction P
IMP
CelWBGene00011884
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
TAS
HsaENO1
GO:0001701 in utero embryonic development P
IMP
MmuMGI:95393
GO:0002119 nematode larval development P
IMP
CelWBGene00011884
GO:0006066 alcohol metabolic process P
RCA
SceS000001217
S000003486
GO:0006082 organic acid metabolic process P
RCA
SceS000001217
S000003486
GO:0006094 gluconeogenesis P
IEP
SceS000001217
S000003486
GO:0006096 glycolysis P
IMP
SceS000001217
S000003486
ISS
SpoSPBC1815.01
SPBPB21E7.01c
NAS
DmeFBgn0000579
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00011884
GO:0008152 metabolic process P
IDA
MmuMGI:95393
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00011884
GO:0009615 response to virus P
IEP
HsaENO1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011884
GO:0010090 trichome morphogenesis P
IMP
AthAt1g74030
GO:0030308 negative regulation of cell growth P
IDA
HsaENO1
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000001217
S000003486
IMP
SceS000003486
S000001217
GO:0040007 growth P
IMP
CelWBGene00011884
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011884
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00011884
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00011884
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003486
S000001217
GO:0045892 negative regulation of transcription,
DNA-dependent		 P
IDA
HsaENO1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_149

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9746 ENSANGP00000018531
Anopheles gambiae (Aga) aga9747 ENSANGP00000023637
Ashbya gossypii (Ago) ago2796 AER294C
Arabidopsis thaliana (Ath) ath6709 At1g74030.1
Arabidopsis thaliana (Ath) ath10724 At2g36530.1
Caenorhabditis elegans (Cel) cel15863 T21B10.2a
(CE03684;
WBGene00011884)
Caenorhabditis elegans (Cel) cel15865 T21B10.2c
(CE36954)
Candida glabrata (Cgl) cgl1586 CAGL0F08261g
Candida glabrata (Cgl) cgl2631 CAGL0I02486g
Cryptococcus neoformans (Cne) cne2886 167.m03159
Cryptococcus neoformans (Cne) cne3300 167.m03658
Cryptococcus neoformans (Cne) cne5171 179.m00017
Dictyostelium discoideum (Ddi) ddi12752 DDB0231355
Dictyostelium discoideum (Ddi) ddi11572 DDB0231356
Debaryomyces hansenii (Dha) dha2420 DEHA0D02805g
Debaryomyces hansenii (Dha) dha6366 DEHA0G14927g
Drosophila melanogaster (Dme) dme277 CG17654-PA
(FBgn0000579)
Drosophila melanogaster (Dme) dme273 CG17654-PB
(FBgn0000579)
Drosophila melanogaster (Dme) dme275 CG17654-PC
(FBgn0000579)
Drosophila melanogaster (Dme) dme276 CG17654-PD
(FBgn0000579)
Drosophila melanogaster (Dme) dme274 CG17654-PE
(FBgn0000579)
Danio rerio (Dre) dre20633 ENSDARP00000002923
(zgc:73056)		 Q6PC89
Escherichia coli (Eco) eco2686 16130686
Encephalitozoon cuniculi (Ecu) ecu695 19074779
Takifugu rubripes (Fru) fru815 SINFRUP00000131536
Takifugu rubripes (Fru) fru18125 SINFRUP00000136860
Takifugu rubripes (Fru) fru18127 SINFRUP00000136862
Takifugu rubripes (Fru) fru18126 SINFRUP00000136866
Takifugu rubripes (Fru) fru14835 SINFRUP00000150208
Takifugu rubripes (Fru) fru14836 SINFRUP00000168307
Takifugu rubripes (Fru) fru14838 SINFRUP00000176431
Gallus gallus (Gga) gga1576 ENSGALP00000023398
(ENO2)		 O57391
Homo sapiens (Hsa) hsa6995 ENSP00000229277
(ENO2)		 P09104
Homo sapiens (Hsa) hsa216 ENSP00000234590
(ENO1)		 P06733-1
Homo sapiens (Hsa) hsa12869 ENSP00000324105
(ENO3)		 P13929-1
Homo sapiens (Hsa) hsa215 ENSP00000351745
Kluyveromyces lactis (Kla) kla399 KLLA0A09185g
Mus musculus (Mmu) mmu22717 ENSMUSP00000004378
(MGI:95394)		 P17183
Mus musculus (Mmu) mmu4098 ENSMUSP00000065681
Mus musculus (Mmu) mmu4097 ENSMUSP00000072620
(MGI:95395)		 P21550
Mus musculus (Mmu) mmu12686 ENSMUSP00000075513
(MGI:95393)		 P17182
Mus musculus (Mmu) mmu14861 ENSMUSP00000079045
(MGI:95393)		 Q6PHC1
Mus musculus (Mmu) mmu19470 ENSMUSP00000079727
(MGI:95393)		 P17182
Neurospora crassa (Ncr) ncr1820 NCU01870.2
Neurospora crassa (Ncr) ncr9777 NCU10042.2
Oryza sativa (Osa) osa877 1912.m00170
Oryza sativa (Osa) osa19918 3385.m00147
Oryza sativa (Osa) osa39994 5006.m00092
Oryza sativa (Osa) osa38133 5035.m00138
Oryza sativa (Osa) osa47840 5795.m00165
Oryza sativa (Osa) osa47938 5797.m00176
Oryza sativa (Osa) osa51769 5886.m00161
Oryza sativa (Osa) osa51813 5886.m00375
Oryza sativa (Osa) osa57221 6405.m00145
Plasmodium falciparum (Pfa) pfa376 PF10_0155
Rattus norvegicus (Rno) rno22203 ENSRNOP00000005601
(RGD:2554)		 P07323
Rattus norvegicus (Rno) rno5422 ENSRNOP00000005612
(RGD:2555)		 P15429
Rattus norvegicus (Rno) rno24465 ENSRNOP00000024106
(RGD:2553)		 P04764
Rattus norvegicus (Rno) rno22063 ENSRNOP00000038380
Saccharomyces cerevisiae (Sce) sce2636 YGR254W
(S000003486)
Saccharomyces cerevisiae (Sce) sce2946 YHR174W
(S000001217)
Saccharomyces cerevisiae (Sce) sce5105 YMR323W
(S000004942)
Saccharomyces cerevisiae (Sce) sce6150 YOR393W
(S000005920)
Saccharomyces cerevisiae (Sce) sce6448 YPL281C
(S000006202)
Schizosaccharomyces pombe (Spo) spo4754 SPBC1815.01 P40370
Schizosaccharomyces pombe (Spo) spo258 SPBPB21E7.01c Q8NKC2
Yarrowia lipolytica (Yli) yli6047 YALI0F16819g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000015 phosphopyruvate hydratase complex C
IDA
SceS000001217
S000003486
GO:0000324 fungal-type vacuole C
IDA
SceS000003486
S000001217
GO:0001917 photoreceptor inner segment C
IDA
MmuMGI:95394
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000003486
S000001217
GO:0005575 cellular_component C
ND
SceS000006202
S000005920
GO:0005622 intracellular C
IDA
MmuMGI:95394
GO:0005624 membrane fraction C
ISO
MmuMGI:95395
GO:0005625 soluble fraction C
IDA
SceS000001217
ISO
MmuMGI:95393
MGI:95394
GO:0005626 insoluble fraction C
ISO
MmuMGI:95393
MGI:95394
GO:0005634 nucleus C
IDA
AthAt2g36530
SpoSPBC1815.01
GO:0005737 cytoplasm C
IDA
AthAt2g36530
MmuMGI:95394
SceS000003486
S000004942
ISO
MmuMGI:95394
GO:0005739 mitochondrion C
IDA
AthAt2g36530
SceS000001217
S000003486
GO:0005740 mitochondrial envelope C
IDA
AthAt2g36530
GO:0005811 lipid particle C
IDA
DmeFBgn0000579
GO:0005829 cytosol C
IDA
SpoSPBC1815.01
GO:0005886 plasma membrane C
IDA
AthAt2g36530
GO:0009507 chloroplast C
IDA
AthAt1g74030
At2g36530
GO:0009898 internal side of plasma membrane C
IDA
SceS000001217
GO:0016020 membrane C
IDA
AthAt2g36530
GO:0019717 synaptosome C
ISO
MmuMGI:95393
MGI:95394
GO:0043025 neuronal cell body C
IDA
MmuMGI:95394
GO:0043204 perikaryon C
IDA
MmuMGI:95394
GO:0048046 apoplast C
IDA
AthAt2g36530
GO:0004634 phosphopyruvate hydratase activity F
IDA
AthAt1g74030
At2g36530
MmuMGI:95393
IMP
SceS000001217
S000003486
ISA
SceS000004942
S000006202
S000005920
ISO
MmuMGI:95393
MGI:95395
MGI:95394
ISS
AthAt2g36530
At1g74030
DmeFBgn0000579
SceS000004942
SpoSPBC1815.01
SPBPB21E7.01c
GO:0005507 copper ion binding F
IDA
AthAt2g36530
GO:0005515 protein binding F
IPI
MmuMGI:95393
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:95393
MGI:95394
MGI:95395
GO:0046982 protein heterodimerization activity F
ISO
MmuMGI:95394
MGI:95393
MGI:95395
GO:0000003 reproduction P
IMP
CelWBGene00011884
GO:0001701 in utero embryonic development P
IMP
MmuMGI:95393
GO:0002119 nematode larval development P
IMP
CelWBGene00011884
GO:0006066 alcohol metabolic process P
RCA
SceS000001217
S000003486
GO:0006082 organic acid metabolic process P
RCA
SceS000001217
S000003486
GO:0006094 gluconeogenesis P
IEP
SceS000001217
S000003486
ISO
MmuMGI:95394
ISS
PfaPF10_0155
GO:0006096 glycolysis P
IMP
SceS000001217
S000003486
ISO
MmuMGI:95394
ISS
SpoSPBC1815.01
SPBPB21E7.01c
NAS
DmeFBgn0000579
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00011884
GO:0008150 biological_process P
ND
SceS000006202
S000004942
S000005920
GO:0008152 metabolic process P
IDA
MmuMGI:95393
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00011884
GO:0009409 response to cold P
IMP
AthAt2g36530
GO:0009416 response to light stimulus P
IMP
AthAt2g36530
GO:0009651 response to salt stress P
IEP
AthAt2g36530
GO:0009737 response to abscisic acid stimulus P
IEP
AthAt2g36530
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011884
GO:0010090 trichome morphogenesis P
IMP
AthAt1g74030
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000001217
S000003486
IMP
SceS000003486
S000001217
GO:0040007 growth P
IMP
CelWBGene00011884
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011884
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00011884
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00011884
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003486
S000001217
GO:0046686 response to cadmium ion P
IEP
AthAt2g36530

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBPB21E7.01c
(Q8NKC2)		 YHR174W
(S000001217)
SPBC1815.01
(P40370)		 YHR174W
(S000001217)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000015 phosphopyruvate hydratase complex C
IDA
SceS000001217
GO:0000324 fungal-type vacuole C
IDA
SceS000001217
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000001217
GO:0005625 soluble fraction C
IDA
SceS000001217
GO:0005634 nucleus C
IDA
SpoSPBC1815.01
GO:0005739 mitochondrion C
IDA
SceS000001217
GO:0005829 cytosol C
IDA
SpoSPBC1815.01
GO:0009898 internal side of plasma membrane C
IDA
SceS000001217
GO:0004634 phosphopyruvate hydratase activity F
IMP
SceS000001217
ISS
SpoSPBC1815.01
SPBPB21E7.01c
GO:0006066 alcohol metabolic process P
RCA
SceS000001217
GO:0006082 organic acid metabolic process P
RCA
SceS000001217
GO:0006094 gluconeogenesis P
IEP
SceS000001217
GO:0006096 glycolysis P
IMP
SceS000001217
ISS
SpoSPBC1815.01
SPBPB21E7.01c
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000001217
IMP
SceS000001217
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000001217

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Query species:

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GO info in one table:

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