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Search term: YHR186C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name KOG1
SGD link S000001229
Alternative ID YHR186C
Description Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors
Synonyms YHR186C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1517 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Guanine nucleotide binding protein MIP1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g08850 GI:6403497
Arabidopsis thaliana (Ath) At5g01770 GI:15241060
Caenorhabditis elegans (Cel) CE28535
(WBGene00000911)
GI:17538648 Q17901
Caenorhabditis elegans (Cel) CE28536 GI:17538646 Q17901
Drosophila melanogaster (Dme) 7290674 GI:7290674 Q9W437
Homo sapiens (Hsa) Hs22066458 GI:22066458
Saccharomyces cerevisiae (Sce) YHR186c
(S000001229)
GI:6321980 P38873
Schizosaccharomyces pombe (Spo) SPAC57A7.11 GI:19114282 P87141


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001229
GO:0005624 membrane fraction C
IDA
SceS000001229
GO:0005737 cytoplasm C
IDA
SpoSPAC57A7.11
GO:0005739 mitochondrion C
IDA
SceS000001229
GO:0005886 plasma membrane C
IDA
SceS000001229
GO:0031931 TORC1 complex C
IDA
SpoSPAC57A7.11
IPI
SceS000001229
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g01770
At3g08850
GO:0000166 nucleotide binding F
ISS
AthAt5g01770
At3g08850
GO:0003674 molecular_function F
ND
SceS000001229
GO:0005515 protein binding F
IPI
AthAt3g08850
SpoSPAC57A7.11
GO:0001558 regulation of cell growth P
IPI
SceS000001229
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00000911
GO:0008406 gonad development P
IMP
CelWBGene00000911
GO:0009267 cellular response to starvation P
IMP
SceS000001229
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthAt3g08850
GO:0016049 cell growth P
IMP
AthAt3g08850
At5g01770
GO:0031137 regulation of conjugation with cellular
fusion
P
IGI
SpoSPAC57A7.11
IPI
SpoSPAC57A7.11
GO:0031929 TOR signaling cascade P
IC
SceS000001229
TAS
SpoSPAC57A7.11
GO:0040024 dauer larval development P
IMP
CelWBGene00000911
GO:0050801 ion homeostasis P
RCA
SceS000001229

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
80210

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RPTOR GI:22094987
Pan troglodytes (Ptr) RPTOR GI:114670895
Canis familiaris (Cfa) RPTOR GI:73964853
Mus musculus (Mmu) Rptor
(MGI:1921620)
GI:30061325 A4FUW1
Rattus norvegicus (Rno) Rptor GI:62657463
Gallus gallus (Gga) RPTOR GI:118099838
Drosophila melanogaster (Dme) raptor
(FBgn0029840)
GI:24640048
Anopheles gambiae (Aga) AgaP_AGAP010035 GI:158299070
Schizosaccharomyces pombe (Spo) mip1
(SPAC57A7.11)
GI:19114282 P87141
Saccharomyces cerevisiae (Sce) KOG1
(S000001229)
GI:6321980 P38873
Kluyveromyces lactis (Kla) KLLA0A09471g GI:50302953
Eremothecium gossypii (Ego) AGOS_ADR331C GI:45188204
Magnaporthe grisea (Mgr) MGG_02874 GI:145609920
Neurospora crassa (Ncr) NCU00621.1 GI:32408641
Arabidopsis thaliana (Ath) RAPTOR1 GI:18398267
Arabidopsis thaliana (Ath) RAPTOR2 GI:186519236
Oryza sativa (Osa) Os12g0110000 GI:115486948


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001229
GO:0005624 membrane fraction C
IDA
SceS000001229
GO:0005737 cytoplasm C
IDA
SpoSPAC57A7.11
GO:0005739 mitochondrion C
IDA
SceS000001229
GO:0005829 cytosol C
EXP
HsaRPTOR
GO:0005886 plasma membrane C
IDA
SceS000001229
GO:0030425 dendrite C
ISO
MmuMGI:1921620
GO:0031931 TORC1 complex C
IDA
HsaRPTOR
SpoSPAC57A7.11
IPI
SceS000001229
ISO
MmuMGI:1921620
GO:0043025 neuronal cell body C
ISO
MmuMGI:1921620
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthRAPTOR1
RAPTOR2
GO:0000166 nucleotide binding F
ISS
AthRAPTOR1
RAPTOR2
GO:0003674 molecular_function F
ND
SceS000001229
GO:0005515 protein binding F
IPI
AthRAPTOR1
HsaRPTOR
SpoSPAC57A7.11
GO:0019901 protein kinase binding F
ISO
MmuMGI:1921620
GO:0032403 protein complex binding F
IPI
HsaRPTOR
GO:0001558 regulation of cell growth P
IPI
SceS000001229
GO:0001934 positive regulation of protein amino acid
phosphorylation
P
IMP
DmeFBgn0029840
GO:0001938 positive regulation of endothelial cell
proliferation
P
ISO
MmuMGI:1921620
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0029840
GO:0008361 regulation of cell size P
IMP
HsaRPTOR
GO:0009267 cellular response to starvation P
IMP
SceS000001229
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthRAPTOR1
GO:0016049 cell growth P
IMP
AthRAPTOR1
RAPTOR2
GO:0031137 regulation of conjugation with cellular
fusion
P
IGI
SpoSPAC57A7.11
IPI
SpoSPAC57A7.11
GO:0031669 cellular response to nutrient levels P
IMP
HsaRPTOR
GO:0031929 TOR signaling cascade P
IC
SceS000001229
TAS
SpoSPAC57A7.11
GO:0032008 positive regulation of TOR signaling
cascade
P
IDA
HsaRPTOR
GO:0042325 regulation of phosphorylation P
ISO
MmuMGI:1921620
GO:0050801 ion homeostasis P
RCA
SceS000001229

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2698

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga12330 ENSANGP00000026347
Ashbya gossypii (Ago) ago2072 ADR331C
Arabidopsis thaliana (Ath) ath12953 At3g08850.1
Arabidopsis thaliana (Ath) ath22319 At5g01770.1
Caenorhabditis elegans (Cel) cel1726 C10C5.6a
(CE28535;
WBGene00000911)
Caenorhabditis elegans (Cel) cel1727 C10C5.6b
(CE28536)
Candida glabrata (Cgl) cgl5240 CAGL0M13409g
Cryptococcus neoformans (Cne) cne839 163.m06173
Dictyostelium discoideum (Ddi) ddi4160 DDB0191024
Debaryomyces hansenii (Dha) dha3609 DEHA0E08327g
Drosophila melanogaster (Dme) dme16678 CG4320-PA
(FBgn0029840)
Danio rerio (Dre) dre30003 ENSDARP00000031922
Gallus gallus (Gga) gga16435 ENSGALP00000011224
(RPTOR)
Gallus gallus (Gga) gga16437 ENSGALP00000011225
Gallus gallus (Gga) gga16436 ENSGALP00000011226
Homo sapiens (Hsa) hsa14485 ENSP00000307272
(RPTOR)
Q8N122-1
Kluyveromyces lactis (Kla) kla411 KLLA0A09471g
Mus musculus (Mmu) mmu5284 ENSMUSP00000072853
Mus musculus (Mmu) mmu5283 ENSMUSP00000075761
Neurospora crassa (Ncr) ncr602 NCU00621.2
Oryza sativa (Osa) osa59816 6543.m00133
Oryza sativa (Osa) osa60252 6558.m00147
Oryza sativa (Osa) osa60290 6559.m00124
Rattus norvegicus (Rno) rno6536 ENSRNOP00000005337
(RGD:1311784)
Saccharomyces cerevisiae (Sce) sce2962 YHR186C
(S000001229)
Schizosaccharomyces pombe (Spo) spo2792 SPAC57A7.11 P87141
Yarrowia lipolytica (Yli) yli4153 YALI0E06919g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001229
GO:0005624 membrane fraction C
IDA
SceS000001229
GO:0005737 cytoplasm C
IDA
SpoSPAC57A7.11
GO:0005739 mitochondrion C
IDA
SceS000001229
GO:0005886 plasma membrane C
IDA
SceS000001229
GO:0031931 TORC1 complex C
IDA
SpoSPAC57A7.11
IPI
SceS000001229
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g01770
At3g08850
GO:0000166 nucleotide binding F
ISS
AthAt5g01770
At3g08850
GO:0003674 molecular_function F
ND
SceS000001229
GO:0005515 protein binding F
IPI
AthAt3g08850
SpoSPAC57A7.11
GO:0001558 regulation of cell growth P
IPI
SceS000001229
GO:0001934 positive regulation of protein amino acid
phosphorylation
P
IMP
DmeFBgn0029840
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0029840
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00000911
GO:0008406 gonad development P
IMP
CelWBGene00000911
GO:0009267 cellular response to starvation P
IMP
SceS000001229
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthAt3g08850
GO:0016049 cell growth P
IMP
AthAt3g08850
At5g01770
GO:0031137 regulation of conjugation with cellular
fusion
P
IGI
SpoSPAC57A7.11
IPI
SpoSPAC57A7.11
GO:0031929 TOR signaling cascade P
IC
SceS000001229
TAS
SpoSPAC57A7.11
GO:0040024 dauer larval development P
IMP
CelWBGene00000911
GO:0050801 ion homeostasis P
RCA
SceS000001229

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC57A7.11
(P87141)
YHR186C
(S000001229)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001229
GO:0005624 membrane fraction C
IDA
SceS000001229
GO:0005737 cytoplasm C
IDA
SpoSPAC57A7.11
GO:0005739 mitochondrion C
IDA
SceS000001229
GO:0005886 plasma membrane C
IDA
SceS000001229
GO:0031931 TORC1 complex C
IDA
SpoSPAC57A7.11
IPI
SceS000001229
GO:0003674 molecular_function F
ND
SceS000001229
GO:0005515 protein binding F
IPI
SpoSPAC57A7.11
GO:0001558 regulation of cell growth P
IPI
SceS000001229
GO:0009267 cellular response to starvation P
IMP
SceS000001229
GO:0031137 regulation of conjugation with cellular
fusion
P
IGI
SpoSPAC57A7.11
IPI
SpoSPAC57A7.11
GO:0031929 TOR signaling cascade P
IC
SceS000001229
TAS
SpoSPAC57A7.11
GO:0050801 ion homeostasis P
RCA
SceS000001229

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk