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Search term: YHR190W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG9
SGD link S000001233
Alternative ID YHR190W
Description Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
Synonyms YHR190W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1459 A--HYP-

KOGs classification KOGs description
METABOLISM Squalene synthetase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g34640 GI:15236168
Arabidopsis thaliana (Ath) At4g34650 GI:15236169
Arabidopsis thaliana (Ath) At5g17230 GI:15237933
Homo sapiens (Hsa) Hs4758350 GI:4758350
Saccharomyces cerevisiae (Sce) YHR190w
(S000001233)
GI:6321984 P29704
Schizosaccharomyces pombe (Spo) SPBC646.05c GI:19112155 P36596


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005741 mitochondrial outer membrane C
IDA
SceS000001233
GO:0005783 endoplasmic reticulum C
IDA
AthAt4g34640
SceS000001233
SpoSPBC646.05c
IGI
SpoSPBC646.05c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPBC646.05c
TAS
AthAt4g34640
GO:0005792 microsome C
IDA
SceS000001233
GO:0005886 plasma membrane C
IDA
AthAt4g34640
GO:0009507 chloroplast C
IDA
AthAt5g17230
GO:0016021 integral to membrane C
IDA
SceS000001233
GO:0042175 nuclear membrane-endoplasmic reticulum
network
C
IDA
SpoSPBC646.05c
GO:0004310 farnesyl-diphosphate farnesyltransferase
activity
F
IDA
AthAt4g34640
At4g34650
SceS000001233
IGI
SpoSPBC646.05c
ISS
AthAt4g34650
At4g34640
GO:0005515 protein binding F
IPI
SpoSPBC646.05c
GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase
activity
F
ISS
AthAt5g17230
TAS
AthAt5g17230
GO:0046905 phytoene synthase activity F
TAS
AthAt5g17230
GO:0051996 squalene synthase activity F
IDA
SceS000001233
GO:0006066 alcohol metabolic process P
RCA
SceS000001233
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPBC646.05c
IMP
SceS000001233
GO:0016117 carotenoid biosynthetic process P
IMP
AthAt5g17230
GO:0016126 sterol biosynthetic process P
ISS
AthAt4g34650
TAS
AthAt4g34640
GO:0044255 cellular lipid metabolic process P
RCA
SceS000001233

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3281

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FDFT1 GI:67089147
Pan troglodytes (Ptr) FDFT1 GI:114623526
Canis familiaris (Cfa) FDFT1 GI:73993617
Mus musculus (Mmu) Fdft1
(MGI:102706)
GI:34328173 P53798
Rattus norvegicus (Rno) Fdft1
(RGD:61834)
GI:9506591
Gallus gallus (Gga) FDFT1 GI:86129502
Schizosaccharomyces pombe (Spo) erg9
(SPBC646.05c)
GI:19112155 P36596
Saccharomyces cerevisiae (Sce) ERG9
(S000001233)
GI:6321984 P29704
Kluyveromyces lactis (Kla) KLLA0D08866g GI:50306959
Eremothecium gossypii (Ego) AGOS_AFR444C GI:45198962
Magnaporthe grisea (Mgr) MGG_09239 GI:39958237
Neurospora crassa (Ncr) NCU06054.1 GI:32410857
Arabidopsis thaliana (Ath) SQS2 GI:145353033
Arabidopsis thaliana (Ath) SQS1 GI:15236168
Oryza sativa (Osa) Os03g0805100 GI:115456049
Oryza sativa (Osa) Os07g0200700 GI:115471061


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005741 mitochondrial outer membrane C
IDA
SceS000001233
GO:0005783 endoplasmic reticulum C
IDA
AthSQS1
HsaFDFT1
SceS000001233
SpoSPBC646.05c
IGI
SpoSPBC646.05c
GO:0005789 endoplasmic reticulum membrane C
EXP
HsaFDFT1
IDA
SpoSPBC646.05c
TAS
AthSQS1
GO:0005792 microsome C
IDA
SceS000001233
ISO
MmuMGI:102706
GO:0005886 plasma membrane C
IDA
AthSQS1
GO:0016021 integral to membrane C
IDA
SceS000001233
GO:0042175 nuclear membrane-endoplasmic reticulum
network
C
IDA
SpoSPBC646.05c
GO:0004310 farnesyl-diphosphate farnesyltransferase
activity
F
EXP
HsaFDFT1
IDA
AthSQS2
SQS1
SceS000001233
IGI
SpoSPBC646.05c
ISO
MmuMGI:102706
ISS
AthSQS2
SQS1
GO:0005515 protein binding F
IPI
HsaFDFT1
SpoSPBC646.05c
GO:0051996 squalene synthase activity F
IDA
SceS000001233
GO:0006066 alcohol metabolic process P
RCA
SceS000001233
GO:0006694 steroid biosynthetic process P
TAS
HsaFDFT1
GO:0006695 cholesterol biosynthetic process P
ISO
MmuMGI:102706
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPBC646.05c
IMP
SceS000001233
GO:0016126 sterol biosynthetic process P
ISS
AthSQS2
TAS
AthSQS1
GO:0044255 cellular lipid metabolic process P
RCA
SceS000001233
GO:0045338 farnesyl diphosphate metabolic
process
P
ISO
MmuMGI:102706

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3730

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago3636 AFR444C
Arabidopsis thaliana (Ath) ath21609 At4g34640.1
Arabidopsis thaliana (Ath) ath21610 At4g34650.1
Candida glabrata (Cgl) cgl4966 CAGL0M07095g
Cryptococcus neoformans (Cne) cne5634 179.m00496
Cryptococcus neoformans (Cne) cne5635 179.m00497
Dictyostelium discoideum (Ddi) ddi13477 DDB0231376
Debaryomyces hansenii (Dha) dha2440 DEHA0D03245g
Danio rerio (Dre) dre27505 ENSDARP00000030618
Takifugu rubripes (Fru) fru24414 SINFRUP00000149927
Gallus gallus (Gga) gga16218 ENSGALP00000026843
(FDFT1)
Q5ZKW1
Gallus gallus (Gga) gga16219 ENSGALP00000026844
Homo sapiens (Hsa) hsa29922 ENSP00000220584
(FDFT1)
P37268
Kluyveromyces lactis (Kla) kla2456 KLLA0D08866g
Mus musculus (Mmu) mmu8354 ENSMUSP00000055313
(MGI:102706)
Q3TS40
Neurospora crassa (Ncr) ncr5884 NCU06054.2
Oryza sativa (Osa) osa54703 6315.m00122
Oryza sativa (Osa) osa87393 9231.m00108
Oryza sativa (Osa) osa87917 9532.m00150
Rattus norvegicus (Rno) rno11537 ENSRNOP00000029808
(RGD:61834)
Q02769
Saccharomyces cerevisiae (Sce) sce2966 YHR190W
(S000001233)
Schizosaccharomyces pombe (Spo) spo4797 SPBC646.05c P36596
Yarrowia lipolytica (Yli) yli334 YALI0A10076g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005741 mitochondrial outer membrane C
IDA
SceS000001233
GO:0005783 endoplasmic reticulum C
IDA
AthAt4g34640
SceS000001233
SpoSPBC646.05c
IGI
SpoSPBC646.05c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPBC646.05c
TAS
AthAt4g34640
GO:0005792 microsome C
IDA
SceS000001233
ISO
MmuMGI:102706
GO:0005886 plasma membrane C
IDA
AthAt4g34640
GO:0016021 integral to membrane C
IDA
SceS000001233
GO:0042175 nuclear membrane-endoplasmic reticulum
network
C
IDA
SpoSPBC646.05c
GO:0004310 farnesyl-diphosphate farnesyltransferase
activity
F
IDA
AthAt4g34640
At4g34650
SceS000001233
IGI
SpoSPBC646.05c
ISO
MmuMGI:102706
ISS
AthAt4g34650
At4g34640
GO:0005515 protein binding F
IPI
SpoSPBC646.05c
GO:0051996 squalene synthase activity F
IDA
SceS000001233
GO:0006066 alcohol metabolic process P
RCA
SceS000001233
GO:0006695 cholesterol biosynthetic process P
ISO
MmuMGI:102706
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPBC646.05c
IMP
SceS000001233
GO:0016126 sterol biosynthetic process P
ISS
AthAt4g34650
TAS
AthAt4g34640
GO:0044255 cellular lipid metabolic process P
RCA
SceS000001233
GO:0045338 farnesyl diphosphate metabolic
process
P
ISO
MmuMGI:102706

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC646.05c
(P36596)
YHR190W
(S000001233)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005741 mitochondrial outer membrane C
IDA
SceS000001233
GO:0005783 endoplasmic reticulum C
IDA
SceS000001233
SpoSPBC646.05c
IGI
SpoSPBC646.05c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPBC646.05c
GO:0005792 microsome C
IDA
SceS000001233
GO:0016021 integral to membrane C
IDA
SceS000001233
GO:0042175 nuclear membrane-endoplasmic reticulum
network
C
IDA
SpoSPBC646.05c
GO:0004310 farnesyl-diphosphate farnesyltransferase
activity
F
IDA
SceS000001233
IGI
SpoSPBC646.05c
GO:0005515 protein binding F
IPI
SpoSPBC646.05c
GO:0051996 squalene synthase activity F
IDA
SceS000001233
GO:0006066 alcohol metabolic process P
RCA
SceS000001233
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPBC646.05c
IMP
SceS000001233
GO:0044255 cellular lipid metabolic process P
RCA
SceS000001233

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Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk