YOGY Home YOGY Help

Search term: YIL002C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name INP51
SGD link S000001264
Alternative ID YIL002C
Description Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth
Synonyms YIL002C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0566 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin), INP51/INP52/INP53 family

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE28239
(WBGene00006763)		 GI:17541150
Caenorhabditis elegans (Cel) CE29050 GI:17541152
Drosophila melanogaster (Dme) 7291368
(FBgn0034691)		 GI:18497296
Homo sapiens (Hsa) Hs4507335 GI:4507335
Homo sapiens (Hsa) Hs14747866 GI:14747866
Saccharomyces cerevisiae (Sce) YIL002c
(S000001264)		 GI:6322189 P40559
Saccharomyces cerevisiae (Sce) YNL106c
(S000005050)		 GI:6324224 P50942
Saccharomyces cerevisiae (Sce) YOR109w
(S000005635)		 GI:6324683 Q12271
Schizosaccharomyces pombe (Spo) SPBC2G2.02 GI:19113223 O43001
Schizosaccharomyces pombe (Spo) SPBC577.13 GI:19112103 Q9USQ6
Encephalitozoon cuniculi (Ecu) ECU08g1420 GI:19173467 Q8SUM4
Caenorhabditis elegans (Cel) CE28239
(WBGene00006763)		 GI:17541150
Caenorhabditis elegans (Cel) CE29050 GI:17541152
Drosophila melanogaster (Dme) 7291368
(FBgn0034691)		 GI:18497296
Homo sapiens (Hsa) Hs4507335 GI:4507335
Homo sapiens (Hsa) Hs14747866 GI:14747866
Saccharomyces cerevisiae (Sce) YIL002c
(S000001264)		 GI:6322189 P40559
Saccharomyces cerevisiae (Sce) YNL106c
(S000005050)		 GI:6324224 P50942
Saccharomyces cerevisiae (Sce) YOR109w
(S000005635)		 GI:6324683 Q12271
Schizosaccharomyces pombe (Spo) SPBC2G2.02 GI:19113223 O43001
Schizosaccharomyces pombe (Spo) SPBC577.13 GI:19112103 Q9USQ6
Encephalitozoon cuniculi (Ecu) ECU08g1420 GI:19173467 Q8SUM4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000005635
S000001264
GO:0005737 cytoplasm C
IDA
SceS000001264
S000005050
S000005635
SpoSPBC577.13
GO:0005829 cytosol C
IDA
SpoSPBC2G2.02
GO:0008021 synaptic vesicle C
ISS
CelWBGene00006763
GO:0012506 vesicle membrane C
IDA
DmeFBgn0034691
GO:0030479 actin cortical patch C
IDA
SceS000005050
S000005635
IPI
SceS000005050
GO:0032153 cell division site C
IDA
SpoSPBC2G2.02
GO:0042598 vesicular fraction C
IDA
SceS000005050
S000005635
GO:0043195 terminal button C
IDA
DmeFBgn0034691
GO:0043332 mating projection tip C
IDA
SceS000005050
GO:0045202 synapse C
IDA
CelWBGene00006763
GO:0051286 cell tip C
IDA
SpoSPBC2G2.02
GO:0004437 inositol or phosphatidylinositol phosphatase
activity		 F
ISS
CelWBGene00006763
GO:0004438 phosphatidylinositol-3-phosphatase
activity		 F
IDA
SceS000005050
S000005635
RCA
SceS000001264
GO:0004439 phosphatidylinositol-4,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000001264
S000005050
S000005635
IMP
SceS000001264
S000005050
S000005635
ISS
SpoSPBC2G2.02
GO:0004445 inositol-polyphosphate 5-phosphatase
activity		 F
IDA
DmeFBgn0034691
SpoSPBC2G2.02
ISS
SpoSPBC577.13
GO:0042577 lipid phosphatase activity F
RCA
SceS000001264
GO:0043812 phosphatidylinositol-4-phosphate phosphatase
activity		 F
IDA
SceS000005635
S000005050
RCA
SceS000001264
GO:0043813 phosphatidylinositol-3,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000005050
S000005635
RCA
SceS000001264
GO:0046030 inositol trisphosphate phosphatase
activity		 F
NAS
DmeFBgn0034691
GO:0001956 positive regulation of neurotransmitter
secretion		 P
IMP
CelWBGene00006763
GO:0006414 translational elongation P
RCA
SceS000005635
GO:0006897 endocytosis P
ISS
SpoSPBC577.13
SPBC2G2.02
GO:0006936 muscle contraction P
IMP
CelWBGene00006763
GO:0006970 response to osmotic stress P
RCA
SceS000005050
GO:0007010 cytoskeleton organization P
IMP
CelWBGene00006763
GO:0007032 endosome organization P
IMP
CelWBGene00006763
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0034691
GO:0015812 gamma-aminobutyric acid transport P
IMP
CelWBGene00006763
GO:0015870 acetylcholine transport P
IMP
CelWBGene00006763
GO:0016050 vesicle organization P
IMP
CelWBGene00006763
GO:0016185 synaptic vesicle budding from presynaptic
membrane		 P
IMP
CelWBGene00006763
GO:0016191 synaptic vesicle uncoating P
IMP
CelWBGene00006763
GO:0016311 dephosphorylation P
NAS
DmeFBgn0034691
GO:0033554 cellular response to stress P
IEP
SpoSPBC577.13
GO:0040011 locomotion P
IMP
CelWBGene00006763
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00006763
GO:0043050 pharyngeal pumping P
IMP
CelWBGene00006763
GO:0043058 regulation of backward locomotion P
IMP
CelWBGene00006763
GO:0043059 regulation of forward locomotion P
IMP
CelWBGene00006763
GO:0045933 positive regulation of muscle contraction P
IMP
CelWBGene00006763
GO:0046488 phosphatidylinositol metabolic
process		 P
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0046856 phosphoinositide dephosphorylation P
IDA
SceS000005050
S000001264
S000005635
IMP
SceS000005050
S000001264
S000005635
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0048017 inositol lipid-mediated signaling P
IC
SpoSPBC2G2.02
SPBC577.13
GO:0048212 Golgi vesicle uncoating P
IMP
CelWBGene00006763
GO:0048488 synaptic vesicle endocytosis P
IMP
CelWBGene00006763
DmeFBgn0034691
TAS
DmeFBgn0034691
GO:0048489 synaptic vesicle transport P
IMP
CelWBGene00006763
GO:0048790 maintenance of presynaptic active zone
structure		 P
IMP
DmeFBgn0034691
GO:0050803 regulation of synapse structure and
activity		 P
IMP
DmeFBgn0034691
GO:0051049 regulation of transport P
RCA
SceS000005050
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000005050

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56198

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) INP51
(S000001264)		 GI:6322189 P40559
Kluyveromyces lactis (Kla) KLLA0D13860g GI:50307403
Eremothecium gossypii (Ego) AGOS_ADL002C GI:45187872


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000001264
GO:0005737 cytoplasm C
IDA
SceS000001264
GO:0004438 phosphatidylinositol-3-phosphatase
activity		 F
RCA
SceS000001264
GO:0004439 phosphatidylinositol-4,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000001264
IMP
SceS000001264
GO:0042577 lipid phosphatase activity F
RCA
SceS000001264
GO:0043812 phosphatidylinositol-4-phosphate phosphatase
activity		 F
RCA
SceS000001264
GO:0043813 phosphatidylinositol-3,5-bisphosphate
5-phosphatase activity		 F
RCA
SceS000001264
GO:0046856 phosphoinositide dephosphorylation P
IDA
SceS000001264
IMP
SceS000001264

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13279

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1740 ADL002C
Candida glabrata (Cgl) cgl3081 CAGL0J02134g
Debaryomyces hansenii (Dha) dha1263 DEHA0B13431g
Kluyveromyces lactis (Kla) kla2679 KLLA0D13860g
Oryza sativa (Osa) osa15717 3047.m00131
Oryza sativa (Osa) osa62091 6496.m00127
Oryza sativa (Osa) osa68257 6905.m00131
Saccharomyces cerevisiae (Sce) sce3009 YIL002C
(S000001264)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000001264
GO:0005737 cytoplasm C
IDA
SceS000001264
GO:0004438 phosphatidylinositol-3-phosphatase
activity		 F
RCA
SceS000001264
GO:0004439 phosphatidylinositol-4,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000001264
IMP
SceS000001264
GO:0042577 lipid phosphatase activity F
RCA
SceS000001264
GO:0043812 phosphatidylinositol-4-phosphate phosphatase
activity		 F
RCA
SceS000001264
GO:0043813 phosphatidylinositol-3,5-bisphosphate
5-phosphatase activity		 F
RCA
SceS000001264
GO:0046856 phosphoinositide dephosphorylation P
IDA
SceS000001264
IMP
SceS000001264

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC577.13
(Q9USQ6)		 YIL002C
(S000001264)
SPBC2G2.02
(O43001)		 YIL002C
(S000001264)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000001264
GO:0005737 cytoplasm C
IDA
SceS000001264
SpoSPBC577.13
GO:0005829 cytosol C
IDA
SpoSPBC2G2.02
GO:0032153 cell division site C
IDA
SpoSPBC2G2.02
GO:0051286 cell tip C
IDA
SpoSPBC2G2.02
GO:0004438 phosphatidylinositol-3-phosphatase
activity		 F
RCA
SceS000001264
GO:0004439 phosphatidylinositol-4,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000001264
IMP
SceS000001264
ISS
SpoSPBC2G2.02
GO:0004445 inositol-polyphosphate 5-phosphatase
activity		 F
IDA
SpoSPBC2G2.02
ISS
SpoSPBC577.13
GO:0042577 lipid phosphatase activity F
RCA
SceS000001264
GO:0043812 phosphatidylinositol-4-phosphate phosphatase
activity		 F
RCA
SceS000001264
GO:0043813 phosphatidylinositol-3,5-bisphosphate
5-phosphatase activity		 F
RCA
SceS000001264
GO:0006897 endocytosis P
ISS
SpoSPBC577.13
SPBC2G2.02
GO:0033554 cellular response to stress P
IEP
SpoSPBC577.13
GO:0046488 phosphatidylinositol metabolic
process		 P
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0046856 phosphoinositide dephosphorylation P
IDA
SceS000001264
IMP
SceS000001264
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0048017 inositol lipid-mediated signaling P
IC
SpoSPBC2G2.02
SPBC577.13

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk