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Search term: YIL033C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BCY1
SGD link S000001295
Alternative ID YIL033C
Description Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
Synonyms YIL033C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1113 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING cAMP-dependent protein kinase types I and II, regulatory subunit

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE04821 GI:17569325
Caenorhabditis elegans (Cel) CE28749 GI:17569323
Drosophila melanogaster (Dme) 7296360 GI:7296360
Drosophila melanogaster (Dme) 7303815 GI:7303815
Homo sapiens (Hsa) Hs4506063
(PRKAR1A)		 GI:4506063 P10644
Homo sapiens (Hsa) Hs22062373 GI:22062373
Homo sapiens (Hsa) Hs18201890
(C20orf152)		 GI:18201890 Q96M20
Homo sapiens (Hsa) Hs4506065 GI:4506065
Homo sapiens (Hsa) Hs4758958
(PRKAR2A)		 GI:4758958 P13861
Saccharomyces cerevisiae (Sce) YIL033c
(S000001295)		 GI:6322156 P07278
Schizosaccharomyces pombe (Spo) SPAC8C9.03 GI:19115186 P36600
Encephalitozoon cuniculi (Ecu) ECU08g0930 GI:19173420 Q8SRB5
Caenorhabditis elegans (Cel) CE04821 GI:17569325
Caenorhabditis elegans (Cel) CE28749 GI:17569323
Drosophila melanogaster (Dme) 7296360 GI:7296360
Drosophila melanogaster (Dme) 7303815 GI:7303815
Homo sapiens (Hsa) Hs4506063
(PRKAR1A)		 GI:4506063 P10644
Homo sapiens (Hsa) Hs22062373 GI:22062373
Homo sapiens (Hsa) Hs18201890
(C20orf152)		 GI:18201890 Q96M20
Homo sapiens (Hsa) Hs4506065 GI:4506065
Homo sapiens (Hsa) Hs4758958
(PRKAR2A)		 GI:4758958 P13861
Saccharomyces cerevisiae (Sce) YIL033c
(S000001295)		 GI:6322156 P07278
Schizosaccharomyces pombe (Spo) SPAC8C9.03 GI:19115186 P36600
Encephalitozoon cuniculi (Ecu) ECU08g0930 GI:19173420 Q8SRB5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
TAS
HsaPRKAR2A
GO:0005634 nucleus C
IDA
SceS000001295
SpoSPAC8C9.03
GO:0005737 cytoplasm C
IDA
SceS000001295
GO:0005829 cytosol C
EXP
HsaPRKAR1A
PRKAR2A
IDA
SpoSPAC8C9.03
GO:0005886 plasma membrane C
IDA
SceS000001295
TAS
HsaPRKAR2A
GO:0043234 protein complex C
IDA
HsaPRKAR1A
GO:0004690 cyclic nucleotide-dependent protein kinase
activity		 F
RCA
SceS000001295
GO:0004691 cAMP-dependent protein kinase activity F
RCA
SceS000001295
GO:0004862 cAMP-dependent protein kinase inhibitor
activity		 F
IDA
SceS000001295
IMP
SceS000001295
GO:0005515 protein binding F
IPI
HsaPRKAR1A
GO:0008603 cAMP-dependent protein kinase regulator
activity		 F
IMP
SpoSPAC8C9.03
NAS
HsaPRKAR2A
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
TAS
HsaPRKAR1A
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001295
GO:0007264 small GTPase mediated signal transduction P
RCA
SceS000001295
GO:0007265 Ras protein signal transduction P
RCA
SceS000001295
GO:0007568 aging P
RCA
SceS000001295
GO:0009755 hormone-mediated signaling pathway P
EXP
HsaPRKAR1A
PRKAR2A
GO:0019932 second-messenger-mediated signaling P
RCA
SceS000001295
GO:0023034 intracellular signaling pathway P
TAS
HsaPRKAR2A
PRKAR1A
GO:0033554 cellular response to stress P
IEP
SpoSPAC8C9.03
GO:0034199 activation of protein kinase A
activity		 P
EXP
HsaPRKAR1A
PRKAR2A
GO:0046580 negative regulation of Ras protein signal
transduction		 P
IDA
SceS000001295
IMP
SceS000001295
GO:0051447 negative regulation of meiotic cell
cycle		 P
IGI
SpoSPAC8C9.03

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37666

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PRKAR2B GI:47132585
Pan troglodytes (Ptr) PRKAR2B GI:114615342
Canis familiaris (Cfa) PRKAR2B GI:73981762
Mus musculus (Mmu) Prkar2b
(MGI:97760)		 GI:45598396 P31324
Rattus norvegicus (Rno) Prkar2b
(RGD:3394)		 GI:34864232 34324
Gallus gallus (Gga) PRKAR2B GI:118082103
Schizosaccharomyces pombe (Spo) cgs1
(SPAC8C9.03)		 GI:19115186 P36600
Saccharomyces cerevisiae (Sce) BCY1
(S000001295)		 GI:6322156 P07278
Kluyveromyces lactis (Kla) KLLA0E04070g GI:50308263
Eremothecium gossypii (Ego) AGOS_ADL099C GI:45187774
Magnaporthe grisea (Mgr) MGG_07335 GI:39972039
Neurospora crassa (Ncr) NCU01166.1 GI:32412358


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000267 cell fraction C
ISO
MmuMGI:97760
GO:0005624 membrane fraction C
IDA
HsaPRKAR2B
GO:0005625 soluble fraction C
ISO
MmuMGI:97760
GO:0005626 insoluble fraction C
ISO
MmuMGI:97760
GO:0005634 nucleus C
IDA
SceS000001295
SpoSPAC8C9.03
GO:0005737 cytoplasm C
IDA
SceS000001295
ISO
MmuMGI:97760
GO:0005743 mitochondrial inner membrane C
ISO
MmuMGI:97760
GO:0005829 cytosol C
EXP
HsaPRKAR2B
IDA
SpoSPAC8C9.03
GO:0005886 plasma membrane C
IDA
SceS000001295
GO:0005952 cAMP-dependent protein kinase complex C
ISO
MmuMGI:97760
GO:0045121 membrane raft C
ISO
MmuMGI:97760
GO:0048471 perinuclear region of cytoplasm C
ISO
MmuMGI:97760
GO:0004690 cyclic nucleotide-dependent protein kinase
activity		 F
RCA
SceS000001295
GO:0004691 cAMP-dependent protein kinase activity F
RCA
SceS000001295
GO:0004862 cAMP-dependent protein kinase inhibitor
activity		 F
IDA
SceS000001295
IMP
SceS000001295
GO:0008603 cAMP-dependent protein kinase regulator
activity		 F
IDA
MmuMGI:97760
IMP
SpoSPAC8C9.03
ISO
MmuMGI:97760
GO:0019904 protein domain specific binding F
ISO
MmuMGI:97760
GO:0030552 cAMP binding F
ISO
MmuMGI:97760
GO:0006468 protein amino acid phosphorylation P
TAS
MmuMGI:97760
GO:0006631 fatty acid metabolic process P
IMP
MmuMGI:97760
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001295
GO:0007264 small GTPase mediated signal transduction P
RCA
SceS000001295
GO:0007265 Ras protein signal transduction P
RCA
SceS000001295
GO:0007568 aging P
RCA
SceS000001295
GO:0007612 learning P
IMP
MmuMGI:97760
GO:0008283 cell proliferation P
TAS
MmuMGI:97760
GO:0009755 hormone-mediated signaling pathway P
EXP
HsaPRKAR2B
GO:0009887 organ morphogenesis P
TAS
MmuMGI:97760
GO:0019932 second-messenger-mediated signaling P
RCA
SceS000001295
GO:0023034 intracellular signaling pathway P
TAS
HsaPRKAR2B
GO:0033554 cellular response to stress P
IEP
SpoSPAC8C9.03
GO:0034199 activation of protein kinase A
activity		 P
EXP
HsaPRKAR2B
GO:0042325 regulation of phosphorylation P
IDA
MmuMGI:97760
GO:0045859 regulation of protein kinase activity P
ISO
MmuMGI:97760
GO:0046580 negative regulation of Ras protein signal
transduction		 P
IDA
SceS000001295
IMP
SceS000001295
GO:0050790 regulation of catalytic activity P
IDA
MmuMGI:97760
GO:0051447 negative regulation of meiotic cell
cycle		 P
IGI
SpoSPAC8C9.03

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_468

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1897 ENSANGP00000014053
Anopheles gambiae (Aga) aga294 ENSANGP00000022229
Anopheles gambiae (Aga) aga293 ENSANGP00000022232
Ashbya gossypii (Ago) ago1642 ADL099C
Caenorhabditis elegans (Cel) cel13531 R07E4.6a
(CE39609;
WBGene00002190)
Caenorhabditis elegans (Cel) cel13532 R07E4.6b
(CE28749)
Candida glabrata (Cgl) cgl2749 CAGL0I05236g
Cryptococcus neoformans (Cne) cne2283 181.m08306
Dictyostelium discoideum (Ddi) ddi12183 DDB0214950
Debaryomyces hansenii (Dha) dha83 DEHA0A01903g
Drosophila melanogaster (Dme) dme4201 CG15862-PA
(FBgn0022382)
Drosophila melanogaster (Dme) dme4202 CG15862-PB
(FBgn0022382)
Drosophila melanogaster (Dme) dme4203 CG15862-PC
(FBgn0022382)
Drosophila melanogaster (Dme) dme10481 CG3263-PA
(FBgn0000275)
Drosophila melanogaster (Dme) dme10482 CG3263-PB
(FBgn0000275)
Drosophila melanogaster (Dme) dme10480 CG3263-PC
(FBgn0000275)
Drosophila melanogaster (Dme) dme10483 CG3263-PD
(FBgn0000275)
Danio rerio (Dre) dre17007 ENSDARP00000019613
Danio rerio (Dre) dre19227 ENSDARP00000024266
Danio rerio (Dre) dre28195 ENSDARP00000046625
(LOC571826)
Danio rerio (Dre) dre28194 ENSDARP00000048675
(zgc:153742)		 Q08BH1
Danio rerio (Dre) dre28196 ENSDARP00000050049
Takifugu rubripes (Fru) fru5153 SINFRUP00000134736
Takifugu rubripes (Fru) fru18894 SINFRUP00000146522
Takifugu rubripes (Fru) fru14455 SINFRUP00000146993
Takifugu rubripes (Fru) fru6921 SINFRUP00000163052
Takifugu rubripes (Fru) fru6922 SINFRUP00000163054
Takifugu rubripes (Fru) fru6923 SINFRUP00000171788
Takifugu rubripes (Fru) fru6920 SINFRUP00000177273
Gallus gallus (Gga) gga6358 ENSGALP00000005814
(PRKAR1B)
Gallus gallus (Gga) gga5363 ENSGALP00000011344
(PRKAR2A)
Gallus gallus (Gga) gga5366 ENSGALP00000011345
Gallus gallus (Gga) gga5364 ENSGALP00000011346
Gallus gallus (Gga) gga5365 ENSGALP00000011347
Homo sapiens (Hsa) hsa14232 ENSP00000226090
Homo sapiens (Hsa) hsa22449 ENSP00000265563
(PRKAR2A)		 P13861
Homo sapiens (Hsa) hsa29257 ENSP00000265717
(PRKAR2B)		 P31323
Homo sapiens (Hsa) hsa22448 ENSP00000296446
(PRKAR2A)		 Q9BUB1
Homo sapiens (Hsa) hsa14231 ENSP00000351410
(PRKAR1A)		 P10644
Kluyveromyces lactis (Kla) kla3131 KLLA0E04070g
Mus musculus (Mmu) mmu5600 ENSMUSP00000003079
(MGI:97760)		 P31324
Mus musculus (Mmu) mmu21176 ENSMUSP00000026973
(MGI:97759)		 P12849
Mus musculus (Mmu) mmu28309 ENSMUSP00000035220
(MGI:108025)		 Q8K1M3
Mus musculus (Mmu) mmu5601 ENSMUSP00000039797
(MGI:97760)		 P31324
Mus musculus (Mmu) mmu5062 ENSMUSP00000056500
(MGI:104878)		 Q9DBC7
Neurospora crassa (Ncr) ncr1130 NCU01166.2
Plasmodium falciparum (Pfa) pfa5005 PFL1110c
Rattus norvegicus (Rno) rno24989 ENSRNOP00000012415
(RGD:3394)		 P12369
Rattus norvegicus (Rno) rno29295 ENSRNOP00000027552
(RGD:3393)		 P12368
Rattus norvegicus (Rno) rno8179 ENSRNOP00000033202
(RGD:3392)		 Q3SWU5
Saccharomyces cerevisiae (Sce) sce3047 YIL033C
(S000001295)
Schizosaccharomyces pombe (Spo) spo4546 SPAC8C9.03 P36600
Yarrowia lipolytica (Yli) yli5528 YALI0F04422g