Bahler Lab

Search term: YIL035C

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name CKA1

SGD link S000001297

Alternative ID YIL035C

Description Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases

Synonyms YIL035C

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0668 ACDHYPE

KOGs classification KOGs description

CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Casein kinase II, alpha subunit

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Ath At2g23080

GO:0005634 nucleus C
IDA
Spo SPAC23C11.11

GO:0005654 nucleoplasm C
RCA
Sce S000001297

GO:0005730 nucleolus C
IDA
Spo SPAC23C11.11

GO:0005829 cytosol C
IDA
Spo SPAC23C11.11

GO:0005886 plasma membrane C
IDA
Ath At3g50000

GO:0005956 protein kinase CK2 complex C
IDA
Sce S000005587
S000001297
TAS
Spo SPAC23C11.11

GO:0031931 TORC1 complex C
IDA
Spo SPAC23C11.11

GO:0031932 TORC2 complex C
IDA
Spo SPAC23C11.11

GO:0034456 UTP-C complex C
IDA
Sce S000001297
S000005587

GO:0004674 protein serine/threonine kinase
activity F
IDA
Sce S000001297
S000005587
ISS
Spo SPAC23C11.11

GO:0005515 protein binding F
IPI
Ath At3g50000
Hsa CSNK2A2

GO:0005524 ATP binding F
ISS
Spo SPAC23C11.11

GO:0016301 kinase activity F
IDA
Ath At3g50000
At5g67380
ISS
Ath At3g50000
At5g67380
At2g23070
At2g23080

GO:0030234 enzyme regulator activity F
RCA
Sce S000001297

GO:0047485 protein N-terminus binding F
IPI
Hsa CSNK2A2

GO:0000003 reproduction P
IMP
Cel WBGene00002191

GO:0006356 regulation of transcription from RNA polymerase I
promoter P
IDA
Sce S000001297
S000005587

GO:0006359 regulation of transcription from RNA polymerase
III promoter P
IDA
Sce S000001297
S000005587

GO:0006468 protein amino acid phosphorylation P
IC
Spo SPAC23C11.11
IDA
Sce S000005587
S000001297
IMP
Sce S000001297

GO:0006974 response to DNA damage stimulus P
IDA
Sce S000001297
S000005587

GO:0007163 establishment or maintenance of cell
polarity P
IMP
Spo SPAC23C11.11

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00002191

GO:0031929 TOR signaling cascade P
TAS
Spo SPAC23C11.11

GO:0034606 response to hermaphrodite contact P
IMP
Cel WBGene00002191

GO:0034608 vulval location P
IMP
Cel WBGene00002191

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00002191

GO:0040035 hermaphrodite genitalia development P
IMP
Cel WBGene00002191

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

121566

Species Gene ID NCBI link UniProt link

Mus musculus (Mmu) Gm10031 GI:149245220

Mus musculus (Mmu) Csnk2a1
(MGI:88543) GI:31542427 Q60737

Drosophila melanogaster (Dme) CkIIalpha GI:24668866

Anopheles gambiae (Aga) AgaP_AGAP005569 GI:158294401

Saccharomyces cerevisiae (Sce) CKA1
(S000001297) GI:6322154 P15790

Kluyveromyces lactis (Kla) KLLA0E04136g GI:50308269

Eremothecium gossypii (Ego) AGOS_ADL102C GI:45187771

Arabidopsis thaliana (Ath) CKA1 GI:30698301

Arabidopsis thaliana (Ath) CKA2 GI:30693260

Oryza sativa (Osa) Os07g0114400 GI:115470307

Plasmodium falciparum (Pfa) PF11_0096 GI:124803615

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Dme CkIIalpha

GO:0005654 nucleoplasm C
RCA
Sce S000001297

GO:0005737 cytoplasm C
IDA
Dme CkIIalpha

GO:0005829 cytosol C
IDA
Dme CkIIalpha

GO:0005886 plasma membrane C
IDA
Ath CKA2

GO:0005956 protein kinase CK2 complex C
IDA
Dme CkIIalpha
Sce S000001297
ISS
Dme CkIIalpha
Pfa PF11_0096
NAS
Dme CkIIalpha
TAS
Mmu MGI:88543

GO:0034456 UTP-C complex C
IDA
Sce S000001297

GO:0004672 protein kinase activity F
NAS
Dme CkIIalpha

GO:0004674 protein serine/threonine kinase
activity F
IDA
Dme CkIIalpha
Sce S000001297
ISS
Dme CkIIalpha
NAS
Dme CkIIalpha

GO:0005515 protein binding F
IPI
Ath CKA2
Mmu MGI:88543

GO:0008013 beta-catenin binding F
IPI
Mmu MGI:88543

GO:0016301 kinase activity F
IDA
Ath CKA1
CKA2
Mmu MGI:88543
ISS
Ath CKA2
CKA1

GO:0019888 protein phosphatase regulator activity F
IDA
Mmu MGI:88543

GO:0030234 enzyme regulator activity F
RCA
Sce S000001297

GO:0006356 regulation of transcription from RNA polymerase I
promoter P
IDA
Sce S000001297

GO:0006359 regulation of transcription from RNA polymerase
III promoter P
IDA
Sce S000001297

GO:0006468 protein amino acid phosphorylation P
IDA
Dme CkIIalpha
Mmu MGI:88543
Sce S000001297
IMP
Sce S000001297
ISS
Dme CkIIalpha
NAS
Dme CkIIalpha

GO:0006974 response to DNA damage stimulus P
IDA
Sce S000001297

GO:0007411 axon guidance P
IMP
Dme CkIIalpha

GO:0007623 circadian rhythm P
IMP
Dme CkIIalpha

GO:0016055 Wnt receptor signaling pathway P
IDA
Dme CkIIalpha

GO:0022416 bristle development P
IMP
Dme CkIIalpha

GO:0045475 locomotor rhythm P
IMP
Dme CkIIalpha

GO:0046331 lateral inhibition P
IMP
Dme CkIIalpha

GO:0046777 protein amino acid autophosphorylation P
IDA
Mmu MGI:88543

GO:0048749 compound eye development P
IMP
Dme CkIIalpha

GO:0050790 regulation of catalytic activity P
IDA
Mmu MGI:88543

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_730

Species OrthoMCL
sequence Model organism
protein page UniProt link

Anopheles gambiae (Aga) aga986 ENSANGP00000017774

Ashbya gossypii (Ago) ago1639 ADL102C

Ashbya gossypii (Ago) ago1945 ADR204W

Arabidopsis thaliana (Ath) ath9212 At2g23070.1

Arabidopsis thaliana (Ath) ath9213 At2g23080.1

Arabidopsis thaliana (Ath) ath16313 At3g50000.1

Arabidopsis thaliana (Ath) ath28922 At5g67380.1

Caenorhabditis elegans (Cel) cel137 B0205.7
(CE17321;
WBGene00002191)

Candida glabrata (Cgl) cgl1711 CAGL0G02035g

Candida glabrata (Cgl) cgl2747 CAGL0I05192g

Cryptococcus neoformans (Cne) cne1449 180.m00403

Dictyostelium discoideum (Ddi) ddi12128 DDB0185025

Debaryomyces hansenii (Dha) dha630 DEHA0A14080g

Debaryomyces hansenii (Dha) dha1762 DEHA0C07469g

Drosophila melanogaster (Dme) dme10791 CG17520-PA
(FBgn0000258)

Drosophila melanogaster (Dme) dme10793 CG17520-PB
(FBgn0000258)

Drosophila melanogaster (Dme) dme10792 CG17520-PC
(FBgn0000258)

Danio rerio (Dre) dre7486 ENSDARP00000003600
(LOC571171)

Danio rerio (Dre) dre7485 ENSDARP00000006001
(ck2a1) Q803N7

Danio rerio (Dre) dre29489 ENSDARP00000020745

Danio rerio (Dre) dre22067 ENSDARP00000027027
(ck2a2) Q7ZU33

Encephalitozoon cuniculi (Ecu) ecu1253 19173691

Takifugu rubripes (Fru) fru29594 SINFRUP00000138278

Gallus gallus (Gga) gga4341 ENSGALP00000001302
(CSNK2A2) P21869

Gallus gallus (Gga) gga12070 ENSGALP00000009985
(CSNK2A1) P21868

Homo sapiens (Hsa) hsa19634 ENSP00000217244
(CSNK2A1) P68400

Homo sapiens (Hsa) hsa12270 ENSP00000262506
(CSNK2A2) P19784

Homo sapiens (Hsa) hsa19635 ENSP00000339247
(CSNK2A1) P68400

Kluyveromyces lactis (Kla) kla3134 KLLA0E04136g

Kluyveromyces lactis (Kla) kla4820 KLLA0F16467g

Mus musculus (Mmu) mmu15738 ENSMUSP00000039756

Mus musculus (Mmu) mmu26488 ENSMUSP00000055919
(MGI:88547) O54833

Mus musculus (Mmu) mmu1279 ENSMUSP00000079835

Neurospora crassa (Ncr) ncr3028 NCU03124.2

Oryza sativa (Osa) osa50269 5904.m00136

Oryza sativa (Osa) osa51905 5988.m00131

Oryza sativa (Osa) osa66911 6940.m00150

Plasmodium falciparum (Pfa) pfa1044 PF11_0096

Rattus norvegicus (Rno) rno19977 ENSRNOP00000007558
(RGD:621663) P19139

Rattus norvegicus (Rno) rno14545 ENSRNOP00000016386
(RGD:1306882) B4F7A9

Saccharomyces cerevisiae (Sce) sce3049 YIL035C
(S000001297)

Saccharomyces cerevisiae (Sce) sce5795 YOR061W
(S000005587)

Schizosaccharomyces pombe (Spo) spo4936 SPAC23C11.11 P40231

Yarrowia lipolytica (Yli) yli1524 YALI0B18700g

Yarrowia lipolytica (Yli) yli3401 YALI0D16863g

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Ath At2g23080

GO:0005634 nucleus C
IDA
Dme FBgn0000258
Spo SPAC23C11.11

GO:0005654 nucleoplasm C
RCA
Sce S000001297

GO:0005730 nucleolus C
IDA
Spo SPAC23C11.11

GO:0005737 cytoplasm C
IDA
Dme FBgn0000258

GO:0005829 cytosol C
IDA
Dme FBgn0000258
Spo SPAC23C11.11

GO:0005886 plasma membrane C
IDA
Ath At3g50000

GO:0005956 protein kinase CK2 complex C
IDA
Dme FBgn0000258
Sce S000005587
S000001297
ISS
Dme FBgn0000258
Pfa PF11_0096
NAS
Dme FBgn0000258
TAS
Mmu MGI:88547
Spo SPAC23C11.11

GO:0031931 TORC1 complex C
IDA
Spo SPAC23C11.11

GO:0031932 TORC2 complex C
IDA
Spo SPAC23C11.11

GO:0034456 UTP-C complex C
IDA
Sce S000001297
S000005587

GO:0004672 protein kinase activity F
NAS
Dme FBgn0000258

GO:0004674 protein serine/threonine kinase
activity F
IDA
Dme FBgn0000258
Mmu MGI:88547
Sce S000001297
S000005587
ISS
Dme FBgn0000258
Spo SPAC23C11.11
NAS
Dme FBgn0000258

GO:0005515 protein binding F
IPI
Ath At3g50000

GO:0005524 ATP binding F
ISS
Spo SPAC23C11.11

GO:0016301 kinase activity F
IDA
Ath At3g50000
At5g67380
ISS
Ath At3g50000
At5g67380
At2g23070
At2g23080

GO:0030234 enzyme regulator activity F
RCA
Sce S000001297

GO:0000003 reproduction P
IMP
Cel WBGene00002191

GO:0006356 regulation of transcription from RNA polymerase I
promoter P
IDA
Sce S000001297
S000005587

GO:0006359 regulation of transcription from RNA polymerase
III promoter P
IDA
Sce S000001297
S000005587

GO:0006468 protein amino acid phosphorylation P
IC
Spo SPAC23C11.11
IDA
Dme FBgn0000258
Mmu MGI:88547
Sce S000005587
S000001297
IMP
Sce S000001297
ISS
Dme FBgn0000258
NAS
Dme FBgn0000258

GO:0006974 response to DNA damage stimulus P
IDA
Sce S000001297
S000005587

GO:0007163 establishment or maintenance of cell
polarity P
IMP
Spo SPAC23C11.11

GO:0007411 axon guidance P
IMP
Dme FBgn0000258

GO:0007623 circadian rhythm P
IMP
Dme FBgn0000258

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00002191

GO:0016055 Wnt receptor signaling pathway P
IDA
Dme FBgn0000258

GO:0022416 bristle development P
IMP
Dme FBgn0000258

GO:0031929 TOR signaling cascade P
TAS
Spo SPAC23C11.11

GO:0034606 response to hermaphrodite contact P
IMP
Cel WBGene00002191

GO:0034608 vulval location P
IMP
Cel WBGene00002191

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00002191

GO:0040035 hermaphrodite genitalia development P
IMP
Cel WBGene00002191

GO:0045475 locomotor rhythm P
IMP
Dme FBgn0000258

GO:0046331 lateral inhibition P
IMP
Dme FBgn0000258

GO:0048749 compound eye development P
IMP
Dme FBgn0000258

GO:0051726 regulation of cell cycle P
IDA
Mmu MGI:88547

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPAC23C11.11
(P40231) YIL035C
(S000001297)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Spo SPAC23C11.11

GO:0005654 nucleoplasm C
RCA
Sce S000001297

GO:0005730 nucleolus C
IDA
Spo SPAC23C11.11

GO:0005829 cytosol C
IDA
Spo SPAC23C11.11

GO:0005956 protein kinase CK2 complex C
IDA
Sce S000001297
TAS
Spo SPAC23C11.11

GO:0031931 TORC1 complex C
IDA
Spo SPAC23C11.11

GO:0031932 TORC2 complex C
IDA
Spo SPAC23C11.11

GO:0034456 UTP-C complex C
IDA
Sce S000001297

GO:0004674 protein serine/threonine kinase
activity F
IDA
Sce S000001297
ISS
Spo SPAC23C11.11

GO:0005524 ATP binding F
ISS
Spo SPAC23C11.11

GO:0030234 enzyme regulator activity F
RCA
Sce S000001297

GO:0006356 regulation of transcription from RNA polymerase I
promoter P
IDA
Sce S000001297

GO:0006359 regulation of transcription from RNA polymerase
III promoter P
IDA
Sce S000001297

GO:0006468 protein amino acid phosphorylation P
IC
Spo SPAC23C11.11
IDA
Sce S000001297
IMP
Sce S000001297

GO:0006974 response to DNA damage stimulus P
IDA
Sce S000001297

GO:0007163 establishment or maintenance of cell
polarity P
IMP
Spo SPAC23C11.11

GO:0031929 TOR signaling cascade P
TAS
Spo SPAC23C11.11

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YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0668	ACDHYPE

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING	Casein kinase II, alpha subunit

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At2g23070	GI:15227778
Arabidopsis thaliana (Ath)	At2g23080	GI:15227779
Arabidopsis thaliana (Ath)	At3g50000	GI:15229650
Arabidopsis thaliana (Ath)	At5g67380	GI:15240716
Caenorhabditis elegans (Cel)	CE17321 (WBGene00002191)	GI:17505290	P18334
Drosophila melanogaster (Dme)	7289745	GI:17864602	A4V2B8
Homo sapiens (Hsa)	Hs4503095	GI:4503095	P68400
Homo sapiens (Hsa)	Hs4503097 (CSNK2A2)	GI:4503097	P19784
Saccharomyces cerevisiae (Sce)	YIL035c (S000001297)	GI:6322154	P15790
Saccharomyces cerevisiae (Sce)	YOR061w (S000005587)	GI:6324635	P19454
Schizosaccharomyces pombe (Spo)	SPAC23C11.11	GI:19114554	P40231
Encephalitozoon cuniculi (Ecu)	ECU05g1510	GI:19173691	Q8SRU0
Arabidopsis thaliana (Ath)	At2g23070	GI:15227778
Arabidopsis thaliana (Ath)	At2g23080	GI:15227779
Arabidopsis thaliana (Ath)	At3g50000	GI:15229650
Arabidopsis thaliana (Ath)	At5g67380	GI:15240716
Caenorhabditis elegans (Cel)	CE17321 (WBGene00002191)	GI:17505290	P18334
Drosophila melanogaster (Dme)	7289745	GI:17864602	A4V2B8
Homo sapiens (Hsa)	Hs4503095	GI:4503095	P68400
Homo sapiens (Hsa)	Hs4503097 (CSNK2A2)	GI:4503097	P19784
Saccharomyces cerevisiae (Sce)	YIL035c (S000001297)	GI:6322154	P15790
Saccharomyces cerevisiae (Sce)	YOR061w (S000005587)	GI:6324635	P19454
Schizosaccharomyces pombe (Spo)	SPAC23C11.11	GI:19114554	P40231
Encephalitozoon cuniculi (Ecu)	ECU05g1510	GI:19173691	Q8SRU0

Species	Gene ID	NCBI link	UniProt link
Mus musculus (Mmu)	Gm10031	GI:149245220
Mus musculus (Mmu)	Csnk2a1 (MGI:88543)	GI:31542427	Q60737
Drosophila melanogaster (Dme)	CkIIalpha	GI:24668866
Anopheles gambiae (Aga)	AgaP_AGAP005569	GI:158294401
Saccharomyces cerevisiae (Sce)	CKA1 (S000001297)	GI:6322154	P15790
Kluyveromyces lactis (Kla)	KLLA0E04136g	GI:50308269
Eremothecium gossypii (Ego)	AGOS_ADL102C	GI:45187771
Arabidopsis thaliana (Ath)	CKA1	GI:30698301
Arabidopsis thaliana (Ath)	CKA2	GI:30693260
Oryza sativa (Osa)	Os07g0114400	GI:115470307
Plasmodium falciparum (Pfa)	PF11_0096	GI:124803615

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga986	ENSANGP00000017774
Ashbya gossypii (Ago)	ago1639	ADL102C
Ashbya gossypii (Ago)	ago1945	ADR204W
Arabidopsis thaliana (Ath)	ath9212	At2g23070.1
Arabidopsis thaliana (Ath)	ath9213	At2g23080.1
Arabidopsis thaliana (Ath)	ath16313	At3g50000.1
Arabidopsis thaliana (Ath)	ath28922	At5g67380.1
Caenorhabditis elegans (Cel)	cel137	B0205.7 (CE17321; WBGene00002191)
Candida glabrata (Cgl)	cgl1711	CAGL0G02035g
Candida glabrata (Cgl)	cgl2747	CAGL0I05192g
Cryptococcus neoformans (Cne)	cne1449	180.m00403
Dictyostelium discoideum (Ddi)	ddi12128	DDB0185025
Debaryomyces hansenii (Dha)	dha630	DEHA0A14080g
Debaryomyces hansenii (Dha)	dha1762	DEHA0C07469g
Drosophila melanogaster (Dme)	dme10791	CG17520-PA (FBgn0000258)
Drosophila melanogaster (Dme)	dme10793	CG17520-PB (FBgn0000258)
Drosophila melanogaster (Dme)	dme10792	CG17520-PC (FBgn0000258)
Danio rerio (Dre)	dre7486	ENSDARP00000003600 (LOC571171)
Danio rerio (Dre)	dre7485	ENSDARP00000006001 (ck2a1)	Q803N7
Danio rerio (Dre)	dre29489	ENSDARP00000020745
Danio rerio (Dre)	dre22067	ENSDARP00000027027 (ck2a2)	Q7ZU33
Encephalitozoon cuniculi (Ecu)	ecu1253	19173691
Takifugu rubripes (Fru)	fru29594	SINFRUP00000138278
Gallus gallus (Gga)	gga4341	ENSGALP00000001302 (CSNK2A2)	P21869
Gallus gallus (Gga)	gga12070	ENSGALP00000009985 (CSNK2A1)	P21868
Homo sapiens (Hsa)	hsa19634	ENSP00000217244 (CSNK2A1)	P68400
Homo sapiens (Hsa)	hsa12270	ENSP00000262506 (CSNK2A2)	P19784
Homo sapiens (Hsa)	hsa19635	ENSP00000339247 (CSNK2A1)	P68400
Kluyveromyces lactis (Kla)	kla3134	KLLA0E04136g
Kluyveromyces lactis (Kla)	kla4820	KLLA0F16467g
Mus musculus (Mmu)	mmu15738	ENSMUSP00000039756
Mus musculus (Mmu)	mmu26488	ENSMUSP00000055919 (MGI:88547)	O54833
Mus musculus (Mmu)	mmu1279	ENSMUSP00000079835
Neurospora crassa (Ncr)	ncr3028	NCU03124.2
Oryza sativa (Osa)	osa50269	5904.m00136
Oryza sativa (Osa)	osa51905	5988.m00131
Oryza sativa (Osa)	osa66911	6940.m00150
Plasmodium falciparum (Pfa)	pfa1044	PF11_0096
Rattus norvegicus (Rno)	rno19977	ENSRNOP00000007558 (RGD:621663)	P19139
Rattus norvegicus (Rno)	rno14545	ENSRNOP00000016386 (RGD:1306882)	B4F7A9
Saccharomyces cerevisiae (Sce)	sce3049	YIL035C (S000001297)
Saccharomyces cerevisiae (Sce)	sce5795	YOR061W (S000005587)
Schizosaccharomyces pombe (Spo)	spo4936	SPAC23C11.11	P40231
Yarrowia lipolytica (Yli)	yli1524	YALI0B18700g
Yarrowia lipolytica (Yli)	yli3401	YALI0D16863g

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC23C11.11 (P40231)	YIL035C (S000001297)