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Search term: YIL044C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name AGE2
SGD link S000001306
Alternative ID YIL044C
Description ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif
Synonyms YIL044C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0703 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted GTPase-activating protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g14490 GI:15225946
Arabidopsis thaliana (Ath) At3g07940_1 GI:15231898
Arabidopsis thaliana (Ath) At3g17660 GI:15229090
Arabidopsis thaliana (Ath) At4g05330_1 GI:7267293
Arabidopsis thaliana (Ath) At4g21160_1 GI:7486586
Arabidopsis thaliana (Ath) At5g54310 GI:18423615
Caenorhabditis elegans (Cel) CE16562
(WBGene00012359)		 GI:17555530 O18181
Drosophila melanogaster (Dme) 7303978 GI:7303978
Homo sapiens (Hsa) Hs17441611 GI:17441611
Homo sapiens (Hsa) Hs21264558 GI:16303738 Q8IYB5
Homo sapiens (Hsa) Hs6806913
(ADAP1)		 GI:6806913 O75689
Homo sapiens (Hsa) Hs8923763
(ADAP2)		 GI:8923763 Q9NPF8
Homo sapiens (Hsa) HsM11345478 GI:11345478
Saccharomyces cerevisiae (Sce) YGL181w_1 GI:6321257 P40956
Saccharomyces cerevisiae (Sce) YIL044c
(S000001306)		 GI:6322145 P40529
Schizosaccharomyces pombe (Spo) SPAC824.09c GI:19114360 Q9UT34
Schizosaccharomyces pombe (Spo) SPBC21D10.05c_1 GI:19112800 O74345
Arabidopsis thaliana (Ath) At2g14490 GI:15225946
Arabidopsis thaliana (Ath) At3g07940_1 GI:15231898
Arabidopsis thaliana (Ath) At3g17660 GI:15229090
Arabidopsis thaliana (Ath) At4g05330_1 GI:7267293
Arabidopsis thaliana (Ath) At4g21160_1 GI:7486586
Arabidopsis thaliana (Ath) At5g54310 GI:18423615
Caenorhabditis elegans (Cel) CE16562
(WBGene00012359)		 GI:17555530 O18181
Drosophila melanogaster (Dme) 7303978 GI:7303978
Homo sapiens (Hsa) Hs17441611 GI:17441611
Homo sapiens (Hsa) Hs21264558 GI:16303738 Q8IYB5
Homo sapiens (Hsa) Hs6806913
(ADAP1)		 GI:6806913 O75689
Homo sapiens (Hsa) Hs8923763
(ADAP2)		 GI:8923763 Q9NPF8
Homo sapiens (Hsa) HsM11345478 GI:11345478
Saccharomyces cerevisiae (Sce) YGL181w_1 GI:6321257 P40956
Saccharomyces cerevisiae (Sce) YIL044c
(S000001306)		 GI:6322145 P40529
Schizosaccharomyces pombe (Spo) SPAC824.09c GI:19114360 Q9UT34
Schizosaccharomyces pombe (Spo) SPBC21D10.05c_1 GI:19112800 O74345


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g07940
GO:0005634 nucleus C
IDA
HsaADAP1
ISS
AthAt5g54310
At3g17660
GO:0005737 cytoplasm C
IDA
HsaADAP1
ADAP2
SpoSPAC824.09c
GO:0005740 mitochondrial envelope C
ISS
HsaADAP2
GO:0005768 endosome C
IDA
AthAt5g54310
GO:0005773 vacuole C
IDA
AthAt4g21160
GO:0005794 Golgi apparatus C
IDA
AthAt4g21160
SpoSPAC824.09c
GO:0005802 trans-Golgi network C
IDA
AthAt5g54310
GO:0005829 cytosol C
IDA
AthAt5g54310
SpoSPBC21D10.05c
GO:0005886 plasma membrane C
IDA
AthAt4g21160
HsaADAP1
ADAP2
GO:0016020 membrane C
IDA
AthAt4g21160
GO:0030136 clathrin-coated vesicle C
IDA
SceS000001306
ISS
SpoSPAC824.09c
GO:0030479 actin cortical patch C
ISS
SpoSPBC21D10.05c
GO:0032153 cell division site C
IDA
SpoSPBC21D10.05c
GO:0051286 cell tip C
IDA
SpoSPBC21D10.05c
GO:0003677 DNA binding F
ISS
AthAt5g54310
At3g17660
GO:0005096 GTPase activator activity F
NAS
HsaADAP2
GO:0005515 protein binding F
IPI
HsaADAP1
ADAP2
GO:0005543 phospholipid binding F
IDA
AthAt4g21160
GO:0005546 phosphatidylinositol-4,5-bisphosphate
binding		 F
ISS
HsaADAP2
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate
binding		 F
IDA
HsaADAP2
GO:0008060 ARF GTPase activator activity F
IDA
AthAt4g21160
HsaADAP1
SceS000001306
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
SPBC21D10.05c
GO:0030674 protein binding, bridging F
NAS
HsaADAP2
GO:0031593 polyubiquitin binding F
TAS
SpoSPBC21D10.05c
GO:0043130 ubiquitin binding F
ISS
SpoSPBC21D10.05c
GO:0043325 phosphatidylinositol-3,4-bisphosphate
binding		 F
ISS
HsaADAP2
GO:0043533 inositol 1,3,4,5 tetrakisphosphate
binding		 F
IDA
HsaADAP2
TAS
HsaADAP1
GO:0002119 nematode larval development P
IMP
CelWBGene00012359
GO:0006414 translational elongation P
RCA
SceS000001306
GO:0006886 intracellular protein transport P
TAS
AthAt4g21160
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006897 endocytosis P
ISS
SpoSPBC21D10.05c
GO:0007166 cell surface receptor linked signaling
pathway		 P
TAS
HsaADAP1
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC21D10.05c
GO:0007507 heart development P
IEP
HsaADAP2
GO:0010227 floral organ abscission P
IMP
AthAt5g54310
GO:0019915 lipid storage P
IMP
CelWBGene00012359
GO:0032857 activation of ARF GTPase activity P
IDA
AthAt5g54310
GO:0040007 growth P
IMP
CelWBGene00012359
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00012359
GO:0043087 regulation of GTPase activity P
IMP
HsaADAP1
GO:0051056 regulation of small GTPase mediated signal
transduction		 P
IC
SpoSPAC824.09c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117833

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC824.09c GI:19114360 Q9UT34
Saccharomyces cerevisiae (Sce) AGE2
(S000001306)		 GI:6322145 P40529
Kluyveromyces lactis (Kla) KLLA0F27555g GI:50312541
Eremothecium gossypii (Ego) AGOS_ADL084W GI:45187789
Magnaporthe grisea (Mgr) MGG_04954 GI:39940572
Neurospora crassa (Ncr) NCU03890.1 GI:32405192


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPAC824.09c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.09c
GO:0030136 clathrin-coated vesicle C
IDA
SceS000001306
ISS
SpoSPAC824.09c
GO:0008060 ARF GTPase activator activity F
IDA
SceS000001306
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006414 translational elongation P
RCA
SceS000001306
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0051056 regulation of small GTPase mediated signal
transduction		 P
IC
SpoSPAC824.09c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1232

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9277 ENSANGP00000016918
Anopheles gambiae (Aga) aga12939 ENSANGP00000026979
Ashbya gossypii (Ago) ago1657 ADL084W
Arabidopsis thaliana (Ath) ath27411 At5g54310.1
Caenorhabditis elegans (Cel) cel17302 W09D10.1
(CE16562;
WBGene00012359)
Candida glabrata (Cgl) cgl4114 CAGL0L00825g
Cryptococcus neoformans (Cne) cne3257 167.m03607
Debaryomyces hansenii (Dha) dha1084 DEHA0B09438g
Drosophila melanogaster (Dme) dme3964 CG8243-PA
(FBgn0033349)
Danio rerio (Dre) dre10575 ENSDARP00000026587
Danio rerio (Dre) dre15115 ENSDARP00000041035 Q08BF0
Danio rerio (Dre) dre19674 ENSDARP00000050225
Takifugu rubripes (Fru) fru9959 SINFRUP00000147143
Takifugu rubripes (Fru) fru22226 SINFRUP00000159156
Takifugu rubripes (Fru) fru6973 SINFRUP00000164716
Gallus gallus (Gga) gga15811 ENSGALP00000025669
Gallus gallus (Gga) gga15812 ENSGALP00000025670
Gallus gallus (Gga) gga15813 ENSGALP00000025671
Homo sapiens (Hsa) hsa933 ENSP00000196802
Homo sapiens (Hsa) hsa27382 ENSP00000264842
Homo sapiens (Hsa) hsa27381 ENSP00000264843
Homo sapiens (Hsa) hsa27380 ENSP00000313382
(SMAP1)		 Q8IYB5-2
Kluyveromyces lactis (Kla) kla5306 KLLA0F27555g
Mus musculus (Mmu) mmu115 ENSMUSP00000027339
(MGI:2138261)		 Q91VZ6
Mus musculus (Mmu) mmu18816 ENSMUSP00000035800
(MGI:1917030)		 Q7TN29-1
Neurospora crassa (Ncr) ncr3779 NCU03890.2
Oryza sativa (Osa) osa20265 3528.m00147
Oryza sativa (Osa) osa20277 3528.m00153
Oryza sativa (Osa) osa46562 5713.m00059
Oryza sativa (Osa) osa53197 6128.m00096
Plasmodium falciparum (Pfa) pfa3711 PFE1305c
Rattus norvegicus (Rno) rno23857 ENSRNOP00000015250
(RGD:1308418)		 B1WBX6
Saccharomyces cerevisiae (Sce) sce3058 YIL044C
(S000001306)
Schizosaccharomyces pombe (Spo) spo1600 SPAC824.09c Q9UT34
Yarrowia lipolytica (Yli) yli5943 YALI0F14267g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2138261
GO:0005634 nucleus C
ISS
AthAt5g54310
GO:0005737 cytoplasm C
IDA
SpoSPAC824.09c
GO:0005768 endosome C
IDA
AthAt5g54310
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.09c
GO:0005802 trans-Golgi network C
IDA
AthAt5g54310
GO:0005829 cytosol C
IDA
AthAt5g54310
GO:0030136 clathrin-coated vesicle C
IDA
SceS000001306
ISS
SpoSPAC824.09c
GO:0003674 molecular_function F
ND
MmuMGI:2138261
GO:0003677 DNA binding F
ISS
AthAt5g54310
GO:0008060 ARF GTPase activator activity F
IDA
SceS000001306
IGI
SceS000001306
ISS
DmeFBgn0033349
SceS000001306
SpoSPAC824.09c
GO:0002119 nematode larval development P
IMP
CelWBGene00012359
GO:0006414 translational elongation P
RCA
SceS000001306
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0010227 floral organ abscission P
IMP
AthAt5g54310
GO:0019915 lipid storage P
IMP
CelWBGene00012359
GO:0032857 activation of ARF GTPase activity P
IDA
AthAt5g54310
GO:0040007 growth P
IMP
CelWBGene00012359
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00012359
GO:0045648 positive regulation of erythrocyte
differentiation		 P
IDA
MmuMGI:2138261
GO:0051056 regulation of small GTPase mediated signal
transduction		 P
IC
SpoSPAC824.09c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC824.09c
(Q9UT34)		 YIL044C
(S000001306)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPAC824.09c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.09c
GO:0030136 clathrin-coated vesicle C
IDA
SceS000001306
ISS
SpoSPAC824.09c
GO:0008060 ARF GTPase activator activity F
IDA
SceS000001306
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006414 translational elongation P
RCA
SceS000001306
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000001306
ISS
SceS000001306
SpoSPAC824.09c
GO:0051056 regulation of small GTPase mediated signal
transduction		 P
IC
SpoSPAC824.09c

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