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Search term: YIL048W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NEO1
SGD link S000001310
Alternative ID YIL048W
Description Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
Synonyms YIL048W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0210 -CDHYPE

KOGs classification KOGs description
METABOLISM P-type ATPase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE15993 GI:17507223
Caenorhabditis elegans (Cel) CE19775
(WBGene00017174)		 GI:17559268 P91203
Drosophila melanogaster (Dme) 7298039 GI:7298039
Homo sapiens (Hsa) Hs20554338 GI:20554338
Homo sapiens (Hsa) Hs22058729 GI:22058729
Homo sapiens (Hsa) Hs22058732 GI:22058732
Homo sapiens (Hsa) Hs22062141 GI:22062141
Saccharomyces cerevisiae (Sce) YIL048w
(S000001310)		 GI:6322141 P40527
Schizosaccharomyces pombe (Spo) SPAC6C3.06c GI:19114632 Q10309
Encephalitozoon cuniculi (Ecu) ECU09g1440 GI:19173265
Caenorhabditis elegans (Cel) CE15993 GI:17507223
Caenorhabditis elegans (Cel) CE19775
(WBGene00017174)		 GI:17559268 P91203
Drosophila melanogaster (Dme) 7298039 GI:7298039
Homo sapiens (Hsa) Hs20554338 GI:20554338
Homo sapiens (Hsa) Hs22058729 GI:22058729
Homo sapiens (Hsa) Hs22058732 GI:22058732
Homo sapiens (Hsa) Hs22062141 GI:22062141
Saccharomyces cerevisiae (Sce) YIL048w
(S000001310)		 GI:6322141 P40527
Schizosaccharomyces pombe (Spo) SPAC6C3.06c GI:19114632 Q10309
Encephalitozoon cuniculi (Ecu) ECU09g1440 GI:19173265
Caenorhabditis elegans (Cel) CE15993 GI:17507223
Caenorhabditis elegans (Cel) CE19775
(WBGene00017174)		 GI:17559268 P91203
Drosophila melanogaster (Dme) 7298039 GI:7298039
Homo sapiens (Hsa) Hs20554338 GI:20554338
Homo sapiens (Hsa) Hs22058729 GI:22058729
Homo sapiens (Hsa) Hs22058732 GI:22058732
Homo sapiens (Hsa) Hs22062141 GI:22062141
Saccharomyces cerevisiae (Sce) YIL048w
(S000001310)		 GI:6322141 P40527
Schizosaccharomyces pombe (Spo) SPAC6C3.06c GI:19114632 Q10309
Encephalitozoon cuniculi (Ecu) ECU09g1440 GI:19173265


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000001310
GO:0005768 endosome C
IDA
SceS000001310
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC6C3.06c
GO:0005794 Golgi apparatus C
IDA
SceS000001310
SpoSPAC6C3.06c
GO:0030137 COPI-coated vesicle C
IDA
SceS000001310
GO:0004012 phospholipid-translocating ATPase
activity		 F
ISS
SceS000001310
SpoSPAC6C3.06c
GO:0005388 calcium-transporting ATPase activity F
ISS
SpoSPAC6C3.06c
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
ISS
SceS000001310
GO:0006869 lipid transport P
RCA
SceS000001310
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000001310
ISS
SpoSPAC6C3.06c
GO:0006897 endocytosis P
IMP
SceS000001310
GO:0007033 vacuole organization P
IMP
SceS000001310
GO:0009117 nucleotide metabolic process P
RCA
SceS000001310
GO:0070588 calcium ion transmembrane transport P
TAS
SpoSPAC6C3.06c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
21915

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATP9B GI:41327760
Pan troglodytes (Ptr) ATP9B GI:114673706
Canis familiaris (Cfa) ATP9B GI:73945359
Mus musculus (Mmu) Atp9b
(MGI:1354757)		 GI:40807502 P98195
Rattus norvegicus (Rno) Atp9b GI:62664679
Drosophila melanogaster (Dme) CG31729
(FBgn0051729)		 GI:20301938
Anopheles gambiae (Aga) AgaP_AGAP008184 GI:158296962
Caenorhabditis elegans (Cel) tat-5
(CE34183;
WBGene00009498)		 GI:115532300
Caenorhabditis elegans (Cel) tat-6
(CE19775;
WBGene00017174)		 GI:17559268 P91203
Schizosaccharomyces pombe (Spo) SPAC6C3.06c GI:19114632 Q10309
Saccharomyces cerevisiae (Sce) NEO1
(S000001310)		 GI:6322141 P40527
Kluyveromyces lactis (Kla) KLLA0C08393g GI:50305229
Eremothecium gossypii (Ego) AGOS_ADL079C GI:45187794
Magnaporthe grisea (Mgr) MGG_04066 GI:145607199
Neurospora crassa (Ncr) NCU03818.1 GI:32405012
Plasmodium falciparum (Pfa) PFL1125w GI:124806112


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000001310
GO:0005768 endosome C
IDA
SceS000001310
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC6C3.06c
GO:0005794 Golgi apparatus C
IDA
SceS000001310
SpoSPAC6C3.06c
GO:0016021 integral to membrane C
NAS
HsaATP9B
GO:0030137 COPI-coated vesicle C
IDA
SceS000001310
GO:0004012 phospholipid-translocating ATPase
activity		 F
ISS
PfaPFL1125w
SceS000001310
SpoSPAC6C3.06c
GO:0005388 calcium-transporting ATPase activity F
ISS
SpoSPAC6C3.06c
GO:0005524 ATP binding F
NAS
HsaATP9B
GO:0015247 aminophospholipid transporter activity F
NAS
HsaATP9B
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
ISS
DmeFBgn0051729
SceS000001310
GO:0019829 cation-transporting ATPase activity F
NAS
HsaATP9B
GO:0000003 reproduction P
IMP
CelWBGene00009498
GO:0006812 cation transport P
ISS
DmeFBgn0051729
GO:0006869 lipid transport P
RCA
SceS000001310
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000001310
ISS
SpoSPAC6C3.06c
GO:0006897 endocytosis P
IMP
SceS000001310
GO:0007033 vacuole organization P
IMP
SceS000001310
GO:0009117 nucleotide metabolic process P
RCA
SceS000001310
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009498
GO:0015917 aminophospholipid transport P
ISS
PfaPFL1125w
NAS
HsaATP9B
GO:0032502 developmental process P
IMP
CelWBGene00009498
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009498
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00009498
GO:0070588 calcium ion transmembrane transport P
TAS
SpoSPAC6C3.06c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1069

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10164 ENSANGP00000006830
Anopheles gambiae (Aga) aga10165 ENSANGP00000028227
Ashbya gossypii (Ago) ago1662 ADL079C
Caenorhabditis elegans (Cel) cel5438 F02C9.3
(CE19775;
WBGene00017174)
Caenorhabditis elegans (Cel) cel8342 F36H2.1a
(CE34183;
WBGene00009498)
Caenorhabditis elegans (Cel) cel8343 F36H2.1b
(CE34184)
Candida glabrata (Cgl) cgl4109 CAGL0L00715g
Dictyostelium discoideum (Ddi) ddi1841 DDB0216656
Debaryomyces hansenii (Dha) dha2951 DEHA0D14608g
Drosophila melanogaster (Dme) dme2254 CG31729-PA
(FBgn0051729)
Drosophila melanogaster (Dme) dme2253 CG31729-PB
(FBgn0051729)
Danio rerio (Dre) dre9934 ENSDARP00000003419
Danio rerio (Dre) dre9937 ENSDARP00000016662
Danio rerio (Dre) dre9936 ENSDARP00000027854
Danio rerio (Dre) dre9933 ENSDARP00000041203
Danio rerio (Dre) dre9935 ENSDARP00000049584
Encephalitozoon cuniculi (Ecu) ecu1416 19173265
Takifugu rubripes (Fru) fru31461 SINFRUP00000169242
Takifugu rubripes (Fru) fru31460 SINFRUP00000175054
Gallus gallus (Gga) gga12235 ENSGALP00000012832
Gallus gallus (Gga) gga12236 ENSGALP00000012833
Gallus gallus (Gga) gga12237 ENSGALP00000012834
(ATP9A)
Gallus gallus (Gga) gga10387 ENSGALP00000020629
(ATP9B)
Gallus gallus (Gga) gga10388 ENSGALP00000020630
(ATP9B)		 Q5ZKC0
Homo sapiens (Hsa) hsa15115 ENSP00000304500
(ATP9B)		 O43861-1
Homo sapiens (Hsa) hsa20432 ENSP00000309086
(ATP9A)		 O75110-2
Homo sapiens (Hsa) hsa20433 ENSP00000342481
(ATP9A)		 O75110-1
Homo sapiens (Hsa) hsa15117 ENSP00000352108
(ATP9B)		 A6NH10
Kluyveromyces lactis (Kla) kla1572 KLLA0C08393g
Mus musculus (Mmu) mmu12975 ENSMUSP00000025458
(MGI:1354757)		 P98195-1
Mus musculus (Mmu) mmu16083 ENSMUSP00000029060
(MGI:1330826)		 O70228
Mus musculus (Mmu) mmu12976 ENSMUSP00000077619
Neurospora crassa (Ncr) ncr3708 NCU03818.2
Plasmodium falciparum (Pfa) pfa5008 PFL1125w
Rattus norvegicus (Rno) rno14453 ENSRNOP00000040756
(RGD:1563006)
Rattus norvegicus (Rno) rno14454 ENSRNOP00000048354
(RGD:1563006)		 Q5XFX3
Saccharomyces cerevisiae (Sce) sce3064 YIL048W
(S000001310)
Schizosaccharomyces pombe (Spo) spo2886 SPAC6C3.06c Q10309
Yarrowia lipolytica (Yli) yli5381 YALI0F01122g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000001310
GO:0005768 endosome C
IDA
SceS000001310
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC6C3.06c
GO:0005794 Golgi apparatus C
IDA
SceS000001310
SpoSPAC6C3.06c
GO:0030137 COPI-coated vesicle C
IDA
SceS000001310
GO:0004012 phospholipid-translocating ATPase
activity		 F
ISS
PfaPFL1125w
SceS000001310
SpoSPAC6C3.06c
GO:0005388 calcium-transporting ATPase activity F
ISS
SpoSPAC6C3.06c
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
ISS
DmeFBgn0051729
SceS000001310
GO:0000003 reproduction P
IMP
CelWBGene00009498
GO:0006812 cation transport P
ISS
DmeFBgn0051729
GO:0006869 lipid transport P
RCA
SceS000001310
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000001310
ISS
SpoSPAC6C3.06c
GO:0006897 endocytosis P
IMP
SceS000001310
GO:0007033 vacuole organization P
IMP
SceS000001310
GO:0009117 nucleotide metabolic process P
RCA
SceS000001310
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009498
GO:0015917 aminophospholipid transport P
ISS
PfaPFL1125w
GO:0032502 developmental process P
IMP
CelWBGene00009498
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009498
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00009498
GO:0070588 calcium ion transmembrane transport P
TAS
SpoSPAC6C3.06c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC6C3.06c
(Q10309)		 YIL048W
(S000001310)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000001310
GO:0005768 endosome C
IDA
SceS000001310
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC6C3.06c
GO:0005794 Golgi apparatus C
IDA
SceS000001310
SpoSPAC6C3.06c
GO:0030137 COPI-coated vesicle C
IDA
SceS000001310
GO:0004012 phospholipid-translocating ATPase
activity		 F
ISS
SceS000001310
SpoSPAC6C3.06c
GO:0005388 calcium-transporting ATPase activity F
ISS
SpoSPAC6C3.06c
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
ISS
SceS000001310
GO:0006869 lipid transport P
RCA
SceS000001310
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000001310
ISS
SpoSPAC6C3.06c
GO:0006897 endocytosis P
IMP
SceS000001310
GO:0007033 vacuole organization P
IMP
SceS000001310
GO:0009117 nucleotide metabolic process P
RCA
SceS000001310
GO:0070588 calcium ion transmembrane transport P
TAS
SpoSPAC6C3.06c

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