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Search term: YIL066C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RNR3
SGD link S000001328
Alternative ID YIL066C
Description One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits
Synonyms YIL066C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1112 ACDHYPE

KOGs classification KOGs description
METABOLISM Ribonucleotide reductase, alpha subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g21790 GI:15227096
Caenorhabditis elegans (Cel) CE00331
(WBGene00004391)		 GI:17555242 Q03604
Drosophila melanogaster (Dme) 7297661 GI:7297661
Homo sapiens (Hsa) Hs4506749
(RRM1)		 GI:4506749 P23921
Saccharomyces cerevisiae (Sce) YER070w
(S000000872)		 GI:6320914 P21524
Saccharomyces cerevisiae (Sce) YIL066c
(S000001328)		 GI:6322123 P21672
Schizosaccharomyces pombe (Spo) SPAC1F7.05 GI:19115403 P36602
Encephalitozoon cuniculi (Ecu) ECU10g0920 GI:19074701 Q8SR37
Arabidopsis thaliana (Ath) At2g21790 GI:15227096
Caenorhabditis elegans (Cel) CE00331
(WBGene00004391)		 GI:17555242 Q03604
Drosophila melanogaster (Dme) 7297661 GI:7297661
Homo sapiens (Hsa) Hs4506749
(RRM1)		 GI:4506749 P23921
Saccharomyces cerevisiae (Sce) YER070w
(S000000872)		 GI:6320914 P21524
Saccharomyces cerevisiae (Sce) YIL066c
(S000001328)		 GI:6322123 P21672
Schizosaccharomyces pombe (Spo) SPAC1F7.05 GI:19115403 P36602
Encephalitozoon cuniculi (Ecu) ECU10g0920 GI:19074701 Q8SR37


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001328
S000000872
SpoSPAC1F7.05
TAS
SpoSPAC1F7.05
GO:0005739 mitochondrion C
IDA
SceS000001328
GO:0005829 cytosol C
IDA
SpoSPAC1F7.05
GO:0005971 ribonucleoside-diphosphate reductase
complex		 C
IDA
SceS000000872
ISS
AthAt2g21790
NAS
HsaRRM1
TAS
SceS000001328
SpoSPAC1F7.05
GO:0000166 nucleotide binding F
IDA
SceS000000872
GO:0004748 ribonucleoside-diphosphate reductase
activity		 F
IDA
SceS000001328
S000000872
S000000872
IMP
SceS000000872
SpoSPAC1F7.05
ISS
AthAt2g21790
HsaRRM1
NAS
HsaRRM1
GO:0005515 protein binding F
IPI
SpoSPAC1F7.05
GO:0005524 ATP binding F
ISS
SpoSPAC1F7.05
GO:0000003 reproduction P
IMP
CelWBGene00004391
GO:0002119 nematode larval development P
IMP
CelWBGene00004391
GO:0006213 pyrimidine nucleoside metabolic
process		 P
IC
SpoSPAC1F7.05
GO:0006260 DNA replication P
IMP
AthAt2g21790
ISS
AthAt2g21790
NAS
HsaRRM1
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPAC1F7.05
GO:0009202 deoxyribonucleoside triphosphate biosynthetic
process		 P
IMP
AthAt2g21790
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
IDA
SceS000000872
S000001328
ISS
HsaRRM1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004391
GO:0040007 growth P
IMP
CelWBGene00004391
GO:0040011 locomotion P
IMP
CelWBGene00004391
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00004391
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004391
GO:0042278 purine nucleoside metabolic process P
IC
SpoSPAC1F7.05
GO:0046686 response to cadmium ion P
IEP
AthAt2g21790
GO:0090329 regulation of DNA-dependent DNA
replication		 P
IMP
SpoSPAC1F7.05

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
806

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RRM1 GI:4506749 P23921
Pan troglodytes (Ptr) RRM1 GI:114635715
Canis familiaris (Cfa) RRM1 GI:73988079
Mus musculus (Mmu) Rrm1
(MGI:98180)		 GI:31982026 P07742
Rattus norvegicus (Rno) Rrm1-ps1 GI:109499829
Gallus gallus (Gga) RRM1 GI:71895081
Drosophila melanogaster (Dme) RnrL
(FBgn0011703)		 GI:17352481
Anopheles gambiae (Aga) AgaP_AGAP010198 GI:158299261
Caenorhabditis elegans (Cel) rnr-1
(CE00331;
WBGene00004391)		 GI:17555242 Q03604
Schizosaccharomyces pombe (Spo) cdc22
(SPAC1F7.05)		 GI:19115403 P36602
Saccharomyces cerevisiae (Sce) RNR1
(S000000872)		 GI:6320914 P21524
Saccharomyces cerevisiae (Sce) RNR3
(S000001328)		 GI:6322123 P21672
Kluyveromyces lactis (Kla) KLLA0C07887g GI:50305185
Eremothecium gossypii (Ego) AGOS_ADL057W GI:45187816
Magnaporthe grisea (Mgr) MGG_07000 GI:39978231
Neurospora crassa (Ncr) NCU03539.1 GI:32404368
Arabidopsis thaliana (Ath) RNR1 GI:15227096
Oryza sativa (Osa) Os06g0168600 GI:115466654
Oryza sativa (Osa) Os02g0804900 GI:115449311
Plasmodium falciparum (Pfa) PF14_0352 GI:124809244


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001328
S000000872
SpoSPAC1F7.05
TAS
SpoSPAC1F7.05
GO:0005739 mitochondrion C
IDA
SceS000001328
GO:0005829 cytosol C
IDA
SpoSPAC1F7.05
GO:0005971 ribonucleoside-diphosphate reductase
complex		 C
IDA
SceS000000872
ISS
AthRNR1
DmeFBgn0011703
NAS
HsaRRM1
TAS
SceS000001328
SpoSPAC1F7.05
GO:0009507 chloroplast C
IDA
AthRNR1
GO:0000166 nucleotide binding F
IDA
SceS000000872
GO:0004748 ribonucleoside-diphosphate reductase
activity		 F
IDA
MmuMGI:98180
MGI:98180
SceS000001328
S000000872
S000000872
IMP
SceS000000872
SpoSPAC1F7.05
ISS
AthRNR1
DmeFBgn0011703
HsaRRM1
NAS
DmeFBgn0011703
HsaRRM1
GO:0005515 protein binding F
IPI
MmuMGI:98180
SpoSPAC1F7.05
GO:0005524 ATP binding F
ISS
SpoSPAC1F7.05
GO:0017076 purine nucleotide binding F
IDA
MmuMGI:98180
GO:0000003 reproduction P
IMP
CelWBGene00004391
GO:0002119 nematode larval development P
IMP
CelWBGene00004391
GO:0006213 pyrimidine nucleoside metabolic
process		 P
IC
SpoSPAC1F7.05
GO:0006260 DNA replication P
IMP
AthRNR1
ISS
AthRNR1
NAS
DmeFBgn0011703
HsaRRM1
GO:0006919 activation of caspase activity P
IMP
DmeFBgn0011703
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPAC1F7.05
GO:0009202 deoxyribonucleoside triphosphate biosynthetic
process		 P
IMP
AthRNR1
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
IDA
MmuMGI:98180
SceS000000872
S000001328
ISS
HsaRRM1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004391
GO:0040007 growth P
IMP
CelWBGene00004391
GO:0040011 locomotion P
IMP
CelWBGene00004391
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00004391
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004391
GO:0042278 purine nucleoside metabolic process P
IC
SpoSPAC1F7.05
GO:0046686 response to cadmium ion P
IEP
AthRNR1
GO:0051259 protein oligomerization P
IPI
MmuMGI:98180
GO:0051290 protein heterotetramerization P
IPI
MmuMGI:98180
GO:0090329 regulation of DNA-dependent DNA
replication		 P
IMP
SpoSPAC1F7.05

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_433

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12504 ENSANGP00000012190
Anopheles gambiae (Aga) aga12503 ENSANGP00000025683
Anopheles gambiae (Aga) aga12706 ENSANGP00000027292
Ashbya gossypii (Ago) ago1202 ACR155W
Ashbya gossypii (Ago) ago1684 ADL057W
Arabidopsis thaliana (Ath) ath9074 At2g21790.1
Caenorhabditis elegans (Cel) cel16172 T23G5.1
(CE00331;
WBGene00004391)
Candida glabrata (Cgl) cgl3124 CAGL0J03146g
Cryptococcus neoformans (Cne) cne3143 167.m03479
Dictyostelium discoideum (Ddi) ddi12909 DDB0230075
Debaryomyces hansenii (Dha) dha5978 DEHA0G06248g
Debaryomyces hansenii (Dha) dha6794 DEHA0G24618g
Drosophila melanogaster (Dme) dme1788 CG5371-PA
(FBgn0011703)
Danio rerio (Dre) dre13708 ENSDARP00000010800
(rrm1)		 P79732
Escherichia coli (Eco) eco2163 16130169
Escherichia coli (Eco) eco2588 16130589
Encephalitozoon cuniculi (Ecu) ecu617 19074701
Takifugu rubripes (Fru) fru2817 SINFRUP00000141958
Takifugu rubripes (Fru) fru26005 SINFRUP00000152532
Gallus gallus (Gga) gga3545 ENSGALP00000027981
(RRM1)		 Q5ZM69
Gallus gallus (Gga) gga25590 ENSGALP00000028241
Homo sapiens (Hsa) hsa5012 ENSP00000300738
(RRM1)		 P23921
Kluyveromyces lactis (Kla) kla1550 KLLA0C07887g
Kluyveromyces lactis (Kla) kla4132 KLLA0F01188g
Mus musculus (Mmu) mmu24592 ENSMUSP00000033283
(MGI:98180)		 Q05DU8
Neurospora crassa (Ncr) ncr3430 NCU03539.2
Oryza sativa (Osa) osa7582 2548.m00124
Oryza sativa (Osa) osa15099 3025.m00153
Oryza sativa (Osa) osa19060 3351.m00141
Plasmodium falciparum (Pfa) pfa1803 PF14_0352
Saccharomyces cerevisiae (Sce) sce1795 YER070W
(S000000872)
Saccharomyces cerevisiae (Sce) sce3082 YIL066C
(S000001328)
Schizosaccharomyces pombe (Spo) spo1214 SPAC1F7.05 P36602
Yarrowia lipolytica (Yli) yli2844 YALI0D03333g
Yarrowia lipolytica (Yli) yli6651 YALI0F31735g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001328
S000000872
SpoSPAC1F7.05
TAS
SpoSPAC1F7.05
GO:0005739 mitochondrion C
IDA
SceS000001328
GO:0005829 cytosol C
IDA
SpoSPAC1F7.05
GO:0005971 ribonucleoside-diphosphate reductase
complex		 C
IDA
SceS000000872
ISS
AthAt2g21790
DmeFBgn0011703
TAS
SceS000001328
SpoSPAC1F7.05
GO:0000166 nucleotide binding F
IDA
SceS000000872
GO:0004748 ribonucleoside-diphosphate reductase
activity		 F
IDA
MmuMGI:98180
MGI:98180
SceS000001328
S000000872
S000000872
IMP
SceS000000872
SpoSPAC1F7.05
ISS
AthAt2g21790
DmeFBgn0011703
NAS
DmeFBgn0011703
GO:0005515 protein binding F
IPI
MmuMGI:98180
SpoSPAC1F7.05
GO:0005524 ATP binding F
ISS
SpoSPAC1F7.05
GO:0017076 purine nucleotide binding F
IDA
MmuMGI:98180
GO:0000003 reproduction P
IMP
CelWBGene00004391
GO:0002119 nematode larval development P
IMP
CelWBGene00004391
GO:0006213 pyrimidine nucleoside metabolic
process		 P
IC
SpoSPAC1F7.05
GO:0006260 DNA replication P
IMP
AthAt2g21790
ISS
AthAt2g21790
NAS
DmeFBgn0011703
GO:0006919 activation of caspase activity P
IMP
DmeFBgn0011703
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPAC1F7.05
GO:0009202 deoxyribonucleoside triphosphate biosynthetic
process		 P
IMP
AthAt2g21790
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthetic process		 P
IC
SpoSPAC1F7.05
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
IDA
MmuMGI:98180
SceS000000872
S000001328
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004391
GO:0040007 growth P
IMP
CelWBGene00004391
GO:0040011 locomotion P
IMP
CelWBGene00004391
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00004391
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004391
GO:0042278 purine nucleoside metabolic process P
IC
SpoSPAC1F7.05
GO:0046686 response to cadmium ion P
IEP
AthAt2g21790
GO:0051259 protein oligomerization P
IPI
MmuMGI:98180
GO:0051290 protein heterotetramerization P
IPI
MmuMGI:98180
GO:0090329 regulation of DNA-dependent DNA
replication		 P
IMP
SpoSPAC1F7.05

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1F7.05
(P36602)		 YIL066C
(S000001328)